Page last updated: 2024-11-08

serine and Kidney Neoplasms

serine has been researched along with Kidney Neoplasms in 14 studies

Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.

Kidney Neoplasms: Tumors or cancers of the KIDNEY.

Research Excerpts

ExcerptRelevanceReference
"Azaserine was selected because it behaves as a direct-acting mutagen in two bacterial test systems and because tissue distribution studies showed concentration especially in kidney and pancreas."5.25Adenocarcinoma of the pancreas in azaserine-treated rats. ( Curphey, TJ; Longnecker, DS, 1975)
"In vivo, teratomas were examined for tumor size, proliferation, apoptosis, and immunohistochemistry and subjected to gene expression analysis."1.39Pleiotropic effects of the trichloroethylene-associated P81S VHL mutation on metabolism, apoptosis, and ATM-mediated DNA damage response. ( Desimone, MC; Rathmell, WK; Threadgill, DW, 2013)
"Azaserine was selected because it behaves as a direct-acting mutagen in two bacterial test systems and because tissue distribution studies showed concentration especially in kidney and pancreas."1.25Adenocarcinoma of the pancreas in azaserine-treated rats. ( Curphey, TJ; Longnecker, DS, 1975)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19902 (14.29)18.7374
1990's2 (14.29)18.2507
2000's4 (28.57)29.6817
2010's2 (14.29)24.3611
2020's4 (28.57)2.80

Authors

AuthorsStudies
Sun, H1
Zheng, J1
Xiao, J1
Yue, J1
Shi, Z1
Xuan, Z1
Chen, C1
Zhao, Y1
Tang, W1
Ye, S1
Li, J1
Deng, Q1
Zhang, L1
Zhu, F1
Shao, C1
Huo, FC1
Xie, M1
Zhu, ZM1
Zheng, JN1
Pei, DS1
Chesnel, F1
Jullion, E1
Delalande, O1
Couturier, A1
Alusse, A1
Le Goff, X1
Lenglet, M1
Gardie, B1
Abadie, C1
Arlot-Bonnemains, Y1
Arévalo, J1
Campoy, I1
Durán, M1
Nemours, S1
Areny, A1
Vall-Palomar, M1
Martínez, C1
Cantero-Recasens, G1
Meseguer, A1
Desimone, MC1
Rathmell, WK1
Threadgill, DW1
Kourtidis, A1
Yanagisawa, M1
Huveldt, D1
Copland, JA1
Anastasiadis, PZ1
Inukai, N1
Yamaguchi, Y1
Kuraoka, I1
Yamada, T1
Kamijo, S1
Kato, J1
Tanaka, K1
Handa, H1
Tremolada, L1
Magni, F1
Valsecchi, C1
Sarto, C1
Mocarelli, P1
Perego, R1
Cordani, N1
Favini, P1
Galli Kienle, M1
Sanchez, JC1
Hochstrasser, DF1
Corthals, GL1
Bianchi, F1
Galizia, E1
Porfiri, E1
Belvederesi, L1
Catalani, R1
Loretelli, C1
Bracci, R1
Bearzi, I1
Turchi, C1
Viel, A1
Cellerino, R1
Hiasa, Y1
Enoki, N1
Kitahori, Y1
Konishi, N1
Shimoyama, T1
Chatterjee, S1
Newton, DL1
Rybak, SM1
Hori, K1
Saito, S1
Kubota, K1
Longnecker, DS1
Curphey, TJ1

Other Studies

14 other studies available for serine and Kidney Neoplasms

ArticleYear
TOPK/PBK is phosphorylated by ERK2 at serine 32, promotes tumorigenesis and is involved in sorafenib resistance in RCC.
    Cell death & disease, 2022, 05-11, Volume: 13, Issue:5

    Topics: Carcinoma, Renal Cell; Cell Transformation, Neoplastic; Humans; Kidney Neoplasms; Mitogen-Activated

2022
SHMT2 promotes the tumorigenesis of renal cell carcinoma by regulating the m6A modification of PPAT.
    Genomics, 2022, Volume: 114, Issue:4

    Topics: Amidophosphoribosyltransferase; Carbon; Carcinogenesis; Carcinoma, Renal Cell; Cell Proliferation; C

2022
Mutation of the proline P81 into a serine modifies the tumour suppressor function of the von Hippel-Lindau gene in the ccRCC.
    British journal of cancer, 2022, Volume: 127, Issue:11

    Topics: Carcinoma, Renal Cell; Humans; Kidney Neoplasms; Mutation, Missense; Proline; Serine; Von Hippel-Lin

2022
STAT3 phosphorylation at serine 727 activates specific genetic programs and promotes clear cell renal cell carcinoma (ccRCC) aggressiveness.
    Scientific reports, 2023, 11-09, Volume: 13, Issue:1

    Topics: Carcinoma, Renal Cell; Cell Line, Tumor; Humans; Kidney Neoplasms; Phosphorylation; Serine; STAT3 Tr

2023
Pleiotropic effects of the trichloroethylene-associated P81S VHL mutation on metabolism, apoptosis, and ATM-mediated DNA damage response.
    Journal of the National Cancer Institute, 2013, Sep-18, Volume: 105, Issue:18

    Topics: Animals; Apoptosis; Arginine; Ataxia Telangiectasia Mutated Proteins; Carcinoma, Renal Cell; Cell Cy

2013
Pro-Tumorigenic Phosphorylation of p120 Catenin in Renal and Breast Cancer.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Blotting, Western; Breast Neoplasms; Carcinoma, Renal Cell; Catenins; Cell Transformation, Neoplasti

2015
A novel hydrogen peroxide-induced phosphorylation and ubiquitination pathway leading to RNA polymerase II proteolysis.
    The Journal of biological chemistry, 2004, Feb-27, Volume: 279, Issue:9

    Topics: Cell Death; Cell Line, Transformed; DNA Damage; DNA Repair; Female; Fibroblasts; HeLa Cells; Humans;

2004
Characterization of heat shock protein 27 phosphorylation sites in renal cell carcinoma.
    Proteomics, 2005, Volume: 5, Issue:3

    Topics: Carcinoma, Renal Cell; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; Humans; Immunohistochemistry;

2005
A missense germline mutation in exon 7 of the MSH2 gene in a HNPCC family from center-Italy.
    Familial cancer, 2007, Volume: 6, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Arginine; Colorectal Neopla

2007
DL-Serine: promoting activity on renal tumorigenesis by N-ethyl-N-hydroxyethylnitrosamine in rats.
    Journal of the National Cancer Institute, 1984, Volume: 73, Issue:1

    Topics: Animals; Body Weight; Carcinogens; Diethylnitrosamine; Drug Synergism; Kidney; Kidney Neoplasms; Mal

1984
Regulation of synthesis of lactosylceramide in normal and tumor proximal tubular cells.
    Biochimica et biophysica acta, 1993, Apr-23, Volume: 1167, Issue:3

    Topics: Antigens, CD; Cholesterol Esters; Galactosyltransferases; Glucose; Glycosphingolipids; Humans; Iodin

1993
Unique recombinant human ribonuclease and inhibition of Kaposi's sarcoma cell growth.
    Journal of the National Cancer Institute, 1998, Dec-02, Volume: 90, Issue:23

    Topics: Antineoplastic Agents; Blotting, Western; Breast Neoplasms; DNA, Complementary; Eosinophil-Derived N

1998
A novel combretastatin A-4 derivative, AC7700, strongly stanches tumour blood flow and inhibits growth of tumours developing in various tissues and organs.
    British journal of cancer, 2002, May-20, Volume: 86, Issue:10

    Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma; Drug Screening Assays, Antitumor; Heart Neopl

2002
Adenocarcinoma of the pancreas in azaserine-treated rats.
    Cancer research, 1975, Volume: 35, Issue:8

    Topics: Adenocarcinoma; Adenoma; Animals; Azaserine; Dipeptides; Disease Models, Animal; Hyperplasia; Inject

1975