Page last updated: 2024-11-08

serine and Kidney Diseases

serine has been researched along with Kidney Diseases in 21 studies

Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.

Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.

Research Excerpts

ExcerptRelevanceReference
"Intra-body dynamics of D-serine have the potential to predict the origin of kidney diseases."8.02Intra-body dynamics of D-serine reflects the origin of kidney diseases. ( Hayashi, T; Hesaka, A; Ikeda, T; Isaka, Y; Iwata, Y; Kimura, T; Mita, M; Nakane, M; Okushima, H; Sugimori, E, 2021)
"d-Serine, a long-term undetected enantiomer of serine, is now showing its potential as a biomarker for kidney diseases."5.05Utility of d-serine monitoring in kidney disease. ( Hesaka, A; Isaka, Y; Kimura, T, 2020)
"Intra-body dynamics of D-serine have the potential to predict the origin of kidney diseases."4.02Intra-body dynamics of D-serine reflects the origin of kidney diseases. ( Hayashi, T; Hesaka, A; Ikeda, T; Isaka, Y; Iwata, Y; Kimura, T; Mita, M; Nakane, M; Okushima, H; Sugimori, E, 2021)
"D-Serine causes selective necrosis to the straight portion of the rat renal proximal tubules."3.73Sodium benzoate attenuates D-serine induced nephrotoxicity in the rat. ( Lock, EA; Williams, RE, 2005)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19904 (19.05)18.7374
1990's1 (4.76)18.2507
2000's7 (33.33)29.6817
2010's4 (19.05)24.3611
2020's5 (23.81)2.80

Authors

AuthorsStudies
Nyamsuren, G1
Rapp, G1
Dihazi, H1
Zeisberg, EM1
Tampe, D1
Tampe, B1
Zeisberg, M1
Katsumi, H1
Morishita, M1
Yamamoto, A1
Kimura, T3
Sakai, S1
Isaka, Y3
Suzuki, M2
Gonda, Y1
Yamada, M1
Vandebroek, AA1
Mita, M2
Hamase, K1
Yasui, M1
Sasabe, J2
Hesaka, A2
Okushima, H1
Iwata, Y1
Sugimori, E1
Ikeda, T1
Nakane, M1
Hayashi, T1
Okada, A1
Nangaku, M1
Jao, TM1
Maekawa, H1
Ishimono, Y1
Kawakami, T1
Inagi, R1
Fujikura, T1
Togawa, A1
Sun, Y1
Iwakura, T1
Yasuda, H1
Fujigaki, Y1
WACHSTEIN, M2
MEISEL, E1
BESEN, M1
TAPP, E1
CARROLL, R1
KOVACS, K1
Fehr, T1
Zimmermann, DR1
Wüthrich, RP1
Ammann, P1
Williams, RE1
Lock, EA1
Cheong, HI1
Lee, JW1
Zheng, SH1
Lee, JH1
Kang, JH1
Kang, HG1
Ha, IS1
Lee, SJ1
Choi, Y1
Orozco-Ibarra, M1
Medina-Campos, ON1
Sánchez-González, DJ1
Martínez-Martínez, CM1
Floriano-Sánchez, E1
Santamaría, A1
Ramirez, V1
Bobadilla, NA1
Pedraza-Chaverri, J1
Krug, AW1
Völker, K1
Dantzler, WH1
Silbernagl, S1
Imai, K1
Fukushima, T1
Santa, T1
Homma, H1
Huang, Y1
Sakai, K1
Kato, M1
Fowler, B1
Rankin, GO1
Hong, SK1
Anestis, DK1
Henderson, TT1
Ball, JG1
Valentovic, MA1
Brown, PI1
Kennedy, A1
Saluga, PG1

Reviews

6 reviews available for serine and Kidney Diseases

ArticleYear
[Development of Serine Modification-based Kidney-targeted Drug Delivery System].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2023, Volume: 143, Issue:2

    Topics: Dendrimers; Drug Carriers; Drug Delivery Systems; Humans; Kidney; Kidney Diseases; Serine

2023
D-Serine as a sensor and effector of the kidney.
    Clinical and experimental nephrology, 2023, Volume: 27, Issue:11

    Topics: Biomarkers; Creatinine; Glomerular Filtration Rate; Humans; Kidney; Kidney Diseases; Serine

2023
Utility of d-serine monitoring in kidney disease.
    Biochimica et biophysica acta. Proteins and proteomics, 2020, Volume: 1868, Issue:9

    Topics: Acute Kidney Injury; Biomarkers; Clinical Decision-Making; Glomerular Filtration Rate; Humans; Kidne

2020
Distinctive Roles of D-Amino Acids in the Homochiral World: Chirality of Amino Acids Modulates Mammalian Physiology and Pathology.
    The Keio journal of medicine, 2019, Mar-25, Volume: 68, Issue:1

    Topics: Amino Acids; Animals; Archaea; Bacteria; D-Aspartic Acid; Endocrine System; Humans; Immunity, Innate

2019
Distribution of free D-amino acids in tissues and body fluids of vertebrates.
    Enantiomer, 1997, Volume: 2, Issue:3-4

    Topics: Alanine; Animals; Aspartic Acid; Humans; Kidney Diseases; Receptors, N-Methyl-D-Aspartate; Serine; S

1997
The folate cycle and disease in humans.
    Kidney international. Supplement, 2001, Volume: 78

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; 5,10-Methylenetetrahydrofolate Reductase

2001

Other Studies

15 other studies available for serine and Kidney Diseases

ArticleYear
PP2A phosphatase inhibition is anti-fibrotic through Ser77 phosphorylation-mediated ARNT/ARNT homodimer formation.
    Scientific reports, 2021, 12-15, Volume: 11, Issue:1

    Topics: Amino Acid Sequence; Animals; Aryl Hydrocarbon Receptor Nuclear Translocator; Biomarkers; Disease Mo

2021
Serum D-serine accumulation after proximal renal tubular damage involves neutral amino acid transporter Asc-1.
    Scientific reports, 2019, 11-13, Volume: 9, Issue:1

    Topics: Amino Acid Transport System y+; Animals; Antineoplastic Agents; Cisplatin; D-Amino-Acid Oxidase; Kid

2019
Intra-body dynamics of D-serine reflects the origin of kidney diseases.
    Clinical and experimental nephrology, 2021, Volume: 25, Issue:8

    Topics: Adult; Aged; Female; Humans; Kidney Diseases; Male; Middle Aged; Prospective Studies; Renal Insuffic

2021
D-serine, a novel uremic toxin, induces senescence in human renal tubular cells via GCN2 activation.
    Scientific reports, 2017, 09-11, Volume: 7, Issue:1

    Topics: Aging; Apoptosis; Cell Cycle Checkpoints; Cells, Cultured; Epithelial Cells; Humans; Kidney Diseases

2017
Dephosphorylated Ser985 of c-Met is associated with acquired resistance to rechallenge injury in rats that had recovered from uranyl acetate-induced subclinical renal damage.
    Clinical and experimental nephrology, 2013, Volume: 17, Issue:4

    Topics: Animals; Disease Resistance; Hepatocyte Growth Factor; Kidney Diseases; Kidney Tubules, Proximal; Ma

2013
A comparative study of enzymatic staining reactions in the rat kidney with necrobiosis induced by ischemia and nephrotoxic agents (mercuhydrin and DL-serine).
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1957, Volume: 5, Issue:3

    Topics: Animals; Kidney; Kidney Diseases; Necrobiotic Disorders; Organometallic Compounds; Purines; Rats; Se

1957
ELECTRON MICROSCOPY OF RENAL COAGULATIVE NECROSIS DUE TO DL-SERINE, WITH SPECIAL REFERENCE TO MITOCHONDRIAL PYKNOSIS.
    The American journal of pathology, 1964, Volume: 44

    Topics: Electrons; Injections, Intravenous; Kidney Diseases; Microscopy; Microscopy, Electron; Mitochondria;

1964
TETRACYCLINE FLUORESCENCE IN EXPERIMENTAL RENAL LESIONS.
    Archives of pathology, 1965, Volume: 79

    Topics: Ammonium Compounds; Chlorides; Fluorescence; Heparin Antagonists; Ischemia; Kidney; Kidney Diseases;

1965
A young renal transplant recipient with unexplained resting sinus tachycardia, hypertension and beta-blocker resistance.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2004, Volume: 19, Issue:6

    Topics: Adult; Arginine; Glycine; Homozygote; Humans; Hypertension; Kidney Diseases; Kidney Transplantation;

2004
Sodium benzoate attenuates D-serine induced nephrotoxicity in the rat.
    Toxicology, 2005, Feb-01, Volume: 207, Issue:1

    Topics: Animals; Creatinine; D-Amino-Acid Oxidase; Disease Models, Animal; Dose-Response Relationship, Drug;

2005
Phenotype and genotype of Dent's disease in three Korean boys.
    Pediatric nephrology (Berlin, Germany), 2005, Volume: 20, Issue:4

    Topics: Arginine; Asian People; Child; Child, Preschool; Chloride Channels; Codon, Nonsense; Diuretics; Furo

2005
Evaluation of oxidative stress in D-serine induced nephrotoxicity.
    Toxicology, 2007, Jan-05, Volume: 229, Issue:1-2

    Topics: Acetylglucosaminidase; Amitrole; Animals; Antioxidants; Blotting, Western; Catalase; Cell Adhesion M

2007
Why is D-serine nephrotoxic and alpha-aminoisobutyric acid protective?
    American journal of physiology. Renal physiology, 2007, Volume: 293, Issue:1

    Topics: Amino Acids; Aminoisobutyric Acids; Animals; D-Amino-Acid Oxidase; Dose-Response Relationship, Drug;

2007
Effect of three n-acetylamino acids on N-(3,5-dichlorophenyl)succinimide (NDPS) and ndps metabolite nephrotoxicity in Fischer 344 rats.
    Journal of toxicology and environmental health. Part A, 2002, Apr-12, Volume: 65, Issue:7

    Topics: Acetylcysteine; Alanine; Amino Acids; Animals; Fungicides, Industrial; Injections, Intraperitoneal;

2002
Urinary cytology in experimental toxic renal injury.
    Annals of the rheumatic diseases, 1970, Volume: 29, Issue:5

    Topics: Acute Kidney Injury; Animals; Aspirin; Azirines; Chromates; Eosinophils; Histocytochemistry; Kidney

1970