serine has been researched along with Invasiveness, Neoplasm in 52 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Imaging of breast cancer cell lines revealed that WFA induces perinuclear vimentin accumulation followed by rapid vimentin depolymerization." | 5.37 | Withaferin A inhibits breast cancer invasion and metastasis at sub-cytotoxic doses by inducing vimentin disassembly and serine 56 phosphorylation. ( Bender, L; Ganesh, T; Garcia, A; Harvey, RD; Kline, E; Liu, Y; Marcus, AI; Patel, P; Thaiparambil, JT; Tighiouart, M; Vertino, PM, 2011) |
| "Imaging of breast cancer cell lines revealed that WFA induces perinuclear vimentin accumulation followed by rapid vimentin depolymerization." | 1.37 | Withaferin A inhibits breast cancer invasion and metastasis at sub-cytotoxic doses by inducing vimentin disassembly and serine 56 phosphorylation. ( Bender, L; Ganesh, T; Garcia, A; Harvey, RD; Kline, E; Liu, Y; Marcus, AI; Patel, P; Thaiparambil, JT; Tighiouart, M; Vertino, PM, 2011) |
| "During squamous cell carcinoma (SCC) invasion, there is a reduction in the number of HDs, which may facilitate dissemination." | 1.37 | Role of β4 integrin phosphorylation in human invasive squamous cell carcinoma: regulation of hemidesmosome stability modulates cell migration. ( Germain, E; Kashyap, T; Lyle, S; Rabinovitz, I; Roche, M, 2011) |
| "Overexpression of Pak1 increased colorectal cancer cell motility and invasion, whereas down-regulation of Pak1 expression or activity reduced colorectal cancer cell migration and invasion." | 1.36 | P21-activated protein kinase 1 induces colorectal cancer metastasis involving ERK activation and phosphorylation of FAK at Ser-910. ( Chen, XH; Feng, B; Li, LH; Liu, BY; Lu, AG; Luo, Q; Su, LP; Wang, ML; Ye, Q; Zheng, MH, 2010) |
| "The management of locally advanced prostate cancer is difficult because the cancer often becomes hormone insensitive and unresponsive to current chemotherapeutic agents." | 1.34 | Protein kinase Cepsilon interacts with signal transducers and activators of transcription 3 (Stat3), phosphorylates Stat3Ser727, and regulates its constitutive activation in prostate cancer. ( Aziz, MH; Church, DR; Dreckschmidt, NE; Manoharan, HT; Oberley, TD; Verma, AK; Wilding, G; Zhong, W, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (3.85) | 18.2507 |
| 2000's | 14 (26.92) | 29.6817 |
| 2010's | 34 (65.38) | 24.3611 |
| 2020's | 2 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Park, SM | 1 |
| Seo, EH | 1 |
| Bae, DH | 1 |
| Kim, SS | 1 |
| Kim, J | 1 |
| Lin, W | 1 |
| Kim, KH | 1 |
| Park, JB | 1 |
| Kim, YS | 1 |
| Yin, J | 1 |
| Kim, SY | 1 |
| Volz, C | 1 |
| Breid, S | 1 |
| Selenz, C | 1 |
| Zaplatina, A | 1 |
| Golfmann, K | 1 |
| Meder, L | 1 |
| Dietlein, F | 1 |
| Borchmann, S | 1 |
| Chatterjee, S | 1 |
| Siobal, M | 1 |
| Schöttle, J | 1 |
| Florin, A | 1 |
| Koker, M | 1 |
| Nill, M | 1 |
| Ozretić, L | 1 |
| Uhlenbrock, N | 1 |
| Smith, S | 1 |
| Büttner, R | 1 |
| Miao, H | 1 |
| Wang, B | 1 |
| Reinhardt, HC | 1 |
| Rauh, D | 1 |
| Hallek, M | 1 |
| Acker-Palmer, A | 1 |
| Heukamp, LC | 1 |
| Ullrich, RT | 1 |
| Machado, RAC | 1 |
| Stojevski, D | 1 |
| De Landtsheer, S | 1 |
| Lucarelli, P | 1 |
| Baron, A | 1 |
| Sauter, T | 1 |
| Schaffner-Reckinger, E | 1 |
| Li, LY | 1 |
| Xie, YH | 1 |
| Xie, YM | 1 |
| Liao, LD | 1 |
| Xu, XE | 1 |
| Zhang, Q | 1 |
| Zeng, FM | 1 |
| Tao, LH | 1 |
| Xie, WM | 1 |
| Xie, JJ | 1 |
| Xu, LY | 1 |
| Li, EM | 1 |
| Zeng, S | 1 |
| Xie, X | 1 |
| Xiao, YF | 1 |
| Tang, B | 1 |
| Hu, CJ | 1 |
| Wang, SM | 1 |
| Wu, YY | 1 |
| Dong, H | 1 |
| Li, BS | 1 |
| Yang, SM | 1 |
| Liu, T | 1 |
| Zhao, Y | 1 |
| Wang, L | 2 |
| Jia, H | 1 |
| Cui, D | 1 |
| Si, Y | 1 |
| Wang, H | 1 |
| Xue, H | 1 |
| Brix, DM | 1 |
| Tvingsholm, SA | 1 |
| Hansen, MB | 1 |
| Clemmensen, KB | 1 |
| Ohman, T | 1 |
| Siino, V | 1 |
| Lambrughi, M | 1 |
| Hansen, K | 1 |
| Puustinen, P | 1 |
| Gromova, I | 1 |
| James, P | 1 |
| Papaleo, E | 1 |
| Varjosalo, M | 1 |
| Moreira, J | 1 |
| Jäättelä, M | 1 |
| Kallunki, T | 1 |
| Yin, L | 1 |
| Zeng, Y | 1 |
| Xiao, Y | 1 |
| Chen, Y | 1 |
| Shen, H | 1 |
| Dong, J | 1 |
| Zaoui, K | 1 |
| Boudhraa, Z | 1 |
| Khalifé, P | 1 |
| Carmona, E | 1 |
| Provencher, D | 1 |
| Mes-Masson, AM | 1 |
| Zhuo, DX | 1 |
| Zhang, XW | 1 |
| Jin, B | 1 |
| Zhang, Z | 1 |
| Xie, BS | 1 |
| Wu, CL | 1 |
| Gong, K | 1 |
| Mao, ZB | 1 |
| Boohaker, RJ | 1 |
| Cui, X | 1 |
| Stackhouse, M | 1 |
| Xu, B | 1 |
| Guo, Q | 1 |
| Su, N | 1 |
| Zhang, J | 2 |
| Li, X | 2 |
| Miao, Z | 1 |
| Wang, G | 1 |
| Cheng, M | 1 |
| Xu, H | 1 |
| Cao, L | 1 |
| Li, F | 1 |
| Fagan-Solis, KD | 1 |
| Pentecost, BT | 1 |
| Gozgit, JM | 1 |
| Bentley, BA | 1 |
| Marconi, SM | 1 |
| Otis, CN | 1 |
| Anderton, DL | 1 |
| Schneider, SS | 1 |
| Arcaro, KF | 1 |
| Iyengar, AS | 1 |
| Miller, PJ | 1 |
| Loupe, JM | 1 |
| Hollenbach, AD | 1 |
| Li, Z | 2 |
| Park, HR | 1 |
| Shi, Z | 1 |
| Pham, CD | 1 |
| Du, Y | 1 |
| Khuri, FR | 1 |
| Zhang, Y | 1 |
| Han, Q | 1 |
| Fu, H | 1 |
| Thakur, N | 1 |
| Gudey, SK | 1 |
| Marcusson, A | 1 |
| Fu, JY | 1 |
| Bergh, A | 1 |
| Heldin, CH | 1 |
| Landström, M | 1 |
| Li, C | 1 |
| Zhou, X | 1 |
| Chen, J | 1 |
| Lu, Y | 2 |
| Sun, Q | 1 |
| Tao, D | 1 |
| Hu, W | 1 |
| Zheng, X | 1 |
| Bian, S | 1 |
| Liu, Y | 3 |
| Ma, Y | 1 |
| Zhang, N | 1 |
| Chen, X | 1 |
| Döppler, H | 1 |
| Bastea, L | 1 |
| Borges, S | 1 |
| Geiger, X | 1 |
| Storz, P | 1 |
| Yoon, S | 1 |
| Kim, JG | 1 |
| Seo, AN | 1 |
| Park, SY | 1 |
| Kim, HJ | 1 |
| Park, JS | 1 |
| Choi, GS | 1 |
| Jeong, JY | 1 |
| Jun, do Y | 1 |
| Yoon, GS | 1 |
| Kang, BW | 1 |
| Sun, T | 1 |
| Fu, J | 2 |
| Shen, T | 1 |
| Lin, X | 1 |
| Liao, L | 2 |
| Feng, XH | 1 |
| Xu, J | 2 |
| Kuang, XY | 1 |
| Jiang, HS | 1 |
| Li, K | 1 |
| Zheng, YZ | 1 |
| Liu, YR | 1 |
| Qiao, F | 1 |
| Li, S | 1 |
| Hu, X | 1 |
| Shao, ZM | 1 |
| Phannasil, P | 1 |
| Ansari, IH | 1 |
| El Azzouny, M | 1 |
| Longacre, MJ | 1 |
| Rattanapornsompong, K | 1 |
| Burant, CF | 1 |
| MacDonald, MJ | 1 |
| Jitrapakdee, S | 1 |
| Sakurai, H | 1 |
| Ravid, D | 1 |
| Chuderland, D | 1 |
| Landsman, L | 1 |
| Lavie, Y | 1 |
| Reich, R | 1 |
| Liscovitch, M | 1 |
| Kang, HJ | 1 |
| Lee, H | 1 |
| Choi, HJ | 1 |
| Youn, JH | 1 |
| Shin, JS | 1 |
| Ahn, YH | 1 |
| Yoo, JS | 1 |
| Paik, YK | 1 |
| Kim, H | 1 |
| Gulati, N | 1 |
| Karsy, M | 1 |
| Albert, L | 1 |
| Murali, R | 1 |
| Jhanwar-Uniyal, M | 1 |
| Chin, YR | 1 |
| Toker, A | 1 |
| Wang, Z | 1 |
| Trope, CG | 1 |
| Flørenes, VA | 1 |
| Suo, Z | 1 |
| Nesland, JM | 1 |
| Holm, R | 1 |
| Li, LH | 1 |
| Zheng, MH | 1 |
| Luo, Q | 1 |
| Ye, Q | 1 |
| Feng, B | 1 |
| Lu, AG | 1 |
| Wang, ML | 1 |
| Chen, XH | 1 |
| Su, LP | 1 |
| Liu, BY | 1 |
| Wang, P | 1 |
| Wu, F | 1 |
| McMullen, T | 1 |
| Young, LC | 1 |
| Ingham, RJ | 1 |
| Li, L | 1 |
| Lai, R | 1 |
| Zhang, PX | 1 |
| Wang, Y | 1 |
| Jiang, GY | 1 |
| Li, QC | 1 |
| Wang, EH | 1 |
| Hong, J | 1 |
| Zhou, J | 1 |
| He, T | 1 |
| Qin, J | 1 |
| Lin, RZ | 1 |
| Wang, TP | 1 |
| Hung, RJ | 1 |
| Chuang, YJ | 1 |
| Chien, CC | 1 |
| Chang, HY | 1 |
| Thaiparambil, JT | 1 |
| Bender, L | 1 |
| Ganesh, T | 1 |
| Kline, E | 1 |
| Patel, P | 1 |
| Tighiouart, M | 1 |
| Vertino, PM | 1 |
| Harvey, RD | 1 |
| Garcia, A | 1 |
| Marcus, AI | 1 |
| Kashyap, T | 1 |
| Germain, E | 1 |
| Roche, M | 1 |
| Lyle, S | 1 |
| Rabinovitz, I | 1 |
| McParland, V | 1 |
| Varsano, G | 1 |
| Thornton, J | 1 |
| Baby, J | 1 |
| Aravind, A | 1 |
| Meyer, C | 1 |
| Pavic, K | 1 |
| Rios, P | 1 |
| Köhn, M | 1 |
| Donini, CF | 1 |
| Di Zazzo, E | 1 |
| Zuchegna, C | 1 |
| Di Domenico, M | 1 |
| D'Inzeo, S | 1 |
| Nicolussi, A | 1 |
| Avvedimento, EV | 1 |
| Coppa, A | 1 |
| Porcellini, A | 1 |
| Rettig, M | 1 |
| Trinidad, K | 1 |
| Pezeshkpour, G | 1 |
| Frost, P | 1 |
| Sharma, S | 1 |
| Moatamed, F | 1 |
| Tamanoi, F | 1 |
| Mortazavi, F | 1 |
| Rieger-Christ, KM | 1 |
| Lee, P | 1 |
| Zagha, R | 1 |
| Kosakowski, M | 1 |
| Moinzadeh, A | 1 |
| Stoffel, J | 1 |
| Ben-Ze'ev, A | 1 |
| Libertino, JA | 1 |
| Summerhayes, IC | 1 |
| Murphy, LC | 1 |
| Niu, Y | 1 |
| Snell, L | 1 |
| Watson, P | 1 |
| Cardone, RA | 1 |
| Bagorda, A | 1 |
| Bellizzi, A | 1 |
| Busco, G | 1 |
| Guerra, L | 1 |
| Paradiso, A | 1 |
| Casavola, V | 1 |
| Zaccolo, M | 1 |
| Reshkin, SJ | 1 |
| Rosty, C | 1 |
| Aubriot, MH | 1 |
| Cappellen, D | 1 |
| Bourdin, J | 1 |
| Cartier, I | 1 |
| Thiery, JP | 1 |
| Sastre-Garau, X | 1 |
| Radvanyi, F | 1 |
| McDonough, WS | 1 |
| Tran, NL | 1 |
| Berens, ME | 1 |
| Koul, D | 1 |
| Shen, R | 1 |
| Bergh, S | 1 |
| de Groot, JF | 1 |
| Liu, TJ | 1 |
| Mills, GB | 1 |
| Yung, WK | 1 |
| Matsuzaki, K | 1 |
| Miller, SL | 1 |
| Antico, G | 1 |
| Raghunath, PN | 1 |
| Tomaszewski, JE | 1 |
| Clevenger, CV | 1 |
| Aziz, MH | 1 |
| Manoharan, HT | 1 |
| Church, DR | 1 |
| Dreckschmidt, NE | 1 |
| Zhong, W | 1 |
| Oberley, TD | 1 |
| Wilding, G | 1 |
| Verma, AK | 1 |
| Liu, R | 1 |
| Tian, B | 1 |
| Gearing, M | 1 |
| Hunter, S | 1 |
| Ye, K | 1 |
| Mao, Z | 1 |
| Rabbani, F | 1 |
| Richon, VM | 1 |
| Orlow, I | 1 |
| Lu, ML | 1 |
| Drobnjak, M | 1 |
| Dudas, M | 1 |
| Charytonowicz, E | 1 |
| Dalbagni, G | 1 |
| Cordon-Cardo, C | 1 |
| Huang, YT | 1 |
| Hwang, JJ | 1 |
| Lee, LT | 1 |
| Liebow, C | 1 |
| Lee, PP | 1 |
| Ke, FC | 1 |
| Lo, TB | 1 |
| Schally, AV | 1 |
| Lee, MT | 1 |
| Samuel, SK | 1 |
| Hurta, RA | 1 |
| Kondaiah, P | 1 |
| Khalil, N | 1 |
| Turley, EA | 1 |
| Wright, JA | 1 |
| Greenberg, AH | 1 |
2 reviews available for serine and Invasiveness, Neoplasm
| Article | Year |
|---|---|
Non-canonical Activation of Receptor Tyrosine Kinases in Cancer Progression.
Topics: Antineoplastic Agents; Cell Movement; Cell Proliferation; Disease Progression; Drug Resistance, Neop | 2017 |
Smad3 phosphoisoform-mediated signaling during sporadic human colorectal carcinogenesis.
Topics: Adenocarcinoma; Adenoma; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Colorec | 2006 |
50 other studies available for serine and Invasiveness, Neoplasm
| Article | Year |
|---|---|
Phosphoserine Phosphatase Promotes Lung Cancer Progression through the Dephosphorylation of IRS-1 and a Noncanonical L-Serine-Independent Pathway.
Topics: A549 Cells; Animals; Disease Progression; Humans; Insulin Receptor Substrate Proteins; Lung Neoplasm | 2019 |
Inhibition of Tumor VEGFR2 Induces Serine 897 EphA2-Dependent Tumor Cell Invasion and Metastasis in NSCLC.
Topics: Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Neoplasm Invasiveness; Neoplasm Metastasis; | 2020 |
L-plastin Ser5 phosphorylation is modulated by the PI3K/SGK pathway and promotes breast cancer cell invasiveness.
Topics: Breast Neoplasms; Cell Line; Cell Movement; Female; Humans; Membrane Glycoproteins; Microfilament Pr | 2021 |
Ezrin Ser66 phosphorylation regulates invasion and metastasis of esophageal squamous cell carcinoma cells by mediating filopodia formation.
Topics: Carcinogenesis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Cytos | 2017 |
Long noncoding RNA LINC00675 enhances phosphorylation of vimentin on Ser83 to suppress gastric cancer progression.
Topics: Adult; Aged; Animals; Cell Movement; Disease Progression; Female; Genes, Tumor Suppressor; Humans; M | 2018 |
[Effects of serine/threonine-protein kinase B-Raf-activated long-chain non-coding RNA on apoptosis and autophagy in thyroid carcinoma cells].
Topics: Apoptosis; Autophagy; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Neoplasm I | 2018 |
Release of transcriptional repression via ErbB2-induced, SUMO-directed phosphorylation of myeloid zinc finger-1 serine 27 activates lysosome redistribution and invasion.
Topics: Breast Neoplasms; CCCTC-Binding Factor; Cell Line, Tumor; Female; Humans; Kruppel-Like Transcription | 2019 |
Cyclin-dependent kinase 1-mediated phosphorylation of SET at serine 7 is essential for its oncogenic activity.
Topics: Carcinogenesis; CDC2 Protein Kinase; Cell Line, Tumor; Cell Movement; DNA-Binding Proteins; Gene Del | 2019 |
Ran promotes membrane targeting and stabilization of RhoA to orchestrate ovarian cancer cell invasion.
Topics: Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cell Membrane; Female; Gene Knockdown Techniques; H | 2019 |
CSTP1, a novel protein phosphatase, blocks cell cycle, promotes cell apoptosis, and suppresses tumor growth of bladder cancer by directly dephosphorylating Akt at Ser473 site.
Topics: Amino Acid Sequence; Animals; Apoptosis; Base Sequence; Calcineurin; Cell Cycle; Cell Division; DNA | 2013 |
ATM-mediated Snail Serine 100 phosphorylation regulates cellular radiosensitivity.
Topics: Ataxia Telangiectasia Mutated Proteins; Histones; Humans; Neoplasm Invasiveness; Neoplasms; Phosphor | 2013 |
PAK4 kinase-mediated SCG10 phosphorylation involved in gastric cancer metastasis.
Topics: Animals; cdc42 GTP-Binding Protein; Cell Line; Cell Line, Tumor; Cell Movement; Female; HEK293 Cells | 2014 |
SKP2 overexpression is associated with increased serine 10 phosphorylation of p27 (pSer10p27) in triple-negative breast cancer.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Biomarkers, Tumor; Cell Cycle; Cell Proliferation; Cycl | 2014 |
Phosphorylation of PAX3 contributes to melanoma phenotypes by affecting proliferation, invasion, and transformation.
Topics: Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Humans; Melanocytes; Melanoma | 2014 |
Pro-oncogenic function of HIP-55/Drebrin-like (DBNL) through Ser269/Thr291-phospho-sensor motifs.
Topics: 14-3-3 Proteins; Adenocarcinoma; Amino Acid Motifs; Animals; Apoptosis; Blotting, Western; Cell Line | 2014 |
TGFβ-induced invasion of prostate cancer cells is promoted by c-Jun-dependent transcriptional activation of Snail1.
Topics: Breast Neoplasms; Cell Line, Tumor; Female; Humans; JNK Mitogen-Activated Protein Kinases; Male; MAP | 2014 |
PIWIL1 destabilizes microtubule by suppressing phosphorylation at Ser16 and RLIM-mediated degradation of Stathmin1.
Topics: Argonaute Proteins; Blotting, Western; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Prolife | 2015 |
Potential role of O-GlcNAcylation and involvement of PI3K/Akt1 pathway in the expression of oncogenic phenotypes of gastric cancer cells in vitro.
Topics: Acetylglucosamine; beta-N-Acetylhexosaminidases; Cell Line, Tumor; Cell Movement; Cell Proliferation | 2016 |
The phosphorylation status of VASP at serine 322 can be predictive for aggressiveness of invasive ductal carcinoma.
Topics: Breast Neoplasms; Carcinoma, Ductal; Cell Adhesion Molecules; Cell Line; Cell Line, Tumor; Cell Move | 2015 |
Clinical Implication of Serine Metabolism-Associated Enzymes in Colon Cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biom | 2015 |
The Small C-terminal Domain Phosphatase 1 Inhibits Cancer Cell Migration and Invasion by Dephosphorylating Ser(P)68-Twist1 to Accelerate Twist1 Protein Degradation.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Movement; Epithelial-Mesenchymal Transition; Humans; Mitoge | 2016 |
The phosphorylation-specific association of STMN1 with GRP78 promotes breast cancer metastasis.
Topics: Animals; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Decision Support Tech | 2016 |
Mass spectrometry analysis shows the biosynthetic pathways supported by pyruvate carboxylase in highly invasive breast cancer cells.
Topics: Acetyl Coenzyme A; Aspartic Acid; Biosynthetic Pathways; Breast Neoplasms; Cell Line, Tumor; Cell Pr | 2017 |
Filamin A is a novel caveolin-1-dependent target in IGF-I-stimulated cancer cell migration.
Topics: Amino Acid Sequence; Breast Neoplasms; Caveolae; Caveolin 1; Cell Line, Tumor; Cell Membrane; Cell M | 2008 |
Non-histone nuclear factor HMGB1 is phosphorylated and secreted in colon cancers.
Topics: Adenocarcinoma; Biomarkers, Tumor; Cell Line, Tumor; Cell Movement; Cell Nucleus; Colonic Neoplasms; | 2009 |
Involvement of mTORC1 and mTORC2 in regulation of glioblastoma multiforme growth and motility.
Topics: Active Transport, Cell Nucleus; Adaptor Proteins, Signal Transducing; Antibiotics, Antineoplastic; C | 2009 |
The actin-bundling protein palladin is an Akt1-specific substrate that regulates breast cancer cell migration.
Topics: Actins; Breast Neoplasms; Cell Movement; Cell Shape; Cytoskeletal Proteins; Cytoskeleton; Enzyme Act | 2010 |
Overexpression of CDC25B, CDC25C and phospho-CDC25C (Ser216) in vulvar squamous cell carcinomas are associated with malignant features and aggressive cancer phenotypes.
Topics: Adult; Aged; Aged, 80 and over; Antibody Specificity; Blotting, Western; Carcinoma, Squamous Cell; c | 2010 |
P21-activated protein kinase 1 induces colorectal cancer metastasis involving ERK activation and phosphorylation of FAK at Ser-910.
Topics: Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Enzyme Activation; Female | 2010 |
Serine phosphorylation of NPM-ALK, which is dependent on the auto-activation of the kinase activation loop, contributes to its oncogenic potential.
Topics: Cell Line, Tumor; Enzyme Activation; Humans; Neoplasm Invasiveness; Neoplasms; Phosphorylation; Prot | 2011 |
p120-catenin isoform 3 regulates subcellular localization of Kaiso and promotes invasion in lung cancer cells via a phosphorylation-dependent mechanism.
Topics: Active Transport, Cell Nucleus; Amino Acid Substitution; Animals; Catenins; Cell Line, Tumor; Delta | 2011 |
Phosphorylation of serine 68 of Twist1 by MAPKs stabilizes Twist1 protein and promotes breast cancer cell invasiveness.
Topics: Breast Neoplasms; Cell Line, Tumor; Epithelial-Mesenchymal Transition; Female; HEK293 Cells; Humans; | 2011 |
Tumor-induced endothelial cell apoptosis: roles of NAD(P)H oxidase-derived reactive oxygen species.
Topics: Animals; Antioxidants; Apoptosis; Calcium; Cell Communication; Cell Movement; Coculture Techniques; | 2011 |
Withaferin A inhibits breast cancer invasion and metastasis at sub-cytotoxic doses by inducing vimentin disassembly and serine 56 phosphorylation.
Topics: Animals; Antineoplastic Agents; Blotting, Western; Breast Neoplasms; Cell Differentiation; Cell Line | 2011 |
Role of β4 integrin phosphorylation in human invasive squamous cell carcinoma: regulation of hemidesmosome stability modulates cell migration.
Topics: Basement Membrane; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Drug Stability; Hemide | 2011 |
The metastasis-promoting phosphatase PRL-3 shows activity toward phosphoinositides.
Topics: Amino Acid Sequence; Catalysis; Cell Movement; Cysteine; Enzyme Activation; Genetic Variation; HEK29 | 2011 |
The p85α regulatory subunit of PI3K mediates cAMP-PKA and retinoic acid biological effects on MCF7 cell growth and migration.
Topics: Alanine; Animals; Antineoplastic Agents; Aspartic Acid; Breast Neoplasms; Cattle; Cell Cycle Checkpo | 2012 |
PAK1 kinase promotes cell motility and invasiveness through CRK-II serine phosphorylation in non-small cell lung cancer cells.
Topics: Carcinoma, Non-Small-Cell Lung; Catenins; Cell Line, Tumor; Cell Movement; Delta Catenin; Gene Expre | 2012 |
Novel expression of N-cadherin elicits in vitro bladder cell invasion via the Akt signaling pathway.
Topics: Blotting, Western; Cadherins; Carcinoma; Cell Line, Tumor; Chromones; Clone Cells; Collagen; Drug Co | 2004 |
Phospho-serine-118 estrogen receptor-alpha expression is associated with better disease outcome in women treated with tamoxifen.
Topics: Antineoplastic Agents, Hormonal; Breast Neoplasms; Disease-Free Survival; Estrogen Receptor alpha; F | 2004 |
Protein kinase A gating of a pseudopodial-located RhoA/ROCK/p38/NHE1 signal module regulates invasion in breast cancer cell lines.
Topics: Breast Neoplasms; Cation Transport Proteins; Cell Line, Tumor; Collagen; Culture Media, Serum-Free; | 2005 |
Clinical and biological characteristics of cervical neoplasias with FGFR3 mutation.
Topics: Adult; Age Distribution; Aged; Aged, 80 and over; Female; Gene Expression Regulation, Neoplastic; Hu | 2005 |
Regulation of glioma cell migration by serine-phosphorylated P311.
Topics: Amino Acid Sequence; Cell Line, Tumor; Cell Movement; Contractile Proteins; Filamins; Glioma; Humans | 2005 |
Targeting integrin-linked kinase inhibits Akt signaling pathways and decreases tumor progression of human glioblastoma.
Topics: Blotting, Western; Cell Cycle; Cell Division; Cell Line, Tumor; Cell Movement; Cell Proliferation; C | 2005 |
Nek3 kinase regulates prolactin-mediated cytoskeletal reorganization and motility of breast cancer cells.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Movement; CHO Cells; Cricetinae; Cricetulus; Cytos | 2007 |
Protein kinase Cepsilon interacts with signal transducers and activators of transcription 3 (Stat3), phosphorylates Stat3Ser727, and regulates its constitutive activation in prostate cancer.
Topics: Animals; Cell Line, Tumor; Cytokines; Humans; Male; Mice; Mice, Inbred C57BL; Neoplasm Invasiveness; | 2007 |
Cdk5-mediated regulation of the PIKE-A-Akt pathway and glioblastoma cell invasion.
Topics: Active Transport, Cell Nucleus; Cell Line, Tumor; Cell Movement; Central Nervous System Neoplasms; C | 2008 |
Prognostic significance of transcription factor E2F-1 in bladder cancer: genotypic and phenotypic characterization.
Topics: Carcinoma; Carrier Proteins; Cell Cycle Proteins; DNA-Binding Proteins; E2F Transcription Factors; E | 1999 |
Inhibitory effects of a luteinizing hormone-releasing hormone agonist on basal and epidermal growth factor-induced cell proliferation and metastasis-associated properties in human epidermoid carcinoma A431 cells.
Topics: Antineoplastic Agents, Hormonal; Carcinoma, Squamous Cell; Caspases; Cell Division; DNA Fragmentatio | 2002 |
Autocrine induction of tumor protease production and invasion by a metallothionein-regulated TGF-beta 1 (Ser223, 225).
Topics: Amino Acid Sequence; Animals; Cathepsin L; Cathepsins; Cell Line; Cell Movement; Enzyme Precursors; | 1992 |