Page last updated: 2024-11-08

serine and Insulinoma

serine has been researched along with Insulinoma in 4 studies

Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.

Insulinoma: A benign tumor of the PANCREATIC BETA CELLS. Insulinoma secretes excess INSULIN resulting in HYPOGLYCEMIA.

Research Excerpts

ExcerptRelevanceReference
" We investigated the effects of O-GlcNAc modification on actin reorganization and morphology of rat insulinoma INS-1 cells after glucosamine (GlcN) treatment."7.76Glucosamine treatment-mediated O-GlcNAc modification of paxillin depends on adhesion state of rat insulinoma INS-1 cells. ( Jung, O; Kang, M; Kim, H; Kim, HJ; Kim, SH; Kwak, TK; Lee, JW; Lee, SA; Park, JM, 2010)
" We investigated the effects of O-GlcNAc modification on actin reorganization and morphology of rat insulinoma INS-1 cells after glucosamine (GlcN) treatment."3.76Glucosamine treatment-mediated O-GlcNAc modification of paxillin depends on adhesion state of rat insulinoma INS-1 cells. ( Jung, O; Kang, M; Kim, H; Kim, HJ; Kim, SH; Kwak, TK; Lee, JW; Lee, SA; Park, JM, 2010)
" Finally, glucagon-stimulated insulin secretion by RIN cells expressing the mutant receptor was decreased such that the dose-response curve was shifted to the right in comparison to that obtained with cells expressing the wild type receptor."1.29The Gly40Ser mutation in the human glucagon receptor gene associated with NIDDM results in a receptor with reduced sensitivity to glucagon. ( Abrahamsen, N; Froguel, P; Hager, J; Hansen, LH; Jelinek, L; Kindsvogel, W; Nishimura, E, 1996)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kwak, TK1
Kim, H1
Jung, O1
Lee, SA1
Kang, M1
Kim, HJ1
Park, JM1
Kim, SH1
Lee, JW1
Shu, Y1
Liu, X1
Yang, Y1
Takahashi, M1
Gillis, KD1
Sjöholm, A1
Honkanen, RE1
Berggren, PO1
Hansen, LH1
Abrahamsen, N1
Hager, J1
Jelinek, L1
Kindsvogel, W1
Froguel, P1
Nishimura, E1

Other Studies

4 other studies available for serine and Insulinoma

ArticleYear
Glucosamine treatment-mediated O-GlcNAc modification of paxillin depends on adhesion state of rat insulinoma INS-1 cells.
    The Journal of biological chemistry, 2010, Nov-12, Volume: 285, Issue:46

    Topics: Acetylglucosamine; Actins; Animals; Blotting, Western; Cell Adhesion; Cell Line, Tumor; Diabetes Mel

2010
Phosphorylation of SNAP-25 at Ser187 mediates enhancement of exocytosis by a phorbol ester in INS-1 cells.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Jan-02, Volume: 28, Issue:1

    Topics: Animals; Botulinum Toxins, Type A; Calcium; Cattle; Cells, Cultured; Chromaffin Cells; Dose-Response

2008
Inhibition of serine/threonine protein phosphatases by secretagogues in insulin-secreting cells.
    Endocrinology, 1995, Volume: 136, Issue:8

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Arginine; Glutamine; Insulin; Insulin Secretion; Insuli

1995
The Gly40Ser mutation in the human glucagon receptor gene associated with NIDDM results in a receptor with reduced sensitivity to glucagon.
    Diabetes, 1996, Volume: 45, Issue:6

    Topics: Amino Acid Sequence; Animals; Cell Line; Cricetinae; Cyclic AMP; Diabetes Mellitus, Type 2; Exons; G

1996