serine has been researched along with Innate Inflammatory Response in 104 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Serine/Threonine phosphorylation of RIPK1 is known to suppress RIPK1 kinase-mediated cell death in the contexts of inflammation, infection and embryogenesis, however, regulation by tyrosine phosphorylation has not been reported." | 8.12 | Tyrosine phosphorylation regulates RIPK1 activity to limit cell death and inflammation. ( Lin, X; Tu, H; Xiong, W; Zhang, J; Zhao, X, 2022) |
| " Here, we studied extracellular serine and serine/glycine metabolism using human keratinocytes, human skin biopsies, and a mouse model of psoriasis-like disease." | 8.12 | Extracellular serine empowers epidermal proliferation and psoriasis-like symptoms. ( Albanesi, C; Annicchiarico-Petruzzelli, M; Belardo, A; Candi, E; Cappello, A; Cutruzzolà, F; Jia, W; Madonna, S; Mancini, M; Melino, G; Pallotta, S; Panatta, E; Paone, A; Rinaldo, S; Scarponi, C; Wang, L; Zolla, L; Zuccotti, A, 2022) |
| " After establishing FDL, l-serine treatment: 1) improved spatial learning, memory and cognitive ability in mice, and relieved anxiety for 4 weeks post-FDL induction; 2) reduced abnormally dephosphorylated neurofilament proteins, increased myelin basic protein, and preserved anatomic myelinated axons; 3) inhibited microglia activation and reduced the release of inflammatory factors; 4) promoted recruitment and proliferation of oligodendrocyte progenitor cells, and the efficiency of subsequent remyelination on day twenty-eight post-FDL induction." | 7.91 | Neuroprotective effect of l-serine against white matter demyelination by harnessing and modulating inflammation in mice. ( Ding, L; Gan, D; Gao, C; Jiang, Z; Luo, Q; Sun, Y; Wang, G; Xu, L; Zhang, N, 2019) |
| "In this study, we quantitated kaempferol in water extract from Cudrania tricuspidata leaves (CTL) and investigated its effects on endoplasmic reticulum (ER) stress-induced inflammation and insulin resistance in HepG2 cells." | 7.83 | Effect of Cudrania tricuspidata and Kaempferol in Endoplasmic Reticulum Stress-Induced Inflammation and Hepatic Insulin Resistance in HepG2 Cells. ( Jun, W; Kim, OK; Lee, J, 2016) |
| " This study evaluated the potential usefulness of supplementation of total parenteral nutrition with a cysteine, taurine, threonine, and serine mixture (SEAS), with or without glutamine, in an experimental model of turpentine-induced acute inflammation." | 7.72 | Efficiency of a cysteine-taurine-threonine-serine supplemented parenteral nutrition in an experimental model of acute inflammation. ( Bérard, MP; Chaïb, S; Cynober, L; De Bandt, JP; Neveux, N; Osowska, S, 2003) |
| "Although the involvement of chronic overnutrition, systemic inflammation, and insulin resistance in the development of NAFLD is well-established, however, the associations among these remain to be elucidated." | 5.91 | Diet-induced induction of hepatic serine/threonine kinase STK38 triggers proinflammation and hepatic lipid accumulation. ( Dehury, B; Dogra, S; Jaswal, K; Mondal, P; Rawat, P; Thakur, S, 2023) |
| "Depression is associated with immune dysregulation and the aberrant activity of the hypothalamic-pituitary-adrenal (HPA) axis." | 5.56 | Inhibition of JNK ameliorates depressive-like behaviors and reduces the activation of pro-inflammatory cytokines and the phosphorylation of glucocorticoid receptors at serine 246 induced by neuroinflammation. ( Li, Y; Lin, W; Tang, M; Wang, X; Zhang, J; Zhang, K; Zhao, Y, 2020) |
| "Mefenamic acid treatment provided significant protection against the elevation of lipid peroxidation, protein oxidation, levels of TNF-α, IL-1β and Bax." | 5.38 | Neuroprotection by mefenamic acid against D-serine: involvement of oxidative stress, inflammation and apoptosis. ( Armagan, G; Kanit, L; Turunc, E; Yalcin, A, 2012) |
| "Streptococcus pneumoniae is the major cause of community-acquired pneumonia and one of the most common causes of death by infectious disease in industrialized countries." | 5.32 | Streptococcus pneumoniae-induced p38 MAPK-dependent phosphorylation of RelA at the interleukin-8 promotor. ( Hammerschmidt, S; Hippenstiel, S; Hocke, AC; Hoffmann, E; Huber, S; Kracht, M; Moog, K; Opitz, B; Rosseau, S; Schmeck, B; Suttorp, N; van Laak, V; Zahlten, J; Zerrahn, J, 2004) |
| " Serine/Threonine phosphorylation of RIPK1 is known to suppress RIPK1 kinase-mediated cell death in the contexts of inflammation, infection and embryogenesis, however, regulation by tyrosine phosphorylation has not been reported." | 4.12 | Tyrosine phosphorylation regulates RIPK1 activity to limit cell death and inflammation. ( Lin, X; Tu, H; Xiong, W; Zhang, J; Zhao, X, 2022) |
| " Here, we studied extracellular serine and serine/glycine metabolism using human keratinocytes, human skin biopsies, and a mouse model of psoriasis-like disease." | 4.12 | Extracellular serine empowers epidermal proliferation and psoriasis-like symptoms. ( Albanesi, C; Annicchiarico-Petruzzelli, M; Belardo, A; Candi, E; Cappello, A; Cutruzzolà, F; Jia, W; Madonna, S; Mancini, M; Melino, G; Pallotta, S; Panatta, E; Paone, A; Rinaldo, S; Scarponi, C; Wang, L; Zolla, L; Zuccotti, A, 2022) |
| " After establishing FDL, l-serine treatment: 1) improved spatial learning, memory and cognitive ability in mice, and relieved anxiety for 4 weeks post-FDL induction; 2) reduced abnormally dephosphorylated neurofilament proteins, increased myelin basic protein, and preserved anatomic myelinated axons; 3) inhibited microglia activation and reduced the release of inflammatory factors; 4) promoted recruitment and proliferation of oligodendrocyte progenitor cells, and the efficiency of subsequent remyelination on day twenty-eight post-FDL induction." | 3.91 | Neuroprotective effect of l-serine against white matter demyelination by harnessing and modulating inflammation in mice. ( Ding, L; Gan, D; Gao, C; Jiang, Z; Luo, Q; Sun, Y; Wang, G; Xu, L; Zhang, N, 2019) |
| " Intraperitoneal injection of D-serine obviously limited the lipopolysaccharide-induced changes, including the impairment of learning and memory, the loss of NMDA receptor subunits, robust neuroinflammation, the levels of ROS stress and the decrease of p-CREB in the hippocampus of mice." | 3.85 | Sepsis-induced selective loss of NMDA receptors modulates hippocampal neuropathology in surviving septic mice. ( Ai, S; Le, Y; Ouyang, W; Tong, J; Wang, X; Zhang, S, 2017) |
| "In this study, we quantitated kaempferol in water extract from Cudrania tricuspidata leaves (CTL) and investigated its effects on endoplasmic reticulum (ER) stress-induced inflammation and insulin resistance in HepG2 cells." | 3.83 | Effect of Cudrania tricuspidata and Kaempferol in Endoplasmic Reticulum Stress-Induced Inflammation and Hepatic Insulin Resistance in HepG2 Cells. ( Jun, W; Kim, OK; Lee, J, 2016) |
| " The results showed that amygdalin and cinnamic acid inhibit serine phosphorylation of IRS-1 through targeting JNK serine kinase and enhance insulin sensitivity." | 3.81 | Cell lysis-free quantum dot multicolor cellular imaging-based mechanism study for TNF-α-induced insulin resistance. ( Kim, MJ; Rangasamy, S; Shim, Y; Song, JM, 2015) |
| " We find that these responses are mutually antagonistic with, on the one hand, heat shock factor 1 (HSF1) inhibition through the phosphorylation of inhibitory serine residues after inflammatory or mitogenic stimulus and, on the other hand, after stress, HSF1 directly repressing the promoters of genes that mediate acute inflammation and mitogenesis." | 3.73 | Regulatory interfaces between the stress protein response and other gene expression programs in the cell. ( Calderwood, SK, 2005) |
| " This study evaluated the potential usefulness of supplementation of total parenteral nutrition with a cysteine, taurine, threonine, and serine mixture (SEAS), with or without glutamine, in an experimental model of turpentine-induced acute inflammation." | 3.72 | Efficiency of a cysteine-taurine-threonine-serine supplemented parenteral nutrition in an experimental model of acute inflammation. ( Bérard, MP; Chaïb, S; Cynober, L; De Bandt, JP; Neveux, N; Osowska, S, 2003) |
| " We have recently proposed another mechanism for aldehyde generation at sites of inflammation that involves myeloperoxidase, a heme enzyme secreted by activated phagocytes." | 3.69 | Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to convert hydroxy-amino acids into glycolaldehyde, 2-hydroxypropanal, and acrolein. A mechanism for the generation of highly reactive alpha-hydroxy and alpha,beta-unsaturated ( Anderson, MM; Hazen, SL; Heinecke, JW; Hsu, FF, 1997) |
| "Diabetes mellitus is a metabolic disease that is characterized by chronic hyperglycemia due to a variety of etiological factors." | 3.01 | RIPK1 and RIPK3 inhibitors: potential weapons against inflammation to treat diabetic complications. ( Chen, P; Chu, Y; Dai, Y; Ke, D; Li, L; Liu, J; Sun, X; Zhang, Z, 2023) |
| "SERPINA3 seems to have cancer- and compartment-specific biological functions, acting either as a tumour promoter or suppressor in different cancers." | 2.82 | Unfolding the cascade of SERPINA3: Inflammation to cancer. ( Asha Nair, S; Soman, A, 2022) |
| "Inflammation is detrimental to β-cell function and survival, moreover, both apoptosis and necrosis have been implicated as mechanisms of β-cell loss in T1D." | 1.91 | Inhibition of RIPK1 kinase does not affect diabetes development: β-Cells survive RIPK1 activation. ( Arroba, EN; Bertrand, MJ; Cardozo, AK; Franchimont, M; Gilglioni, EH; Gurzov, EN; Takiishi, T; Xiao, P, 2023) |
| "Although the involvement of chronic overnutrition, systemic inflammation, and insulin resistance in the development of NAFLD is well-established, however, the associations among these remain to be elucidated." | 1.91 | Diet-induced induction of hepatic serine/threonine kinase STK38 triggers proinflammation and hepatic lipid accumulation. ( Dehury, B; Dogra, S; Jaswal, K; Mondal, P; Rawat, P; Thakur, S, 2023) |
| "Depression is associated with immune dysregulation and the aberrant activity of the hypothalamic-pituitary-adrenal (HPA) axis." | 1.56 | Inhibition of JNK ameliorates depressive-like behaviors and reduces the activation of pro-inflammatory cytokines and the phosphorylation of glucocorticoid receptors at serine 246 induced by neuroinflammation. ( Li, Y; Lin, W; Tang, M; Wang, X; Zhang, J; Zhang, K; Zhao, Y, 2020) |
| "These effects were mediated by the breast cancer oncogene IKKε and its downstream target-the serine biosynthesis pathway as demonstrated by genetic or pharmacological tools." | 1.56 | Macrophages induce malignant traits in mammary epithelium via IKKε/TBK1 kinases and the serine biosynthesis pathway. ( Bentham, RB; Bianchi, K; Carter, E; Dalli, J; Godinho, SA; Grose, R; Hodivala-Dilke, K; Holdsworth, J; Ironside, A; Jones, L; Jones, W; Mataloni, I; Moreno Béjar, R; Szabadkai, G; Uhlik, L; Wilcz-Villega, E; Xu, R, 2020) |
| " Impaired bioavailability of endothelial nitric oxide synthase (eNOS) is one of the main reasons of endothelial dysfunction." | 1.46 | mZD7349 peptide-conjugated PLGA nanoparticles directed against VCAM-1 for targeted delivery of simvastatin to restore dysfunctional HUVECs. ( Amani, A; Deiham, B; Doosti, M; Faramarzi, MA; Imanparast, F; Kobarfard, F; Paknejad, M; Vatannejad, A, 2017) |
| "Mefenamic acid treatment provided significant protection against the elevation of lipid peroxidation, protein oxidation, levels of TNF-α, IL-1β and Bax." | 1.38 | Neuroprotection by mefenamic acid against D-serine: involvement of oxidative stress, inflammation and apoptosis. ( Armagan, G; Kanit, L; Turunc, E; Yalcin, A, 2012) |
| "Inflammation is deleterious for organs with reduced capacity of regeneration, such as the brain." | 1.38 | Effects of non-steroidal antiinflammatory drugs on D-serine-induced oxidative stress in vitro. ( Armagan, G; Kanit, L; Yalcin, A, 2012) |
| "Ethacrynic acid has been used as a safe and effective diuretic for more than 30 years." | 1.33 | Ethacrynic acid inhibits multiple steps in the NF-kappaB signaling pathway. ( Delude, RL; Englert, JA; Fink, MP; Han, Y, 2005) |
| "Streptococcus pneumoniae is the major cause of community-acquired pneumonia and one of the most common causes of death by infectious disease in industrialized countries." | 1.32 | Streptococcus pneumoniae-induced p38 MAPK-dependent phosphorylation of RelA at the interleukin-8 promotor. ( Hammerschmidt, S; Hippenstiel, S; Hocke, AC; Hoffmann, E; Huber, S; Kracht, M; Moog, K; Opitz, B; Rosseau, S; Schmeck, B; Suttorp, N; van Laak, V; Zahlten, J; Zerrahn, J, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (1.92) | 18.7374 |
| 1990's | 4 (3.85) | 18.2507 |
| 2000's | 35 (33.65) | 29.6817 |
| 2010's | 46 (44.23) | 24.3611 |
| 2020's | 17 (16.35) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, D | 1 |
| Xu, S | 1 |
| Wang, Y | 3 |
| Bin, P | 1 |
| Zhu, G | 2 |
| Soman, A | 1 |
| Asha Nair, S | 1 |
| Tu, H | 1 |
| Xiong, W | 1 |
| Zhang, J | 5 |
| Zhao, X | 2 |
| Lin, X | 1 |
| Cappello, A | 2 |
| Mancini, M | 2 |
| Madonna, S | 2 |
| Rinaldo, S | 2 |
| Paone, A | 2 |
| Scarponi, C | 2 |
| Belardo, A | 2 |
| Zolla, L | 2 |
| Zuccotti, A | 2 |
| Panatta, E | 2 |
| Pallotta, S | 2 |
| Annicchiarico-Petruzzelli, M | 2 |
| Albanesi, C | 2 |
| Cutruzzolà, F | 2 |
| Wang, L | 3 |
| Jia, W | 2 |
| Melino, G | 2 |
| Candi, E | 2 |
| Takiishi, T | 1 |
| Xiao, P | 1 |
| Franchimont, M | 1 |
| Gilglioni, EH | 1 |
| Arroba, EN | 1 |
| Gurzov, EN | 1 |
| Bertrand, MJ | 1 |
| Cardozo, AK | 1 |
| Pan, H | 1 |
| Guo, Z | 2 |
| Lv, P | 1 |
| Hu, K | 1 |
| Wu, T | 1 |
| Lin, Z | 1 |
| Xue, Y | 1 |
| Zhang, Y | 3 |
| Rawat, P | 1 |
| Thakur, S | 1 |
| Dogra, S | 1 |
| Jaswal, K | 1 |
| Dehury, B | 1 |
| Mondal, P | 1 |
| Ke, D | 1 |
| Zhang, Z | 1 |
| Liu, J | 1 |
| Chen, P | 1 |
| Dai, Y | 1 |
| Sun, X | 1 |
| Chu, Y | 1 |
| Li, L | 1 |
| He, F | 1 |
| Yin, Z | 1 |
| Wu, C | 1 |
| Xia, Y | 1 |
| Wu, M | 1 |
| Li, P | 1 |
| Zhang, H | 1 |
| Yin, Y | 2 |
| Li, N | 1 |
| Ren, W | 1 |
| Peng, Y | 1 |
| Nakanishi, J | 1 |
| Suzuki, S | 1 |
| Yoshida, K | 1 |
| Hirata-Tsuchiya, S | 1 |
| Haruyama, N | 1 |
| Yamada, S | 1 |
| Shiba, H | 1 |
| Lin, W | 1 |
| Tang, M | 1 |
| Zhao, Y | 1 |
| Zhang, K | 1 |
| Wang, X | 4 |
| Li, Y | 2 |
| Wilcz-Villega, E | 1 |
| Carter, E | 1 |
| Ironside, A | 1 |
| Xu, R | 1 |
| Mataloni, I | 1 |
| Holdsworth, J | 1 |
| Jones, W | 1 |
| Moreno Béjar, R | 1 |
| Uhlik, L | 1 |
| Bentham, RB | 1 |
| Godinho, SA | 1 |
| Dalli, J | 1 |
| Grose, R | 1 |
| Szabadkai, G | 1 |
| Jones, L | 1 |
| Hodivala-Dilke, K | 1 |
| Bianchi, K | 1 |
| Álvarez-Salamero, C | 1 |
| Castillo-González, R | 1 |
| Pastor-Fernández, G | 1 |
| Mariblanca, IR | 1 |
| Pino, J | 1 |
| Cibrian, D | 1 |
| Navarro, MN | 1 |
| He, Z | 1 |
| Tao, D | 1 |
| Xiong, J | 1 |
| Lou, F | 1 |
| Chen, J | 1 |
| Dai, W | 1 |
| Sun, J | 1 |
| Ni, M | 1 |
| Zhou, H | 1 |
| Jin, D | 1 |
| Lu, T | 1 |
| Busuttil, RW | 1 |
| Kupiec-Weglinski, JW | 1 |
| Zhai, Y | 1 |
| Balic, JJ | 1 |
| Albargy, H | 1 |
| Luu, K | 1 |
| Kirby, FJ | 1 |
| Jayasekara, WSN | 1 |
| Mansell, F | 1 |
| Garama, DJ | 1 |
| De Nardo, D | 1 |
| Baschuk, N | 1 |
| Louis, C | 1 |
| Humphries, F | 1 |
| Fitzgerald, K | 1 |
| Latz, E | 1 |
| Gough, DJ | 1 |
| Mansell, A | 1 |
| Beesley, S | 1 |
| Sullenberger, T | 1 |
| Crotty, K | 1 |
| Ailani, R | 1 |
| D'Orio, C | 1 |
| Evans, K | 1 |
| Ogunkunle, EO | 1 |
| Roper, MG | 1 |
| Kumar, SS | 1 |
| Qualmann, B | 1 |
| Kessels, MM | 1 |
| Stokes, CA | 1 |
| Kaur, R | 1 |
| Edwards, MR | 1 |
| Mondhe, M | 1 |
| Robinson, D | 1 |
| Prestwich, EC | 1 |
| Hume, RD | 1 |
| Marshall, CA | 1 |
| Perrie, Y | 1 |
| O'Donnell, VB | 1 |
| Harwood, JL | 1 |
| Sabroe, I | 1 |
| Parker, LC | 1 |
| Riedlinger, T | 1 |
| Dommerholt, MB | 1 |
| Wijshake, T | 1 |
| Kruit, JK | 1 |
| Huijkman, N | 1 |
| Dekker, D | 1 |
| Koster, M | 1 |
| Kloosterhuis, N | 1 |
| Koonen, DPY | 1 |
| de Bruin, A | 1 |
| Baker, D | 1 |
| Hofker, MH | 1 |
| van Deursen, J | 1 |
| Jonker, JW | 1 |
| Schmitz, ML | 2 |
| van de Sluis, B | 1 |
| Zhang, S | 1 |
| Ai, S | 1 |
| Ouyang, W | 1 |
| Le, Y | 1 |
| Tong, J | 1 |
| Yoshihisa, Y | 1 |
| Rehman, MU | 1 |
| Nakagawa, M | 1 |
| Matsukuma, S | 1 |
| Makino, T | 1 |
| Mori, H | 1 |
| Shimizu, T | 2 |
| Zhou, X | 1 |
| Wu, X | 2 |
| Wan, D | 1 |
| Wang, G | 2 |
| Ding, L | 1 |
| Gao, C | 2 |
| Zhang, N | 1 |
| Gan, D | 1 |
| Sun, Y | 1 |
| Xu, L | 1 |
| Luo, Q | 1 |
| Jiang, Z | 1 |
| Li, X | 1 |
| Gong, W | 1 |
| Wang, H | 1 |
| Li, T | 1 |
| Attri, KS | 1 |
| Lewis, RE | 1 |
| Kalil, AC | 1 |
| Bhinderwala, F | 1 |
| Powers, R | 1 |
| Yin, G | 1 |
| Herring, LE | 1 |
| Asara, JM | 1 |
| Lei, YL | 1 |
| Yang, X | 2 |
| Rodriguez, DA | 1 |
| Yang, M | 1 |
| Green, DR | 1 |
| Singh, PK | 1 |
| Wen, H | 1 |
| Giogha, C | 1 |
| Lawlor, KE | 1 |
| Choi, HK | 1 |
| Park, SY | 1 |
| Oh, HJ | 1 |
| Han, EJ | 1 |
| Lee, YH | 1 |
| Lee, J | 2 |
| Jun, WJ | 1 |
| Choi, KC | 1 |
| Yoon, HG | 1 |
| Ramirez-Ortiz, ZG | 1 |
| Pendergraft, WF | 1 |
| Prasad, A | 1 |
| Byrne, MH | 1 |
| Iram, T | 1 |
| Blanchette, CJ | 1 |
| Luster, AD | 1 |
| Hacohen, N | 1 |
| El Khoury, J | 1 |
| Means, TK | 1 |
| da Silva, VR | 1 |
| Rios-Avila, L | 1 |
| Lamers, Y | 1 |
| Ralat, MA | 1 |
| Midttun, Ø | 1 |
| Quinlivan, EP | 1 |
| Garrett, TJ | 1 |
| Coats, B | 1 |
| Shankar, MN | 1 |
| Percival, SS | 1 |
| Chi, YY | 1 |
| Muller, KE | 1 |
| Ueland, PM | 1 |
| Stacpoole, PW | 1 |
| Gregory, JF | 1 |
| Storci, G | 1 |
| Bertoni, S | 1 |
| De Carolis, S | 1 |
| Papi, A | 1 |
| Nati, M | 1 |
| Ceccarelli, C | 1 |
| Pirazzini, C | 1 |
| Garagnani, P | 1 |
| Ferrarini, A | 1 |
| Buson, G | 1 |
| Delledonne, M | 1 |
| Fiorentino, M | 1 |
| Capizzi, E | 1 |
| Gruppioni, E | 1 |
| Taffurelli, M | 1 |
| Santini, D | 1 |
| Franceschi, C | 1 |
| Bandini, G | 1 |
| Bonifazi, F | 1 |
| Bonafé, M | 1 |
| Borsting, E | 1 |
| Patel, SV | 1 |
| Declèves, AE | 1 |
| Lee, SJ | 1 |
| Rahman, QM | 1 |
| Akira, S | 1 |
| Satriano, J | 1 |
| Sharma, K | 1 |
| Vallon, V | 1 |
| Cunard, R | 1 |
| Morimoto, R | 1 |
| Shindou, H | 1 |
| Tarui, M | 1 |
| Li, Z | 1 |
| Lin, F | 1 |
| Zhuo, C | 1 |
| Deng, G | 1 |
| Chen, Z | 1 |
| Yin, S | 1 |
| Gao, Z | 1 |
| Piccioni, M | 1 |
| Tsun, A | 1 |
| Cai, S | 1 |
| Zheng, SG | 1 |
| Li, B | 1 |
| Kwok, W | 1 |
| Clemens, MG | 1 |
| Lopez-Pelaez, M | 1 |
| Lamont, DJ | 1 |
| Peggie, M | 1 |
| Shpiro, N | 1 |
| Gray, NS | 1 |
| Cohen, P | 1 |
| Ren, J | 1 |
| Chen, X | 1 |
| Chen, ZJ | 1 |
| Liu, Z | 1 |
| Zhang, W | 1 |
| Zhang, M | 1 |
| Zhu, H | 1 |
| Moriasi, C | 1 |
| Zou, MH | 1 |
| Takahashi, Y | 1 |
| Hara, K | 1 |
| Haranishi, Y | 1 |
| Terada, T | 1 |
| Obara, G | 1 |
| Sata, T | 1 |
| Kim, MJ | 1 |
| Rangasamy, S | 1 |
| Shim, Y | 1 |
| Song, JM | 1 |
| Rzeniewicz, K | 1 |
| Newe, A | 1 |
| Rey Gallardo, A | 1 |
| Davies, J | 1 |
| Holt, MR | 1 |
| Patel, A | 1 |
| Charras, GT | 1 |
| Stramer, B | 2 |
| Molenaar, C | 1 |
| Tedder, TF | 1 |
| Parsons, M | 1 |
| Ivetic, A | 1 |
| Bhattacharyya, S | 1 |
| Feferman, L | 1 |
| Tobacman, JK | 1 |
| Jokela, T | 1 |
| Oikari, S | 1 |
| Takabe, P | 1 |
| Rilla, K | 1 |
| Kärnä, R | 1 |
| Tammi, M | 1 |
| Tammi, R | 1 |
| Slomiany, BL | 1 |
| Slomiany, A | 1 |
| Ross, EA | 1 |
| Smallie, T | 1 |
| Ding, Q | 1 |
| O'Neil, JD | 1 |
| Cunliffe, HE | 1 |
| Tang, T | 1 |
| Rosner, DR | 1 |
| Klevernic, I | 1 |
| Morrice, NA | 1 |
| Monaco, C | 1 |
| Cunningham, AF | 1 |
| Buckley, CD | 1 |
| Saklatvala, J | 2 |
| Dean, JL | 2 |
| Clark, AR | 2 |
| Tourville, TW | 1 |
| Poynter, ME | 1 |
| DeSarno, MJ | 1 |
| Struglics, A | 1 |
| Beynnon, BD | 1 |
| Kim, OK | 1 |
| Jun, W | 1 |
| Pradère, JP | 1 |
| Hernandez, C | 1 |
| Koppe, C | 1 |
| Friedman, RA | 1 |
| Luedde, T | 1 |
| Schwabe, RF | 1 |
| Imanparast, F | 1 |
| Faramarzi, MA | 1 |
| Vatannejad, A | 1 |
| Paknejad, M | 1 |
| Deiham, B | 1 |
| Kobarfard, F | 1 |
| Amani, A | 1 |
| Doosti, M | 1 |
| Beck, IM | 1 |
| Vanden Berghe, W | 1 |
| Vermeulen, L | 1 |
| Bougarne, N | 1 |
| Vander Cruyssen, B | 1 |
| Haegeman, G | 1 |
| De Bosscher, K | 1 |
| Raivich, G | 1 |
| Kwong, J | 1 |
| Hong, L | 1 |
| Liao, R | 1 |
| Deng, Q | 1 |
| Han, J | 1 |
| Sun, P | 1 |
| Muñoz, MC | 1 |
| Giani, JF | 1 |
| Mayer, MA | 1 |
| Toblli, JE | 1 |
| Turyn, D | 1 |
| Dominici, FP | 1 |
| Yang, HB | 1 |
| Xie, QJ | 1 |
| Liu, XH | 1 |
| Hu, XD | 1 |
| Zanet, J | 1 |
| Millard, T | 1 |
| Martin, P | 1 |
| Payre, F | 1 |
| Plaza, S | 1 |
| Gomaraschi, M | 1 |
| Putt, WE | 1 |
| Pozzi, S | 1 |
| Iametti, S | 1 |
| Barbiroli, A | 1 |
| Bonomi, F | 1 |
| Favari, E | 1 |
| Bernini, F | 1 |
| Franceschini, G | 1 |
| Talmud, PJ | 1 |
| Calabresi, L | 1 |
| Elks, CM | 1 |
| Francis, J | 1 |
| Yang, L | 1 |
| Qian, Z | 1 |
| Ji, H | 1 |
| Yang, R | 1 |
| Xi, L | 1 |
| Sheng, L | 1 |
| Zhao, B | 1 |
| Zhang, X | 1 |
| Atianjoh, FE | 1 |
| Yaster, M | 1 |
| Takamiya, K | 1 |
| Xia, J | 1 |
| Gauda, EB | 1 |
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8 reviews available for serine and Innate Inflammatory Response
| Article | Year |
|---|---|
Unfolding the cascade of SERPINA3: Inflammation to cancer.
Topics: Acute-Phase Proteins; Biomarkers, Tumor; Carcinogens; Humans; Inflammation; Neoplasms; Serine; Serin | 2022 |
RIPK1 and RIPK3 inhibitors: potential weapons against inflammation to treat diabetic complications.
Topics: Diabetes Complications; Diabetes Mellitus; Diabetic Nephropathies; Humans; Inflammation; Receptor-In | 2023 |
Phosphorylation of 5-LOX: The Potential Set-point of Inflammation.
Topics: Animals; Arachidonate 5-Lipoxygenase; Brain; Brain Injuries; Humans; Inflammation; Lipoxygenase Inhi | 2020 |
The Role of Protein Arginine Methylation as Post-Translational Modification on Actin Cytoskeletal Components in Neuronal Structure and Function.
Topics: Actin Cytoskeleton; Actins; Animals; Arginine; Axons; Cells, Cultured; Cytoskeleton; Cytosol; Dendri | 2021 |
The control of inflammation via the phosphorylation and dephosphorylation of tristetraprolin: a tale of two phosphatases.
Topics: Amino Acid Sequence; Animals; Humans; Inflammation; Mice, Knockout; Phosphoric Monoester Hydrolases; | 2016 |
c-Jun expression, activation and function in neural cell death, inflammation and repair.
Topics: Animals; Cell Death; Gene Expression; Humans; Inflammation; Models, Biological; Neurons; Proto-Oncog | 2008 |
Central adiposity, systemic inflammation, and the metabolic syndrome.
Topics: Abdominal Fat; Adipokines; Adiponectin; Adiposity; C-Reactive Protein; Cytokines; Diet; Humans; Infl | 2010 |
An unconventional hypothesis of oxidation in Alzheimer's disease: intersections with excitotoxicity.
Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Cystine; Glutamates; Humans; Inflam | 2004 |
96 other studies available for serine and Innate Inflammatory Response
| Article | Year |
|---|---|
The Amino Acid-mTORC1 Pathway Mediates APEC TW-XM-Induced Inflammation in bEnd.3 Cells.
Topics: Amino Acid Transport Systems; Amino Acids; Animals; Bird Diseases; Blood-Brain Barrier; Cell Line; D | 2021 |
Tyrosine phosphorylation regulates RIPK1 activity to limit cell death and inflammation.
Topics: Animals; Apoptosis; Inflammation; Mice; Phosphorylation; Protein Kinases; Receptor-Interacting Prote | 2022 |
Extracellular serine empowers epidermal proliferation and psoriasis-like symptoms.
Topics: Animals; Cell Proliferation; Glycine; Glycine Hydroxymethyltransferase; Humans; Inflammation; Mice; | 2022 |
Extracellular serine empowers epidermal proliferation and psoriasis-like symptoms.
Topics: Animals; Cell Proliferation; Glycine; Glycine Hydroxymethyltransferase; Humans; Inflammation; Mice; | 2022 |
Extracellular serine empowers epidermal proliferation and psoriasis-like symptoms.
Topics: Animals; Cell Proliferation; Glycine; Glycine Hydroxymethyltransferase; Humans; Inflammation; Mice; | 2022 |
Extracellular serine empowers epidermal proliferation and psoriasis-like symptoms.
Topics: Animals; Cell Proliferation; Glycine; Glycine Hydroxymethyltransferase; Humans; Inflammation; Mice; | 2022 |
Inhibition of RIPK1 kinase does not affect diabetes development: β-Cells survive RIPK1 activation.
Topics: Animals; Diabetes Mellitus, Type 1; Humans; Inflammation; Mice; Obesity; Protein Kinases; Receptor-I | 2023 |
Proline/serine-rich coiled-coil protein 1 inhibits macrophage inflammation and delays atherosclerotic progression by binding to Annexin A2.
Topics: Animals; Annexin A2; Atherosclerosis; Coronary Artery Disease; Inflammation; Macrophages; Mice; Mice | 2023 |
Diet-induced induction of hepatic serine/threonine kinase STK38 triggers proinflammation and hepatic lipid accumulation.
Topics: Animals; Diet, High-Fat; Inflammation; Insulin Resistance; Lipids; Lipogenesis; Liver; Mice; Mice, I | 2023 |
l-Serine Lowers the Inflammatory Responses during Pasteurella multocida Infection.
Topics: Animals; Cells, Cultured; Disease Models, Animal; Female; Host-Pathogen Interactions; Inflammation; | 2019 |
Dentin phosphoprotein inhibits lipopolysaccharide-induced macrophage activation independent of its serine/aspartic acid-rich repeats.
Topics: Animals; Aspartic Acid; Dentin; Extracellular Matrix Proteins; Inflammation; Lipopolysaccharides; Ma | 2020 |
Inhibition of JNK ameliorates depressive-like behaviors and reduces the activation of pro-inflammatory cytokines and the phosphorylation of glucocorticoid receptors at serine 246 induced by neuroinflammation.
Topics: Amygdala; Animals; Anthracenes; Brain; Cytokines; Depression; Hippocampus; Hypothalamo-Hypophyseal S | 2020 |
Macrophages induce malignant traits in mammary epithelium via IKKε/TBK1 kinases and the serine biosynthesis pathway.
Topics: Aminopyridines; Animals; Breast Neoplasms; Culture Media, Conditioned; Epithelial Cells; Female; Hum | 2020 |
IL-23 signaling regulation of pro-inflammatory T-cell migration uncovered by phosphoproteomics.
Topics: Animals; Cell Movement; Imiquimod; Inflammation; Interleukin-23 Subunit p19; Janus Kinase 2; Mice, I | 2020 |
Isoform- and Cell Type-Specific Roles of Glycogen Synthase Kinase 3 N-Terminal Serine Phosphorylation in Liver Ischemia Reperfusion Injury.
Topics: Animals; Autophagy; Cell Death; Glycogen Synthase Kinase 3; Hepatocytes; Immunity, Innate; Inflammat | 2020 |
STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1β expression.
Topics: Animals; Cell Line; Cells, Cultured; Gene Expression; Glycolysis; Inflammation; Interleukin-1beta; L | 2020 |
D-serine mitigates cell loss associated with temporal lobe epilepsy.
Topics: Animals; Astrocytes; Behavior, Animal; Brain; Entorhinal Cortex; Epilepsy, Temporal Lobe; Gliosis; I | 2020 |
Human rhinovirus-induced inflammatory responses are inhibited by phosphatidylserine containing liposomes.
Topics: Anti-Inflammatory Agents; Cell Line, Transformed; Cytokines; Humans; Inflammation; Liposomes; Membra | 2017 |
NF-κB p65 serine 467 phosphorylation sensitizes mice to weight gain and TNFα-or diet-induced inflammation.
Topics: Aging; Amino Acid Substitution; Animals; Gene Expression Regulation; Gene Knock-In Techniques; Human | 2017 |
Sepsis-induced selective loss of NMDA receptors modulates hippocampal neuropathology in surviving septic mice.
Topics: Animals; Cyclic AMP Response Element-Binding Protein; Hippocampus; Inflammation; Lipopolysaccharides | 2017 |
Inflammatory cytokine-mediated induction of serine racemase in atopic dermatitis.
Topics: Adult; Animals; Cell Differentiation; Cytokines; Dermatitis, Atopic; Epidermis; Female; Gene Express | 2018 |
Effects of Dietary Serine Supplementation on Intestinal Integrity, Inflammation and Oxidative Status in Early-Weaned Piglets.
Topics: Animals; Apoptosis; Catalase; Cytokines; Dietary Supplements; Glutathione Peroxidase; Ileum; Inflamm | 2018 |
Neuroprotective effect of l-serine against white matter demyelination by harnessing and modulating inflammation in mice.
Topics: Animals; Anxiety; Axons; Calcium-Binding Proteins; Corpus Callosum; Demyelinating Diseases; Explorat | 2019 |
O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3.
Topics: Animals; Apoptosis; Cell Line; Glucose; Humans; Immunity, Innate; Inflammation; Mice; Mice, Inbred C | 2019 |
Sugar Fix Keeps RIPK3 at Bay.
Topics: Humans; Inflammation; N-Acetylglucosaminyltransferases; Receptor-Interacting Protein Serine-Threonin | 2019 |
PKA negatively regulates PP2Cβ to activate NF-κB-mediated inflammatory signaling.
Topics: Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Stability; Gene Expression Regulation, Enzym | 2013 |
The scavenger receptor SCARF1 mediates the clearance of apoptotic cells and prevents autoimmunity.
Topics: Animals; Apoptosis; Autoimmune Diseases; Autoimmunity; Complement C1q; Female; Inflammation; Male; M | 2013 |
Metabolite profile analysis reveals functional effects of 28-day vitamin B-6 restriction on one-carbon metabolism and tryptophan catabolic pathways in healthy men and women.
Topics: Adult; Biomarkers; Creatine; Cystathionine; Female; Humans; Inflammation; Kynurenic Acid; Kynurenine | 2013 |
Slug/β-catenin-dependent proinflammatory phenotype in hypoxic breast cancer stem cells.
Topics: Autocrine Communication; beta Catenin; Breast Neoplasms; Cell Hypoxia; Cytokines; DNA Damage; Female | 2013 |
Tribbles homolog 3 attenuates mammalian target of rapamycin complex-2 signaling and inflammation in the diabetic kidney.
Topics: Albuminuria; Animals; Carrier Proteins; Cell Cycle Proteins; Diabetic Nephropathies; Endoplasmic Ret | 2014 |
Rapid production of platelet-activating factor is induced by protein kinase Cα-mediated phosphorylation of lysophosphatidylcholine acyltransferase 2 protein.
Topics: 1-Acylglycerophosphocholine O-Acyltransferase; Animals; CHO Cells; Cricetulus; Gene Knockdown Techni | 2014 |
PIM1 kinase phosphorylates the human transcription factor FOXP3 at serine 422 to negatively regulate its activity under inflammation.
Topics: Cell Proliferation; CTLA-4 Antigen; Forkhead Transcription Factors; Gene Expression Regulation; Gene | 2014 |
Rho-kinase activation contributes to Lps-induced impairment of endothelial nitric oxide synthase activation by endothelin-1 in cultured hepatic sinusoidal endothelial cells.
Topics: Actins; Amides; Animals; Caveolin 1; Cells, Cultured; Cofilin 1; Endothelial Cells; Endothelin-1; En | 2014 |
Protein kinase IKKβ-catalyzed phosphorylation of IRF5 at Ser462 induces its dimerization and nuclear translocation in myeloid cells.
Topics: Active Transport, Cell Nucleus; Animals; Cell Line; Gene Expression Regulation, Enzymologic; Humans; | 2014 |
IKKβ is an IRF5 kinase that instigates inflammation.
Topics: Alanine; Animals; Cytokines; HEK293 Cells; Humans; I-kappa B Kinase; Inflammation; Interferon Regula | 2014 |
Liver kinase B1 suppresses lipopolysaccharide-induced nuclear factor κB (NF-κB) activation in macrophages.
Topics: AMP-Activated Protein Kinases; Animals; Endotoxins; Gene Expression Regulation, Enzymologic; I-kappa | 2015 |
Antinociceptive effect of intracerebroventricular administration of glycine transporter-2 inhibitor ALX1393 in rat models of inflammatory and neuropathic pain.
Topics: Analgesics; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Glycine Plasma Membra | 2015 |
Cell lysis-free quantum dot multicolor cellular imaging-based mechanism study for TNF-α-induced insulin resistance.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibodies; Aspirin; Cinnamates; Forkhead Box Protein O1; F | 2015 |
L-selectin shedding is activated specifically within transmigrating pseudopods of monocytes to regulate cell polarity in vitro.
Topics: Amino Acid Sequence; Cell Adhesion; Cell Movement; Cell Polarity; Cytoplasm; Fluorescence Resonance | 2015 |
Carrageenan Inhibits Insulin Signaling through GRB10-mediated Decrease in Tyr(P)-IRS1 and through Inflammation-induced Increase in Ser(P)307-IRS1.
Topics: Animals; Carrageenan; GATA2 Transcription Factor; Gene Expression; GRB10 Adaptor Protein; Hep G2 Cel | 2015 |
Interleukin-1β-induced Reduction of CD44 Ser-325 Phosphorylation in Human Epidermal Keratinocytes Promotes CD44 Homomeric Complexes, Binding to Ezrin, and Extended, Monocyte-adhesive Hyaluronan Coats.
Topics: Cell Line, Tumor; Cell Membrane; Cell Movement; Cytoskeletal Proteins; Cytoskeleton; Epidermis; Exon | 2015 |
Regulatory role of guanine nucleotide exchange factor (GEF) Dock180 phosphorylation on Tyr/Ser in mediation of gastric mucosal Rac1 activation in response to Helicobacter pylori and ghrelin.
Topics: Animals; Gastric Mucosa; Ghrelin; Guanine Nucleotide Exchange Factors; Helicobacter Infections; Heli | 2015 |
Dominant Suppression of Inflammation via Targeted Mutation of the mRNA Destabilizing Protein Tristetraprolin.
Topics: Alanine; Amino Acid Substitution; Animals; Cell Line; Cytokines; Female; Gene Expression; Inflammati | 2015 |
Relationship between synovial fluid ARGS-aggrecan fragments, cytokines, MMPs, and TIMPs following acute ACL injury: A cross-sectional study.
Topics: Adolescent; Adult; Aggrecans; Alanine; Anterior Cruciate Ligament Injuries; Arginine; Body Mass Inde | 2015 |
Effect of Cudrania tricuspidata and Kaempferol in Endoplasmic Reticulum Stress-Induced Inflammation and Hepatic Insulin Resistance in HepG2 Cells.
Topics: CCAAT-Enhancer-Binding Protein-alpha; Endoplasmic Reticulum Stress; Hep G2 Cells; Humans; Inflammati | 2016 |
Negative regulation of NF-κB p65 activity by serine 536 phosphorylation.
Topics: Amino Acid Substitution; Animals; Inflammation; Lipopolysaccharides; Mice, Transgenic; Mutation, Mis | 2016 |
mZD7349 peptide-conjugated PLGA nanoparticles directed against VCAM-1 for targeted delivery of simvastatin to restore dysfunctional HUVECs.
Topics: Anti-Inflammatory Agents; Cells, Cultured; Drug Carriers; Drug Compounding; Drug Liberation; Human U | 2017 |
Altered subcellular distribution of MSK1 induced by glucocorticoids contributes to NF-kappaB inhibition.
Topics: Cell Line; Cytokines; Cytoplasm; Enzyme Induction; Exportin 1 Protein; Gene Expression Regulation; G | 2008 |
p38alpha and p38gamma mediate oncogenic ras-induced senescence through differential mechanisms.
Topics: Cellular Senescence; Fibroblasts; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Mito | 2009 |
TANK-binding kinase 1 mediates phosphorylation of insulin receptor at serine residue 994: a potential link between inflammation and insulin resistance.
Topics: Animals; Diabetes Mellitus, Experimental; Inflammation; Insulin Resistance; Liver; Male; Mice; Mice, | 2009 |
Peripheral inflammation increased the synaptic expression of NMDA receptors in spinal dorsal horn.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Excitatory Amino Acid Agonists; Excitatory A | 2009 |
Fascin is required for blood cell migration during Drosophila embryogenesis.
Topics: Amino Acid Sequence; Animal Structures; Animals; Blood Cells; Carrier Proteins; Cell Movement; Cell | 2009 |
Structure and function of the apoA-IV T347S and Q360H common variants.
Topics: Amino Acid Substitution; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apolipoproteins A; Cell L | 2010 |
Inhibitory effect on protein kinase Ctheta by Crocetin attenuates palmitate-induced insulin insensitivity in 3T3-L1 adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Biological Transport; Carotenoids; Deoxyglucose; Enzyme Activatio | 2010 |
Spinal cord protein interacting with C kinase 1 is required for the maintenance of complete Freund's adjuvant-induced inflammatory pain but not for incision-induced post-operative pain.
Topics: Animals; Carrier Proteins; Cell Cycle Proteins; Disease Models, Animal; Freund's Adjuvant; Gene Expr | 2010 |
Extracellular high dosages of adenosine triphosphate induce inflammatory response and insulin resistance in rat adipocytes.
Topics: Adenosine Triphosphate; Adipocytes; Animals; Cells, Cultured; Glucose; Inflammation; Insulin; Insuli | 2010 |
Luteolin inhibits inflammatory response and improves insulin sensitivity in the endothelium.
Topics: Animals; Aorta; Cytokines; Endothelium, Vascular; Gene Expression Regulation; I-kappa B Kinase; In V | 2011 |
Metformin counters both lipolytic/inflammatory agents-decreased hormone sensitive lipase phosphorylation at Ser-554 and -induced lipolysis in human adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adipocytes; Adult; Aged; Colforsin; Female; Humans; Hypoglycemic Agents | 2011 |
The G82S polymorphism promotes glycosylation of the receptor for advanced glycation end products (RAGE) at asparagine 81: comparison of wild-type rage with the G82S polymorphic variant.
Topics: Asparagine; Cell Line; Cell Membrane; Gene Expression Regulation; Glycine; Glycosylation; Humans; In | 2011 |
Neuroprotection by mefenamic acid against D-serine: involvement of oxidative stress, inflammation and apoptosis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Brain; Inflammation; Mefenamic Acid; Ne | 2012 |
Combined chromatin and expression analysis reveals specific regulatory mechanisms within cytokine genes in the macrophage early immune response.
Topics: Cell Differentiation; Chromatin; Chromatin Immunoprecipitation; CpG Islands; Cytokines; Gene Express | 2012 |
Effects of non-steroidal antiinflammatory drugs on D-serine-induced oxidative stress in vitro.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Inflammation; Lipid Peroxida | 2012 |
IL-1β-mediated up-regulation of DEC1 in human gingiva cells via the Akt pathway.
Topics: Animals; Bacteroidaceae Infections; Blotting, Western; Cells, Cultured; Chromones; Epithelial Cells; | 2012 |
Differential chemoattractant response in adipocytes and macrophages to the action of acylation stimulating protein.
Topics: 3T3-L1 Cells; Acylation; Adipocytes; Adiponectin; Animals; Chemokine CCL2; Chemokines; Coculture Tec | 2013 |
Cyclin-dependent kinase 6 phosphorylates NF-κB P65 at serine 536 and contributes to the regulation of inflammatory gene expression.
Topics: Animals; Apoptosis; Cell Nucleus; Cell Proliferation; Cyclin-Dependent Kinase 6; Gene Expression Reg | 2012 |
A 16-residue peptide fragment of macrophage migration inhibitory factor, MIF-(50-65), exhibits redox activity and has MIF-like biological functions.
Topics: 3T3 Cells; Amino Acid Motifs; Amino Acid Sequence; Animals; Biotinylation; Catalysis; Cell Cycle Pro | 2003 |
Stimulation of signal transducer and activator of transcription-1 (STAT1)-dependent gene transcription by lipopolysaccharide and interferon-gamma is regulated by mammalian target of rapamycin.
Topics: Androstadienes; Apoptosis; Blotting, Northern; Cell Division; Chromones; Cytokines; DNA-Binding Prot | 2003 |
Efficiency of a cysteine-taurine-threonine-serine supplemented parenteral nutrition in an experimental model of acute inflammation.
Topics: Acute Disease; Animals; Cysteine; Dietary Supplements; Inflammation; Male; Parenteral Nutrition; Pro | 2003 |
Production of N(epsilon)-(carboxymethyl)lysine is impaired in mice deficient in NADPH oxidase: a role for phagocyte-derived oxidants in the formation of advanced glycation end products during inflammation.
Topics: Acetaldehyde; Animals; Glycation End Products, Advanced; Hydrogen Peroxide; Inflammation; Lysine; Me | 2003 |
Protein kinases regulate the phosphorylation of the GluR1 subunit of AMPA receptors of spinal cord in rats following noxious stimulation.
Topics: Amino Acid Sequence; Animals; Capsaicin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; In | 2003 |
E-Selectin and restenosis after femoropopliteal angioplasty: prognostic impact of the Ser128Arg genotype and plasma levels.
Topics: Aged; Aged, 80 and over; Angioplasty; Angioplasty, Balloon; Arginine; Codon; Coronary Restenosis; E- | 2004 |
Requirement of histone deacetylase activity for signaling by STAT1.
Topics: Active Transport, Cell Nucleus; Apoptosis; bcl-X Protein; Blotting, Western; Butyrates; Cell Line; C | 2004 |
The interaction of protein kinase C isozymes alpha, iota, and theta with the cytoplasmic domain of L-selectin is modulated by phosphorylation of the receptor.
Topics: Amino Acid Sequence; Calcium; CD3 Complex; Cross-Linking Reagents; Cyclic GMP; Cytoplasm; Dose-Respo | 2004 |
Streptococcus pneumoniae-induced p38 MAPK-dependent phosphorylation of RelA at the interleukin-8 promotor.
Topics: Animals; Blotting, Western; Bronchi; Cell Nucleus; Cells, Cultured; Chemokines; Chromatin Immunoprec | 2004 |
Ethacrynic acid inhibits multiple steps in the NF-kappaB signaling pathway.
Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Cell Line; Cell Nucleus; Cell Survival; Cell-F | 2005 |
Regulatory interfaces between the stress protein response and other gene expression programs in the cell.
Topics: 14-3-3 Proteins; Animals; Binding Sites; Cell Line; Cell Nucleus; CHO Cells; Cricetinae; Cytoplasm; | 2005 |
1.70 A X-ray structure of human apo kallikrein 1: structural changes upon peptide inhibitor/substrate binding.
Topics: Animals; Aprotinin; Binding Sites; Biomarkers; Blood Pressure; Cattle; Cloning, Molecular; Crystallo | 2005 |
Induction of serine racemase by inflammatory stimuli is dependent on AP-1.
Topics: Amino Acid Isomerases; Animals; Anthracenes; Anti-Inflammatory Agents; Blotting, Western; Cell Line; | 2004 |
A role of STAT3 in Rho GTPase-regulated cell migration and proliferation.
Topics: Actins; Active Transport, Cell Nucleus; Animals; cdc42 GTP-Binding Protein; Cell Movement; Cell Nucl | 2005 |
Proteolysis of macrophage inflammatory protein-1alpha isoforms LD78beta and LD78alpha by neutrophil-derived serine proteases.
Topics: Amino Acid Sequence; Cathepsin G; Cathepsins; Chemokine CCL3; Chemokine CCL4; Chemokines; Chemotaxis | 2005 |
Phosphorylation of Ser24 in the pleckstrin homology domain of insulin receptor substrate-1 by Mouse Pelle-like kinase/interleukin-1 receptor-associated kinase: cross-talk between inflammatory signaling and insulin signaling that may contribute to insulin
Topics: Adipose Tissue; Animals; Blood Proteins; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; CO | 2005 |
Endothelial thrombomodulin induces Ca2+ signals and nitric oxide synthesis through epidermal growth factor receptor kinase and calmodulin kinase II.
Topics: Atherosclerosis; Blotting, Western; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cal | 2005 |
Positive regulation of IkappaB kinase signaling by protein serine/threonine phosphatase 2A.
Topics: Active Transport, Cell Nucleus; Adenosine Triphosphate; Alkenes; Animals; B-Lymphocytes; Catalysis; | 2005 |
Nitric oxide regulates prolidase activity by serine/threonine phosphorylation.
Topics: Animals; Blotting, Western; Cyclic GMP; Dipeptidases; DNA, Complementary; Dose-Response Relationship | 2005 |
Site-specific monoubiquitination of IkappaB kinase IKKbeta regulates its phosphorylation and persistent activation.
Topics: Active Transport, Cell Nucleus; Arginine; Binding Sites; Cell Line; Cell Proliferation; Cytokines; C | 2005 |
Phosphorylation of HSF1 by MAPK-activated protein kinase 2 on serine 121, inhibits transcriptional activity and promotes HSP90 binding.
Topics: Amino Acid Sequence; Animals; Blotting, Western; Cell Line; Cell Nucleus; Chromatography, Gel; Dimer | 2006 |
A specific p47phox -serine phosphorylated by convergent MAPKs mediates neutrophil NADPH oxidase priming at inflammatory sites.
Topics: Amino Acid Sequence; Arthritis, Rheumatoid; Cell Line; Enzyme Activation; Enzyme Inhibitors; Geniste | 2006 |
IKK-i/IKKepsilon controls constitutive, cancer cell-associated NF-kappaB activity via regulation of Ser-536 p65/RelA phosphorylation.
Topics: Cell Line; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; HeLa Cells; | 2006 |
Characterization of the PC4 binding domain and its interactions with HNF4alpha.
Topics: Amino Acid Sequence; Cell Line, Tumor; DNA-Binding Proteins; Hepatocyte Nuclear Factor 4; Humans; In | 2007 |
The LOC387715 polymorphism, inflammatory markers, smoking, and age-related macular degeneration. A population-based case-control study.
Topics: Aged; Aged, 80 and over; Alanine; Biomarkers; C-Reactive Protein; Case-Control Studies; Genetic Pred | 2008 |
The impact of CREB and its phosphorylation at Ser142 on inflammatory nociception.
Topics: Animals; Cyclic AMP Response Element-Binding Protein; Down-Regulation; Inflammation; Male; Mice; Mut | 2007 |
Heme oxygenase-1 inhibits the expression of adhesion molecules associated with endothelial cell activation via inhibition of NF-kappaB RelA phosphorylation at serine 276.
Topics: Animals; Cell Adhesion Molecules; Cells, Cultured; Down-Regulation; Endothelial Cells; Ferric Compou | 2007 |
Role of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptor subunit GluR1 in spinal dorsal horn in inflammatory nociception and neuropathic nociception in rat.
Topics: Amino Acid Sequence; Animals; Disease Models, Animal; Freund's Adjuvant; Hyperalgesia; Inflammation; | 2008 |
Hepatic expression of mature transforming growth factor beta 1 in transgenic mice results in multiple tissue lesions.
Topics: Animals; Apoptosis; Cell Division; Cells, Cultured; Codon; Crosses, Genetic; Cysteine; DNA, Compleme | 1995 |
Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to convert hydroxy-amino acids into glycolaldehyde, 2-hydroxypropanal, and acrolein. A mechanism for the generation of highly reactive alpha-hydroxy and alpha,beta-unsaturated
Topics: Acetaldehyde; Acrolein; Aldehydes; Amino Acids; Catalase; Chlorides; Chromatography, High Pressure L | 1997 |
Studies on selection blockers. 5. Design, synthesis, and biological profile of sialyl Lewis x mimetics based on modified serine-glutamic acid dipeptides.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dipeptides; Drug Design; Female; Immunoglobulin E; | 1997 |
The myeloperoxidase system of human phagocytes generates Nepsilon-(carboxymethyl)lysine on proteins: a mechanism for producing advanced glycation end products at sites of inflammation.
Topics: Aldehydes; Catalase; Cations; Cells, Cultured; Chelating Agents; Glycosylation; Humans; Hydrogen Per | 1999 |
The erythrocyte plasma distribution of amino acids in health and disease.
Topics: Acute Disease; Adolescent; Adult; Alanine; Amino Acids; Anemia, Hemolytic; Anemia, Pernicious; Bronc | 1968 |
[Separation of low molecular weight ninhydrine positive substances in pleural punctates. Contribution to the problem of inflammation].
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Chromatography; Chromatography, Gel; Electrophoresis; | 1968 |