serine has been researched along with Injury, Myocardial Reperfusion in 13 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In human heart failure, Ser199 (equivalent to Ser200 in mouse) of cTnI (cardiac troponin I) is significantly hyperphosphorylated, and in vitro studies suggest that it enhances myofilament calcium sensitivity and alters calpain-mediated cTnI proteolysis." | 3.85 | Heart Failure-Related Hyperphosphorylation in the Cardiac Troponin I C Terminus Has Divergent Effects on Cardiac Function In Vivo. ( Heravi, A; Kass, DA; Keceli, G; Li, Y; Murphy, AM; Okumus, N; Paolocci, N; Ramirez-Correa, G; Takahashi, C; Zhang, P; Zhu, G, 2017) |
| "Sphingolipids have been implicated in anoxia injury, but the pathomechanism is unknown." | 1.51 | 1-Deoxydihydroceramide causes anoxic death by impairing chaperonin-mediated protein folding. ( Abegg, D; Adibekian, A; Gentina, S; Gomez, L; Guex, N; Hannich, JT; Haribowo, AG; Martinou, JC; Ovize, M; Paillard, M; Pillot, B; Riezman, H; Thibault, H; Zumbuehl, A, 2019) |
| "On leptin treatment, mitochondrial permeability transition pore opening was delayed by 43% (P < 0." | 1.35 | The cardioprotective actions of leptin are lost in the Zucker obese (fa/fa) rat. ( Davidson, SM; Dixon, RA; Smith, CC; Wynne, AM; Yellon, DM, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (38.46) | 29.6817 |
| 2010's | 7 (53.85) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Hannich, JT | 1 |
| Haribowo, AG | 1 |
| Gentina, S | 1 |
| Paillard, M | 1 |
| Gomez, L | 2 |
| Pillot, B | 1 |
| Thibault, H | 1 |
| Abegg, D | 1 |
| Guex, N | 1 |
| Zumbuehl, A | 1 |
| Adibekian, A | 1 |
| Ovize, M | 1 |
| Martinou, JC | 1 |
| Riezman, H | 1 |
| Hurst, S | 1 |
| Gonnot, F | 1 |
| Dia, M | 1 |
| Crola Da Silva, C | 1 |
| Sheu, SS | 1 |
| Li, Y | 1 |
| Zhu, G | 1 |
| Paolocci, N | 1 |
| Zhang, P | 1 |
| Takahashi, C | 1 |
| Okumus, N | 1 |
| Heravi, A | 1 |
| Keceli, G | 1 |
| Ramirez-Correa, G | 1 |
| Kass, DA | 1 |
| Murphy, AM | 1 |
| Luo, T | 1 |
| Liu, H | 1 |
| Kim, JK | 1 |
| Dixon, RA | 1 |
| Davidson, SM | 1 |
| Wynne, AM | 1 |
| Yellon, DM | 1 |
| Smith, CC | 1 |
| Linares-Palomino, J | 1 |
| Husainy, MA | 1 |
| Lai, VK | 1 |
| Dickenson, JM | 1 |
| Galiñanes, M | 1 |
| Lv, L | 1 |
| Jiang, SS | 1 |
| Xu, J | 1 |
| Gong, JB | 1 |
| Cheng, Y | 1 |
| Florea, S | 1 |
| Anjak, A | 1 |
| Cai, WF | 1 |
| Qian, J | 1 |
| Vafiadaki, E | 1 |
| Figueria, S | 1 |
| Haghighi, K | 1 |
| Rubinstein, J | 1 |
| Lorenz, J | 1 |
| Kranias, EG | 1 |
| Yang, C | 1 |
| Talukder, MA | 1 |
| Varadharaj, S | 1 |
| Velayutham, M | 1 |
| Zweier, JL | 1 |
| Stephanou, A | 1 |
| Scarabelli, TM | 1 |
| Townsend, PA | 1 |
| Bell, R | 1 |
| Yellon, D | 1 |
| Knight, RA | 1 |
| Latchman, DS | 1 |
| Mattiazzi, A | 1 |
| Mundiña-Weilenmann, C | 1 |
| Vittone, L | 1 |
| Said, M | 1 |
| Fang, JK | 1 |
| Prabu, SK | 1 |
| Sepuri, NB | 1 |
| Raza, H | 1 |
| Anandatheerthavarada, HK | 1 |
| Galati, D | 1 |
| Spear, J | 1 |
| Avadhani, NG | 1 |
| MacGowan, GA | 1 |
| Du, C | 1 |
| Cowan, DB | 1 |
| Stamm, C | 1 |
| McGowan, FX | 1 |
| Solaro, RJ | 1 |
| Koretsky, AP | 1 |
| Del Nido, PJ | 1 |
13 other studies available for serine and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
1-Deoxydihydroceramide causes anoxic death by impairing chaperonin-mediated protein folding.
Topics: Alanine; Animals; Animals, Genetically Modified; Caenorhabditis elegans; Cell Division; Chaperonins; | 2019 |
Phosphorylation of cyclophilin D at serine 191 regulates mitochondrial permeability transition pore opening and cell death after ischemia-reperfusion.
Topics: Animals; Cell Death; Ischemia; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Mitocho | 2020 |
Heart Failure-Related Hyperphosphorylation in the Cardiac Troponin I C Terminus Has Divergent Effects on Cardiac Function In Vivo.
Topics: Adrenergic beta-Agonists; Animals; Calpain; Disease Models, Animal; Genetic Predisposition to Diseas | 2017 |
Estrogen Protects the Female Heart from Ischemia/Reperfusion Injury through Manganese Superoxide Dismutase Phosphorylation by Mitochondrial p38β at Threonine 79 and Serine 106.
Topics: Animals; Estradiol; Female; Mitochondria, Heart; Myocardial Reperfusion Injury; Ovariectomy; p38 Mit | 2016 |
The cardioprotective actions of leptin are lost in the Zucker obese (fa/fa) rat.
Topics: Animals; Cardiotonic Agents; Heart Ventricles; Leptin; Male; Mitochondrial Membrane Transport Protei | 2009 |
Selective blockade of protein kinase B protects the rat and human myocardium against ischaemic injury.
Topics: Adult; Aged; Aged, 80 and over; Animals; Apoptosis; Creatine Kinase; Dose-Response Relationship, Dru | 2010 |
Protective effect of ligustrazine against myocardial ischaemia reperfusion in rats: the role of endothelial nitric oxide synthase.
Topics: Animals; Apoptosis; Cardiotonic Agents; Caspase 3; Enzyme Inhibitors; Male; Myocardial Infarction; M | 2012 |
Constitutive phosphorylation of inhibitor-1 at Ser67 and Thr75 depresses calcium cycling in cardiomyocytes and leads to remodeling upon aging.
Topics: Aging; Animals; Calcium; Carrier Proteins; Mice; Mice, Transgenic; Myocardial Contraction; Myocardia | 2012 |
Early ischaemic preconditioning requires Akt- and PKA-mediated activation of eNOS via serine1176 phosphorylation.
Topics: Animals; Blotting, Western; Coronary Vessels; Cyclic AMP-Dependent Protein Kinases; Disease Models, | 2013 |
The carboxyl-terminal activation domain of the STAT-1 transcription factor enhances ischemia/reperfusion-induced apoptosis in cardiac myocytes.
Topics: Animals; Animals, Newborn; Apoptosis; Binding Sites; DNA-Binding Proteins; Genotype; In Situ Nick-En | 2002 |
Phosphorylation of phospholamban in ischemia-reperfusion injury: functional role of Thr17 residue.
Topics: Animals; Calcium; Calcium-Binding Proteins; In Vitro Techniques; Male; Myocardial Contraction; Myoca | 2004 |
Site specific phosphorylation of cytochrome c oxidase subunits I, IVi1 and Vb in rabbit hearts subjected to ischemia/reperfusion.
Topics: Amino Acid Sequence; Animals; Chromatography, Liquid; Electron Transport Complex IV; Electrophoresis | 2007 |
Ischemic dysfunction in transgenic mice expressing troponin I lacking protein kinase C phosphorylation sites.
Topics: Alanine; Animals; Binding Sites; Calcium; Feedback; Female; Homeostasis; In Vitro Techniques; Mice; | 2001 |