serine has been researched along with Infarction, Middle Cerebral Artery in 11 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Infarction, Middle Cerebral Artery: NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the neuroprotective effect of L-serine and its underlying mechanisms, focal cerebral ischemia was induced in rats by occlusion of middle cerebral artery (MCAO) with a suture, and reperfusion was given by filament withdrawal 2 hr later." | 7.76 | Neuroprotective effect of L-serine against temporary cerebral ischemia in rats. ( Chen, ZQ; Jiang, ZL; Li, X; Peng, LL; Wang, GH, 2010) |
| "Infarct volume following middle cerebral artery occlusion is dramatically diminished in several regions of the brains of SR mutant mice despite evidence of increased NMDA receptor number and sensitivity." | 5.36 | Serine racemase deletion protects against cerebral ischemia and excitotoxicity. ( Ahmad, AS; Barrow, RK; Coyle, JT; Doré, S; Ehmsen, JT; Gazi, SK; Mustafa, AK; Sikka, G; Snyder, SH; Zeynalov, E, 2010) |
| "To investigate the neuroprotective effect of L-serine and its underlying mechanisms, focal cerebral ischemia was induced in rats by occlusion of middle cerebral artery (MCAO) with a suture, and reperfusion was given by filament withdrawal 2 hr later." | 3.76 | Neuroprotective effect of L-serine against temporary cerebral ischemia in rats. ( Chen, ZQ; Jiang, ZL; Li, X; Peng, LL; Wang, GH, 2010) |
| "Infarct volume following middle cerebral artery occlusion is dramatically diminished in several regions of the brains of SR mutant mice despite evidence of increased NMDA receptor number and sensitivity." | 1.36 | Serine racemase deletion protects against cerebral ischemia and excitotoxicity. ( Ahmad, AS; Barrow, RK; Coyle, JT; Doré, S; Ehmsen, JT; Gazi, SK; Mustafa, AK; Sikka, G; Snyder, SH; Zeynalov, E, 2010) |
| "Upon transient middle cerebral artery occlusion for 90 min and 24 h of reperfusion, infarct volume and number of ATF-2-, TUNEL- and cleaved Caspase-3-positive cells were determined in conditional c-Jun knock-out mice (cond." | 1.34 | Infarct volume after transient middle cerebral artery occlusion (MCAo) can be reduced by attenuation but not by inactivation of c-Jun action. ( Behrens, A; Schenkel, J; Schorpp-Kistner, M; Vogel, J; Wagner, EF; Weigand, MA; Zimmermann, M, 2007) |
| "At early stage after middle cerebral artery occlusion (MCAO), no significant change in expression of serine racemase was observed in temporoparietal cortex in ipsilateral hemisphere." | 1.32 | Serine racemase expression in mouse cerebral cortex after permanent focal cerebral ischemia. ( Wang, LZ; Zhu, XZ, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 8 (72.73) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hirt, L | 1 |
| Price, M | 1 |
| Mastour, N | 1 |
| Brunet, JF | 1 |
| Barrière, G | 1 |
| Friscourt, F | 1 |
| Badaut, J | 1 |
| Ren, TJ | 2 |
| Qiang, R | 2 |
| Jiang, ZL | 3 |
| Wang, GH | 3 |
| Sun, L | 2 |
| Jiang, R | 2 |
| Zhao, GW | 2 |
| Han, LY | 1 |
| Zhou, H | 1 |
| Zhang, Z | 1 |
| Wei, H | 1 |
| Wang, F | 1 |
| Guo, F | 1 |
| Gao, Z | 1 |
| Marsicano, G | 1 |
| Wang, Q | 1 |
| Xiong, L | 1 |
| Yang, Y | 1 |
| Xu, LH | 1 |
| Abe, T | 1 |
| Suzuki, M | 1 |
| Sasabe, J | 1 |
| Takahashi, S | 1 |
| Unekawa, M | 1 |
| Mashima, K | 1 |
| Iizumi, T | 1 |
| Hamase, K | 1 |
| Konno, R | 1 |
| Aiso, S | 1 |
| Suzuki, N | 1 |
| Li, L | 1 |
| Zhi, D | 1 |
| Shen, Y | 1 |
| Liu, K | 1 |
| Li, H | 1 |
| Chen, J | 1 |
| Mustafa, AK | 1 |
| Ahmad, AS | 1 |
| Zeynalov, E | 1 |
| Gazi, SK | 1 |
| Sikka, G | 1 |
| Ehmsen, JT | 1 |
| Barrow, RK | 1 |
| Coyle, JT | 1 |
| Snyder, SH | 1 |
| Doré, S | 1 |
| Chen, ZQ | 1 |
| Li, X | 1 |
| Peng, LL | 1 |
| Wang, LZ | 1 |
| Zhu, XZ | 1 |
| Brecht, S | 1 |
| Kirchhof, R | 1 |
| Chromik, A | 1 |
| Willesen, M | 1 |
| Nicolaus, T | 1 |
| Raivich, G | 1 |
| Wessig, J | 1 |
| Waetzig, V | 1 |
| Goetz, M | 1 |
| Claussen, M | 1 |
| Pearse, D | 1 |
| Kuan, CY | 1 |
| Vaudano, E | 1 |
| Behrens, A | 2 |
| Wagner, E | 1 |
| Flavell, RA | 1 |
| Davis, RJ | 1 |
| Herdegen, T | 1 |
| Vogel, J | 1 |
| Weigand, MA | 1 |
| Wagner, EF | 1 |
| Schorpp-Kistner, M | 1 |
| Zimmermann, M | 1 |
| Schenkel, J | 1 |
11 other studies available for serine and Infarction, Middle Cerebral Artery
| Article | Year |
|---|---|
Increase of aquaporin 9 expression in astrocytes participates in astrogliosis.
Topics: Animals; Aquaporin 4; Aquaporins; Astrocytes; Cells, Cultured; Disease Models, Animal; Embryo, Mamma | 2018 |
Improvement in regional CBF by L-serine contributes to its neuroprotective effect in rats after focal cerebral ischemia.
Topics: Animals; Apamin; Cerebrovascular Circulation; Charybdotoxin; Dose-Response Relationship, Drug; Drug | 2013 |
Activation of STAT3 is involved in neuroprotection by electroacupuncture pretreatment via cannabinoid CB1 receptors in rats.
Topics: Animals; Apoptosis; Caspase 3; Disease Models, Animal; Electroacupuncture; Functional Laterality; In | 2013 |
L-serine treatment may improve neurorestoration of rats after permanent focal cerebral ischemia potentially through improvement of neurorepair.
Topics: Animals; Cell Proliferation; Central Nervous System Agents; Cerebral Cortex; Cerebrovascular Circula | 2014 |
Cellular origin and regulation of D- and L-serine in in vitro and in vivo models of cerebral ischemia.
Topics: Animals; Animals, Newborn; Astrocytes; Brain Ischemia; Disease Models, Animal; Female; Humans; Infar | 2014 |
Effects of CC-chemokine receptor 5 on ROCK2 and P-MLC2 expression after focal cerebral ischaemia-reperfusion injury in rats.
Topics: Analysis of Variance; Animals; Brain Infarction; Cardiac Myosins; Disease Models, Animal; In Situ Ni | 2016 |
Serine racemase deletion protects against cerebral ischemia and excitotoxicity.
Topics: Animals; Brain; Brain Infarction; Brain Ischemia; Cells, Cultured; Cytoprotection; Disease Models, A | 2010 |
Neuroprotective effect of L-serine against temporary cerebral ischemia in rats.
Topics: Animals; Brain; Brain Ischemia; Cell Hypoxia; Cells, Cultured; Dose-Response Relationship, Drug; Glu | 2010 |
Serine racemase expression in mouse cerebral cortex after permanent focal cerebral ischemia.
Topics: Animals; Cerebral Cortex; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred C57BL; Racema | 2004 |
Specific pathophysiological functions of JNK isoforms in the brain.
Topics: Animals; Autonomic Denervation; Behavior, Animal; Blotting, Western; Brain; Brain Injuries; Cell Cou | 2005 |
Infarct volume after transient middle cerebral artery occlusion (MCAo) can be reduced by attenuation but not by inactivation of c-Jun action.
Topics: Activating Transcription Factor 2; Analysis of Variance; Animals; Caspase 3; In Situ Nick-End Labeli | 2007 |