serine has been researched along with Hypoglycemia in 11 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Hypoglycemia: A syndrome of abnormally low BLOOD GLUCOSE level. Clinical hypoglycemia has diverse etiologies. Severe hypoglycemia eventually lead to glucose deprivation of the CENTRAL NERVOUS SYSTEM resulting in HUNGER; SWEATING; PARESTHESIA; impaired mental function; SEIZURES; COMA; and even DEATH.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The effect of pregnancy on the glycemic response to exogenous alanine administration during starvation was also investigated." | 3.65 | Amino acid metabolism during starvation in human pregnancy. ( Felig, P; Hendler, R; Kim, YJ; Lynch, V, 1972) |
| "We exposed human umbilical vein endothelial cells to low glucose conditions in a clinically relevant range (40-70 mg/dL) and found rapid and marked reductions in nitric oxide (NO) bioavailability (P<0." | 1.38 | Acute exposure to low glucose rapidly induces endothelial dysfunction and mitochondrial oxidative stress: role for AMP kinase. ( Alexanian, A; Dharmashankar, K; Gutterman, DD; Kizhakekuttu, TJ; Vasquez-Vivar, J; Wang, J; Widlansky, ME; Ying, R, 2012) |
| "Glycine was partially effective in alleviating the growth depression caused by excess methionine." | 1.25 | Methionine toxicity in the chick: nutritional and metabolic implications. ( Baker, DH; Katz, RS, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (63.64) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Senthilkumaran, M | 1 |
| Bobrovskaya, L | 1 |
| Shimazu, J | 1 |
| Wei, J | 1 |
| Karsenty, G | 1 |
| Wang, J | 1 |
| Alexanian, A | 1 |
| Ying, R | 1 |
| Kizhakekuttu, TJ | 1 |
| Dharmashankar, K | 1 |
| Vasquez-Vivar, J | 1 |
| Gutterman, DD | 1 |
| Widlansky, ME | 1 |
| RIESER, P | 1 |
| KNAUFF, HG | 1 |
| MARX, D | 1 |
| MAYER, G | 1 |
| Teng, MN | 1 |
| Borrow, P | 1 |
| Oldstone, MB | 1 |
| de la Torre, JC | 1 |
| Katz, RS | 1 |
| Baker, DH | 1 |
| Bergman, EN | 1 |
| Kaufman, CF | 1 |
| Wolff, JE | 1 |
| Williams, HH | 1 |
| Stone, WE | 1 |
| Tews, JK | 1 |
| Whisler, KE | 1 |
| Brown, DJ | 1 |
| Felig, P | 1 |
| Kim, YJ | 1 |
| Lynch, V | 1 |
| Hendler, R | 1 |
| Metzger, BE | 1 |
| Hare, JW | 1 |
| Freinkel, N | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Impact on the Oxidative Stress of the Different Analogues of Insulin in People With Type 1 Diabetes. Clinical Trial of Low Level of Intervention. (Ineox Study)[NCT03328845] | Phase 4 | 300 participants (Actual) | Interventional | 2017-01-20 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
11 other studies available for serine and Hypoglycemia
| Article | Year |
|---|---|
The effects of recurrent hypoglycaemia and opioid antagonists on the adrenal catecholamine synthetic capacity in a rat model of HAAF.
Topics: Animals; Blood Glucose; Disease Models, Animal; Epinephrine; Hypoglycemia; Hypoglycemic Agents; Insu | 2018 |
Smurf1 Inhibits Osteoblast Differentiation, Bone Formation, and Glucose Homeostasis through Serine 148.
Topics: Animals; Cell Differentiation; Cells, Cultured; Core Binding Factor Alpha 1 Subunit; Glucose; Homeos | 2016 |
Acute exposure to low glucose rapidly induces endothelial dysfunction and mitochondrial oxidative stress: role for AMP kinase.
Topics: Adipose Tissue; AMP-Activated Protein Kinases; Antioxidants; Arterioles; Cells, Cultured; Endotheliu | 2012 |
ENZYMATIC HYPOGLYCEMIA IN ALLOXAN DIABETIC RATS.
Topics: Alloxan; Animals; Chymotrypsin; Diabetes Mellitus, Experimental; Histidine; Hypoglycemia; Pharmacolo | 1965 |
[The behavior of proteins and serine- and colamine-containing phosphatides of the central nervous system during insulin hypoglycemia].
Topics: Amino Alcohols; Brain; Brain Chemistry; Central Nervous System; Ethanolamine; Hypoglycemia; Insulin; | 1961 |
A single amino acid change in the glycoprotein of lymphocytic choriomeningitis virus is associated with the ability to cause growth hormone deficiency syndrome.
Topics: Animals; Cell Line; Cricetinae; Genetic Variation; Glycoproteins; Growth Disorders; Hypoglycemia; Ly | 1996 |
Methionine toxicity in the chick: nutritional and metabolic implications.
Topics: Adenine; Amino Acids; Animals; Arginine; Blood Glucose; Body Weight; Chickens; Glycine; Hypoglycemia | 1975 |
Renal metabolism of amino acids and ammonia in fed and fasted pregnant sheep.
Topics: Acidosis; Alanine; Amino Acids; Ammonia; Animals; Arginine; Aspartic Acid; Catheterization; Citrulli | 1974 |
Incorporation of carbon from glucose into cerebral amino acids, proteins and lipids, and alterations during recovery from hypoglycaemia.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Blood Glucose; Carbon Isotopes; Cerebr | 1972 |
Amino acid metabolism during starvation in human pregnancy.
Topics: Adolescent; Adult; Alanine; Amino Acids; Aminobutyrates; Amniotic Fluid; Blood Glucose; Female; Food | 1972 |
Carbohydrate metabolism in pregnancy. IX. Plasma levels of gluconeogenic fuels during fasting in the rat.
Topics: Alanine; Amino Acids; Animals; Carbohydrate Metabolism; Fasting; Female; Gluconeogenesis; Glutamates | 1971 |