Page last updated: 2024-11-08

serine and Hyperplasia

serine has been researched along with Hyperplasia in 5 studies

Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.

Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.

Research Excerpts

ExcerptRelevanceReference
" Uteroplacental insufficiency significantly decreased serine-15-phosphorylated (serine-15P) p53, an active form of p53, in IUGR rat lung."7.74Uteroplacental insufficiency decreases p53 serine-15 phosphorylation in term IUGR rat lungs. ( Albertine, KH; Barnes, V; Callaway, CW; Dahl, MJ; Lane, RH; McIntyre, TM; McKnight, RA; O'Brien, EA; Sun, JC; Wang, L; Wang, Z; Wint, A; Yu, X; Zhao, L, 2007)
"Azaserine was selected because it behaves as a direct-acting mutagen in two bacterial test systems and because tissue distribution studies showed concentration especially in kidney and pancreas."5.25Adenocarcinoma of the pancreas in azaserine-treated rats. ( Curphey, TJ; Longnecker, DS, 1975)
" Uteroplacental insufficiency significantly decreased serine-15-phosphorylated (serine-15P) p53, an active form of p53, in IUGR rat lung."3.74Uteroplacental insufficiency decreases p53 serine-15 phosphorylation in term IUGR rat lungs. ( Albertine, KH; Barnes, V; Callaway, CW; Dahl, MJ; Lane, RH; McIntyre, TM; McKnight, RA; O'Brien, EA; Sun, JC; Wang, L; Wang, Z; Wint, A; Yu, X; Zhao, L, 2007)
"Azaserine was selected because it behaves as a direct-acting mutagen in two bacterial test systems and because tissue distribution studies showed concentration especially in kidney and pancreas."1.25Adenocarcinoma of the pancreas in azaserine-treated rats. ( Curphey, TJ; Longnecker, DS, 1975)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fan, CF1
Mao, XY1
Wang, EH1
Kim, SS1
Cao, L1
Li, C1
Xu, X1
Huber, LJ1
Chodosh, LA1
Deng, CX1
Umar, S1
Wang, Y1
Morris, AP1
Sellin, JH1
O'Brien, EA1
Barnes, V1
Zhao, L1
McKnight, RA1
Yu, X1
Callaway, CW1
Wang, L1
Sun, JC1
Dahl, MJ1
Wint, A1
Wang, Z1
McIntyre, TM1
Albertine, KH1
Lane, RH1
Longnecker, DS1
Curphey, TJ1

Other Studies

5 other studies available for serine and Hyperplasia

ArticleYear
Elevated p-CREB-2 (ser 245) expression is potentially associated with carcinogenesis and development of breast carcinoma.
    Molecular medicine reports, 2012, Volume: 5, Issue:2

    Topics: Activating Transcription Factor 4; Adolescent; Adult; Aged; Breast Neoplasms; Cell Line, Tumor; Fema

2012
Uterus hyperplasia and increased carcinogen-induced tumorigenesis in mice carrying a targeted mutation of the Chk2 phosphorylation site in Brca1.
    Molecular and cellular biology, 2004, Volume: 24, Issue:21

    Topics: Aging; Animals; BRCA1 Protein; Carcinogens; Cell Cycle; Cell Transformation, Neoplastic; Checkpoint

2004
Dual alterations in casein kinase I-epsilon and GSK-3beta modulate beta-catenin stability in hyperproliferating colonic epithelia.
    American journal of physiology. Gastrointestinal and liver physiology, 2007, Volume: 292, Issue:2

    Topics: Animals; Axin Protein; beta Catenin; Boronic Acids; Bortezomib; Casein Kinase 1 epsilon; Cell Nucleu

2007
Uteroplacental insufficiency decreases p53 serine-15 phosphorylation in term IUGR rat lungs.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2007, Volume: 293, Issue:1

    Topics: Animals; Animals, Newborn; Apoptosis; Blotting, Western; Cell Cycle; Female; Fetal Growth Retardatio

2007
Adenocarcinoma of the pancreas in azaserine-treated rats.
    Cancer research, 1975, Volume: 35, Issue:8

    Topics: Adenocarcinoma; Adenoma; Animals; Azaserine; Dipeptides; Disease Models, Animal; Hyperplasia; Inject

1975