Page last updated: 2024-11-08

serine and Hyperlipemia

serine has been researched along with Hyperlipemia in 13 studies

Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
"A mutation in the lipoprotein lipase (LPL) gene, resulting in the substitution of asparagine by serine at residue 291 (LPL-S291), was found to occur in young survivors of a myocardial infarction from Sweden, combined hyperlipidemic subjects from the United Kingdom, and type III hyperlipidemic subjects from Germany at allelic carrier frequencies no different from those found in companion healthy control subjects (3."7.69Interaction of the lipoprotein lipase asparagine 291-->serine mutation with body mass index determines elevated plasma triacylglycerol concentrations: a study in hyperlipidemic subjects, myocardial infarction survivors, and healthy adults. ( Beisiegel, U; Feussner, G; Fisher, RM; Hamsten, A; Humphries, SE; Mailly, F; Miller, G; Peacock, RE; Seed, M; Yudkin, JS, 1995)
"However, treatment of hyperlipidemia with statins reduces the probability of a CV event."5.34Receptor for advanced glycation end products Glycine 82 Serine polymorphism and risk of cardiovascular events in rheumatoid arthritis. ( Carroll, L; Frazer, IH; Marwick, TH; Thomas, R; Turner, M, 2007)
"A mutation in the lipoprotein lipase (LPL) gene, resulting in the substitution of asparagine by serine at residue 291 (LPL-S291), was found to occur in young survivors of a myocardial infarction from Sweden, combined hyperlipidemic subjects from the United Kingdom, and type III hyperlipidemic subjects from Germany at allelic carrier frequencies no different from those found in companion healthy control subjects (3."3.69Interaction of the lipoprotein lipase asparagine 291-->serine mutation with body mass index determines elevated plasma triacylglycerol concentrations: a study in hyperlipidemic subjects, myocardial infarction survivors, and healthy adults. ( Beisiegel, U; Feussner, G; Fisher, RM; Hamsten, A; Humphries, SE; Mailly, F; Miller, G; Peacock, RE; Seed, M; Yudkin, JS, 1995)
"However, treatment of hyperlipidemia with statins reduces the probability of a CV event."1.34Receptor for advanced glycation end products Glycine 82 Serine polymorphism and risk of cardiovascular events in rheumatoid arthritis. ( Carroll, L; Frazer, IH; Marwick, TH; Thomas, R; Turner, M, 2007)
"Insulin resistance was estimated using the homeostasis model assessment (HOMA) index."1.31Interaction between the Asn291Ser variant of the LPL gene and insulin resistance on dyslipidaemia in high risk individuals for Type 2 diabetes mellitus. ( Groop, L; Klannemark, M; Orho-Melander, M; Suurinkeroinen, L; Taskinen, MR, 2000)
" Therefore, we investigated whether endothelial dysfunction and/or vascular NO bioavailability is reflected by decreased vessel wall P-VASP and whether improvement of endothelial dysfunction restores this P-VASP."1.31Vasodilator-stimulated phosphoprotein serine 239 phosphorylation as a sensitive monitor of defective nitric oxide/cGMP signaling and endothelial dysfunction. ( Bodenschatz, M; Hoffmann, N; Meinertz, T; Mollnau, H; Münzel, T; Oelze, M; Skatchkov, M; Smolenski, A; Walter, U; Warnholtz, A, 2000)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19905 (38.46)18.7374
1990's2 (15.38)18.2507
2000's3 (23.08)29.6817
2010's2 (15.38)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Wei, X1
Jia, X1
Liu, R1
Zhang, S1
Liu, S1
An, J1
Zhou, L1
Zhang, Y1
Mo, Y1
Li, X1
Hayne, CK1
Lafferty, MJ1
Eglinger, BJ1
Kane, JP1
Neher, SB1
Reimann, M1
Peitzsch, M1
Ziemssen, T1
Julius, U1
Eisenhofer, G1
Carroll, L1
Frazer, IH1
Turner, M1
Marwick, TH1
Thomas, R1
Fisher, RM1
Mailly, F1
Peacock, RE1
Hamsten, A1
Seed, M1
Yudkin, JS1
Beisiegel, U1
Feussner, G1
Miller, G1
Humphries, SE1
Klannemark, M1
Suurinkeroinen, L1
Orho-Melander, M1
Groop, L1
Taskinen, MR2
Oelze, M1
Mollnau, H1
Hoffmann, N1
Warnholtz, A1
Bodenschatz, M1
Smolenski, A1
Walter, U1
Skatchkov, M1
Meinertz, T1
Münzel, T1
Shulman, RS1
Herbert, PN1
Wehrly, K2
Fredrickson, DS1
Amit, N1
Ayrault-Jarrier, M1
Davril, M1
Han, KK1
Tenkanen, H1
Koskinen, P1
Metso, J1
Baumann, M1
Lukka, M1
Kauppinen-Mäkelin, R1
Kontula, K1
Mänttäri, M1
Manninen, V1
Jackson, RL2
Morrisett, JD2
Sparrow, JT2
Segrest, JP1
Pownall, HJ1
Smith, LC1
Hoff, HF1
Gotto, AM2
Baker, HN1
Taunton, OD1
Brewer, HB1
Shulman, R1
Herbert, P1
Ronan, R1

Other Studies

13 other studies available for serine and Hyperlipemia

ArticleYear
Metabolic pathway analysis of hyperuricaemia patients with hyperlipidaemia based on high-throughput mass spectrometry: a case‒control study.
    Lipids in health and disease, 2022, Dec-31, Volume: 21, Issue:1

    Topics: Alanine; Aspartic Acid; Biomarkers; Case-Control Studies; Glycine; Humans; Hyperlipidemias; Hyperuri

2022
Biochemical Analysis of the Lipoprotein Lipase Truncation Variant, LPL
    Biochemistry, 2017, 01-24, Volume: 56, Issue:3

    Topics: Angiopoietin-Like Protein 4; Angiopoietins; Animals; Biological Transport; Cholesterol, HDL; Cholest

2017
Metabolomic distinction of microvascular effects of lipoprotein apheresis--a pilot study.
    Atherosclerosis. Supplements, 2013, Volume: 14, Issue:1

    Topics: Adult; Aged; Biomarkers; Blood Component Removal; Carnitine; Chi-Square Distribution; Decision Trees

2013
Receptor for advanced glycation end products Glycine 82 Serine polymorphism and risk of cardiovascular events in rheumatoid arthritis.
    Arthritis research & therapy, 2007, Volume: 9, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Cardiovascular Diseases; Genetic

2007
Interaction of the lipoprotein lipase asparagine 291-->serine mutation with body mass index determines elevated plasma triacylglycerol concentrations: a study in hyperlipidemic subjects, myocardial infarction survivors, and healthy adults.
    Journal of lipid research, 1995, Volume: 36, Issue:10

    Topics: Adolescent; Adult; Aged; Amino Acid Sequence; Arginine; Base Sequence; Body Mass Index; Case-Control

1995
Interaction between the Asn291Ser variant of the LPL gene and insulin resistance on dyslipidaemia in high risk individuals for Type 2 diabetes mellitus.
    Diabetic medicine : a journal of the British Diabetic Association, 2000, Volume: 17, Issue:8

    Topics: Aged; Amino Acid Substitution; Apolipoproteins; Asparagine; Blood Pressure; Cholesterol; Cholesterol

2000
Vasodilator-stimulated phosphoprotein serine 239 phosphorylation as a sensitive monitor of defective nitric oxide/cGMP signaling and endothelial dysfunction.
    Circulation research, 2000, Nov-24, Volume: 87, Issue:11

    Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta; Biphenyl Compounds; Cell

2000
Thf complete amino acid sequence of C-I (apoLp-Ser), an apolipoprotein from human very low density lipoproteins.
    The Journal of biological chemistry, 1975, Jan-10, Volume: 250, Issue:1

    Topics: Amino Acid Sequence; Amino Acids; Aminopeptidases; Apoproteins; Carboxypeptidases; Chromatography, D

1975
Evidence for the presence of serine-protease in the preparation of the very low density lipoproteins in human plasma.
    Biochimie, 1978, Sep-04, Volume: 60, Issue:5

    Topics: Humans; Hyperlipidemias; Lipoproteins, VLDL; Peptide Hydrolases; Serine

1978
A novel polymorphism of apolipoprotein A-IV is the result of an asparagine to serine substitution at residue 127.
    Biochimica et biophysica acta, 1992, Jan-16, Volume: 1138, Issue:1

    Topics: Alleles; Amino Acid Sequence; Apolipoproteins A; Asparagine; Base Sequence; Cholesterol; Codon; Geno

1992
The interaction of apolipoprotein-serine with phosphatidylcholine.
    The Journal of biological chemistry, 1974, Aug-25, Volume: 249, Issue:16

    Topics: Amino Acid Sequence; Apoproteins; Binding Sites; Carbon Radioisotopes; Chromatography, DEAE-Cellulos

1974
The primary structure of apolopoprotein-serine.
    The Journal of biological chemistry, 1974, Aug-25, Volume: 249, Issue:16

    Topics: Amino Acid Sequence; Amino Acids; Aminopeptidases; Animals; Apoproteins; Carboxypeptidases; Chromato

1974
The complete amino acid sequence of alanine apolipoprotein (apoC-3), and apolipoprotein from human plasma very low density lipoproteins.
    The Journal of biological chemistry, 1974, Aug-10, Volume: 249, Issue:15

    Topics: Alanine; Amino Acid Sequence; Amino Acids; Apoproteins; Chromatography, Gas; Chromatography, Thin La

1974