serine has been researched along with Hepatitis B Virus Infection in 8 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phosphorylation of serines 157, 164, and 172 within the carboxyl-terminal SPRRR motif of the hepatitis B virus (HBV) core (C) protein modulates HBV replication at multiple stages." | 7.80 | Phosphoacceptors threonine 162 and serines 170 and 178 within the carboxyl-terminal RRRS/T motif of the hepatitis B virus core protein make multiple contributions to hepatitis B virus replication. ( Chwae, YJ; Hwang, SG; Jung, J; Kim, K; Park, S; Shin, HJ, 2014) |
| " Hepatitis B virus (HBV) is the most common etiologic agent in HCC, and its encoded X-protein (HBx) is oncogenic and possesses a serine-proline motif that may bind Pin1." | 7.74 | Pin1 interacts with a specific serine-proline motif of hepatitis B virus X-protein to enhance hepatocarcinogenesis. ( Fan, ST; Kwong, YL; Lee, TK; Pang, R; Poon, RT; Tse, E; Wong, KB, 2007) |
| "Hepatocellular carcinoma is mainly associated with viral hepatitis B and C." | 5.37 | Serine 204 phosphorylation and O-β-GlcNAC interplay of IGFBP-6 as therapeutic indicator to regulate IGF-II functions in viral mediated hepatocellular carcinoma. ( Ahmad, W; Asad, S; Fouzia, K; Gull, S; Hassan, S; Ijaz, B; Kausar, H; Nazar, N; Nazar, S; Sarwar, MT; Shabbiri, K; Shahid, I, 2011) |
| "Phosphorylation of serines 157, 164, and 172 within the carboxyl-terminal SPRRR motif of the hepatitis B virus (HBV) core (C) protein modulates HBV replication at multiple stages." | 3.80 | Phosphoacceptors threonine 162 and serines 170 and 178 within the carboxyl-terminal RRRS/T motif of the hepatitis B virus core protein make multiple contributions to hepatitis B virus replication. ( Chwae, YJ; Hwang, SG; Jung, J; Kim, K; Park, S; Shin, HJ, 2014) |
| " Hepatitis B virus (HBV) is the most common etiologic agent in HCC, and its encoded X-protein (HBx) is oncogenic and possesses a serine-proline motif that may bind Pin1." | 3.74 | Pin1 interacts with a specific serine-proline motif of hepatitis B virus X-protein to enhance hepatocarcinogenesis. ( Fan, ST; Kwong, YL; Lee, TK; Pang, R; Poon, RT; Tse, E; Wong, KB, 2007) |
| "A selective mutation, an arginine-to-serine substitution in codon 249, of the p53 gene has been identified as a "hotspot" mutation in hepatocellular carcinoma (HCC)." | 3.70 | Ser-249 p53 mutations in plasma DNA of patients with hepatocellular carcinoma from The Gambia. ( Bréchot, C; Camus-Randon, AM; Goedert, JJ; Hainaut, P; Kirk, GD; Mendy, M; Merle, P; Montesano, R; Trépo, C, 2000) |
| "Hepatocellular carcinoma is mainly associated with viral hepatitis B and C." | 1.37 | Serine 204 phosphorylation and O-β-GlcNAC interplay of IGFBP-6 as therapeutic indicator to regulate IGF-II functions in viral mediated hepatocellular carcinoma. ( Ahmad, W; Asad, S; Fouzia, K; Gull, S; Hassan, S; Ijaz, B; Kausar, H; Nazar, N; Nazar, S; Sarwar, MT; Shabbiri, K; Shahid, I, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jung, J | 1 |
| Hwang, SG | 1 |
| Chwae, YJ | 1 |
| Park, S | 1 |
| Shin, HJ | 1 |
| Kim, K | 1 |
| Ahmad, W | 1 |
| Shabbiri, K | 1 |
| Ijaz, B | 1 |
| Asad, S | 1 |
| Nazar, N | 1 |
| Nazar, S | 1 |
| Fouzia, K | 1 |
| Kausar, H | 1 |
| Gull, S | 1 |
| Sarwar, MT | 1 |
| Shahid, I | 1 |
| Hassan, S | 1 |
| Tang, J | 1 |
| Zhang, ZH | 1 |
| Huang, M | 1 |
| Heise, T | 1 |
| Zhang, J | 1 |
| Liu, GL | 1 |
| Enomoto, M | 1 |
| Sawano, Y | 1 |
| Kosuge, S | 1 |
| Yamano, Y | 1 |
| Kuroki, K | 1 |
| Ohtsuki, K | 1 |
| Pang, R | 1 |
| Lee, TK | 1 |
| Poon, RT | 1 |
| Fan, ST | 1 |
| Wong, KB | 1 |
| Kwong, YL | 1 |
| Tse, E | 1 |
| Shi, Y | 1 |
| Li, J | 1 |
| Liang, LC | 1 |
| Wu, YS | 1 |
| Zhou, YS | 1 |
| Chen, XY | 1 |
| Chen, DX | 1 |
| Wu, H | 2 |
| Ghebranious, N | 1 |
| Knoll, BJ | 1 |
| Lozano, G | 1 |
| Sell, S | 1 |
| Kirk, GD | 1 |
| Camus-Randon, AM | 1 |
| Mendy, M | 1 |
| Goedert, JJ | 1 |
| Merle, P | 1 |
| Trépo, C | 1 |
| Bréchot, C | 1 |
| Hainaut, P | 1 |
| Montesano, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot Study of Changes in Circulating Tumor-Specific DNA (ctDNA) in Patients With Non-Metastatic Non-Small Cell Lung Cancer[NCT03746262] | 40 participants (Actual) | Observational | 2016-05-13 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 other studies available for serine and Hepatitis B Virus Infection
| Article | Year |
|---|---|
Phosphoacceptors threonine 162 and serines 170 and 178 within the carboxyl-terminal RRRS/T motif of the hepatitis B virus core protein make multiple contributions to hepatitis B virus replication.
Topics: Amino Acid Motifs; Amino Acid Sequence; Cell Line, Tumor; DNA Replication; DNA, Viral; Genome, Viral | 2014 |
Serine 204 phosphorylation and O-β-GlcNAC interplay of IGFBP-6 as therapeutic indicator to regulate IGF-II functions in viral mediated hepatocellular carcinoma.
Topics: Acetylglucosamine; Amino Acid Sequence; Carcinoma, Hepatocellular; Glycosylation; Hepacivirus; Hepat | 2011 |
Phosphorylation of human La protein at Ser 366 by casein kinase II contributes to hepatitis B virus replication and expression in vitro.
Topics: Adolescent; Adult; Aged; Benzimidazoles; Casein Kinase II; Cell Line, Tumor; Dose-Response Relations | 2013 |
High phosphorylation of HBV core protein by two alpha-type CK2-activated cAMP-dependent protein kinases in vitro.
Topics: Animals; Antineoplastic Agents; Casein Kinase II; Cattle; Cyclic AMP; Cyclic AMP-Dependent Protein K | 2006 |
Pin1 interacts with a specific serine-proline motif of hepatitis B virus X-protein to enhance hepatocarcinogenesis.
Topics: Amino Acid Motifs; Animals; bcl-X Protein; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Prolife | 2007 |
[Expression of K18, Ser-33 and Ser-52 phosphorylated K18 in HBV infected human liver disease and its significance].
Topics: Hepatitis B; Humans; Immunohistochemistry; Keratin-18; Liver Cirrhosis; Liver Diseases; Phosphorylat | 2007 |
Characterization of a murine p53ser246 mutant equivalent to the human p53ser249 associated with hepatocellular carcinoma and aflatoxin exposure.
Topics: Aflatoxin B1; Amino Acid Sequence; Animals; Arginine; Base Sequence; Carcinoma, Hepatocellular; Codo | 1995 |
Ser-249 p53 mutations in plasma DNA of patients with hepatocellular carcinoma from The Gambia.
Topics: Adult; Aflatoxins; Aged; Aged, 80 and over; Arginine; Black People; Carcinoma, Hepatocellular; Case- | 2000 |