serine has been researched along with Heart Disease, Ischemic in 13 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Leonurine has been shown to have excellent anti-myocardial ischemia effects." | 8.12 | Cardioprotective Mechanism of Leonurine against Myocardial Ischemia through a Liver-Cardiac Crosstalk Metabolomics Study. ( Li, J; Lu, Q; Pan, D; Rong, W; Wang, A; Wang, L; Zhang, Y; Zhou, Q; Zhu, Q; Zhu, Y, 2022) |
| "Leonurine has been shown to have excellent anti-myocardial ischemia effects." | 4.12 | Cardioprotective Mechanism of Leonurine against Myocardial Ischemia through a Liver-Cardiac Crosstalk Metabolomics Study. ( Li, J; Lu, Q; Pan, D; Rong, W; Wang, A; Wang, L; Zhang, Y; Zhou, Q; Zhu, Q; Zhu, Y, 2022) |
| " Male Wistar rats (weighing 300-350 g) were assigned to the following groups: (1) sham, (2) myocardial ischemia vehicle-treated (MI-V), and (3) myocardial ischemia clofibrate-treated." | 3.81 | PPARα Stimulation Modulates Myocardial Ischemia-induced Activation of Renin-Angiotensin System. ( Cervantes-Pérez, LG; del Valle-Mondragón, L; Hong, E; Ibarra-Lara, L; Pastelín-Hernández, GS; Pérez-Severiano, F; Ramírez-Ortega, M; Sánchez-Aguilar, M; Sánchez-Mendoza, A; Soria-Castro, E; Torres-Narváez, JC, 2015) |
| "Treatment with rotigaptide significantly increased the time to ischemia-induced asystole and suppressed dephosphorylation of Ser297 and Ser368 at 30 min of ischemia." | 1.33 | Identification of ischemia-regulated phosphorylation sites in connexin43: A possible target for the antiarrhythmic peptide analogue rotigaptide (ZP123). ( Andersen, S; Axelsen, LN; Hennan, JK; Holstein-Rathlou, NH; Jensen, ON; Kjølbye, AL; Larsen, BD; Mohammed, S; Nielsen, MS; Stahlhut, M, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 6 (46.15) | 29.6817 |
| 2010's | 5 (38.46) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Rong, W | 1 |
| Li, J | 1 |
| Pan, D | 1 |
| Zhou, Q | 1 |
| Zhang, Y | 2 |
| Lu, Q | 1 |
| Wang, L | 1 |
| Wang, A | 1 |
| Zhu, Y | 1 |
| Zhu, Q | 1 |
| Tang, B | 1 |
| Ma, J | 1 |
| Ha, X | 1 |
| Xing, Y | 1 |
| Ibarra-Lara, L | 1 |
| Sánchez-Aguilar, M | 1 |
| Hong, E | 1 |
| del Valle-Mondragón, L | 1 |
| Soria-Castro, E | 1 |
| Pérez-Severiano, F | 1 |
| Torres-Narváez, JC | 1 |
| Ramírez-Ortega, M | 1 |
| Pastelín-Hernández, GS | 1 |
| Cervantes-Pérez, LG | 1 |
| Sánchez-Mendoza, A | 1 |
| Borai, A | 1 |
| Livingstone, C | 1 |
| Ghayour-Mobarhan, M | 1 |
| Abuosa, A | 1 |
| Shafi, S | 1 |
| Mehta, S | 1 |
| Heidari, A | 1 |
| Emadzadeh, A | 1 |
| Wark, G | 1 |
| Ferns, G | 1 |
| Lv, L | 1 |
| Jiang, SS | 1 |
| Xu, J | 1 |
| Gong, JB | 1 |
| Cheng, Y | 1 |
| Respress, JL | 1 |
| van Oort, RJ | 1 |
| Li, N | 1 |
| Rolim, N | 1 |
| Dixit, SS | 1 |
| deAlmeida, A | 1 |
| Voigt, N | 1 |
| Lawrence, WS | 1 |
| Skapura, DG | 1 |
| Skårdal, K | 1 |
| Wisløff, U | 1 |
| Wieland, T | 1 |
| Ai, X | 1 |
| Pogwizd, SM | 1 |
| Dobrev, D | 1 |
| Wehrens, XH | 1 |
| Shi, Y | 1 |
| Baker, JE | 1 |
| Zhang, C | 1 |
| Tweddell, JS | 1 |
| Su, J | 1 |
| Pritchard, KA | 1 |
| Bonafé, M | 1 |
| Salvioli, S | 1 |
| Barbi, C | 1 |
| Trapassi, C | 1 |
| Tocco, F | 1 |
| Storci, G | 1 |
| Invidia, L | 1 |
| Vannini, I | 1 |
| Rossi, M | 1 |
| Marzi, E | 1 |
| Mishto, M | 1 |
| Capri, M | 1 |
| Olivieri, F | 1 |
| Antonicelli, R | 1 |
| Memo, M | 1 |
| Uberti, D | 1 |
| Nacmias, B | 1 |
| Sorbi, S | 1 |
| Monti, D | 1 |
| Franceschi, C | 1 |
| Horman, S | 1 |
| Vertommen, D | 1 |
| Heath, R | 1 |
| Neumann, D | 1 |
| Mouton, V | 1 |
| Woods, A | 1 |
| Schlattner, U | 1 |
| Wallimann, T | 1 |
| Carling, D | 1 |
| Hue, L | 1 |
| Rider, MH | 1 |
| Axelsen, LN | 1 |
| Stahlhut, M | 1 |
| Mohammed, S | 1 |
| Larsen, BD | 1 |
| Nielsen, MS | 1 |
| Holstein-Rathlou, NH | 1 |
| Andersen, S | 1 |
| Jensen, ON | 1 |
| Hennan, JK | 1 |
| Kjølbye, AL | 1 |
| Lampe, PD | 1 |
| Cooper, CD | 1 |
| King, TJ | 1 |
| Burt, JM | 1 |
| Chen, ZP | 1 |
| Mitchelhill, KI | 1 |
| Michell, BJ | 1 |
| Stapleton, D | 1 |
| Rodriguez-Crespo, I | 1 |
| Witters, LA | 1 |
| Power, DA | 1 |
| Ortiz de Montellano, PR | 1 |
| Kemp, BE | 1 |
| MacGowan, GA | 1 |
| Du, C | 1 |
| Cowan, DB | 1 |
| Stamm, C | 1 |
| McGowan, FX | 1 |
| Solaro, RJ | 1 |
| Koretsky, AP | 1 |
| Del Nido, PJ | 1 |
13 other studies available for serine and Heart Disease, Ischemic
| Article | Year |
|---|---|
Cardioprotective Mechanism of Leonurine against Myocardial Ischemia through a Liver-Cardiac Crosstalk Metabolomics Study.
Topics: Amino Acids; Animals; Coronary Artery Disease; Fatty Acids; Glycine; Liver; Metabolomics; Myocardial | 2022 |
Tumor necrosis factor-alpha upregulated PHLPP1 through activating nuclear factor-kappa B during myocardial ischemia/reperfusion.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Gene Expression Regulation; Heart Ventricles; Mal | 2018 |
PPARα Stimulation Modulates Myocardial Ischemia-induced Activation of Renin-Angiotensin System.
Topics: Angiotensin-Converting Enzyme 2; Animals; Bradykinin; Clofibrate; Disease Models, Animal; Enzyme Act | 2015 |
Serum insulin-like growth factor binding protein-1 (IGFBP-1) phosphorylation status in subjects with and without ischaemic heart disease.
Topics: Adult; Cardiovascular Diseases; Enzyme-Linked Immunosorbent Assay; Female; Glucose Tolerance Test; H | 2010 |
Protective effect of ligustrazine against myocardial ischaemia reperfusion in rats: the role of endothelial nitric oxide synthase.
Topics: Animals; Apoptosis; Cardiotonic Agents; Caspase 3; Enzyme Inhibitors; Male; Myocardial Infarction; M | 2012 |
Role of RyR2 phosphorylation at S2814 during heart failure progression.
Topics: Adult; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cardiomegaly; Cardiomyopathy, Di | 2012 |
Chronic hypoxia increases endothelial nitric oxide synthase generation of nitric oxide by increasing heat shock protein 90 association and serine phosphorylation.
Topics: Animals; Animals, Newborn; Benzoquinones; Blotting, Western; Chronic Disease; Enzyme Activation; Enz | 2002 |
The different apoptotic potential of the p53 codon 72 alleles increases with age and modulates in vivo ischaemia-induced cell death.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Alleles; Apoptosis; Arginine; bcl-X Protein; Blotting, | 2004 |
Insulin antagonizes ischemia-induced Thr172 phosphorylation of AMP-activated protein kinase alpha-subunits in heart via hierarchical phosphorylation of Ser485/491.
Topics: Adenosine Monophosphate; AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animal | 2006 |
Identification of ischemia-regulated phosphorylation sites in connexin43: A possible target for the antiarrhythmic peptide analogue rotigaptide (ZP123).
Topics: Amino Acid Sequence; Animals; Connexin 43; Heart Arrest; Male; Molecular Sequence Data; Myocardial I | 2006 |
Analysis of Connexin43 phosphorylated at S325, S328 and S330 in normoxic and ischemic heart.
Topics: Animals; Cell Communication; Cells, Cultured; Connexin 43; Fibroblasts; Gap Junctions; Heart Ventric | 2006 |
AMP-activated protein kinase phosphorylation of endothelial NO synthase.
Topics: Amino Acid Sequence; AMP-Activated Protein Kinases; Animals; Aorta; Calmodulin; Cattle; Endothelium, | 1999 |
Ischemic dysfunction in transgenic mice expressing troponin I lacking protein kinase C phosphorylation sites.
Topics: Alanine; Animals; Binding Sites; Calcium; Feedback; Female; Homeostasis; In Vitro Techniques; Mice; | 2001 |