serine has been researched along with Glucose Intolerance in 15 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Glucose Intolerance: A pathological state in which BLOOD GLUCOSE level is less than approximately 140 mg/100 ml of PLASMA at fasting, and above approximately 200 mg/100 ml plasma at 30-, 60-, or 90-minute during a GLUCOSE TOLERANCE TEST. This condition is seen frequently in DIABETES MELLITUS, but also occurs with other diseases and MALNUTRITION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The rapidly increasing prevalence of gestational diabetes mellitus (GDM) globally places a growing population at risk for developing type 2 diabetes mellitus (T2DM), particularly those with persistent impaired glucose tolerance (IGT) postpartum." | 1.37 | Chronically increased S6K1 is associated with impaired IRS1 signaling in skeletal muscle of GDM women with impaired glucose tolerance postpartum. ( Barbour, LA; Friedman, JE; Hernandez, TL; McCurdy, CE, 2011) |
| " We conclude that SNPs in PPARD modify the conversion from IGT to type 2 diabetes, particularly in combination with the SNPs of PGC-1A and PPARG2." | 1.33 | Single nucleotide polymorphisms of PPARD in combination with the Gly482Ser substitution of PGC-1A and the Pro12Ala substitution of PPARG2 predict the conversion from impaired glucose tolerance to type 2 diabetes: the STOP-NIDDM trial. ( Andrulionyte, L; Chiasson, JL; Laakso, M; Peltola, P, 2006) |
| "None of the NIDDM or impaired glucose tolerant patients had this polymorphism." | 1.29 | Lack of association between the Gly40Ser polymorphism in the glucagon receptor gene and NIDDM in Finland. ( Groop, L; Huang, X; Lehto, M; Orho, M, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 8 (53.33) | 24.3611 |
| 2020's | 2 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, H | 1 |
| Dong, M | 1 |
| Yuan, S | 1 |
| Jin, W | 1 |
| Lockridge, A | 1 |
| Gustafson, E | 1 |
| Wong, A | 1 |
| Miller, RF | 1 |
| Alejandro, EU | 1 |
| Suwandhi, L | 1 |
| Hausmann, S | 1 |
| Braun, A | 1 |
| Gruber, T | 1 |
| Heinzmann, SS | 1 |
| Gálvez, EJC | 1 |
| Buck, A | 1 |
| Legutko, B | 1 |
| Israel, A | 1 |
| Feuchtinger, A | 1 |
| Haythorne, E | 1 |
| Staiger, H | 1 |
| Heni, M | 1 |
| Häring, HU | 1 |
| Schmitt-Kopplin, P | 1 |
| Walch, A | 1 |
| Cáceres, CG | 1 |
| Tschöp, MH | 1 |
| Rutter, GA | 1 |
| Strowig, T | 1 |
| Elsner, M | 1 |
| Ussar, S | 1 |
| Okabe, K | 1 |
| Usui, I | 1 |
| Yaku, K | 1 |
| Hirabayashi, Y | 1 |
| Tobe, K | 1 |
| Nakagawa, T | 1 |
| Thewissen, MM | 1 |
| van de Gaar, J | 1 |
| den Boer, AT | 1 |
| Munsters, MJ | 1 |
| Blaak, EE | 1 |
| Duijvestijn, A | 1 |
| Copps, KD | 1 |
| Hançer, NJ | 1 |
| Qiu, W | 1 |
| White, MF | 1 |
| Wang, H | 1 |
| Liu, L | 1 |
| Lin, JZ | 1 |
| Aprahamian, TR | 1 |
| Farmer, SR | 1 |
| Barbour, LA | 1 |
| McCurdy, CE | 1 |
| Hernandez, TL | 1 |
| Friedman, JE | 1 |
| Kiilerich, K | 1 |
| Ringholm, S | 1 |
| Biensø, RS | 1 |
| Fisher, JP | 1 |
| Iversen, N | 1 |
| van Hall, G | 1 |
| Wojtaszewski, JF | 1 |
| Saltin, B | 1 |
| Lundby, C | 1 |
| Calbet, JA | 1 |
| Pilegaard, H | 1 |
| Frogne, T | 1 |
| Sylvestersen, KB | 1 |
| Kubicek, S | 1 |
| Nielsen, ML | 1 |
| Hecksher-Sørensen, J | 1 |
| Barbato, A | 1 |
| Russo, P | 1 |
| Venezia, A | 1 |
| Strazzullo, V | 1 |
| Siani, A | 1 |
| Cappuccio, FP | 1 |
| Fanelli, M | 1 |
| Filippi, E | 1 |
| Sentinelli, F | 1 |
| Romeo, S | 1 |
| Fallarino, M | 1 |
| Buzzetti, R | 1 |
| Leonetti, F | 1 |
| Baroni, MG | 1 |
| Andrulionyte, L | 1 |
| Peltola, P | 1 |
| Chiasson, JL | 1 |
| Laakso, M | 1 |
| Huang, X | 1 |
| Orho, M | 1 |
| Lehto, M | 1 |
| Groop, L | 1 |
| Odawara, M | 1 |
| Tachi, Y | 1 |
| Yamashita, K | 1 |
15 other studies available for serine and Glucose Intolerance
| Article | Year |
|---|---|
Oral glucagon-like peptide 1 analogue ameliorates glucose intolerance in db/db mice.
Topics: Alanine; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Glucagon-Like Pe | 2022 |
Acute D-Serine Co-Agonism of β-Cell NMDA Receptors Potentiates Glucose-Stimulated Insulin Secretion and Excitatory β-Cell Membrane Activity.
Topics: Animals; Blood Glucose; Disease Models, Animal; Female; Glucose; Glucose Intolerance; Homeostasis; I | 2021 |
Chronic d-serine supplementation impairs insulin secretion.
Topics: Animals; Blood Glucose; Body Weight; Diet, High-Fat; Dietary Supplements; Energy Metabolism; Glucose | 2018 |
Deletion of PHGDH in adipocytes improves glucose intolerance in diet-induced obese mice.
Topics: Adipocytes; Adipose Tissue, Brown; Adipose Tissue, White; Animals; Body Weight; Diet; Female; Gene D | 2018 |
Monocytes, but not T cells, respond to insulin with Akt(S473) phosphorylation independent of the donor glucometabolic state.
Topics: Aged; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Diabetes Mellitus, Type 2; Female; Glu | 2014 |
Serine 302 Phosphorylation of Mouse Insulin Receptor Substrate 1 (IRS1) Is Dispensable for Normal Insulin Signaling and Feedback Regulation by Hepatic S6 Kinase.
Topics: Amino Acid Substitution; Animals; CHO Cells; Cricetinae; Cricetulus; Gene Deletion; Glucose Intolera | 2016 |
Browning of White Adipose Tissue with Roscovitine Induces a Distinct Population of UCP1
Topics: Adipocytes; Adipose Tissue, Brown; Adipose Tissue, White; Animals; Diet; Energy Metabolism; Flow Cyt | 2016 |
Chronically increased S6K1 is associated with impaired IRS1 signaling in skeletal muscle of GDM women with impaired glucose tolerance postpartum.
Topics: Adult; Biomarkers; Blood Glucose; Blotting, Western; Diabetes, Gestational; Female; Glucose Intolera | 2011 |
Exercise-induced pyruvate dehydrogenase activation is not affected by 7 days of bed rest.
Topics: Adult; Bed Rest; Biopsy; Blood Glucose; Enzyme Activation; Exercise; Exercise Test; Gene Expression | 2011 |
Pdx1 is post-translationally modified in vivo and serine 61 is the principal site of phosphorylation.
Topics: Animals; Blood Glucose; Chickens; Gene Expression Regulation, Developmental; Glucose Intolerance; HE | 2012 |
Analysis of Gly40Ser polymorphism of the glucagon receptor (GCGR) gene in different ethnic groups.
Topics: Adult; Asian People; Black People; Blood Glucose; Cardiovascular Diseases; Diabetes Mellitus; Female | 2003 |
The Gly482Ser missense mutation of the peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1 alpha) gene associates with reduced insulin sensitivity in normal and glucose-intolerant obese subjects.
Topics: Adult; Amino Acid Substitution; Female; Genetic Predisposition to Disease; Glucose Intolerance; Glyc | 2005 |
Single nucleotide polymorphisms of PPARD in combination with the Gly482Ser substitution of PGC-1A and the Pro12Ala substitution of PPARG2 predict the conversion from impaired glucose tolerance to type 2 diabetes: the STOP-NIDDM trial.
Topics: Amino Acid Substitution; Diabetes Mellitus, Type 2; Disease Progression; Female; Glucose Intolerance | 2006 |
Lack of association between the Gly40Ser polymorphism in the glucagon receptor gene and NIDDM in Finland.
Topics: Alleles; Amino Acid Sequence; Base Sequence; Diabetes Mellitus, Type 2; DNA Primers; Finland; France | 1995 |
Absence of association between the Gly40-->Ser mutation in the human glucagon receptor and Japanese patients with non-insulin-dependent diabetes mellitus or impaired glucose tolerance.
Topics: Adult; Aged; Asian People; Codon; Diabetes Mellitus, Type 2; Exons; Female; Glucose Intolerance; Gly | 1996 |