serine has been researched along with Genome Instability in 14 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The SPOP-mutated subtype of prostate cancer shows high genomic instability, but the underlying mechanisms causing this phenotype are still largely unknown." | 1.62 | Prostate cancer-associated SPOP mutations lead to genomic instability through disruption of the SPOP-HIPK2 axis. ( Cao, X; Cong, L; Fang, S; Gao, K; Gong, Z; Jin, X; Li, J; Li, Q; Lin, T; Lin, Z; Ma, Q; Meng, X; Qi, H; Qing, S; Shen, L; Wang, C; Wang, J; Wang, S; Xi, Y; Yang, J; Ye, M; Zhuang, H, 2021) |
| "Furthermore, they indicate that, genome stability depends mainly on the ability of cells to counteract targeting of branched intermediates by the MUS81/EME1 complex in S-phase, rather than on a correct MUS81 function in mitosis." | 1.48 | Phosphorylation by CK2 regulates MUS81/EME1 in mitosis and after replication stress. ( Franchitto, A; Malacaria, E; Marabitti, V; Mazzei, F; Minoprio, A; Murfuni, I; Palma, A; Pichierri, P; Pugliese, GM; Rinalducci, S; Sanchez, M; Zolla, L, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 9 (64.29) | 24.3611 |
| 2020's | 4 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Brustel, J | 1 |
| Muramoto, T | 1 |
| Fumimoto, K | 1 |
| Ellins, J | 1 |
| Pears, CJ | 1 |
| Lakin, ND | 2 |
| Richards, F | 1 |
| Llorca-Cardenosa, MJ | 1 |
| Langton, J | 1 |
| Buch-Larsen, SC | 1 |
| Shamkhi, NF | 1 |
| Sharma, AB | 1 |
| Nielsen, ML | 1 |
| Wu, L | 1 |
| Crawley, CD | 1 |
| Garofalo, A | 1 |
| Nichols, JW | 1 |
| Campbell, PA | 1 |
| Khramtsova, GF | 1 |
| Olopade, OI | 1 |
| Weichselbaum, RR | 1 |
| Yamini, B | 1 |
| Jin, X | 1 |
| Qing, S | 1 |
| Li, Q | 1 |
| Zhuang, H | 1 |
| Shen, L | 1 |
| Li, J | 1 |
| Qi, H | 1 |
| Lin, T | 1 |
| Lin, Z | 1 |
| Wang, J | 1 |
| Cao, X | 1 |
| Yang, J | 1 |
| Ma, Q | 1 |
| Cong, L | 1 |
| Xi, Y | 1 |
| Fang, S | 1 |
| Meng, X | 1 |
| Gong, Z | 1 |
| Ye, M | 1 |
| Wang, S | 1 |
| Wang, C | 1 |
| Gao, K | 1 |
| Sivanand, S | 1 |
| Rhoades, S | 1 |
| Jiang, Q | 1 |
| Lee, JV | 1 |
| Benci, J | 1 |
| Zhang, J | 1 |
| Yuan, S | 1 |
| Viney, I | 1 |
| Zhao, S | 1 |
| Carrer, A | 1 |
| Bennett, MJ | 1 |
| Minn, AJ | 1 |
| Weljie, AM | 1 |
| Greenberg, RA | 1 |
| Wellen, KE | 1 |
| Palma, A | 1 |
| Pugliese, GM | 1 |
| Murfuni, I | 1 |
| Marabitti, V | 1 |
| Malacaria, E | 1 |
| Rinalducci, S | 1 |
| Minoprio, A | 1 |
| Sanchez, M | 1 |
| Mazzei, F | 1 |
| Zolla, L | 1 |
| Franchitto, A | 1 |
| Pichierri, P | 1 |
| Seibert, M | 1 |
| Krüger, M | 1 |
| Watson, NA | 1 |
| Sen, O | 1 |
| Daum, JR | 1 |
| Slotman, JA | 1 |
| Braun, T | 1 |
| Houtsmuller, AB | 1 |
| Gorbsky, GJ | 1 |
| Jacob, R | 1 |
| Kracht, M | 1 |
| Higgins, JMG | 1 |
| Schmitz, ML | 1 |
| Blackford, AN | 1 |
| Nieminuszczy, J | 1 |
| Schwab, RA | 1 |
| Galanty, Y | 1 |
| Jackson, SP | 1 |
| Niedzwiedz, W | 1 |
| Ahlskog, JK | 1 |
| Larsen, BD | 1 |
| Achanta, K | 1 |
| Sørensen, CS | 1 |
| Bonfiglio, JJ | 1 |
| Fontana, P | 1 |
| Zhang, Q | 1 |
| Colby, T | 1 |
| Gibbs-Seymour, I | 1 |
| Atanassov, I | 1 |
| Bartlett, E | 1 |
| Zaja, R | 1 |
| Ahel, I | 1 |
| Matic, I | 1 |
| Luo, K | 1 |
| Yuan, J | 1 |
| Chen, J | 1 |
| Lou, Z | 1 |
| Harfouche, G | 1 |
| Vaigot, P | 1 |
| Rachidi, W | 1 |
| Rigaud, O | 1 |
| Moratille, S | 1 |
| Marie, M | 1 |
| Lemaitre, G | 1 |
| Fortunel, NO | 1 |
| Martin, MT | 1 |
| Yang, C | 1 |
| Tang, X | 1 |
| Guo, X | 1 |
| Niikura, Y | 1 |
| Kitagawa, K | 1 |
| Cui, K | 1 |
| Wong, ST | 1 |
| Fu, L | 1 |
| Xu, B | 1 |
| Shin, MH | 1 |
| Yuan, M | 1 |
| Zhang, H | 1 |
| Margolick, JB | 1 |
| Kai, M | 1 |
14 other studies available for serine and Genome Instability
| Article | Year |
|---|---|
Linking DNA repair and cell cycle progression through serine ADP-ribosylation of histones.
Topics: ADP-Ribosylation; Cell Cycle; Dictyostelium; DNA Breaks, Double-Stranded; DNA Damage; DNA End-Joinin | 2022 |
Regulation of Rad52-dependent replication fork recovery through serine ADP-ribosylation of PolD3.
Topics: ADP-Ribosylation; DNA Damage; DNA Repair; DNA Replication; Genomic Instability; Humans; Poly (ADP-Ri | 2023 |
p50 mono-ubiquitination and interaction with BARD1 regulates cell cycle progression and maintains genome stability.
Topics: Animals; Binding Sites; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Female; Fibroblasts; Genomic | 2020 |
Prostate cancer-associated SPOP mutations lead to genomic instability through disruption of the SPOP-HIPK2 axis.
Topics: Ataxia Telangiectasia Mutated Proteins; Carrier Proteins; Cell Line, Tumor; Chromobox Protein Homolo | 2021 |
Nuclear Acetyl-CoA Production by ACLY Promotes Homologous Recombination.
Topics: A549 Cells; Acetyl Coenzyme A; Acetylation; Animals; ATP Citrate (pro-S)-Lyase; BRCA1 Protein; Cell | 2017 |
Phosphorylation by CK2 regulates MUS81/EME1 in mitosis and after replication stress.
Topics: Casein Kinase II; DNA Replication; DNA-Binding Proteins; Endodeoxyribonucleases; Endonucleases; Geno | 2018 |
CDK1-mediated phosphorylation at H2B serine 6 is required for mitotic chromosome segregation.
Topics: CDC2 Protein Kinase; Cell Nucleus; Chromosome Segregation; Chromosomes, Human; DNA-Binding Proteins; | 2019 |
TopBP1 interacts with BLM to maintain genome stability but is dispensable for preventing BLM degradation.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Carrier Proteins; Cell Cycle Proteins; DN | 2015 |
ATM/ATR-mediated phosphorylation of PALB2 promotes RAD51 function.
Topics: Actins; Ataxia Telangiectasia Mutated Proteins; Cell Line; DNA Damage; Fanconi Anemia Complementatio | 2016 |
Serine ADP-Ribosylation Depends on HPF1.
Topics: Adenosine Diphosphate Ribose; Carrier Proteins; Cell Line, Tumor; Genomic Instability; Histones; Hum | 2017 |
Topoisomerase IIalpha controls the decatenation checkpoint.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Antigens, Neoplasm; Binding Sites; Cell C | 2009 |
Fibroblast growth factor type 2 signaling is critical for DNA repair in human keratinocyte stem cells.
Topics: Antibodies, Monoclonal; Butadienes; Cell Cycle; Cells, Cultured; Chromatin Assembly and Disassembly; | 2010 |
Aurora-B mediated ATM serine 1403 phosphorylation is required for mitotic ATM activation and the spindle checkpoint.
Topics: Ataxia Telangiectasia Mutated Proteins; Aurora Kinase B; Aurora Kinases; Cell Cycle Proteins; DNA-Bi | 2011 |
ATM-dependent phosphorylation of the checkpoint clamp regulates repair pathways and maintains genomic stability.
Topics: Acid Anhydride Hydrolases; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Checkpoints; Cell Cycl | 2012 |