serine has been researched along with Gangliosidosis, GM1 in 2 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Gangliosidosis, GM1: An autosomal recessive neurodegenerative disorder caused by the absence or deficiency of BETA-GALACTOSIDASE. It is characterized by intralysosomal accumulation of G(M1) GANGLIOSIDE and oligosaccharides, primarily in neurons of the central nervous system. The infantile form is characterized by MUSCLE HYPOTONIA, poor psychomotor development, HIRSUTISM, hepatosplenomegaly, and facial abnormalities. The juvenile form features HYPERACUSIS; SEIZURES; and psychomotor retardation. The adult form features progressive DEMENTIA; ATAXIA; and MUSCLE SPASTICITY. (From Menkes, Textbook of Child Neurology, 5th ed, pp96-7)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wheeler, D | 1 |
| Knapp, E | 1 |
| Bandaru, VV | 1 |
| Wang, Y | 1 |
| Knorr, D | 1 |
| Poirier, C | 1 |
| Mattson, MP | 1 |
| Geiger, JD | 1 |
| Haughey, NJ | 1 |
| Zhang, S | 1 |
| Bagshaw, R | 1 |
| Hilson, W | 1 |
| Oho, Y | 1 |
| Hinek, A | 1 |
| Clarke, JT | 1 |
| Callahan, JW | 1 |
2 other studies available for serine and Gangliosidosis, GM1
| Article | Year |
|---|---|
Tumor necrosis factor-alpha-induced neutral sphingomyelinase-2 modulates synaptic plasticity by controlling the membrane insertion of NMDA receptors.
Topics: Aniline Compounds; Animals; Benzylidene Compounds; Calcium; Cells, Cultured; Ceramides; Embryo, Mamm | 2009 |
Characterization of beta-galactosidase mutations Asp332-->Asn and Arg148-->Ser, and a polymorphism, Ser532-->Gly, in a case of GM1 gangliosidosis.
Topics: Amino Acid Substitution; Animals; Arginine; Asparagine; Aspartic Acid; Base Sequence; beta-Galactosi | 2000 |