serine has been researched along with Frontotemporal Lobar Degeneration in 2 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Frontotemporal Lobar Degeneration: Heterogeneous group of neurodegenerative disorders characterized by frontal and temporal lobe atrophy associated with neuronal loss, gliosis, and dementia. Patients exhibit progressive changes in social, behavioral, and/or language function. Multiple subtypes or forms are recognized based on presence or absence of TAU PROTEIN inclusions. FTLD includes three clinical syndromes: FRONTOTEMPORAL DEMENTIA, semantic dementia, and PRIMARY PROGRESSIVE NONFLUENT APHASIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Frontotemporal lobar degeneration (FTLD) is a progressive neurodegenerative disease characterized by behavioral abnormalities, personality changes, language dysfunction, and can co-occur with the development of motor neuron disease." | 1.36 | Phosphoproteomic analysis reveals site-specific changes in GFAP and NDRG2 phosphorylation in frontotemporal lobar degeneration. ( Duong, DM; Gearing, M; Herskowitz, JH; Lah, JJ; Levey, AI; Peng, J; Rees, HD; Seyfried, NT; Xia, Q, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Herskowitz, JH | 1 |
| Seyfried, NT | 1 |
| Duong, DM | 1 |
| Xia, Q | 1 |
| Rees, HD | 1 |
| Gearing, M | 1 |
| Peng, J | 1 |
| Lah, JJ | 1 |
| Levey, AI | 1 |
| Cruchaga, C | 1 |
| Graff, C | 1 |
| Chiang, HH | 1 |
| Wang, J | 1 |
| Hinrichs, AL | 1 |
| Spiegel, N | 1 |
| Bertelsen, S | 1 |
| Mayo, K | 1 |
| Norton, JB | 1 |
| Morris, JC | 1 |
| Goate, A | 1 |
2 other studies available for serine and Frontotemporal Lobar Degeneration
| Article | Year |
|---|---|
Phosphoproteomic analysis reveals site-specific changes in GFAP and NDRG2 phosphorylation in frontotemporal lobar degeneration.
Topics: Aged; Amino Acid Sequence; Binding Sites; Brain; Chromatography, Affinity; Chromatography, Liquid; D | 2010 |
Association of TMEM106B gene polymorphism with age at onset in granulin mutation carriers and plasma granulin protein levels.
Topics: Age of Onset; Aged; Alzheimer Disease; Amino Acid Substitution; Female; Frontotemporal Lobar Degener | 2011 |