serine has been researched along with Fanconi Anemia in 3 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Fanconi Anemia: Congenital disorder affecting all bone marrow elements, resulting in ANEMIA; LEUKOPENIA; and THROMBOPENIA, and associated with cardiac, renal, and limb malformations as well as dermal pigmentary changes. Spontaneous CHROMOSOME BREAKAGE is a feature of this disease along with predisposition to LEUKEMIA. There are at least 7 complementation groups in Fanconi anemia: FANCA, FANCB, FANCC, FANCD1, FANCD2, FANCE, FANCF, FANCG, and FANCL. (from Online Mendelian Inheritance in Man, http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227650, August 20, 2004)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fanconi anemia is a cancer-prone inherited bone marrow failure and cancer susceptibility syndrome with at least 13 complementation groups (FANCA, FANCB, FANCC, FANCD1, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ, FANCL, FANCM, and FANCN)." | 5.35 | Fanconi anemia complementation group FANCD2 protein serine 331 phosphorylation is important for fanconi anemia pathway function and BRCA2 interaction. ( Chen, X; Jones, NJ; Krause, DS; Kupfer, GM; Wilson, JB; Xiao, Y; Zhi, G, 2009) |
| "Fanconi anemia is a cancer-prone inherited bone marrow failure and cancer susceptibility syndrome with at least 13 complementation groups (FANCA, FANCB, FANCC, FANCD1, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ, FANCL, FANCM, and FANCN)." | 1.35 | Fanconi anemia complementation group FANCD2 protein serine 331 phosphorylation is important for fanconi anemia pathway function and BRCA2 interaction. ( Chen, X; Jones, NJ; Krause, DS; Kupfer, GM; Wilson, JB; Xiao, Y; Zhi, G, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Singh, TR | 1 |
| Ali, AM | 1 |
| Paramasivam, M | 1 |
| Pradhan, A | 1 |
| Wahengbam, K | 1 |
| Seidman, MM | 1 |
| Meetei, AR | 1 |
| Collins, NB | 1 |
| Wilson, JB | 2 |
| Bush, T | 1 |
| Thomashevski, A | 1 |
| Roberts, KJ | 1 |
| Jones, NJ | 2 |
| Kupfer, GM | 2 |
| Zhi, G | 1 |
| Chen, X | 1 |
| Krause, DS | 1 |
| Xiao, Y | 1 |
3 other studies available for serine and Fanconi Anemia
| Article | Year |
|---|---|
ATR-dependent phosphorylation of FANCM at serine 1045 is essential for FANCM functions.
Topics: Ataxia Telangiectasia Mutated Proteins; Cell Division; Cell Line; Cell Line, Tumor; Checkpoint Kinas | 2013 |
ATR-dependent phosphorylation of FANCA on serine 1449 after DNA damage is important for FA pathway function.
Topics: Alkylating Agents; Ataxia Telangiectasia Mutated Proteins; Blotting, Western; Cell Cycle Proteins; D | 2009 |
Fanconi anemia complementation group FANCD2 protein serine 331 phosphorylation is important for fanconi anemia pathway function and BRCA2 interaction.
Topics: Amino Acid Sequence; Animals; BRCA2 Protein; Cell Line; Checkpoint Kinase 1; DNA Damage; Fanconi Ane | 2009 |