serine has been researched along with Epilepsies, Partial in 5 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Epilepsies, Partial: Conditions characterized by recurrent paroxysmal neuronal discharges which arise from a focal region of the brain. Partial seizures are divided into simple and complex, depending on whether consciousness is unaltered (simple partial seizure) or disturbed (complex partial seizure). Both types may feature a wide variety of motor, sensory, and autonomic symptoms. Partial seizures may be classified by associated clinical features or anatomic location of the seizure focus. A secondary generalized seizure refers to a partial seizure that spreads to involve the brain diffusely. (From Adams et al., Principles of Neurology, 6th ed, pp317)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amino acid analysis of plasma and urine obtained from 12 patients with epilepsy indicated that the plasma concentrations of taurine and glutamic acid were much higher than might have been expected." | 7.65 | Biochemical observations following administration of taurine to patients with epilepsy. ( Anderman, F; Sacks, C; Sherwin, AL; Van Gelder, NM, 1975) |
| "Amino acid analysis of plasma and urine obtained from 12 patients with epilepsy indicated that the plasma concentrations of taurine and glutamic acid were much higher than might have been expected." | 3.65 | Biochemical observations following administration of taurine to patients with epilepsy. ( Anderman, F; Sacks, C; Sherwin, AL; Van Gelder, NM, 1975) |
| "The patient developed a series of partial seizures during an 8 min period." | 1.28 | Seizure related elevations of extracellular amino acids in human focal epilepsy. ( Carlson, H; Hillered, L; Ronne-Engström, E; Ungerstedt, U, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Coppola, G | 1 |
| Veggiotti, P | 1 |
| Del Giudice, EM | 1 |
| Bellini, G | 1 |
| Longaretti, F | 1 |
| Taglialatela, M | 1 |
| Pascotto, A | 1 |
| Weiland, S | 1 |
| Witzemann, V | 1 |
| Villarroel, A | 1 |
| Propping, P | 1 |
| Steinlein, O | 1 |
| Van Gelder, NM | 2 |
| Sherwin, AL | 1 |
| Sacks, C | 1 |
| Anderman, F | 1 |
| Carlson, H | 1 |
| Ronne-Engström, E | 1 |
| Ungerstedt, U | 1 |
| Hillered, L | 1 |
| Courtois, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Taurine as an Anti-Manic Agent: A Double-Blind, Placebo-Controlled Study in Adolescents With Bipolar Disorder[NCT00391001] | Phase 1 | 4 participants (Actual) | Interventional | 2006-02-28 | Terminated | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 other studies available for serine and Epilepsies, Partial
| Article | Year |
|---|---|
Mutational scanning of potassium, sodium and chloride ion channels in malignant migrating partial seizures in infancy.
Topics: Aminopeptidases; Child; Child, Preschool; Chloride Channels; Dipeptidyl-Peptidases and Tripeptidyl-P | 2006 |
An amino acid exchange in the second transmembrane segment of a neuronal nicotinic receptor causes partial epilepsy by altering its desensitization kinetics.
Topics: Acetylcholine; Amino Acid Sequence; Animals; Binding Sites; DNA, Complementary; Electric Conductivit | 1996 |
Biochemical observations following administration of taurine to patients with epilepsy.
Topics: Adolescent; Adult; Alanine; Anticonvulsants; Aspartic Acid; Cerebral Cortex; Child; Child, Preschool | 1975 |
Seizure related elevations of extracellular amino acids in human focal epilepsy.
Topics: Amino Acids; Asparagine; Aspartic Acid; Cerebral Cortex; Dialysis; Electroencephalography; Epilepsie | 1992 |
Close correlation between changing content of specific amino acids in epileptogenic cortex of cats, and severity of epilepsy.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Cats; Cerebral Cortex; Cobalt; Electro | 1972 |