serine has been researched along with Ependymoma in 2 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Ependymoma: Glioma derived from EPENDYMOGLIAL CELLS that tend to present as malignant intracranial tumors in children and as benign intraspinal neoplasms in adults. It may arise from any level of the ventricular system or central canal of the spinal cord. Intracranial ependymomas most frequently originate in the FOURTH VENTRICLE and histologically are densely cellular tumors which may contain ependymal tubules and perivascular pseudorosettes. Spinal ependymomas are usually benign papillary or myxopapillary tumors. (From DeVita et al., Principles and Practice of Oncology, 5th ed, p2018; Escourolle et al., Manual of Basic Neuropathology, 2nd ed, pp28-9)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Recurrent ependymomas are considered rarely responsive to chemotherapy and often have a dismal prognosis after tumor progression." | 5.37 | mTORC1 activation in childhood ependymoma and response to sirolimus. ( Bowers, DC; Brugarolas, J; Gargan, L; Kucejova, B; Margraf, L, 2011) |
| "Recurrent ependymomas are considered rarely responsive to chemotherapy and often have a dismal prognosis after tumor progression." | 1.37 | mTORC1 activation in childhood ependymoma and response to sirolimus. ( Bowers, DC; Brugarolas, J; Gargan, L; Kucejova, B; Margraf, L, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dutta, R | 1 |
| Sharma, MC | 1 |
| Suri, V | 1 |
| Sarkar, C | 1 |
| Garg, A | 1 |
| Suri, A | 1 |
| Kale, SS | 1 |
| Bowers, DC | 1 |
| Kucejova, B | 1 |
| Margraf, L | 1 |
| Gargan, L | 1 |
| Brugarolas, J | 1 |
2 other studies available for serine and Ependymoma
| Article | Year |
|---|---|
TTF-1: A Well-Favored Addition to the Immunohistochemistry Armamentarium as a Diagnostic Marker of SEGA.
Topics: Astrocytoma; Brain Neoplasms; Child; Ependymoma; Glioblastoma; Humans; Immunohistochemistry; Neurocy | 2022 |
mTORC1 activation in childhood ependymoma and response to sirolimus.
Topics: Brain Neoplasms; Child, Preschool; Ependymoma; Humans; Immunosuppressive Agents; Magnetic Resonance | 2011 |