serine has been researched along with Diathesis in 9 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We showed previously that hypoxia-induced seizures in a neonatal rat model induce rapid phosphorylation of serine-831 (S831) and Serine 845 (S845) sites of the AMPA receptor GluR1 subunit and later neuronal hyperexcitability and epilepsy, suggesting that seizure-induced posttranslational modifications may represent a novel therapeutic target." | 7.78 | Glutamate receptor 1 phosphorylation at serine 831 and 845 modulates seizure susceptibility and hippocampal hyperexcitability after early life seizures. ( Fitzgerald, EF; Huganir, RL; Hunganir, RL; Jensen, FE; Klein, PM; Rakhade, SN; Sun, H; Zhou, C, 2012) |
| " We showed previously that hypoxia-induced seizures in a neonatal rat model induce rapid phosphorylation of serine-831 (S831) and Serine 845 (S845) sites of the AMPA receptor GluR1 subunit and later neuronal hyperexcitability and epilepsy, suggesting that seizure-induced posttranslational modifications may represent a novel therapeutic target." | 3.78 | Glutamate receptor 1 phosphorylation at serine 831 and 845 modulates seizure susceptibility and hippocampal hyperexcitability after early life seizures. ( Fitzgerald, EF; Huganir, RL; Hunganir, RL; Jensen, FE; Klein, PM; Rakhade, SN; Sun, H; Zhou, C, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Nyamsuren, G | 1 |
| Rapp, G | 1 |
| Dihazi, H | 1 |
| Zeisberg, EM | 1 |
| Tampe, D | 1 |
| Tampe, B | 1 |
| Zeisberg, M | 1 |
| Pavlov, VA | 1 |
| Kotomtsev, VV | 1 |
| Doronin, AI | 1 |
| Sabadash, EV | 1 |
| Chu, EP | 1 |
| Elso, CM | 1 |
| Pollock, AH | 1 |
| Alsayb, MA | 1 |
| Mackin, L | 1 |
| Thomas, HE | 1 |
| Kay, TW | 1 |
| Silveira, PA | 1 |
| Mansell, AS | 1 |
| Gaus, K | 1 |
| Brodnicki, TC | 1 |
| Labrie, V | 1 |
| Fukumura, R | 1 |
| Rastogi, A | 1 |
| Fick, LJ | 1 |
| Wang, W | 1 |
| Boutros, PC | 1 |
| Kennedy, JL | 1 |
| Semeralul, MO | 1 |
| Lee, FH | 1 |
| Baker, GB | 1 |
| Belsham, DD | 1 |
| Barger, SW | 1 |
| Gondo, Y | 1 |
| Wong, AH | 1 |
| Roder, JC | 1 |
| Rakhade, SN | 1 |
| Fitzgerald, EF | 1 |
| Klein, PM | 1 |
| Zhou, C | 1 |
| Sun, H | 1 |
| Huganir, RL | 1 |
| Hunganir, RL | 1 |
| Jensen, FE | 1 |
| Hu, X | 1 |
| Giotakis, O | 1 |
| Li, T | 1 |
| Karwautz, A | 1 |
| Treasure, J | 1 |
| Collier, DA | 1 |
| Coates, PJ | 1 |
| Lorimore, SA | 1 |
| Lindsay, KJ | 1 |
| Wright, EG | 1 |
| Chen, WF | 1 |
| Chang, H | 1 |
| Huang, LT | 1 |
| Lai, MC | 1 |
| Yang, CH | 1 |
| Wan, TH | 1 |
| Yang, SN | 1 |
| Elbein, SC | 1 |
| Hoffman, MD | 1 |
9 other studies available for serine and Diathesis
| Article | Year |
|---|---|
PP2A phosphatase inhibition is anti-fibrotic through Ser77 phosphorylation-mediated ARNT/ARNT homodimer formation.
Topics: Amino Acid Sequence; Animals; Aryl Hydrocarbon Receptor Nuclear Translocator; Biomarkers; Disease Mo | 2021 |
Antioxidant and Antimutagenic Metabolites in Animals with Opposite Sensitivity to Tuberculosis Mycobacteria and Mutagenic Xenobiotics.
Topics: Animals; Disease Susceptibility; Ethanolamine; Ethanolamines; Glutathione; Guinea Pigs; Liver; Methi | 2016 |
Disruption of Serinc1, which facilitates serine-derived lipid synthesis, fails to alter macrophage function, lymphocyte proliferation or autoimmune disease susceptibility.
Topics: Animals; Autoimmune Diseases; Cell Separation; Diabetes Mellitus, Experimental; Disease Models, Anim | 2017 |
Serine racemase is associated with schizophrenia susceptibility in humans and in a mouse model.
Topics: Animals; Case-Control Studies; Disease Models, Animal; Disease Susceptibility; Female; Humans; Male; | 2009 |
Glutamate receptor 1 phosphorylation at serine 831 and 845 modulates seizure susceptibility and hippocampal hyperexcitability after early life seizures.
Topics: Animals; Animals, Newborn; Cerebral Cortex; Disease Models, Animal; Disease Susceptibility; Disks La | 2012 |
Association of the 5-HT2c gene with susceptibility and minimum body mass index in anorexia nervosa.
Topics: Alleles; Anorexia Nervosa; Body Mass Index; Case-Control Studies; Cystine; Disease Susceptibility; F | 2003 |
Tissue-specific p53 responses to ionizing radiation and their genetic modification: the key to tissue-specific tumour susceptibility?
Topics: Animals; Apoptosis; Disease Susceptibility; Epithelium; Genetic Predisposition to Disease; Hematopoi | 2003 |
Alterations in long-term seizure susceptibility and the complex of PSD-95 with NMDA receptor from animals previously exposed to perinatal hypoxia.
Topics: Animals; Animals, Newborn; Brain; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Disease M | 2006 |
Role of mitochondrial DNA tRNA leucine and glucagon receptor missense mutations in Utah white diabetic patients.
Topics: Alleles; Disease Susceptibility; DNA, Mitochondrial; Europe; Female; Glucose Tolerance Test; Glycine | 1996 |