Page last updated: 2024-11-08

serine and Diabetic Retinopathy

serine has been researched along with Diabetic Retinopathy in 10 studies

Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.

Diabetic Retinopathy: Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.

Research Excerpts

ExcerptRelevanceReference
"The objective of this clinical study is to examine the association between D-serine and diabetic retinopathy (DR)."7.80Increased D-serine in the aqueous and vitreous humour in patients with proliferative diabetic retinopathy. ( Du, J; He, T; Jiang, H; Qu, J; Song, Z; Wu, S, 2014)
"The objective of this clinical study is to examine the association between D-serine and diabetic retinopathy (DR)."3.80Increased D-serine in the aqueous and vitreous humour in patients with proliferative diabetic retinopathy. ( Du, J; He, T; Jiang, H; Qu, J; Song, Z; Wu, S, 2014)
"703 patients with type 1 diabetes mellitus from one endocrine department were included in the study."1.51Protective Effect of the ( Catrina, SB; Chatzidionysiou, K; Ekberg, NR; Eliasson, S; Falhammar, H; Gu, HF; Li, YW; Zheng, X, 2019)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (20.00)29.6817
2010's5 (50.00)24.3611
2020's3 (30.00)2.80

Authors

AuthorsStudies
Malhi, NK1
Allen, CL1
Stewart, E1
Horton, KL1
Riu, F1
Batson, J1
Amoaku, W1
Morris, JC1
Arkill, KP1
Bates, DO1
Alka, K1
Mohammad, G1
Kowluru, RA1
Eade, KT1
Ansell, BRE1
Giles, S1
Fallon, R1
Harkins-Perry, S1
Nagasaki, T1
Tzaridis, S1
Wallace, M1
Mills, EA1
Farashi, S1
Johnson, A1
Sauer, L1
Hart, B1
Diaz-Rubio, ME1
Bahlo, M1
Metallo, C1
Allikmets, R1
Gantner, ML1
Bernstein, PS1
Friedlander, M1
Ekberg, NR1
Eliasson, S1
Li, YW1
Zheng, X1
Chatzidionysiou, K1
Falhammar, H1
Gu, HF1
Catrina, SB1
Jiang, H2
Du, J1
He, T1
Qu, J2
Song, Z1
Wu, S2
Li, X1
Liu, X1
Guo, H1
Zhao, Z1
Li, YS1
Chen, G1
Zhang, HM1
Chen, LL1
Wang, L1
Liao, YF1
Wu, ZH1
Ye, F1
Xu, S1
Yi, LL1
Panjala, SR1
Jiang, Y1
Kern, TS1
Thomas, SA1
Steinle, JJ1
Fang, J1
Wu, B1
Yin, G1
Sun, L2
Barger, SW1
Al-Kateb, H1
Boright, AP1
Mirea, L1
Xie, X1
Sutradhar, R1
Mowjoodi, A1
Bharaj, B1
Liu, M1
Bucksa, JM1
Arends, VL1
Steffes, MW1
Cleary, PA1
Sun, W1
Lachin, JM1
Thorner, PS1
Ho, M1
McKnight, AJ1
Maxwell, AP1
Savage, DA1
Kidd, KK1
Kidd, JR1
Speed, WC1
Orchard, TJ1
Miller, RG1
Bull, SB1
Paterson, AD1

Trials

1 trial available for serine and Diabetic Retinopathy

ArticleYear
Multiple superoxide dismutase 1/splicing factor serine alanine 15 variants are associated with the development and progression of diabetic nephropathy: the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications G
    Diabetes, 2008, Volume: 57, Issue:1

    Topics: Alanine; Albuminuria; Amino Acid Substitution; Diabetic Nephropathies; Diabetic Retinopathy; Disease

2008

Other Studies

9 other studies available for serine and Diabetic Retinopathy

ArticleYear
Serine-arginine-rich protein kinase-1 inhibition for the treatment of diabetic retinopathy.
    American journal of physiology. Heart and circulatory physiology, 2022, 06-01, Volume: 322, Issue:6

    Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Humans; Hyperglycemia; Mac

2022
Regulation of serine palmitoyl-transferase and Rac1-Nox2 signaling in diabetic retinopathy.
    Scientific reports, 2022, 10-06, Volume: 12, Issue:1

    Topics: Animals; Ceramides; Cytosine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic R

2022
iPSC-derived retinal pigmented epithelial cells from patients with macular telangiectasia show decreased mitochondrial function.
    The Journal of clinical investigation, 2023, 05-01, Volume: 133, Issue:9

    Topics: Diabetic Retinopathy; Epithelial Cells; Humans; Induced Pluripotent Stem Cells; Mitochondria; Retina

2023
Protective Effect of the
    Journal of diabetes research, 2019, Volume: 2019

    Topics: Adult; Aged; Aged, 80 and over; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Di

2019
Increased D-serine in the aqueous and vitreous humour in patients with proliferative diabetic retinopathy.
    Clinical & experimental ophthalmology, 2014, Volume: 42, Issue:9

    Topics: Aged; Aqueous Humor; Case-Control Studies; Chromatography, High Pressure Liquid; Diabetes Mellitus,

2014
The significance of the increased expression of phosphorylated MeCP2 in the membranes from patients with proliferative diabetic retinopathy.
    Scientific reports, 2016, 09-12, Volume: 6

    Topics: Adult; Aged; Cell Line; Cobalt; Diabetic Retinopathy; Epiretinal Membrane; Eye Proteins; Female; Hum

2016
Association of 1704G/T and G82S polymorphisms in the receptor for advanced glycation end products gene with diabetic retinopathy in Chinese population.
    Journal of endocrinological investigation, 2009, Volume: 32, Issue:3

    Topics: Adult; Aged; Amino Acid Substitution; Case-Control Studies; China; Diabetes Mellitus, Type 2; Diabet

2009
Increased tumor necrosis factor-α, cleaved caspase 3 levels and insulin receptor substrate-1 phosphorylation in the β₁-adrenergic receptor knockout mouse.
    Molecular vision, 2011, Volume: 17

    Topics: Animals; Apoptosis; Blotting, Western; Capillaries; Caspase 3; Cell Extracts; Diabetes Complications

2011
Overexpression of serine racemase in retina and overproduction of D-serine in eyes of streptozotocin-induced diabetic retinopathy.
    Journal of neuroinflammation, 2011, Sep-22, Volume: 8

    Topics: Animals; Aqueous Humor; Blood Glucose; Body Weight; Cell Death; Diabetes Mellitus, Experimental; Dia

2011