serine has been researched along with Diabetic Glomerulosclerosis in 13 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diabetes mellitus is a metabolic disease that is characterized by chronic hyperglycemia due to a variety of etiological factors." | 3.01 | RIPK1 and RIPK3 inhibitors: potential weapons against inflammation to treat diabetic complications. ( Chen, P; Chu, Y; Dai, Y; Ke, D; Li, L; Liu, J; Sun, X; Zhang, Z, 2023) |
| "The diagnosis of diabetic nephropathy (DN), the major cause of ESKD, requires kidney biopsy." | 1.62 | Identification of Diabetic Nephropathy in Patients Undergoing Kidney Biopsy through Blood and Urinary Profiles of d-Serine. ( Hayashi, T; Hesaka, A; Horio, M; Ikeda, T; Imamura, R; Isaka, Y; Iwata, Y; Kawamura, M; Kimura, T; Mita, M; Nakane, M; Okushima, H; Takahara, S; Tanaka, Y, 2021) |
| "703 patients with type 1 diabetes mellitus from one endocrine department were included in the study." | 1.51 | Protective Effect of the ( Catrina, SB; Chatzidionysiou, K; Ekberg, NR; Eliasson, S; Falhammar, H; Gu, HF; Li, YW; Zheng, X, 2019) |
| "We conclude that advanced diabetic nephropathy is associated with increased renal H3K9 and H3K23 acetylation, H3K4 dimethylation and H3 phosphorylation at serine 10 that enhance chromatin unfolding and gene expression." | 1.36 | Progressive glomerulosclerosis in type 2 diabetes is associated with renal histone H3K9 and H3K23 acetylation, H3K4 dimethylation and phosphorylation at serine 10. ( Anders, HJ; Eulberg, D; Gaikwad, AB; Klussmann, S; Kulkarni, O; Lichtnekert, J; Sayyed, SG; Tikoo, K, 2010) |
| "In db/db mice at 2 weeks of type 2 diabetes, VEGF expression was increased, which was due not to increase in transcription but to augmented translation of VEGF mRNA." | 1.35 | PKCdelta regulates the stimulation of vascular endothelial factor mRNA translation by angiotensin II through hnRNP K. ( Feliers, D; Lee, MJ; Mariappan, MM; Sataranatarajan, K, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.69) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 3 (23.08) | 24.3611 |
| 2020's | 6 (46.15) | 2.80 |
| Authors | Studies |
|---|---|
| Iwata, Y | 1 |
| Okushima, H | 1 |
| Hesaka, A | 1 |
| Kawamura, M | 1 |
| Imamura, R | 1 |
| Takahara, S | 1 |
| Horio, M | 1 |
| Tanaka, Y | 1 |
| Ikeda, T | 1 |
| Nakane, M | 1 |
| Mita, M | 1 |
| Hayashi, T | 1 |
| Isaka, Y | 1 |
| Kimura, T | 1 |
| Chen, H | 1 |
| Liu, C | 2 |
| Wang, Q | 1 |
| Xiong, M | 1 |
| Zeng, X | 1 |
| Yang, D | 1 |
| Xie, Y | 1 |
| Su, H | 1 |
| Zhang, Y | 1 |
| Huang, Y | 1 |
| Chen, Y | 1 |
| Yue, J | 1 |
| Wang, S | 1 |
| Huang, K | 1 |
| Zheng, L | 1 |
| Rousseau, M | 2 |
| Denhez, B | 2 |
| Spino, C | 2 |
| Lizotte, F | 2 |
| Guay, A | 2 |
| Côté, AM | 1 |
| Burger, D | 1 |
| Geraldes, P | 2 |
| Chen, JX | 1 |
| Fang, QJ | 1 |
| Wan, YG | 1 |
| Liu, YL | 1 |
| Wang, Y | 1 |
| Wu, W | 1 |
| Tu, Y | 1 |
| Wang, MZ | 1 |
| Wang, DG | 1 |
| Ge, HT | 1 |
| Ke, D | 1 |
| Zhang, Z | 1 |
| Liu, J | 1 |
| Chen, P | 1 |
| Dai, Y | 1 |
| Sun, X | 1 |
| Chu, Y | 1 |
| Li, L | 1 |
| Dancosst, DA | 1 |
| Dumas, MÈ | 1 |
| Ekberg, NR | 1 |
| Eliasson, S | 1 |
| Li, YW | 1 |
| Zheng, X | 1 |
| Chatzidionysiou, K | 1 |
| Falhammar, H | 1 |
| Gu, HF | 1 |
| Catrina, SB | 1 |
| Borsting, E | 1 |
| Patel, SV | 1 |
| Declèves, AE | 1 |
| Lee, SJ | 1 |
| Rahman, QM | 1 |
| Akira, S | 1 |
| Satriano, J | 1 |
| Sharma, K | 1 |
| Vallon, V | 1 |
| Cunard, R | 1 |
| Sayyed, SG | 1 |
| Gaikwad, AB | 1 |
| Lichtnekert, J | 1 |
| Kulkarni, O | 1 |
| Eulberg, D | 1 |
| Klussmann, S | 1 |
| Tikoo, K | 1 |
| Anders, HJ | 1 |
| TEUSCHER, A | 1 |
| LUGINBUEHL, H | 1 |
| Prevost, G | 1 |
| Fajardy, I | 1 |
| Besmond, C | 1 |
| Balkau, B | 1 |
| Tichet, J | 1 |
| Fontaine, P | 1 |
| Danze, PM | 1 |
| Marre, M | 1 |
| Al-Kateb, H | 1 |
| Boright, AP | 1 |
| Mirea, L | 1 |
| Xie, X | 1 |
| Sutradhar, R | 1 |
| Mowjoodi, A | 1 |
| Bharaj, B | 1 |
| Liu, M | 1 |
| Bucksa, JM | 1 |
| Arends, VL | 1 |
| Steffes, MW | 1 |
| Cleary, PA | 1 |
| Sun, W | 1 |
| Lachin, JM | 1 |
| Thorner, PS | 1 |
| Ho, M | 1 |
| McKnight, AJ | 1 |
| Maxwell, AP | 1 |
| Savage, DA | 1 |
| Kidd, KK | 1 |
| Kidd, JR | 1 |
| Speed, WC | 1 |
| Orchard, TJ | 1 |
| Miller, RG | 1 |
| Sun, L | 1 |
| Bull, SB | 1 |
| Paterson, AD | 1 |
| Sataranatarajan, K | 1 |
| Lee, MJ | 1 |
| Mariappan, MM | 1 |
| Feliers, D | 1 |
1 review available for serine and Diabetic Glomerulosclerosis
| Article | Year |
|---|---|
RIPK1 and RIPK3 inhibitors: potential weapons against inflammation to treat diabetic complications.
Topics: Diabetes Complications; Diabetes Mellitus; Diabetic Nephropathies; Humans; Inflammation; Receptor-In | 2023 |
1 trial available for serine and Diabetic Glomerulosclerosis
| Article | Year |
|---|---|
Multiple superoxide dismutase 1/splicing factor serine alanine 15 variants are associated with the development and progression of diabetic nephropathy: the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications G
Topics: Alanine; Albuminuria; Amino Acid Substitution; Diabetic Nephropathies; Diabetic Retinopathy; Disease | 2008 |
11 other studies available for serine and Diabetic Glomerulosclerosis
| Article | Year |
|---|---|
Identification of Diabetic Nephropathy in Patients Undergoing Kidney Biopsy through Blood and Urinary Profiles of d-Serine.
Topics: Biopsy; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Kidney; Serine | 2021 |
Renal UTX-PHGDH-serine axis regulates metabolic disorders in the kidney and liver.
Topics: Diabetic Nephropathies; Histone Demethylases; Humans; Kidney; Liver; Metabolic Diseases; Obesity; Ph | 2022 |
Reduction of DUSP4 contributes to podocytes oxidative stress, insulin resistance and diabetic nephropathy.
Topics: Animals; Apoptosis; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glucose; Insulin; Insul | 2022 |
[Effects and mechanisms of total flavones of Abelmoschus manihot in inhibiting podocyte necroptosis and renal fibrosis in diabetic kidney disease].
Topics: Abelmoschus; Animals; Collagen; Diabetes Mellitus; Diabetic Nephropathies; Fibrosis; Flavones; Human | 2023 |
Saturated fatty acids induce insulin resistance in podocytes through inhibition of IRS1 via activation of both IKKβ and mTORC1.
Topics: Animals; Diabetic Nephropathies; Fatty Acids; I-kappa B Kinase; Insulin; Insulin Receptor Substrate | 2020 |
Protective Effect of the
Topics: Adult; Aged; Aged, 80 and over; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Di | 2019 |
Tribbles homolog 3 attenuates mammalian target of rapamycin complex-2 signaling and inflammation in the diabetic kidney.
Topics: Albuminuria; Animals; Carrier Proteins; Cell Cycle Proteins; Diabetic Nephropathies; Endoplasmic Ret | 2014 |
Progressive glomerulosclerosis in type 2 diabetes is associated with renal histone H3K9 and H3K23 acetylation, H3K4 dimethylation and phosphorylation at serine 10.
Topics: Acetylation; Animals; Base Sequence; Chemokine CCL2; Diabetes Mellitus, Type 2; Diabetic Nephropathi | 2010 |
[ANTIHYPERTENSIVE PROPERTIES OF A MONOAMINE OXIDASE INHIBITOR (DL-SERINE-N2-ISOPROPYLHYDRAZIDE: RO 4-1038). CLINICAL RESULTS AND EFFECT ON RENAL FUNCTION].
Topics: Antihypertensive Agents; Blood Pressure Determination; Chemical and Drug Induced Liver Injury; Chlor | 1964 |
Polymorphisms of the receptor of advanced glycation endproducts (RAGE) and the development of nephropathy in type 1 diabetic patients.
Topics: Amino Acid Substitution; Arginine; Cross-Sectional Studies; Cysteine; Diabetes Mellitus, Type 1; Dia | 2005 |
PKCdelta regulates the stimulation of vascular endothelial factor mRNA translation by angiotensin II through hnRNP K.
Topics: 3' Untranslated Regions; Angiotensin II; Animals; Cell Line; Diabetes Mellitus, Type 2; Diabetic Nep | 2008 |