Page last updated: 2024-11-08

serine and Deficiency, Vitamin B 12

serine has been researched along with Deficiency, Vitamin B 12 in 16 studies

Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199015 (93.75)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
MacMillan, L1
Tingley, G1
Young, SK1
Clow, KA1
Randell, EW1
Brosnan, ME1
Brosnan, JT1
MORUZZI, G1
MARCHETTI, M2
VIVIANI, R1
CHANG, I1
JOHNSON, BC2
Tikerpae, J1
Chanarin, I2
Vidal, AJ1
Stokstad, EL2
Robertson, JS1
Hsia, YE1
Scully, KJ1
Deacon, R1
Lumb, M1
Muir, M1
Perry, J1
van der Westhuyzen, J1
Davis, RE1
Icke, GC1
Metz, J1
Shane, B1
Ellegaard, J1
Esmann, V1
Rubin, HM1
Giorgio, AJ1
Macdonald, RR1
Linarelli, LG1
Waxman, S1
Corcino, J1
Herbert, V1
DeGrazia, JA1
Fish, MB1
Pollycove, M1
Wallerstein, RO1
Hollander, L1
Venkataraman, S1
Walerych, W1
Dryden, LP1
Hartman, AM1
Caldarera, CM1
Barbiroli, B1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Folic Acid Clinical Trial (FACT): Biomarker Subgroup Analysis[NCT03981029]51 participants (Actual)Observational2011-12-19Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for serine and Deficiency, Vitamin B 12

ArticleYear
Cobalamin-folate interrelations: a critical review.
    Blood, 1985, Volume: 66, Issue:3

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Anemia, Megaloblastic; Animals; Central N

1985
Vitamin B12-folate interrelationships.
    Annual review of nutrition, 1985, Volume: 5

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acids; Animals; Bone Marrow; Folic

1985
Aggravation or initiation of megaloblastosis by amino acids in the diet.
    JAMA, 1970, Oct-05, Volume: 214, Issue:1

    Topics: Amino Acids; Anemia, Pernicious; Cell Nucleus; Diet; DNA; Erythrocytes; Folic Acid; Folic Acid Defic

1970

Other Studies

13 other studies available for serine and Deficiency, Vitamin B 12

ArticleYear
Cobalamin Deficiency Results in Increased Production of Formate Secondary to Decreased Mitochondrial Oxidation of One-Carbon Units in Rats.
    The Journal of nutrition, 2018, 03-01, Volume: 148, Issue:3

    Topics: Animals; Carbon; Carbon Dioxide; Cytosol; Folic Acid; Formates; Glycine; Liver; Male; Mitochondria,

2018
OROTIC ACID AND METABOLISM OF ONE CARBON UNIT: CONVERSION OF FOLIC ACID TO CITROVORUM FACTOR AND METHIONINE SYNTHESIS IN CHICK LIVER.
    Archives italiennes de biologie, 1963, Oct-05, Volume: 101

    Topics: Animals; Carbon; Chickens; Folic Acid; Homocysteine; Leuconostoc; Leucovorin; Liver; Metabolism; Met

1963
The effect of vitamin B12 on some aspects of glycine metabolism.
    Archives of biochemistry and biophysics, 1955, Volume: 55, Issue:1

    Topics: Biochemical Phenomena; Choline; Glycine; Serine; Vitamin B 12; Vitamin B 12 Deficiency

1955
Folate-dependent serine synthesis in lymphocytes from controls and patients with megaloblastic anaemia: the effect of therapy.
    British journal of haematology, 1978, Volume: 38, Issue:3

    Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Anemia, Pernicious; Folic Acid; Folic Acid Deficiency; Fo

1978
The effect of methionine on the metabolism of serine and glycine in vitamin B-12-deficient rats.
    Biochimica et biophysica acta, 1975, Aug-13, Volume: 399, Issue:2

    Topics: Animals; Folic Acid Deficiency; Glycine; Liver; Male; Methionine; Perfusion; Rats; Serine; Vitamin B

1975
Defective leukocyte metabolism in human cobalamin deficiency: impaired propionate oxidation and serine biosynthesis reversible by cyanocobalamin therapy.
    The Journal of laboratory and clinical medicine, 1976, Volume: 87, Issue:1

    Topics: Adult; Aged; Anemia, Pernicious; Female; Folic Acid; Folic Acid Deficiency; Humans; Leukocyte Count;

1976
Tissue folates in fruit bats (Rousettus aegyptiacus) with nitrous oxide-induced vitamin B12 deficiency and neurological impairment.
    The British journal of nutrition, 1987, Volume: 58, Issue:3

    Topics: Animals; Brain; Chiroptera; Folic Acid; Liver; Methionine; Nervous System Diseases; Nitrous Oxide; S

1987
Folated deficiency in pernicious anemia measured by determination of decreased serine synthesis in lymphocytes.
    British journal of haematology, 1973, Volume: 24, Issue:5

    Topics: Adolescent; Adult; Aged; Anemia, Pernicious; Blood Proteins; Carbon Isotopes; Female; Folic Acid; Fo

1973
Selective malabsorption of vitamin B 12: report of a case with metabolic studies.
    American journal of diseases of children (1960), 1974, Volume: 127, Issue:5

    Topics: Alanine; Amino Acids; Anemia, Macrocytic; Child; Chromatography, Gas; Glycine; Hemoglobins; Histidin

1974
The oxidation of the beta carbon of serine in human folate and vitamin B 12 deficiency.
    The Journal of laboratory and clinical medicine, 1972, Volume: 80, Issue:3

    Topics: Anemia, Macrocytic; Carbon; Carbon Dioxide; Carbon Isotopes; Diet; Erythrocyte Count; Folic Acid; Fo

1972
Methylation of t-RNA: effect of vitamin B 12 deficiency in rat.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1967, Volume: 124, Issue:1

    Topics: Alkylation; Animals; Escherichia coli; In Vitro Techniques; Liver; Methionine; Rats; RNA, Transfer;

1967
Vitamin B12 deficiency in the rat fed high protein rations.
    The Journal of nutrition, 1971, Volume: 101, Issue:5

    Topics: Amino Acids; Animals; Caseins; Depression, Chemical; Dietary Proteins; Formates; Glycine; Growth; Is

1971
Incorporation of [14C] amino acids into liver S-RNA of chick. Effect of orotic acid and vitamin B12.
    Experientia, 1966, Jul-15, Volume: 22, Issue:7

    Topics: Amino Acids; Animals; Carbon Isotopes; In Vitro Techniques; Leucine; Liver; Methionine; Orotic Acid;

1966