Page last updated: 2024-11-08

serine and Cystic Fibrosis

serine has been researched along with Cystic Fibrosis in 14 studies

Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.

Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.14)18.7374
1990's6 (42.86)18.2507
2000's3 (21.43)29.6817
2010's4 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rimessi, A1
Bezzerri, V1
Salvatori, F1
Tamanini, A1
Nigro, F1
Dechecchi, MC1
Santangelo, A1
Prandini, P1
Munari, S1
Provezza, L1
Garreau de Loubresse, N1
Muller, J1
Ribeiro, CMP1
Lippi, G1
Gambari, R1
Pinton, P1
Cabrini, G1
Venerando, A1
Cesaro, L1
Marin, O1
Donella-Deana, A1
Pinna, LA1
René, C1
Paulet, D1
Girodon, E1
Costa, C1
Lalau, G1
Leclerc, J1
Cabet-Bey, F1
Bienvenu, T2
Blayau, M1
Iron, A1
Mittre, H1
Feldmann, D1
Guittard, C1
Claustres, M1
Georges, Md1
McClure, M1
DeLucas, LJ1
Wilson, L1
Ray, M1
Rowe, SM1
Wu, X1
Dai, Q1
Hong, JS1
Sorscher, EJ1
Kappes, JC1
Barnes, S1
Erickson, DL1
Lines, JL1
Pesci, EC1
Venturi, V1
Storey, DG1
Kraus, C1
Reis, A1
Naehrlich, L1
Dötsch, J1
Korbmacher, C1
Rauh, R1
Rich, DP1
Berger, HA1
Cheng, SH1
Travis, SM1
Saxena, M1
Smith, AE1
Welsh, MJ1
Schaedel, C1
Andersson, AM1
Kristoffersson, AC1
Kornfält, R1
Lannefors, L1
Holmberg, L1
Pasyk, EA1
Morin, XK1
Zeman, P1
Garami, E1
Galley, K1
Huan, LJ1
Wang, Y1
Bear, CE1
Cartault, F1
Steffann, J1
Vidaud, D1
Bousquet, S1
Lesure, F1
Renouil, M1
McDonell, N1
Feingold, J1
Beldjord, C1
Monaghan, KG1
Feldman, GL1
Barbarotto, GM1
Manji, S1
Desai, TK1
Snow, K1
Lissens, W1
Bonduelle, M1
Malfroot, A1
Dab, I1
Liebaers, I1
Sangiuolo, F1
Novelli, G1
Murru, S1
Dallapiccola, B1
Roussel, P1
Lamblin, G1
Degand, P1
Havez, R1

Other Studies

14 other studies available for serine and Cystic Fibrosis

ArticleYear
PLCB3 Loss of Function Reduces Pseudomonas aeruginosa-Dependent IL-8 Release in Cystic Fibrosis.
    American journal of respiratory cell and molecular biology, 2018, Volume: 59, Issue:4

    Topics: Bronchi; Calcium Signaling; Cell Line; Computer Simulation; Cystic Fibrosis; Humans; Interleukin-8;

2018
A "SYDE" effect of hierarchical phosphorylation: possible relevance to the cystic fibrosis basic defect.
    Cellular and molecular life sciences : CMLS, 2014, Volume: 71, Issue:12

    Topics: Amino Acid Sequence; Aspartic Acid; Casein Kinase II; Consensus Sequence; Cystic Fibrosis; Cystic Fi

2014
p.Ser1235Arg should no longer be considered as a cystic fibrosis mutation: results from a large collaborative study.
    European journal of human genetics : EJHG, 2011, Volume: 19, Issue:1

    Topics: Amino Acid Sequence; Arginine; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator;

2011
Purification of CFTR for mass spectrometry analysis: identification of palmitoylation and other post-translational modifications.
    Protein engineering, design & selection : PEDS, 2012, Volume: 25, Issue:1

    Topics: Amino Acid Sequence; Binding Sites; Blotting, Western; Chromatography, Liquid; Cystic Fibrosis; Cyst

2012
Pseudomonas aeruginosa relA contributes to virulence in Drosophila melanogaster.
    Infection and immunity, 2004, Volume: 72, Issue:10

    Topics: Amino Acids; Animals; Bacterial Proteins; Cystic Fibrosis; Drosophila melanogaster; Guanosine Pentap

2004
Functional characterization of a novel CFTR mutation P67S identified in a patient with atypical cystic fibrosis.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2007, Volume: 19, Issue:5-6

    Topics: Action Potentials; Adolescent; Amino Acid Substitution; Base Sequence; Cystic Fibrosis; Cystic Fibro

2007
Regulation of the cystic fibrosis transmembrane conductance regulator Cl- channel by negative charge in the R domain.
    The Journal of biological chemistry, 1993, Sep-25, Volume: 268, Issue:27

    Topics: Alanine; Amino Acid Sequence; Animals; Autoradiography; Cell Line; Chloride Channels; Cystic Fibrosi

1993
Mild cystic fibrosis mutations in Southern Sweden with special reference to S549I and T338I.
    Clinical genetics, 1998, Volume: 53, Issue:5

    Topics: Adolescent; Adult; Age of Onset; Alleles; Amino Acid Substitution; Child; Child, Preschool; Cystic F

1998
A conserved region of the R domain of cystic fibrosis transmembrane conductance regulator is important in processing and function.
    The Journal of biological chemistry, 1998, Nov-27, Volume: 273, Issue:48

    Topics: Amino Acid Sequence; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line; Ce

1998
Detection of more than 91% cystic fibrosis mutations in a sample of the population from Reunion Island and identification of two novel mutations (A309G, S1255L) and one novel polymorphism (L49L)
    Clinical genetics, 1998, Volume: 54, Issue:5

    Topics: Alanine; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; France; Glycine; Huma

1998
Frequency and clinical significance of the S1235R mutation in the cystic fibrosis transmembrane conductance regulator gene: results from a collaborative study.
    American journal of medical genetics, 2000, Dec-11, Volume: 95, Issue:4

    Topics: Adolescent; Adult; Aged; Amino Acid Substitution; Arginine; Child; Child, Preschool; Cystic Fibrosis

2000
A serine to proline substitution (S1255P) in the second nucleotide binding fold of the cystic fibrosis gene.
    Human molecular genetics, 1992, Volume: 1, Issue:6

    Topics: Adenosine Triphosphate; Base Sequence; Binding Sites; Cystic Fibrosis; Cystic Fibrosis Transmembrane

1992
A serine-to-arginine (AGT-to-CGT) mutation in codon 549 of the CFTR gene in an Italian patient with severe cystic fibrosis.
    Genomics, 1991, Volume: 9, Issue:4

    Topics: Arginine; Base Sequence; Codon; Cystic Fibrosis; DNA; Exons; Female; Humans; Male; Molecular Sequenc

1991
[Isolation of bronchial mucins secreted in cystic fibrosis].
    Clinica chimica acta; international journal of clinical chemistry, 1972, Volume: 36, Issue:2

    Topics: Animals; Bronchi; Child; Chromatography, Gel; Chromatography, Ion Exchange; Cystic Fibrosis; Electro

1972