serine has been researched along with Cryptogenic Infantile Spasms in 7 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with oral L-serine abolished seizures and improved psychomotor development, hyperexcitability, head growth, cortical and subcortical hypotrophy, and hypomyelination of the brain on MRI scans." | 1.31 | 3-phosphoglycerate dehydrogenase deficiency in a patient with West syndrome. ( Aracil, A; Artuch, R; García González, MM; Jaeken, J; Pineda, M; Santos, S; Van Schaftingen, E; Vilaseca, MA, 2000) |
| " An adverse effect of high-dose serine therapy on head growth and on the transport of neutral amino acids across the blood-brain barrier should be considered and requires adjustment of treatment." | 1.31 | Phenotypic heterogeneity and adverse effects of serine treatment in 3-phosphoglycerate dehydrogenase deficiency: report on two siblings. ( Häusler, MG; Jaeken, J; Mönch, E; Ramaekers, VT, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 3 (42.86) | 2.80 |
| Authors | Studies |
|---|---|
| Fuchs, C | 1 |
| Cosentino, L | 1 |
| Urbinati, C | 1 |
| Talamo, MC | 1 |
| Medici, G | 1 |
| Quattrini, MC | 1 |
| Mottolese, N | 1 |
| Pietraforte, D | 1 |
| Fuso, A | 1 |
| Ciani, E | 1 |
| De Filippis, B | 1 |
| Colarusso, A | 1 |
| Lauro, C | 1 |
| Calvanese, M | 1 |
| Parrilli, E | 1 |
| Tutino, ML | 1 |
| Jiang, M | 1 |
| Xu, Q | 1 |
| Yang, C | 1 |
| Li, D | 1 |
| Liu, JW | 1 |
| Zhang, Y | 1 |
| Zhu, YC | 1 |
| Xiong, ZQ | 1 |
| de Koning, TJ | 1 |
| Poll-The, BT | 1 |
| Jaeken, J | 3 |
| Pineda, M | 1 |
| Vilaseca, MA | 1 |
| Artuch, R | 1 |
| Santos, S | 1 |
| García González, MM | 1 |
| Aracil, A | 1 |
| Van Schaftingen, E | 1 |
| Häusler, MG | 1 |
| Mönch, E | 1 |
| Ramaekers, VT | 1 |
| Furuya, S | 1 |
| Mitoma, J | 1 |
| Hirabayashi, Y | 1 |
2 reviews available for serine and Cryptogenic Infantile Spasms
| Article | Year |
|---|---|
Continuing education in neurometabolic disorders--serine deficiency disorders.
Topics: Adolescent; Amino Acids; Child; Deficiency Diseases; Female; Glycine; Humans; Ichthyosis; Male; Meta | 1999 |
[Glia-derived L-Ser regulating survival development and lipid synthesis of developing central neurons].
Topics: Animals; Astrocytes; Brain; Carbohydrate Dehydrogenases; Gene Expression Regulation, Enzymologic; Hu | 2002 |
5 other studies available for serine and Cryptogenic Infantile Spasms
| Article | Year |
|---|---|
Treatment with FRAX486 rescues neurobehavioral and metabolic alterations in a female mouse model of CDKL5 deficiency disorder.
Topics: Animals; Disease Models, Animal; Disks Large Homolog 4 Protein; Epileptic Syndromes; Female; Glucose | 2022 |
Active human full-length CDKL5 produced in the Antarctic bacterium Pseudoalteromonas haloplanktis TAC125.
Topics: Antarctic Regions; Cold Temperature; Epileptic Syndromes; Humans; Peptide Hydrolases; Protein Kinase | 2022 |
Activity-Dependent Phosphorylation of CDKL5 at Serine 407 Regulates Synaptogenesis and Plasticity.
Topics: Humans; Phosphorylation; Protein Serine-Threonine Kinases; Serine; Spasms, Infantile | 2023 |
3-phosphoglycerate dehydrogenase deficiency in a patient with West syndrome.
Topics: Brain; Carbohydrate Dehydrogenases; Electroencephalography; Failure to Thrive; Female; Humans; Infan | 2000 |
Phenotypic heterogeneity and adverse effects of serine treatment in 3-phosphoglycerate dehydrogenase deficiency: report on two siblings.
Topics: Amino Acids; Carbohydrate Dehydrogenases; Cerebrospinal Fluid; Child; Child, Preschool; Dose-Respons | 2001 |