Page last updated: 2024-11-08

serine and Coronary Disease

serine has been researched along with Coronary Disease in 12 studies

Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.

Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.

Research Excerpts

ExcerptRelevanceReference
"A single nucleotide polymorphism that substitutes a serine for an asparagine at residue 700 in the Ca2+-binding repeats of thrombospondin-1 is associated with familial premature coronary heart disease."3.72A polymorphism in thrombospondin-1 associated with familial premature coronary heart disease causes a local change in conformation of the Ca2+-binding repeats. ( Annis, DS; Hannah, BL; Misenheimer, TM; Mosher, DF, 2003)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (25.00)18.2507
2000's8 (66.67)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jelassi, A1
Jguirim, I1
Slimani, A1
Najah, M1
Hamda, KB1
Addad, F1
Hassine, M1
Maatouk, F1
Varret, M1
Slimane, MN1
Pan, JP1
Lai, ST1
Chiang, SC1
Chou, SC1
Chiang, AN1
Hannah, BL1
Misenheimer, TM1
Annis, DS1
Mosher, DF1
Liu, H1
Zhang, S1
Lin, J1
Li, H1
Huang, A1
Xiao, C1
Li, X1
Su, Z1
Wang, C1
Nebert, DW1
Zhou, B1
Zheng, K1
Shi, J1
Li, G1
Huang, D1
Hu, Y1
Liu, W1
Huang, R1
Zhang, X1
Talmud, PJ1
Flavell, DM1
Alfakih, K1
Cooper, JA1
Balmforth, AJ1
Sivananthan, M1
Montgomery, HE1
Hall, AS1
Humphries, SE1
März, W1
Seelhorst, U1
Wellnitz, B1
Tiran, B1
Obermayer-Pietsch, B1
Renner, W1
Boehm, BO1
Ritz, E1
Hoffmann, MM1
Oho, S1
Rabinovitch, M1
Ye, SQ1
Usher, D1
Virgil, D1
Zhang, LQ1
Yochim, SE1
Gupta, R1
Gagné, SE1
Larson, MG1
Pimstone, SN1
Schaefer, EJ1
Kastelein, JJ1
Wilson, PW1
Ordovas, JM1
Hayden, MR1
Pulkkinen, A1
Viitanen, L1
Kareinen, A1
Lehto, S1
Laakso, M1
Rauchhaus, M1
Gross, M1
Schulz, S1
Francis, DP1
Greiser, P1
Norwig, A1
Weidhase, L1
Coats, AJ1
Dietz, R1
Anker, SD1
Gläser, C1

Reviews

1 review available for serine and Coronary Disease

ArticleYear
A systematic review and meta-analysis of the relationship between lipoprotein lipase Asn291Ser variant and diseases.
    Journal of lipid research, 2006, Volume: 47, Issue:9

    Topics: Amino Acid Substitution; Asparagine; Coronary Disease; Diabetes Mellitus, Type 2; Dyslipidemias; Hum

2006

Other Studies

11 other studies available for serine and Coronary Disease

ArticleYear
[Association between variants of lipoprotein lipase and coronary heart disease in a Tunisian population].
    Pathologie-biologie, 2012, Volume: 60, Issue:3

    Topics: Aged; Amino Acid Substitution; Asparagine; Aspartic Acid; Case-Control Studies; Coronary Disease; Fe

2012
The risk of coronary artery disease in population of Taiwan is associated with Cys-Ser 311 polymorphism of human paraoxonase (PON)-2 gene.
    Zhonghua yi xue za zhi = Chinese medical journal; Free China ed, 2002, Volume: 65, Issue:9

    Topics: Adult; Aged; Aryldialkylphosphatase; Coronary Disease; Cysteine; Esterases; Female; Genetic Predispo

2002
A polymorphism in thrombospondin-1 associated with familial premature coronary heart disease causes a local change in conformation of the Ca2+-binding repeats.
    The Journal of biological chemistry, 2003, Mar-14, Volume: 278, Issue:11

    Topics: Calcium; Circular Dichroism; Cloning, Molecular; Coronary Disease; Dose-Response Relationship, Drug;

2003
Association between DNA variant sites in the apolipoprotein A5 gene and coronary heart disease in Chinese.
    Metabolism: clinical and experimental, 2005, Volume: 54, Issue:5

    Topics: Apolipoprotein A-V; Apolipoproteins; Apolipoproteins A; Asian People; Case-Control Studies; Choleste

2005
The lipoprotein lipase gene serine 447 stop variant influences hypertension-induced left ventricular hypertrophy and risk of coronary heart disease.
    Clinical science (London, England : 1979), 2007, Volume: 112, Issue:12

    Topics: Adult; Apolipoproteins; Coronary Disease; Fatty Acids; Female; Gene Frequency; Genotype; Homozygote;

2007
Alanine to serine polymorphism at position 986 of the calcium-sensing receptor associated with coronary heart disease, myocardial infarction, all-cause, and cardiovascular mortality.
    The Journal of clinical endocrinology and metabolism, 2007, Volume: 92, Issue:6

    Topics: Adult; Aged; Alanine; Calcium; Cause of Death; Coronary Angiography; Coronary Disease; Female; Genet

2007
Post-cardiac transplant arteriopathy in piglets is associated with fragmentation of elastin and increased activity of a serine elastase.
    The American journal of pathology, 1994, Volume: 145, Issue:1

    Topics: Animals; Coronary Disease; Elastin; Heart Transplantation; Microscopy, Electron; Pancreatic Elastase

1994
A PstI polymorphism detects the mutation of serine128 to arginine in CD 62E gene - a risk factor for coronary artery disease.
    Journal of biomedical science, 1999, Volume: 6, Issue:1

    Topics: Alleles; Amino Acid Substitution; Angiography; Arginine; Coronary Disease; Deoxyribonucleases, Type

1999
A common truncation variant of lipoprotein lipase (Ser447X) confers protection against coronary heart disease: the Framingham Offspring Study.
    Clinical genetics, 1999, Volume: 55, Issue:6

    Topics: Adult; Aged; Alleles; Cohort Studies; Coronary Disease; Female; Gene Deletion; Gene Frequency; Genet

1999
Gly82Ser polymorphism of the receptor of advanced glycation end product gene is not associated with coronary heart disease in Finnish nondiabetic subjects or in patients with type 2 diabetes.
    Diabetes care, 2000, Volume: 23, Issue:6

    Topics: Amino Acid Substitution; Coronary Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female;

2000
The E-selectin SER128ARG gene polymorphism and restenosis after successful coronary angioplasty.
    International journal of cardiology, 2002, Volume: 83, Issue:3

    Topics: Angioplasty, Balloon, Coronary; Arginine; Coronary Angiography; Coronary Disease; Coronary Restenosi

2002