serine has been researched along with Coronary Artery Disease in 14 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Coronary Artery Disease: Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Leonurine has been shown to have excellent anti-myocardial ischemia effects." | 8.12 | Cardioprotective Mechanism of Leonurine against Myocardial Ischemia through a Liver-Cardiac Crosstalk Metabolomics Study. ( Li, J; Lu, Q; Pan, D; Rong, W; Wang, A; Wang, L; Zhang, Y; Zhou, Q; Zhu, Q; Zhu, Y, 2022) |
| "In the European population, alanine and serine were inversely associated with angina pectoris (AP) and chronic heart failure, respectively." | 4.31 | Causal relationships of circulating amino acids with cardiovascular disease: a trans-ancestry Mendelian randomization analysis. ( Guo, TT; Hu, MJ; Hu, S; Hua, L; Huang, X; Lin, Z; Tan, JS, 2023) |
| "Leonurine has been shown to have excellent anti-myocardial ischemia effects." | 4.12 | Cardioprotective Mechanism of Leonurine against Myocardial Ischemia through a Liver-Cardiac Crosstalk Metabolomics Study. ( Li, J; Lu, Q; Pan, D; Rong, W; Wang, A; Wang, L; Zhang, Y; Zhou, Q; Zhu, Q; Zhu, Y, 2022) |
| "A single nucleotide polymorphism that results in substitution at residue 700 of a serine (Ser-700) for an asparagine (Asn-700) in thrombospondin-1 is associated with familial premature coronary artery disease." | 3.72 | A polymorphism in thrombospondin-1 associated with familial premature coronary artery disease alters Ca2+ binding. ( Hannah, BL; Misenheimer, TM; Mosher, DF; Pranghofer, MM, 2004) |
| "Two common coding sequence mutations of lipoprotein lipase (serine447-ter, producing a carboxy terminal truncation; and asp9-asn variants) were studied in 329 Caucasian subjects, of whom 243 had angiographic features of premature atheroscelerosis (220 with coronary artery disease; 23 with coronary and peripheral artery disease)." | 3.69 | Common genetic variants of lipoprotein lipase that relate to lipid transport in patients with premature coronary artery disease. ( Cavanna, J; Galton, DJ; Gross, W; Marz, W; Shine, B; Winkelman, BR; Zhang, Q, 1995) |
| " Additionally, anti-miR-93 and anti-miR-484 restore KLF2 and eNOS expression and NO bioavailability in ECs under OS." | 1.51 | Shear stress regulation of miR-93 and miR-484 maturation through nucleolin. ( Chen, L; Chen, S; Chien, S; Gongol, B; Han, Y; He, M; Huang, PH; Johnson, DA; Kang, J; Li, J; Li, YS; Liu, JH; Lytle, C; Marin, T; Martin, M; Shyy, JY; Sun, W; Wang, SC; Zhang, J, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 6 (42.86) | 24.3611 |
| 2020's | 3 (21.43) | 2.80 |
| Authors | Studies |
|---|---|
| Rong, W | 1 |
| Li, J | 2 |
| Pan, D | 1 |
| Zhou, Q | 1 |
| Zhang, Y | 2 |
| Lu, Q | 1 |
| Wang, L | 1 |
| Wang, A | 1 |
| Zhu, Y | 1 |
| Zhu, Q | 1 |
| Pan, H | 1 |
| Guo, Z | 2 |
| Lv, P | 1 |
| Hu, K | 1 |
| Wu, T | 1 |
| Lin, Z | 2 |
| Xue, Y | 1 |
| Hu, S | 1 |
| Hu, MJ | 1 |
| Tan, JS | 1 |
| Guo, TT | 1 |
| Huang, X | 1 |
| Hua, L | 1 |
| Gongol, B | 1 |
| Marin, T | 1 |
| Zhang, J | 1 |
| Wang, SC | 1 |
| Sun, W | 1 |
| He, M | 1 |
| Chen, S | 1 |
| Chen, L | 1 |
| Liu, JH | 1 |
| Martin, M | 1 |
| Han, Y | 1 |
| Kang, J | 1 |
| Johnson, DA | 1 |
| Lytle, C | 1 |
| Li, YS | 1 |
| Huang, PH | 1 |
| Chien, S | 1 |
| Shyy, JY | 1 |
| Li, Y | 1 |
| Xu, S | 1 |
| Jiang, B | 1 |
| Cohen, RA | 1 |
| Zang, M | 1 |
| Wang, CL | 1 |
| Lin, TH | 1 |
| Lin, HY | 1 |
| Sheu, SH | 1 |
| Yu, ML | 1 |
| Hsiao, PJ | 1 |
| Lin, KD | 1 |
| Hsu, C | 1 |
| Yang, YH | 1 |
| Shin, SJ | 1 |
| Mälarstig, A | 1 |
| Silveira, A | 1 |
| Wågsäter, D | 1 |
| Öhrvik, J | 1 |
| Bäcklund, A | 1 |
| Samnegård, A | 1 |
| Khademi, M | 1 |
| Hellenius, ML | 1 |
| Leander, K | 1 |
| Olsson, T | 1 |
| Uhlén, M | 1 |
| de Faire, U | 1 |
| Eriksson, P | 1 |
| Hamsten, A | 1 |
| Geloneze, SR | 1 |
| Geloneze, B | 1 |
| Morari, J | 1 |
| Matos-Souza, JR | 1 |
| Lima, MM | 1 |
| Chaim, EA | 1 |
| Pareja, JC | 1 |
| Velloso, LA | 1 |
| Kucukhuseyin, O | 1 |
| Yilmaz-Aydogan, H | 1 |
| Isbir, CS | 1 |
| Isbir, T | 1 |
| Hannah, BL | 1 |
| Misenheimer, TM | 1 |
| Pranghofer, MM | 1 |
| Mosher, DF | 1 |
| Martinelli, N | 1 |
| Trabetti, E | 1 |
| Bassi, A | 1 |
| Girelli, D | 1 |
| Friso, S | 1 |
| Pizzolo, F | 1 |
| Sandri, M | 1 |
| Malerba, G | 1 |
| Pignatti, PF | 1 |
| Corrocher, R | 1 |
| Olivieri, O | 1 |
| Zhang, Q | 1 |
| Cavanna, J | 1 |
| Winkelman, BR | 1 |
| Shine, B | 1 |
| Gross, W | 1 |
| Marz, W | 1 |
| Galton, DJ | 1 |
| Nordestgaard, BG | 1 |
| Abildgaard, S | 1 |
| Wittrup, HH | 1 |
| Steffensen, R | 1 |
| Jensen, G | 1 |
| Tybjaerg-Hansen, A | 1 |
| Chen, W | 1 |
| Srinivasan, SR | 1 |
| Elkasabany, A | 1 |
| Ellsworth, DL | 1 |
| Boerwinkle, E | 1 |
| Berenson, GS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Bogalusa Heart Study[NCT00005129] | 11,737 participants (Actual) | Observational | 1972-06-30 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
14 other studies available for serine and Coronary Artery Disease
| Article | Year |
|---|---|
Cardioprotective Mechanism of Leonurine against Myocardial Ischemia through a Liver-Cardiac Crosstalk Metabolomics Study.
Topics: Amino Acids; Animals; Coronary Artery Disease; Fatty Acids; Glycine; Liver; Metabolomics; Myocardial | 2022 |
Proline/serine-rich coiled-coil protein 1 inhibits macrophage inflammation and delays atherosclerotic progression by binding to Annexin A2.
Topics: Animals; Annexin A2; Atherosclerosis; Coronary Artery Disease; Inflammation; Macrophages; Mice; Mice | 2023 |
Causal relationships of circulating amino acids with cardiovascular disease: a trans-ancestry Mendelian randomization analysis.
Topics: Amino Acids; Angina Pectoris; Cardiovascular Diseases; Coronary Artery Disease; Genome-Wide Associat | 2023 |
Shear stress regulation of miR-93 and miR-484 maturation through nucleolin.
Topics: Adult; Aged; AMP-Activated Protein Kinases; Animals; Case-Control Studies; Cells, Cultured; Computat | 2019 |
Activation of sterol regulatory element binding protein and NLRP3 inflammasome in atherosclerotic lesion development in diabetic pigs.
Topics: Acetylation; AMP-Activated Protein Kinases; Animals; Aorta; Atherosclerosis; Biomarkers; Carrier Pro | 2013 |
The 8-oxoguanine glycosylase I (hOGG1) Ser326Cys variant affects the susceptibility to multi-vessel disease in Taiwan coronary artery disease patients.
Topics: Aged; Coronary Artery Disease; Cysteine; DNA Glycosylases; Genotype; Humans; Male; Middle Aged; Poly | 2010 |
Plasma CD93 concentration is a potential novel biomarker for coronary artery disease.
Topics: Aged; Biomarkers; Case-Control Studies; Coronary Artery Disease; Enzyme-Linked Immunosorbent Assay; | 2011 |
PGC1α gene Gly482Ser polymorphism predicts improved metabolic, inflammatory and vascular outcomes following bariatric surgery.
Topics: Adolescent; Adult; Brazil; C-Reactive Protein; Carotid Intima-Media Thickness; Comorbidity; Coronary | 2012 |
Is there any association between GLY82 ser polymorphism of rage gene and Turkish diabetic and non diabetic patients with coronary artery disease?
Topics: Coronary Artery Disease; Demography; Diabetes Complications; Female; Gene Frequency; Genetic Associa | 2012 |
A polymorphism in thrombospondin-1 associated with familial premature coronary artery disease alters Ca2+ binding.
Topics: Amino Acid Motifs; Amino Acid Sequence; Asparagine; Binding Sites; Calcium; Coronary Artery Disease; | 2004 |
The -1131 T>C and S19W APOA5 gene polymorphisms are associated with high levels of triglycerides and apolipoprotein C-III, but not with coronary artery disease: an angiographic study.
Topics: Adult; Aged; Apolipoprotein A-V; Apolipoprotein C-III; Apolipoproteins A; Coronary Angiography; Coro | 2007 |
Common genetic variants of lipoprotein lipase that relate to lipid transport in patients with premature coronary artery disease.
Topics: Asparagine; Aspartic Acid; Coronary Artery Disease; Genetic Variation; Humans; Lipid Metabolism; Lip | 1995 |
Heterozygous lipoprotein lipase deficiency: frequency in the general population, effect on plasma lipid levels, and risk of ischemic heart disease.
Topics: Adult; Aged; Aged, 80 and over; Apolipoprotein A-I; Asparagine; Cholesterol, HDL; Coronary Artery Di | 1997 |
Influence of lipoprotein lipase serine 447 stop polymorphism on tracking of triglycerides and HDL cholesterol from childhood to adulthood and familial risk of coronary artery disease: the Bogalusa heart study.
Topics: Adolescent; Adult; Cholesterol, HDL; Coronary Artery Disease; Cross-Sectional Studies; Data Collecti | 2001 |