serine has been researched along with Colorectal Neoplasms, Hereditary Nonpolyposis in 4 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Colorectal Neoplasms, Hereditary Nonpolyposis: A group of autosomal-dominant inherited diseases in which COLON CANCER arises in discrete adenomas. Unlike FAMILIAL POLYPOSIS COLI with hundreds of polyps, hereditary nonpolyposis colorectal neoplasms occur much later, in the fourth and fifth decades. HNPCC has been associated with germline mutations in mismatch repair (MMR) genes. It has been subdivided into Lynch syndrome I or site-specific colonic cancer, and LYNCH SYNDROME II which includes extracolonic cancer.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Raevaara, TE | 1 |
| Gerdes, AM | 1 |
| Lönnqvist, KE | 1 |
| Tybjaerg-Hansen, A | 1 |
| Abdel-Rahman, WM | 1 |
| Kariola, R | 1 |
| Peltomäki, P | 1 |
| Nyström-Lahti, M | 1 |
| Vernez, M | 1 |
| Hutter, P | 1 |
| Monnerat, C | 1 |
| Halkic, N | 1 |
| Gugerli, O | 1 |
| Bouzourene, H | 1 |
| Bianchi, F | 1 |
| Galizia, E | 1 |
| Porfiri, E | 1 |
| Belvederesi, L | 1 |
| Catalani, R | 1 |
| Loretelli, C | 1 |
| Bracci, R | 1 |
| Bearzi, I | 1 |
| Turchi, C | 1 |
| Viel, A | 1 |
| Cellerino, R | 1 |
| Ollila, S | 1 |
| Dermadi Bebek, D | 1 |
| Greenblatt, M | 1 |
| Nyström, M | 1 |
4 other studies available for serine and Colorectal Neoplasms, Hereditary Nonpolyposis
| Article | Year |
|---|---|
HNPCC mutation MLH1 P648S makes the functional protein unstable, and homozygosity predisposes to mild neurofibromatosis type 1.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Substitution; Carrier Proteins; Cell Line, Tumor; C | 2004 |
A case of Muir-Torre syndrome associated with mucinous hepatic cholangiocarcinoma and a novel germline mutation of the MSH2 gene.
Topics: Adenocarcinoma, Mucinous; Adenoma; Adult; Brain Neoplasms; Carcinoma; Cholangiocarcinoma; Colorectal | 2007 |
A missense germline mutation in exon 7 of the MSH2 gene in a HNPCC family from center-Italy.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Arginine; Colorectal Neopla | 2007 |
Uncertain pathogenicity of MSH2 variants N127S and G322D challenges their classification.
Topics: Asparagine; Aspartic Acid; Biliary Tract Neoplasms; Blotting, Western; Colorectal Neoplasms, Heredit | 2008 |