serine has been researched along with Chronic Pain in 2 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Chronic Pain: Aching sensation that persists for more than a few months. It may or may not be associated with trauma or disease, and may persist after the initial injury has healed. Its localization, character, and timing are more vague than with acute pain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The amygdala is implicated in chronic pain-induced emotional changes." | 5.38 | Functional roles of endogenous D-serine in the chronic pain-induced plasticity of NMDAR-mediated synaptic transmission in the central amygdala of mice. ( Hori, Y; Huse, N; Konno, R; Maekawa, M; Wakamatsu, S, 2012) |
| " The study period consisted of 8-wk dosing and 4-wk posttreatment observation." | 2.94 | l-Serine and EPA Relieve Chronic Low-Back and Knee Pain in Adults: A Randomized, Double-Blind, Placebo-Controlled Trial. ( Hashimoto, M; Kobuna, Y; Mine, T; Nagao, K; Nishikata, N; Sasahara, I; Suga, Y; Suzuki, K; Takada, M; Takeshita, M; Yamamoto, A, 2020) |
| "The amygdala is implicated in chronic pain-induced emotional changes." | 1.38 | Functional roles of endogenous D-serine in the chronic pain-induced plasticity of NMDAR-mediated synaptic transmission in the central amygdala of mice. ( Hori, Y; Huse, N; Konno, R; Maekawa, M; Wakamatsu, S, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sasahara, I | 1 |
| Yamamoto, A | 1 |
| Takeshita, M | 1 |
| Suga, Y | 1 |
| Suzuki, K | 1 |
| Nishikata, N | 1 |
| Takada, M | 1 |
| Hashimoto, M | 1 |
| Mine, T | 1 |
| Kobuna, Y | 1 |
| Nagao, K | 1 |
| Maekawa, M | 1 |
| Wakamatsu, S | 1 |
| Huse, N | 1 |
| Konno, R | 1 |
| Hori, Y | 1 |
1 trial available for serine and Chronic Pain
| Article | Year |
|---|---|
l-Serine and EPA Relieve Chronic Low-Back and Knee Pain in Adults: A Randomized, Double-Blind, Placebo-Controlled Trial.
Topics: Adult; Back Pain; Chronic Pain; Double-Blind Method; Eicosapentaenoic Acid; Female; Humans; Knee Joi | 2020 |
1 other study available for serine and Chronic Pain
| Article | Year |
|---|---|
Functional roles of endogenous D-serine in the chronic pain-induced plasticity of NMDAR-mediated synaptic transmission in the central amygdala of mice.
Topics: Amygdala; Animals; Chronic Pain; Mice; Mice, Knockout; Neuronal Plasticity; Patch-Clamp Techniques; | 2012 |