Page last updated: 2024-11-08

serine and Chromosomal Translocation

serine has been researched along with Chromosomal Translocation in 20 studies

Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
"ARMS is characterized by a t(2;13) chromosomal translocation resulting in the fusion of the 5' Pax3 sequences to the 3' FOXO1 sequences to encode the oncogenic fusion protein, Pax3-FOXO1."1.35Phosphorylation of serine 205 by the protein kinase CK2 persists on Pax3-FOXO1, but not Pax3, throughout early myogenic differentiation. ( Dietz, KN; Hollenbach, AD; Miller, PJ, 2009)
"The t(4;11) chromosomal translocation marks a subset of acute lymphoblastic and secondary myeloid leukemias."1.30The FEL (AF-4) protein donates transcriptional activation sequences to Hrx-Fel fusion proteins in leukemias containing T(4;11)(Q21;Q23) chromosomal translocations. ( Cleary, ML; Morrissey, JJ; Raney, S, 1997)
"[1996: Am J Med Genet 66:138-143] as Pfeiffer syndrome type III with normal thumbs."1.30Phenotype of the fibroblast growth factor receptor 2 Ser351Cys mutation: Pfeiffer syndrome type III. ( Bartlett, SP; Gripp, KW; Katowitz, JA; Markowitz, RI; McDonald-McGinn, DM; Muenke, M; Stolle, CA; Zackai, EH, 1998)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.00)18.7374
1990's4 (20.00)18.2507
2000's11 (55.00)29.6817
2010's3 (15.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Zhan, P1
Hao, T1
Yang, X2
Zhang, Y1
Fioretti, T1
Cevenini, A1
Zanobio, M1
Raia, M1
Sarnataro, D1
Salvatore, F1
Esposito, G1
Sun, Y1
Cao, A1
Wang, X1
Chen, P1
Li, AY1
Boo, LM1
Wang, SY1
Lin, HH1
Wang, CC1
Yen, Y1
Chen, BP1
Chen, DJ1
Ann, DK1
Dietz, KN1
Miller, PJ1
Hollenbach, AD1
Oshima, T1
Fujino, T1
Ando, K1
Hayakawa, M1
Ozeki, Y1
Pickard, BS1
Kano, S1
Malloy, MP1
Zeledon, M1
Sun, DQ1
Fujii, K1
Wakui, K1
Shirayama, Y1
Fukushima, Y1
Kunugi, H1
Hashimoto, K1
Muir, WJ1
Blackwood, DH1
Sawa, A1
Nguyen, TA1
Boyle, DL1
Wagner, LM1
Shinohara, T1
Takemoto, DJ1
Jo, EJ1
Lee, HY1
Kim, JI1
Kang, HK1
Lee, YN1
Kwak, JY1
Bae, YS1
Lausen, J1
Cho, S1
Liu, S1
Werner, MH1
Mirandola, P1
Ponti, C1
Gobbi, G1
Sponzilli, I1
Melloni, E1
Vitale, M1
Kang, J1
Ferguson, D1
Song, H1
Bassing, C1
Eckersdorff, M1
Alt, FW1
Xu, Y1
Cook, CE1
Verhoeven, WM1
Van Ravenswaaij-Arts, CM1
De Leeuw, N1
Fekkes, D1
Van der Heijden, FM1
Egger, JI1
Tuinier, S1
Iida, S1
Seto, M1
Yamamoto, K1
Komatsu, H1
Tojo, A1
Asano, S1
Kamada, N1
Ariyoshi, Y1
Takahashi, T1
Ueda, R1
Morrissey, J1
Tkachuk, DC1
Milatovich, A1
Francke, U1
Link, M1
Cleary, ML2
Morrissey, JJ1
Raney, S1
Gripp, KW1
Stolle, CA1
McDonald-McGinn, DM1
Markowitz, RI1
Bartlett, SP1
Katowitz, JA1
Muenke, M1
Zackai, EH1
Liao, ZY1
Tang, YH1
Xu, MH1
Feng, YM1
Zhu, SQ1
Amson, RB1
Marcelle, C1
Telerman, A1

Reviews

1 review available for serine and Chromosomal Translocation

ArticleYear
The response of human natural killer cells to interleukin-2.
    Journal of endocrinological investigation, 2004, Volume: 27, Issue:6 Suppl

    Topics: Animals; Cell Nucleus; Cyclic AMP Response Element-Binding Protein; Humans; Interleukin-2; Isoenzyme

2004

Other Studies

19 other studies available for serine and Chromosomal Translocation

ArticleYear
Association between chromosome 22q11.2 translocation and male oligozoospermia.
    Medicine, 2022, Sep-30, Volume: 101, Issue:39

    Topics: Chromosome Aberrations; Chromosomes; Humans; Infertility, Male; Male; Oligospermia; Protein Serine-T

2022
Crosstalk between 14-3-3θ and AF4 enhances MLL-AF4 activity and promotes leukemia cell proliferation.
    Cellular oncology (Dordrecht), 2019, Volume: 42, Issue:6

    Topics: 14-3-3 Proteins; Apoptosis; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cell Survival; DNA-B

2019
[Screening hv-S/TPK from TAC library of a Triticum aestivum-Haynaldia villosa translocation line].
    Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 2008, Volume: 24, Issue:8

    Topics: Base Sequence; Chromosomes, Artificial; Cloning, Molecular; Genomic Library; Molecular Sequence Data

2008
Suppression of nonhomologous end joining repair by overexpression of HMGA2.
    Cancer research, 2009, Jul-15, Volume: 69, Issue:14

    Topics: Animals; Antigens, Nuclear; Blotting, Western; Cell Line; Cell Line, Tumor; CHO Cells; Cricetinae; C

2009
Phosphorylation of serine 205 by the protein kinase CK2 persists on Pax3-FOXO1, but not Pax3, throughout early myogenic differentiation.
    Biochemistry, 2009, Dec-15, Volume: 48, Issue:49

    Topics: Animals; Casein Kinase II; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cells, Cultur

2009
Proline-rich domain plays a crucial role in extracellular stimuli-responsive translocation of a Cdc42 guanine nucleotide exchange factor, FGD1.
    Biological & pharmaceutical bulletin, 2010, Volume: 33, Issue:1

    Topics: Biological Transport; Cell Membrane; Epidermal Growth Factor; Guanine Nucleotide Exchange Factors; H

2010
A novel balanced chromosomal translocation found in subjects with schizophrenia and schizotypal personality disorder: altered l-serine level associated with disruption of PSAT1 gene expression.
    Neuroscience research, 2011, Volume: 69, Issue:2

    Topics: Age of Onset; Animals; Astrocytes; Blotting, Western; Chromatography, High Pressure Liquid; Chromoso

2011
LEDGF activation of PKC gamma and gap junction disassembly in lens epithelial cells.
    Experimental eye research, 2003, Volume: 76, Issue:5

    Topics: Animals; Connexin 43; Enzyme Activation; Epithelial Cells; Gap Junctions; Intercellular Signaling Pe

2003
Activation of formyl peptide receptor-like 1 by WKYMVm induces serine phosphorylation of STAT3, which inhibits its tyrosine phosphorylation and nuclear translocation induced by hydrogen peroxide.
    Life sciences, 2004, Sep-17, Volume: 75, Issue:18

    Topics: Biotransformation; Cell Line; Cell Nucleus; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Ge

2004
The nuclear receptor co-repressor (N-CoR) utilizes repression domains I and III for interaction and co-repression with ETO.
    The Journal of biological chemistry, 2004, Nov-19, Volume: 279, Issue:47

    Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Binding Sites; Blotting, Western; Cell Line; Cystei

2004
Functional interaction of H2AX, NBS1, and p53 in ATM-dependent DNA damage responses and tumor suppression.
    Molecular and cellular biology, 2005, Volume: 25, Issue:2

    Topics: Animals; Ataxia Telangiectasia Mutated Proteins; Cell Cycle; Cell Cycle Proteins; Cells, Cultured; C

2005
The complete mitochondrial genome of the stomatopod crustacean Squilla mantis.
    BMC genomics, 2005, Aug-09, Volume: 6

    Topics: Animals; Base Composition; Base Sequence; Codon; Computational Biology; Crustacea; DNA Primers; DNA,

2005
Disturbed serine metabolism and psychosis in a patient with a de novo translocation (2;10)(p23;q22.1).
    Genetic counseling (Geneva, Switzerland), 2006, Volume: 17, Issue:4

    Topics: Adult; Chromosomes, Human, Pair 10; Chromosomes, Human, Pair 2; DiGeorge Syndrome; Female; Humans; H

2006
MLLT3 gene on 9p22 involved in t(9;11) leukemia encodes a serine/proline rich protein homologous to MLLT1 on 19p13.
    Oncogene, 1993, Volume: 8, Issue:11

    Topics: Adult; Amino Acid Sequence; Base Sequence; Cell Line; Chromosomes, Human, Pair 11; Chromosomes, Huma

1993
A serine/proline-rich protein is fused to HRX in t(4;11) acute leukemias.
    Blood, 1993, Mar-01, Volume: 81, Issue:5

    Topics: Amino Acid Sequence; Base Sequence; Child; Chromosome Mapping; Chromosomes, Human, Pair 11; Chromoso

1993
The FEL (AF-4) protein donates transcriptional activation sequences to Hrx-Fel fusion proteins in leukemias containing T(4;11)(Q21;Q23) chromosomal translocations.
    Leukemia research, 1997, Volume: 21, Issue:10

    Topics: Adenoviridae; Adenovirus E1B Proteins; Amino Acid Sequence; Animals; Binding Sites; Chromosomes, Hum

1997
Phenotype of the fibroblast growth factor receptor 2 Ser351Cys mutation: Pfeiffer syndrome type III.
    American journal of medical genetics, 1998, Jul-24, Volume: 78, Issue:4

    Topics: Abnormalities, Multiple; Acrocephalosyndactylia; Amino Acid Substitution; Cysteine; Elbow; Eye Abnor

1998
B9-serine residue is crucial for insulin actions in glucose metabolism.
    Acta pharmacologica Sinica, 2001, Volume: 22, Issue:10

    Topics: Adipocytes; Animals; Binding Sites; Cell Separation; Epididymis; Glucose; Insulin; Male; Monosacchar

2001
Identification of a 130 Kda bcr related gene product.
    Oncogene, 1989, Volume: 4, Issue:2

    Topics: Amino Acids; Leukemia; Phosphorylation; Protein Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Pr

1989