Page last updated: 2024-11-08

serine and Chondrosarcoma

serine has been researched along with Chondrosarcoma in 12 studies

Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.

Chondrosarcoma: A slowly growing malignant neoplasm derived from cartilage cells, occurring most frequently in pelvic bones or near the ends of long bones, in middle-aged and old people. Most chondrosarcomas arise de novo, but some may develop in a preexisting benign cartilaginous lesion or in patients with ENCHONDROMATOSIS. (Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
"Chondrocytes from the Swarm rat chondrosarcoma were pulse-labeled with [3H]serine for 30 min and chased, in the presence of cycloheximide, for times up to 300 min."3.67Localization of proteoglycan core protein in subcellular fractions isolated from rat chondrosarcoma chondrocytes. ( Fellini, SA; Hascall, VC; Kimura, JH, 1984)
"Rat chondrosarcoma chondrocytes were labeled with [3H]serine or [3H]mannose as a precursor."3.67Xylosyl transfer to the core protein precursor of the rat chondrosarcoma proteoglycan. ( Hascall, VC; Kimura, JH; Lohmander, LS; Shinomura, T, 1989)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19909 (75.00)18.7374
1990's1 (8.33)18.2507
2000's1 (8.33)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kamemura, N1
Murakami, S1
Komatsu, H1
Sawanoi, M1
Miyamoto, K1
Ishidoh, K1
Kishimoto, K1
Tsuji, A1
Yuasa, K1
ANDERSON, B1
HOFFMAN, P1
MEYER, K1
Fellini, SA2
Hascall, VC6
Kimura, JH6
Stevens, RL1
Nissley, SP1
Rechler, MM1
Caplan, AI1
Caputo, CB1
Mitchell, D1
Hardingham, T1
Mason, RM1
d'Arville, C1
Huang, W1
Zhou, X1
Lefebvre, V1
de Crombrugghe, B1
Kearns, AE1
Campbell, SC1
Westley, J1
Schwartz, NB1
Lohmander, LS1
Shinomura, T1
Lucas, PA1
Dziewiatkowski, DD1

Other Studies

12 other studies available for serine and Chondrosarcoma

ArticleYear
Type II cGMP-dependent protein kinase negatively regulates fibroblast growth factor signaling by phosphorylating Raf-1 at serine 43 in rat chondrosarcoma cells.
    Biochemical and biophysical research communications, 2017, 01-29, Volume: 483, Issue:1

    Topics: Amino Acid Substitution; Animals; Binding Sites; Chondrocytes; Chondrosarcoma; Cyclic GMP; Cyclic GM

2017
THE O-SERINE LINKAGE IN PEPTIDES OF CHONDROITIN 4- OR 6-SULFATE.
    The Journal of biological chemistry, 1965, Volume: 240

    Topics: Amino Acids; Animals; Cattle; Chondroitin; Chondrosarcoma; Chromatography; Histocytochemistry; Papai

1965
Localization of proteoglycan core protein in subcellular fractions isolated from rat chondrosarcoma chondrocytes.
    The Journal of biological chemistry, 1984, Apr-10, Volume: 259, Issue:7

    Topics: Animals; Cartilage; Cell Fractionation; Cell Line; Centrifugation, Density Gradient; Chondrosarcoma;

1984
Effects of insulin and multiplication-stimulating activity on proteoglycan biosynthesis in chondrocytes from the Swarm rat chondrosarcoma.
    The Journal of biological chemistry, 1981, Feb-25, Volume: 256, Issue:4

    Topics: Animals; Cartilage; Cell Line; Chondrosarcoma; DNA; DNA, Neoplasm; Glucosamine; Insulin; Insulin-Lik

1981
The effect of cycloheximide on synthesis of proteoglycans by cultured chondrocytes from the Swarm rat chondrosarcoma.
    The Journal of biological chemistry, 1981, May-10, Volume: 256, Issue:9

    Topics: Animals; Cartilage; Cells, Cultured; Chondrosarcoma; Cycloheximide; Kinetics; Methionine; Neoplasms,

1981
Polydispersity of proteoglycans synthesized by chondrocytes from the Swarm rat chondrosarcoma.
    The Journal of biological chemistry, 1981, Aug-10, Volume: 256, Issue:15

    Topics: Animals; Cartilage; Cells, Cultured; Chondrosarcoma; Glucosamine; Methionine; Molecular Weight; Prot

1981
The effects of cycloheximide on the biosynthesis and secretion of proteoglycans by chondrocytes in culture.
    The Biochemical journal, 1981, May-15, Volume: 196, Issue:2

    Topics: Animals; Cartilage; Cells, Cultured; Chemical Phenomena; Chemistry; Chondrosarcoma; Cycloheximide; K

1981
Absence of covalently linked core protein from newly synthesized hyaluronate.
    The Biochemical journal, 1982, Dec-01, Volume: 207, Issue:3

    Topics: Animals; Betaine; Cells, Cultured; Centrifugation, Density Gradient; Chondrosarcoma; Chromatography,

1982
Phosphorylation of SOX9 by cyclic AMP-dependent protein kinase A enhances SOX9's ability to transactivate a Col2a1 chondrocyte-specific enhancer.
    Molecular and cellular biology, 2000, Volume: 20, Issue:11

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amino Acid Sequence; Animals; Binding Sites; Chondrocytes; C

2000
Initiation of chondroitin sulfate biosynthesis: a kinetic analysis of UDP-D-xylose: core protein beta-D-xylosyltransferase.
    Biochemistry, 1991, Jul-30, Volume: 30, Issue:30

    Topics: Amino Acid Sequence; Animals; Carbohydrate Sequence; Chondroitin Sulfate Proteoglycans; Chondrosarco

1991
Xylosyl transfer to the core protein precursor of the rat chondrosarcoma proteoglycan.
    The Journal of biological chemistry, 1989, Nov-05, Volume: 264, Issue:31

    Topics: Acetylgalactosamine; Aggrecans; Alanine; Animals; Chondrosarcoma; Chromatography, High Pressure Liqu

1989
Feedback control of selected biosynthetic activities of chondrocytes in culture.
    Connective tissue research, 1987, Volume: 16, Issue:4

    Topics: Animals; Cartilage; Cell Count; Chickens; Chondrosarcoma; Collagen; Comb and Wattles; Feedback; Huma

1987