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serine and Cell Transformation, Viral

serine has been researched along with Cell Transformation, Viral in 38 studies

Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.

Cell Transformation, Viral: An inheritable change in cells manifested by changes in cell division and growth and alterations in cell surface properties. It is induced by infection with a transforming virus.

Research Excerpts

ExcerptRelevanceReference
" We aimed to explore the role of histone H3 phosphorylation at serine10 (p-H3Ser10) in Epstein-Barr virus (EBV) latent membrane protein-1 (LMP1)-induced carcinogenesis of nasopharyngeal carcinoma (NPC)."7.79Increased phosphorylation of histone H3 at serine 10 is involved in Epstein-Barr virus latent membrane protein-1-induced carcinogenesis of nasopharyngeal carcinoma. ( Dong, Z; He, Z; Huang, G; Li, B; Li, R; Wang, J; Zhang, X, 2013)
" We aimed to explore the role of histone H3 phosphorylation at serine10 (p-H3Ser10) in Epstein-Barr virus (EBV) latent membrane protein-1 (LMP1)-induced carcinogenesis of nasopharyngeal carcinoma (NPC)."3.79Increased phosphorylation of histone H3 at serine 10 is involved in Epstein-Barr virus latent membrane protein-1-induced carcinogenesis of nasopharyngeal carcinoma. ( Dong, Z; He, Z; Huang, G; Li, B; Li, R; Wang, J; Zhang, X, 2013)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199017 (44.74)18.7374
1990's12 (31.58)18.2507
2000's7 (18.42)29.6817
2010's2 (5.26)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wang, LW1
Shen, H1
Nobre, L1
Ersing, I1
Paulo, JA1
Trudeau, S1
Wang, Z1
Smith, NA1
Ma, Y1
Reinstadler, B1
Nomburg, J1
Sommermann, T1
Cahir-McFarland, E1
Gygi, SP1
Mootha, VK1
Weekes, MP1
Gewurz, BE1
Li, B1
Huang, G1
Zhang, X1
Li, R1
Wang, J1
Dong, Z1
He, Z1
Kato, K1
Yokoyama, A1
Tohya, Y1
Akashi, H1
Nishiyama, Y1
Kawaguchi, Y1
Starczynowski, DT1
Reynolds, JG1
Gilmore, TD2
Higashi, T1
Tsukada, J1
Yoshida, Y1
Mizobe, T1
Mouri, F1
Minami, Y1
Morimoto, H1
Tanaka, Y1
Kim, YM1
Cao, D1
Reed, W1
Wu, W1
Jaspers, I1
Tal, T1
Bromberg, PA1
Samet, JM1
Blomberg, J1
Van de Ven, WJ1
Reynolds, FH1
Nalewaik, RP1
Stephenson, JR1
Sen, A1
Decker, S1
Radke, K1
Martin, GS1
Papkoff, J1
Verma, IM1
Hunter, T2
Piedimonte, G1
Borghetti, AF1
Guidotti, GG1
Cross, FR1
Hanafusa, H1
Cobb, MH1
Rosen, OM1
Müller, E1
Scheidtmann, KH1
Gerlitz, B1
Hassell, T1
Vlahos, CJ1
Parkinson, JF1
Bang, NU1
Grinnell, BW1
Carpenter, CL1
Auger, KR1
Duckworth, BC1
Hou, WM1
Schaffhausen, B1
Cantley, LC1
Moorthy, RK1
Thorley-Lawson, DA1
Sparkowski, J1
Mense, M1
Anders, J1
Schlegel, R1
Whalen, SG1
Marcellus, RC1
Barbeau, D1
Branton, PE1
Schouten, GJ1
Vertegaal, AC1
Whiteside, ST1
Israël, A1
Toebes, M1
Dorsman, JC1
van der Eb, AJ1
Zantema, A1
Willems, L1
Grimonpont, C1
Kerkhofs, P1
Capiau, C1
Gheysen, D1
Conrath, K1
Roussef, R1
Mamoun, R1
Portetelle, D1
Burny, A1
Adam, E1
Lefèbvre, L1
Twizere, JC1
Heremans, H1
Kettmann, R1
Pise-Masison, CA1
Radonovich, M1
Sakaguchi, K1
Appella, E1
Brady, JN1
Longnecker, R1
Kirken, RA1
Erwin, RA1
Wang, L1
Wang, Y1
Rui, H1
Farrar, WL1
Mazurek, S1
Zwerschke, W1
Jansen-Dürr, P1
Eigenbrodt, E1
Anderson, R1
Wu, H1
Reynolds, AB1
Kanner, SB1
Vines, RR1
Parsons, JT1
Li, X1
Rhode, SL1
Storey, A1
Almond, N1
Osborn, K1
Crawford, L1
Matthews, JT1
Benjamin, TL1
Martin-Perez, J1
Bar-Zvi, D1
Branton, D1
Erikson, RL1
Tsukamoto, AS1
Ponticelli, A1
Berk, AJ1
Gaynor, RB1
Isacke, CM1
Trowbridge, IS1
Giese, NA1
Robbins, KC1
Aaronson, SA1
Wang, LH1
Lin, B1
Jong, SM1
Dixon, D1
Ellis, L1
Roth, RA1
Rutter, WJ1
Maller, JL1
Foulkes, JG1
Erikson, E1
Baltimore, D1
Schughart, K1
Bause, E1
Esche, H1

Reviews

2 reviews available for serine and Cell Transformation, Viral

ArticleYear
The insulin receptor and tyrosine protein kinase activity.
    Biochimica et biophysica acta, 1984, Volume: 738, Issue:1-2

    Topics: Adenosine Triphosphate; Animals; Avian Sarcoma Viruses; Cations, Divalent; Cell Membrane; Cell Trans

1984
Epstein-Barr virus latency: LMP2, a regulator or means for Epstein-Barr virus persistence?
    Advances in cancer research, 2000, Volume: 79

    Topics: Adolescent; Amino Acid Motifs; Amino Acid Sequence; Animals; B-Lymphocytes; Cell Line, Transformed;

2000

Other Studies

36 other studies available for serine and Cell Transformation, Viral

ArticleYear
Epstein-Barr-Virus-Induced One-Carbon Metabolism Drives B Cell Transformation.
    Cell metabolism, 2019, 09-03, Volume: 30, Issue:3

    Topics: Aminohydrolases; B-Lymphocytes; Cell Transformation, Viral; Epstein-Barr Virus Infections; Epstein-B

2019
Increased phosphorylation of histone H3 at serine 10 is involved in Epstein-Barr virus latent membrane protein-1-induced carcinogenesis of nasopharyngeal carcinoma.
    BMC cancer, 2013, Mar-18, Volume: 13

    Topics: Adult; Carcinoma; Cell Line; Cell Transformation, Viral; Female; Gene Expression; Histones; Humans;

2013
Identification of protein kinases responsible for phosphorylation of Epstein-Barr virus nuclear antigen leader protein at serine-35, which regulates its coactivator function.
    The Journal of general virology, 2003, Volume: 84, Issue:Pt 12

    Topics: Alanine; Amino Acid Substitution; Animals; CDC2 Protein Kinase; Cell Line; Cell Transformation, Vira

2003
Mutations of tumor necrosis factor alpha-responsive serine residues within the C-terminal transactivation domain of human transcription factor REL enhance its in vitro transforming ability.
    Oncogene, 2005, Nov-10, Volume: 24, Issue:49

    Topics: Animals; Blotting, Western; Cell Transformation, Viral; Cells, Cultured; Chickens; Electrophoretic M

2005
Constitutive tyrosine and serine phosphorylation of STAT4 in T-cells transformed with HTLV-I.
    Genes to cells : devoted to molecular & cellular mechanisms, 2005, Volume: 10, Issue:12

    Topics: Blotting, Western; Cell Line; Cell Transformation, Viral; Electrophoretic Mobility Shift Assay; Gene

2005
Zn2+-induced NF-kappaB-dependent transcriptional activity involves site-specific p65/RelA phosphorylation.
    Cellular signalling, 2007, Volume: 19, Issue:3

    Topics: Cell Line, Transformed; Cell Transformation, Viral; Clone Cells; Humans; NF-kappa B; Phosphorylation

2007
Snyder-Theilen feline sarcoma virus P85 contains a single phosphotyrosine acceptor site recognized by its associated protein kinase.
    Journal of virology, 1981, Volume: 38, Issue:3

    Topics: Binding Sites; Cell Transformation, Neoplastic; Cell Transformation, Viral; Phosphorylation; Phospho

1981
Purified low-molecular-weight protein kinase from murine sarcoma virus particles catalyzes tyrosine phosphorylation endogenously but phosphorylates cellular proteins at serine.
    Journal of virology, 1981, Volume: 39, Issue:2

    Topics: Adenosine Triphosphate; Animals; Cell Line; Cell Transformation, Viral; Magnesium; Mice; Phosphoryla

1981
Phosphorylation of ribosomal protein S6 in avian sarcoma virus-transformed chicken embryo fibroblasts.
    Proceedings of the National Academy of Sciences of the United States of America, 1981, Volume: 78, Issue:7

    Topics: Alpharetrovirus; Animals; Cell Transformation, Viral; Culture Media; Growth Substances; Molecular We

1981
Tyrosine phosphorylation of a 50K cellular polypeptide associated with the Rous sarcoma virus transforming protein pp60src.
    Molecular and cellular biology, 1982, Volume: 2, Issue:2

    Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Viral; Cells, Cultured; Chick Embryo; Defective

1982
Detection of a transforming gene product in cells transformed by Moloney murine sarcoma virus.
    Cell, 1982, Volume: 29, Issue:2

    Topics: Animals; Cell Transformation, Viral; Cells, Cultured; Fibroblasts; Mice; Moloney murine leukemia vir

1982
Effect of cell density on growth rate and amino acid transport in simian virus 40-transformed 3T3 cells.
    Cancer research, 1982, Volume: 42, Issue:11

    Topics: Animals; Biological Transport; Cell Division; Cell Transformation, Viral; Cells, Cultured; Kinetics;

1982
Local mutagenesis of Rous sarcoma virus: the major sites of tyrosine and serine phosphorylation of pp60src are dispensable for transformation.
    Cell, 1983, Volume: 34, Issue:2

    Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Viral; Chick Embryo; Mutation; Oncogene Protein

1983
Purification and characterization of a protein kinase which is activated by SV40 large T-antigen and phosphorylates the tumor suppressor protein p53.
    Oncogene, 1995, Mar-16, Volume: 10, Issue:6

    Topics: Amino Acid Sequence; Animals; Antigens, Polyomavirus Transforming; Cell Cycle; Cell Transformation,

1995
Identification of the predominant glycosaminoglycan-attachment site in soluble recombinant human thrombomodulin: potential regulation of functionality by glycosyltransferase competition for serine474.
    The Biochemical journal, 1993, Oct-01, Volume: 295 ( Pt 1)

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Cell Transformation, Viral; Cells, Cultu

1993
A tightly associated serine/threonine protein kinase regulates phosphoinositide 3-kinase activity.
    Molecular and cellular biology, 1993, Volume: 13, Issue:3

    Topics: Animals; Antigens, Polyomavirus Transforming; Cell Transformation, Viral; Gene Expression Regulation

1993
Biochemical, genetic, and functional analyses of the phosphorylation sites on the Epstein-Barr virus-encoded oncogenic latent membrane protein LMP-1.
    Journal of virology, 1993, Volume: 67, Issue:5

    Topics: Amino Acid Sequence; Animals; Cell Transformation, Viral; Chromobox Protein Homolog 5; DNA Mutationa

1993
E5 oncoprotein transmembrane mutants dissociate fibroblast transforming activity from 16-kilodalton protein binding and platelet-derived growth factor receptor binding and phosphorylation.
    Journal of virology, 1996, Volume: 70, Issue:4

    Topics: 3T3 Cells; Adenosine Triphosphatases; Amino Acid Sequence; Animals; Base Sequence; Cell Transformati

1996
Importance of the Ser-132 phosphorylation site in cell transformation and apoptosis induced by the adenovirus type 5 E1A protein.
    Journal of virology, 1996, Volume: 70, Issue:8

    Topics: Adenoviridae; Adenovirus E1A Proteins; Amino Acid Sequence; Apoptosis; Cell Line, Transformed; Cell

1996
IkappaB alpha is a target for the mitogen-activated 90 kDa ribosomal S6 kinase.
    The EMBO journal, 1997, Jun-02, Volume: 16, Issue:11

    Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Transformation, Neoplastic; Cell Transfo

1997
Phosphorylation of bovine leukemia virus Tax protein is required for in vitro transformation but not for transactivation.
    Oncogene, 1998, Apr-30, Volume: 16, Issue:17

    Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cattle; CDC2 Protein Kinase; Cell Line; Cell

1998
Phosphorylation of p53: a novel pathway for p53 inactivation in human T-cell lymphotropic virus type 1-transformed cells.
    Journal of virology, 1998, Volume: 72, Issue:8

    Topics: Binding Sites; Cell Line, Transformed; Cell Transformation, Viral; Human T-lymphotropic virus 1; Hum

1998
Functional uncoupling of the Janus kinase 3-Stat5 pathway in malignant growth of human T cell leukemia virus type 1-transformed human T cells.
    Journal of immunology (Baltimore, Md. : 1950), 2000, Nov-01, Volume: 165, Issue:9

    Topics: Cell Line, Transformed; Cell Transformation, Neoplastic; Cell Transformation, Viral; DNA-Binding Pro

2000
Effects of the human papilloma virus HPV-16 E7 oncoprotein on glycolysis and glutaminolysis: role of pyruvate kinase type M2 and the glycolytic-enzyme complex.
    The Biochemical journal, 2001, May-15, Volume: 356, Issue:Pt 1

    Topics: 3T3 Cells; Animals; Cell Transformation, Viral; Glutamine; Glycolysis; Isoenzymes; Lactates; Mice; M

2001
Regulation of glycolipid biosynthesis: effects of virus infection and drug-induced translational inhibition on glycolipid metabolism.
    Biochemistry, 1979, May-29, Volume: 18, Issue:11

    Topics: Cell Transformation, Viral; Cycloheximide; Galactose; Galactosyltransferases; Glucosyltransferases;

1979
Identification and characterization of a novel cytoskeleton-associated pp60src substrate.
    Molecular and cellular biology, 1991, Volume: 11, Issue:10

    Topics: Amino Acid Sequence; Animals; Avian Proteins; Base Sequence; Blotting, Northern; Blotting, Western;

1991
Mutation of lysine 405 to serine in the parvovirus H-1 NS1 abolishes its functions for viral DNA replication, late promoter trans activation, and cytotoxicity.
    Journal of virology, 1990, Volume: 64, Issue:10

    Topics: Capsid; Cell Line; Cell Transformation, Viral; DNA Replication; DNA, Viral; Humans; Lysine; Mutation

1990
Mutations of the human papillomavirus type 16 E7 gene that affect transformation, transactivation and phosphorylation by the E7 protein.
    The Journal of general virology, 1990, Volume: 71 ( Pt 4)

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cysteine; DNA Mutat

1990
12-O-tetradecanoylphorbol-13-acetate stimulates phosphorylation of the 58,000-Mr form of polyomavirus middle T antigen in vivo: implications for a possible role of protein kinase C in middle T function.
    Journal of virology, 1986, Volume: 58, Issue:2

    Topics: Animals; Antigens, Polyomavirus Transforming; Antigens, Viral, Tumor; Cell Line; Cell Transformation

1986
Transformation by Rous sarcoma virus induces clathrin heavy chain phosphorylation.
    The Journal of cell biology, 1989, Volume: 109, Issue:2

    Topics: Animals; Avian Sarcoma Viruses; Cell Line, Transformed; Cell Transformation, Viral; Cells, Cultured;

1989
Genetic mapping of a major site of phosphorylation in adenovirus type 2 E1A proteins.
    Journal of virology, 1986, Volume: 59, Issue:1

    Topics: Adenovirus Early Proteins; Adenoviruses, Human; Alanine; Animals; Cell Line; Cell Transformation, Vi

1986
Modulation of p36 phosphorylation in human cells: studies using anti-p36 monoclonal antibodies.
    Molecular and cellular biology, 1986, Volume: 6, Issue:7

    Topics: Annexins; Antibodies, Monoclonal; Cell Transformation, Viral; Epidermal Growth Factor; Humans; Membr

1986
The role of individual cysteine residues in the structure and function of the v-sis gene product.
    Science (New York, N.Y.), 1987, Jun-05, Volume: 236, Issue:4806

    Topics: Antigens, Polyomavirus Transforming; Antigens, Viral, Tumor; Cell Transformation, Viral; Cross React

1987
Activation of transforming potential of the human insulin receptor gene.
    Proceedings of the National Academy of Sciences of the United States of America, 1987, Volume: 84, Issue:16

    Topics: Animals; Avian Sarcoma Viruses; Base Sequence; Cell Transformation, Viral; Chick Embryo; Cytopathoge

1987
Phosphorylation of ribosomal protein S6 on serine after microinjection of the Abelson murine leukemia virus tyrosine-specific protein kinase into Xenopus oocytes.
    Proceedings of the National Academy of Sciences of the United States of America, 1985, Volume: 82, Issue:2

    Topics: Abelson murine leukemia virus; Amino Acids; Animals; Cell Line; Cell Transformation, Viral; Female;

1985
Structure and expression of adenovirus type 12 E1B 58K protein in infected and transformed cells: studies using antibodies directed against a synthetic peptide.
    Virus research, 1985, Volume: 3, Issue:1

    Topics: Adenoviruses, Human; Amino Acid Sequence; Animals; Antigens, Viral, Tumor; Cell Line; Cell Transform

1985