serine has been researched along with Cardiomyopathies in 14 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Cardiomyopathies: A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "We hypothesized that Chikusetsusaponin IVa (CS), a major component of Saponins from Panaxjaponicus, may improve isoprenaline induced myocardial fibrosis via AMPK/mTOR/ULK1 mediated autophagy METHODS: Continuous subcutaneous injection of isoproterenol for 21 days was used to induce myocardial fibrosis in mice and high and low doses (15 mg/kg and 5 mg/kg) of CS was administered by oral gavage to observe the efficacy." | 7.91 | Chikusetsu saponin IVa attenuates isoprenaline-induced myocardial fibrosis in mice through activation autophagy mediated by AMPK/mTOR/ULK1 signaling. ( He, Y; Liu, C; Liu, X; Wang, J; Wang, L; Wang, T; Wu, X; Yuan, D; Zhang, C; Zheng, J; Zhou, Z, 2019) |
| "We hypothesized that Chikusetsusaponin IVa (CS), a major component of Saponins from Panaxjaponicus, may improve isoprenaline induced myocardial fibrosis via AMPK/mTOR/ULK1 mediated autophagy METHODS: Continuous subcutaneous injection of isoproterenol for 21 days was used to induce myocardial fibrosis in mice and high and low doses (15 mg/kg and 5 mg/kg) of CS was administered by oral gavage to observe the efficacy." | 3.91 | Chikusetsu saponin IVa attenuates isoprenaline-induced myocardial fibrosis in mice through activation autophagy mediated by AMPK/mTOR/ULK1 signaling. ( He, Y; Liu, C; Liu, X; Wang, J; Wang, L; Wang, T; Wu, X; Yuan, D; Zhang, C; Zheng, J; Zhou, Z, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 5 (35.71) | 24.3611 |
| 2020's | 2 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Zhu, H | 1 |
| Dai, Z | 1 |
| Liu, X | 2 |
| Zhou, H | 1 |
| Wang, Y | 1 |
| Wang, Q | 1 |
| Zhan, S | 1 |
| Han, F | 1 |
| Liu, Y | 1 |
| Wu, H | 1 |
| Huang, Z | 1 |
| Wang, L | 1 |
| Yuan, D | 1 |
| Zheng, J | 1 |
| Wu, X | 1 |
| Wang, J | 1 |
| He, Y | 1 |
| Zhang, C | 1 |
| Liu, C | 1 |
| Wang, T | 1 |
| Zhou, Z | 1 |
| Liu, B | 1 |
| Ho, HT | 1 |
| Velez-Cortes, F | 1 |
| Lou, Q | 1 |
| Valdivia, CR | 1 |
| Knollmann, BC | 1 |
| Valdivia, HH | 1 |
| Gyorke, S | 1 |
| Backx, PH | 1 |
| Schaeffer, PJ | 1 |
| Desantiago, J | 1 |
| Yang, J | 1 |
| Flagg, TP | 1 |
| Kovacs, A | 1 |
| Weinheimer, CJ | 1 |
| Courtois, M | 1 |
| Leone, TC | 1 |
| Nichols, CG | 1 |
| Bers, DM | 1 |
| Kelly, DP | 1 |
| Kobayashi, T | 2 |
| Aoki, Y | 1 |
| Niihori, T | 1 |
| Cavé, H | 1 |
| Verloes, A | 1 |
| Okamoto, N | 1 |
| Kawame, H | 1 |
| Fujiwara, I | 1 |
| Takada, F | 1 |
| Ohata, T | 1 |
| Sakazume, S | 1 |
| Ando, T | 1 |
| Nakagawa, N | 1 |
| Lapunzina, P | 1 |
| Meneses, AG | 1 |
| Gillessen-Kaesbach, G | 1 |
| Wieczorek, D | 1 |
| Kurosawa, K | 1 |
| Mizuno, S | 1 |
| Ohashi, H | 1 |
| David, A | 1 |
| Philip, N | 1 |
| Guliyeva, A | 1 |
| Narumi, Y | 1 |
| Kure, S | 1 |
| Tsuchiya, S | 1 |
| Matsubara, Y | 1 |
| Chalabreysse, L | 1 |
| Senni, F | 1 |
| Bruyère, P | 1 |
| Aime, B | 1 |
| Ollagnier, C | 1 |
| Bozio, A | 1 |
| Bouvagnet, P | 1 |
| Lobrinus, JA | 1 |
| Schorderet, DF | 1 |
| Payot, M | 1 |
| Jeanrenaud, X | 1 |
| Bottani, A | 1 |
| Superti-Furga, A | 1 |
| Schlaepfer, J | 1 |
| Fromer, M | 1 |
| Jeannet, PY | 1 |
| Biesiadecki, BJ | 1 |
| Walker, JS | 1 |
| Solaro, RJ | 1 |
| de Tombe, PP | 1 |
| Malhotra, A | 1 |
| Kang, BP | 1 |
| Vashistha, H | 1 |
| Yadav, VS | 1 |
| Meggs, LG | 1 |
| Uemichi, T | 1 |
| Gertz, MA | 1 |
| Benson, MD | 1 |
| Hahner, A | 1 |
| Erdmann, J | 1 |
| Kallisch, H | 1 |
| Fleck, E | 1 |
| Regitz-Zagrosek, V | 1 |
| Nishi, H | 1 |
| Kimura, A | 1 |
| Harada, H | 1 |
| Hayashi, Y | 1 |
| Nakamura, M | 1 |
| Sasazuki, T | 1 |
1 review available for serine and Cardiomyopathies
| Article | Year |
|---|---|
The Possible Mechanism of Physiological Adaptation to the Low-Se Diet and Its Health Risk in the Traditional Endemic Areas of Keshan Diseases.
Topics: Adaptation, Physiological; Animals; Cardiomyopathies; Cysteine; Diet; Enterovirus Infections; Seleni | 2022 |
13 other studies available for serine and Cardiomyopathies
| Article | Year |
|---|---|
Serine/threonine kinase 3 promotes oxidative stress and mitochondrial damage in septic cardiomyopathy through inducing Kelch-like ECH-associated protein 1 phosphorylation and nuclear factor erythroid 2-related factor 2 degradation.
Topics: Animals; Antioxidants; Cardiomyopathies; Kelch-Like ECH-Associated Protein 1; Lipopolysaccharides; M | 2023 |
Chikusetsu saponin IVa attenuates isoprenaline-induced myocardial fibrosis in mice through activation autophagy mediated by AMPK/mTOR/ULK1 signaling.
Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Autophagy-Related Protein-1 Homolog; Cardiomyopat | 2019 |
Genetic ablation of ryanodine receptor 2 phosphorylation at Ser-2808 aggravates Ca(2+)-dependent cardiomyopathy by exacerbating diastolic Ca2+ release.
Topics: Animals; Calcium; Cardiomyopathies; Female; Male; Mice; Mice, Knockout; Mice, Transgenic; Phosphoryl | 2014 |
Complexity, confusion and controversy continue complicating the contribution of RyR2 channel phosphorylation to heart function.
Topics: Animals; Calcium; Cardiomyopathies; Female; Male; Ryanodine Receptor Calcium Release Channel; Serine | 2014 |
Impaired contractile function and calcium handling in hearts of cardiac-specific calcineurin b1-deficient mice.
Topics: Aging; Animals; Calcineurin; Calcium Signaling; Calcium-Binding Proteins; Cardiomyopathies; Cardioto | 2009 |
Molecular and clinical analysis of RAF1 in Noonan syndrome and related disorders: dephosphorylation of serine 259 as the essential mechanism for mutant activation.
Topics: 14-3-3 Proteins; Animals; Cardiomyopathies; Facies; Humans; Mice; Models, Genetic; Mutation; NIH 3T3 | 2010 |
A new hypo/oligodontia syndrome: Carvajal/Naxos syndrome secondary to desmoplakin-dominant mutations.
Topics: Adolescent; Amino Acid Sequence; Anodontia; Arrhythmogenic Right Ventricular Dysplasia; Bicuspid; Ca | 2011 |
Morphological, clinical and genetic aspects in a family with a novel LAMP-2 gene mutation (Danon disease).
Topics: Adolescent; Adult; Antigens, CD; Biopsy; Cardiomyopathies; Child; DNA Mutational Analysis; Family He | 2005 |
The troponin C G159D mutation blunts myofilament desensitization induced by troponin I Ser23/24 phosphorylation.
Topics: Actin Cytoskeleton; Calcium; Cardiomyopathies; Cyclic AMP-Dependent Protein Kinases; Humans; Mutatio | 2007 |
Overexpression of Gsalpha compensates for myocyte loss in diabetic cardiomyopathy.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Calcium-Binding Prote | 2008 |
A new transthyretin variant (Ser 24) associated with familial amyloid polyneuropathy.
Topics: Aged; Amyloid Neuropathies; Cardiomyopathies; Codon; Cytosine; DNA; Exons; Family Health; Female; Ge | 1995 |
Identification of genetic variants (g789C>T and G111S) in the human HSPB2 gene.
Topics: Amino Acid Substitution; Cardiomyopathies; Crystallins; Cytosine; Glycine; Heat-Shock Proteins; Huma | 2001 |
Novel variant transthyretin gene (Ser50 to Ile) in familial cardiac amyloidosis.
Topics: Amyloidosis; Base Sequence; Cardiomyopathies; Cloning, Molecular; DNA; Electrophoresis, Polyacrylami | 1992 |