Page last updated: 2024-11-08

serine and Carcinoma, Pancreatic Ductal

serine has been researched along with Carcinoma, Pancreatic Ductal in 9 studies

Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.

Carcinoma, Pancreatic Ductal: Carcinoma that arises from the PANCREATIC DUCTS. It accounts for the majority of cancers derived from the PANCREAS.

Research Excerpts

ExcerptRelevanceReference
"Using in vitro and in vivo pancreatic cancer models, we show that IDO1 expression is highly context dependent, influenced by attachment-independent growth and the canonical activator IFNγ."1.62Immune-regulated IDO1-dependent tryptophan metabolism is source of one-carbon units for pancreatic cancer and stellate cells. ( Athineos, D; Blyth, K; Falcone, M; Huerta Uribe, A; Maddocks, ODK; Newman, AC; Pietzke, M; Vazquez, A; Zhang, T, 2021)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (22.22)24.3611
2020's7 (77.78)2.80

Authors

AuthorsStudies
Itoyama, R1
Yasuda-Yoshihara, N1
Kitamura, F1
Yasuda, T1
Bu, L1
Yonemura, A1
Uchihara, T1
Arima, K1
Hu, X1
Jun, Z1
Okamoto, Y1
Akiyama, T1
Yamashita, K1
Nakao, Y1
Yusa, T1
Kitano, Y1
Higashi, T1
Miyata, T1
Imai, K1
Hayashi, H1
Yamashita, YI1
Mikawa, T1
Kondoh, H1
Baba, H1
Ishimoto, T1
He, X1
Li, Y1
Chen, Q1
Zheng, L1
Lou, J1
Lin, C1
Gong, J1
Zhu, Y1
Wu, Y1
Zhu, Q1
Zhou, H1
Wu, L1
Lai, Z1
Geng, D1
Yang, W1
Zhang, J1
Fan, Z1
Qin, W1
Wang, Y1
Zhou, R1
Yi, W1
Xiao, Y1
Zhang, B1
Cloyd, JM1
Xu, G1
Du, S1
Mao, Y1
Pawlik, TM1
Banh, RS1
Biancur, DE1
Yamamoto, K1
Sohn, ASW1
Walters, B1
Kuljanin, M1
Gikandi, A1
Wang, H1
Mancias, JD1
Schneider, RJ1
Pacold, ME1
Kimmelman, AC1
Newman, AC1
Falcone, M1
Huerta Uribe, A1
Zhang, T1
Athineos, D1
Pietzke, M1
Vazquez, A1
Blyth, K1
Maddocks, ODK1
Omori, Y1
Ono, Y1
Morikawa, T1
Motoi, F1
Higuchi, R1
Yamamoto, M1
Hayakawa, Y1
Karasaki, H1
Mizukami, Y1
Unno, M1
Furukawa, T1
Kamphorst, JJ1
Nofal, M1
Commisso, C1
Hackett, SR1
Lu, W1
Grabocka, E1
Vander Heiden, MG1
Miller, G1
Drebin, JA1
Bar-Sagi, D1
Thompson, CB1
Rabinowitz, JD1
Bogyo, M1

Other Studies

9 other studies available for serine and Carcinoma, Pancreatic Ductal

ArticleYear
Metabolic shift to serine biosynthesis through 3-PG accumulation and PHGDH induction promotes tumor growth in pancreatic cancer.
    Cancer letters, 2021, 12-28, Volume: 523

    Topics: Animals; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; CpG Islands; DNA Methylation; Enzyme Induct

2021
O-GlcNAcylation and stablization of SIRT7 promote pancreatic cancer progression by blocking the SIRT7-REGγ interaction.
    Cell death and differentiation, 2022, Volume: 29, Issue:10

    Topics: Autoantigens; Carcinoma, Pancreatic Ductal; Cell Proliferation; Humans; N-Acetylglucosaminyltransfer

2022
O-GlcNAcylation promotes pancreatic tumor growth by regulating malate dehydrogenase 1.
    Nature chemical biology, 2022, Volume: 18, Issue:10

    Topics: Acetylglucosamine; Animals; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Glutamine; Malate Dehydr

2022
Gene signature and connectivity mapping to assist with drug prediction for pancreatic ductal adenocarcinoma.
    Surgical oncology, 2022, Volume: 44

    Topics: Aurora Kinase A; Biomarkers, Tumor; Carcinoma, Pancreatic Ductal; Computational Biology; Gene Expres

2022
Neurons Release Serine to Support mRNA Translation in Pancreatic Cancer.
    Cell, 2020, 11-25, Volume: 183, Issue:5

    Topics: Adenocarcinoma; Aged; Animals; Axons; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Prolifera

2020
Immune-regulated IDO1-dependent tryptophan metabolism is source of one-carbon units for pancreatic cancer and stellate cells.
    Molecular cell, 2021, 06-03, Volume: 81, Issue:11

    Topics: Allografts; Animals; Antineoplastic Agents; Carbon; Carcinoma, Pancreatic Ductal; Cell Line, Tumor;

2021
Serine/Threonine Kinase 11 Plays a Canonical Role in Malignant Progression of KRAS -Mutant and GNAS -Wild-Type Intraductal Papillary Mucinous Neoplasms of the Pancreas.
    Annals of surgery, 2023, 02-01, Volume: 277, Issue:2

    Topics: AMP-Activated Protein Kinases; Carcinoma, Pancreatic Ductal; Chromogranins; GTP-Binding Protein alph

2023
Human pancreatic cancer tumors are nutrient poor and tumor cells actively scavenge extracellular protein.
    Cancer research, 2015, Feb-01, Volume: 75, Issue:3

    Topics: Albumins; Amino Acids; Animals; Carcinoma, Pancreatic Ductal; Cell Proliferation; Chromatography, Li

2015
Finding enzymes that are actively involved in cancer.
    Proceedings of the National Academy of Sciences of the United States of America, 2010, Feb-09, Volume: 107, Issue:6

    Topics: Cadherins; Carcinoma, Pancreatic Ductal; Cell Cycle Proteins; Humans; Hydrolases; Intracellular Sign

2010