serine has been researched along with Carcinoma, Ovarian Epithelial in 3 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Carcinoma, Ovarian Epithelial: A malignant neoplasm that originates in cells on the surface EPITHELIUM of the ovary and is the most common form of ovarian cancer. There are five histologic subtypes: papillary serous, endometrioid, mucinous, clear cell, and transitional cell. Mutations in BRCA1, OPCML, PRKN, PIK3CA, AKT1, CTNNB1, RRAS2, and CDH1 genes are associated with this cancer.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Resistance to platinum-based chemotherapy represents a major clinical challenge for many tumors, including epithelial ovarian cancer." | 4.12 | Serine metabolism remodeling after platinum-based chemotherapy identifies vulnerabilities in a subgroup of resistant ovarian cancers. ( Agami, R; Amant, F; Annibali, D; Baiden-Amissah, REM; Berardi, E; Berkers, CR; Carmeliet, P; Davidson, B; De Wispelaere, W; Duarte, JAG; Eelen, G; Fendt, SM; Horlings, HM; Körner, PR; Lambrechts, D; Moens, S; Planque, M; Rizzotto, L; Rossi, M; Sonke, GS; Swinnen, JV; Talebi, A; Van Nyen, T; van Wagensveld, L; Zaal, EA, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Van Nyen, T | 1 |
| Planque, M | 1 |
| van Wagensveld, L | 1 |
| Duarte, JAG | 1 |
| Zaal, EA | 1 |
| Talebi, A | 1 |
| Rossi, M | 1 |
| Körner, PR | 1 |
| Rizzotto, L | 1 |
| Moens, S | 1 |
| De Wispelaere, W | 1 |
| Baiden-Amissah, REM | 1 |
| Sonke, GS | 1 |
| Horlings, HM | 1 |
| Eelen, G | 1 |
| Berardi, E | 1 |
| Swinnen, JV | 1 |
| Berkers, CR | 1 |
| Carmeliet, P | 1 |
| Lambrechts, D | 1 |
| Davidson, B | 1 |
| Agami, R | 1 |
| Fendt, SM | 1 |
| Annibali, D | 1 |
| Amant, F | 1 |
| Zaoui, K | 1 |
| Boudhraa, Z | 1 |
| Khalifé, P | 1 |
| Carmona, E | 1 |
| Provencher, D | 1 |
| Mes-Masson, AM | 1 |
| Wang, Y | 2 |
| Xiang, J | 1 |
| Ji, F | 1 |
| Deng, Y | 1 |
| Tang, C | 1 |
| Yang, S | 1 |
| Xi, Q | 1 |
| Liu, R | 1 |
| Di, W | 1 |
3 other studies available for serine and Carcinoma, Ovarian Epithelial
| Article | Year |
|---|---|
Serine metabolism remodeling after platinum-based chemotherapy identifies vulnerabilities in a subgroup of resistant ovarian cancers.
Topics: Carcinoma, Ovarian Epithelial; Drug Resistance, Neoplasm; Female; Humans; Neoplasm Recurrence, Local | 2022 |
Ran promotes membrane targeting and stabilization of RhoA to orchestrate ovarian cancer cell invasion.
Topics: Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cell Membrane; Female; Gene Knockdown Techniques; H | 2019 |
Knockdown of CRM1 inhibits the nuclear export of p27(Kip1) phosphorylated at serine 10 and plays a role in the pathogenesis of epithelial ovarian cancer.
Topics: Active Transport, Cell Nucleus; Adult; Animals; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cel | 2014 |