serine has been researched along with Carcinoma, Medullary in 6 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Carcinoma, Medullary: A carcinoma composed mainly of epithelial elements with little or no stroma. Medullary carcinomas of the breast constitute 5%-7% of all mammary carcinomas; medullary carcinomas of the thyroid comprise 3%-10% of all thyroid malignancies. (From Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1141; Segen, Dictionary of Modern Medicine, 1992)
| Excerpt | Relevance | Reference |
|---|---|---|
| "S891A mutation caused medullary thyroid cancer (MTC) in 69." | 1.36 | The clinical spectrum of multiple endocrine neoplasia type 2a caused by the rare intracellular RET mutation S891A. ( Aylwin, S; Beck-Peccoz, P; Diaz-Cano, S; Dralle, H; Fugazzola, L; Izatt, L; Machens, A; McGregor, A; Schulte, KM; Talat, N, 2010) |
| "All MEN 2A affected family members suffered from medullary thyroid carcinoma and two of ten patients for pheochromocytoma." | 1.33 | Novel germline mutation in the transmembrane region of RET gene close to Cys634Ser mutation associated with MEN 2A syndrome. ( Altaner, C; Altanerova, V; Breza, J; Kostalova, L; Poturnajova, M, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schulte, KM | 1 |
| Machens, A | 1 |
| Fugazzola, L | 1 |
| McGregor, A | 1 |
| Diaz-Cano, S | 1 |
| Izatt, L | 1 |
| Aylwin, S | 1 |
| Talat, N | 1 |
| Beck-Peccoz, P | 1 |
| Dralle, H | 1 |
| Mian, C | 1 |
| Sartorato, P | 1 |
| Barollo, S | 1 |
| Zane, M | 1 |
| Opocher, G | 1 |
| Elisei, R | 1 |
| Cosci, B | 1 |
| Romei, C | 1 |
| Bottici, V | 1 |
| Sculli, M | 1 |
| Lari, R | 1 |
| Barale, R | 1 |
| Pacini, F | 1 |
| Pinchera, A | 1 |
| Poturnajova, M | 1 |
| Altanerova, V | 1 |
| Kostalova, L | 1 |
| Breza, J | 1 |
| Altaner, C | 1 |
| Plaza-Menacho, I | 1 |
| van der Sluis, T | 1 |
| Hollema, H | 1 |
| Gimm, O | 1 |
| Buys, CH | 1 |
| Magee, AI | 1 |
| Isacke, CM | 1 |
| Hofstra, RM | 1 |
| Eggen, BJ | 1 |
| Cardot-Bauters, C | 1 |
| Leteurtre, E | 1 |
| Leclerc, L | 1 |
| Vantyghem, MC | 1 |
| Do Cao, C | 1 |
| Wemeau, JL | 1 |
| d'Herbomez, M | 1 |
| Carnaille, B | 1 |
| Barbu, V | 1 |
| Pinson, S | 1 |
| Pigny, P | 1 |
1 review available for serine and Carcinoma, Medullary
| Article | Year |
|---|---|
RET codon 609 mutations: a contribution for better clinical managing.
Topics: Carcinoma, Medullary; Carcinoma, Neuroendocrine; Codon; Cysteine; Genetic Association Studies; Germ- | 2012 |
5 other studies available for serine and Carcinoma, Medullary
| Article | Year |
|---|---|
The clinical spectrum of multiple endocrine neoplasia type 2a caused by the rare intracellular RET mutation S891A.
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Aged, 80 and over; Alanine; Amino Acid Substitutio | 2010 |
RET exon 11 (G691S) polymorphism is significantly more frequent in sporadic medullary thyroid carcinoma than in the general population.
Topics: Carcinoma, Medullary; Exons; Female; Genetic Variation; Glycine; Humans; Male; Mutation; Polymorphis | 2004 |
Novel germline mutation in the transmembrane region of RET gene close to Cys634Ser mutation associated with MEN 2A syndrome.
Topics: Adrenal Gland Neoplasms; Carcinoma, Medullary; Cysteine; Exons; Female; Gene Frequency; Genetic Link | 2005 |
Ras/ERK1/2-mediated STAT3 Ser727 phosphorylation by familial medullary thyroid carcinoma-associated RET mutants induces full activation of STAT3 and is required for c-fos promoter activation, cell mitogenicity, and transformation.
Topics: Animals; Carcinoma, Medullary; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Famil | 2007 |
Does the RET variant G691S influence the features of sporadic medullary thyroid carcinoma?
Topics: Adolescent; Adult; Age of Onset; Aged; Carcinoma, Medullary; Case-Control Studies; Female; Genetic V | 2008 |