serine has been researched along with Carcinoma, Ductal, Breast in 5 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Carcinoma, Ductal, Breast: An invasive (infiltrating) CARCINOMA of the mammary ductal system (MAMMARY GLANDS) in the human BREAST.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although it is known that STAT3 transcriptional activity is modulated by phosphorylation at serine residue 727, the role of STAT3 serine phosphorylation in breast cancer remains mostly unexplored." | 3.73 | STAT3 ser727 phosphorylation and its association with negative estrogen receptor status in breast infiltrating ductal carcinoma. ( Chen, IF; Chuang, HY; Hou, MF; Ou-Yang, F; Su, JH; Wang, YY; Yang, SF; Yeh, YT; Yuan, SS, 2006) |
| "However, treatments for triple negative breast cancer (TNBC) are lacking." | 1.46 | Phosphorylation of androgen receptors at serine 515 is a potential prognostic marker for triple negative breast cancer. ( Edwards, J; Liew, B; Lim, Z; Mallon, EA; McCall, P; Roseweir, AK; Scott, A, 2017) |
| "To study PKR function in human breast cancer, PKR activity was measured in mammary carcinoma cell lines and nontransformed mammary epithelial cell lines." | 1.31 | Human breast cancer cells contain elevated levels and activity of the protein kinase, PKR. ( Forman, AP; Gunnery, S; Kim, SH; Mathews, MB, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Roseweir, AK | 1 |
| McCall, P | 1 |
| Scott, A | 1 |
| Liew, B | 1 |
| Lim, Z | 1 |
| Mallon, EA | 1 |
| Edwards, J | 1 |
| Kumar, A | 1 |
| Rajendran, V | 1 |
| Sethumadhavan, R | 1 |
| Purohit, R | 1 |
| Yamashita, H | 1 |
| Nishio, M | 1 |
| Toyama, T | 1 |
| Sugiura, H | 1 |
| Kondo, N | 1 |
| Kobayashi, S | 1 |
| Fujii, Y | 1 |
| Iwase, H | 1 |
| Yeh, YT | 1 |
| Ou-Yang, F | 1 |
| Chen, IF | 1 |
| Yang, SF | 1 |
| Wang, YY | 1 |
| Chuang, HY | 1 |
| Su, JH | 1 |
| Hou, MF | 1 |
| Yuan, SS | 1 |
| Kim, SH | 1 |
| Forman, AP | 1 |
| Mathews, MB | 1 |
| Gunnery, S | 1 |
5 other studies available for serine and Carcinoma, Ductal, Breast
| Article | Year |
|---|---|
Phosphorylation of androgen receptors at serine 515 is a potential prognostic marker for triple negative breast cancer.
Topics: Biomarkers, Tumor; Carcinoma, Ductal, Breast; CDC2 Protein Kinase; Cohort Studies; Extracellular Sig | 2017 |
Relationship between a point mutation S97C in CK1δ protein and its affect on ATP-binding affinity.
Topics: Adenosine Triphosphate; Breast Neoplasms; Carcinoma, Ductal, Breast; Casein Kinase Idelta; Computer | 2014 |
Low phosphorylation of estrogen receptor alpha (ERalpha) serine 118 and high phosphorylation of ERalpha serine 167 improve survival in ER-positive breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Breast Neoplasms | 2008 |
STAT3 ser727 phosphorylation and its association with negative estrogen receptor status in breast infiltrating ductal carcinoma.
Topics: Biomarkers, Tumor; Breast Neoplasms; Carcinoma, Ductal, Breast; Female; Gene Expression Regulation, | 2006 |
Human breast cancer cells contain elevated levels and activity of the protein kinase, PKR.
Topics: Blotting, Western; Breast; Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Line, Transformed; eIF- | 2000 |