Page last updated: 2024-11-08

serine and Carcinoma, Anaplastic

serine has been researched along with Carcinoma, Anaplastic in 31 studies

Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
" We aimed to explore the role of histone H3 phosphorylation at serine10 (p-H3Ser10) in Epstein-Barr virus (EBV) latent membrane protein-1 (LMP1)-induced carcinogenesis of nasopharyngeal carcinoma (NPC)."7.79Increased phosphorylation of histone H3 at serine 10 is involved in Epstein-Barr virus latent membrane protein-1-induced carcinogenesis of nasopharyngeal carcinoma. ( Dong, Z; He, Z; Huang, G; Li, B; Li, R; Wang, J; Zhang, X, 2013)
"Radiation is an effective treatment against nasopharyngeal carcinoma (NPC)."5.43Prognostic value of phosphorylated Raf kinase inhibitory protein at serine 153 and its predictive effect on the clinical response to radiotherapy in nasopharyngeal carcinoma. ( Chen, Q; Guo, X; He, Z; Hou, Q; Li, S; Liu, M; Liu, T; Liu, Z; Mo, W; Wang, H; Xia, W; Zeng, M; Zhao, H; Zhou, Y, 2016)
" We aimed to explore the role of histone H3 phosphorylation at serine10 (p-H3Ser10) in Epstein-Barr virus (EBV) latent membrane protein-1 (LMP1)-induced carcinogenesis of nasopharyngeal carcinoma (NPC)."3.79Increased phosphorylation of histone H3 at serine 10 is involved in Epstein-Barr virus latent membrane protein-1-induced carcinogenesis of nasopharyngeal carcinoma. ( Dong, Z; He, Z; Huang, G; Li, B; Li, R; Wang, J; Zhang, X, 2013)
"Radiation is an effective treatment against nasopharyngeal carcinoma (NPC)."1.43Prognostic value of phosphorylated Raf kinase inhibitory protein at serine 153 and its predictive effect on the clinical response to radiotherapy in nasopharyngeal carcinoma. ( Chen, Q; Guo, X; He, Z; Hou, Q; Li, S; Liu, M; Liu, T; Liu, Z; Mo, W; Wang, H; Xia, W; Zeng, M; Zhao, H; Zhou, Y, 2016)
"The prognostic abilities of breast cancer gene expression signatures are due mostly to the detection of proliferation activity."1.36Serine 2481-autophosphorylation of mammalian target of rapamycin (mTOR) couples with chromosome condensation and segregation during mitosis: confocal microscopy characterization and immunohistochemical validation of PP-mTOR(Ser2481) as a novel high-contra ( Bernadó, L; Lopez-Bonet, E; Menendez, JA; Oliveras-Ferraros, C; Pérez-Bueno, F; Pérez-Martínez, MC; Vazquez-Martin, A, 2010)
"Human breast cancer cells T47D release great amount of nitric oxide (NO), but its relation to tumor suppressor Rb is unknown."1.32Inactivated tumor suppressor Rb by nitric oxide promotes mitosis in human breast cancer cells. ( Radisavljevic, Z, 2004)
"SW480 colon cancer cells that express a truncated APC, at position 1338, contain high levels of pbeta-catenin, whereas HT29 cells, expressing APC truncated at position 1555, accumulate non-phosphorylated beta-catenin, suggesting that the 1338-1555 amino acid region of APC is involved in the differential regulation of the dephosphorylation and degradation of pbeta-catenin."1.31Regulation of S33/S37 phosphorylated beta-catenin in normal and transformed cells. ( Ben-Ze'ev, A; Conacci-Sorrell, M; Geiger, B; Kam, Z; Lando, Z; Sadot, E; Shnizer, D; Zharhary, D; Zhurinsky, J, 2002)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19908 (25.81)18.7374
1990's2 (6.45)18.2507
2000's12 (38.71)29.6817
2010's8 (25.81)24.3611
2020's1 (3.23)2.80

Authors

AuthorsStudies
Hong, X1
Li, Q1
Li, J1
Chen, K1
He, Q1
Zhao, Y2
Liang, Y1
Qiao, H1
Liu, N1
Ma, J1
Li, Y1
Li, B1
Huang, G1
Zhang, X1
Li, R1
Wang, J1
Dong, Z1
He, Z2
Clauditz, TS1
Gontarewicz, A1
Bokemeyer, C1
Sauter, G1
Knecht, R1
Münscher, A1
Wilczak, W1
Sun, WY1
Kim, HM1
Jung, WH1
Koo, JS1
Li, S1
Liu, T1
Mo, W1
Hou, Q1
Zhou, Y1
Liu, M1
Liu, Z1
Chen, Q1
Wang, H1
Guo, X1
Xia, W1
Zeng, M1
Zhao, H1
Holm, C1
Kok, M1
Michalides, R1
Fles, R1
Koornstra, RH1
Wesseling, J1
Hauptmann, M1
Neefjes, J1
Peterse, JL1
Stål, O1
Landberg, G1
Linn, SC1
Lopez-Bonet, E1
Vazquez-Martin, A1
Pérez-Martínez, MC1
Oliveras-Ferraros, C1
Pérez-Bueno, F1
Bernadó, L1
Menendez, JA1
Zhang, D1
Tari, AM1
Akar, U1
Arun, BK1
LaFortune, TA1
Nieves-Alicea, R1
Hortobagyi, GN1
Ueno, NT1
Faustino, A1
Couto, JP1
Pópulo, H1
Rocha, AS1
Pardal, F1
Cameselle-Teijeiro, JM1
Lopes, JM1
Sobrinho-Simões, M1
Soares, P1
Hvid, H1
Fendt, SM1
Blouin, MJ1
Birman, E1
Voisin, G1
Svendsen, AM1
Frank, R1
Vander Heiden, MG1
Stephanopoulos, G1
Hansen, BF1
Pollak, M1
JACQUEZ, JA1
SARTORELLI, AC1
LePAGE, GA1
NYHAN, WL1
LOH HOEHN-SARIC, E1
ILAN, J1
JOHNSTONE, RM2
HERSCOVICS, A1
Radisavljevic, Z1
Rieger-Christ, KM1
Lee, P1
Zagha, R1
Kosakowski, M1
Moinzadeh, A1
Stoffel, J1
Ben-Ze'ev, A2
Libertino, JA1
Summerhayes, IC1
Bruins, W1
Zwart, E1
Attardi, LD1
Iwakuma, T1
Hoogervorst, EM1
Beems, RB1
Miranda, B1
van Oostrom, CT1
van den Berg, J1
van den Aardweg, GJ1
Lozano, G1
van Steeg, H1
Jacks, T1
de Vries, A1
Ramírez, CJ1
Haberbusch, JM1
Soprano, DR1
Soprano, KJ1
Vernez, M1
Hutter, P1
Monnerat, C1
Halkic, N1
Gugerli, O1
Bouzourene, H1
Petterino, C1
Podestà, G1
Ratto, A1
Drigo, M1
Pellegrino, C1
Kawatsu, M1
Yamashita, T1
Osono, M1
Masuda, T1
Ishizuka, M1
Takeuchi, T1
Rabbani, F1
Richon, VM1
Orlow, I1
Lu, ML1
Drobnjak, M1
Dudas, M1
Charytonowicz, E1
Dalbagni, G1
Cordon-Cardo, C1
Tanyi, J1
Páy, A1
Rigó, J1
Nagy, B1
Papp, Z1
Yang, CP1
Horwitz, SB1
Fournès, B1
Sadekova, S1
Turbide, C1
Létourneau, S1
Beauchemin, N1
Sadot, E1
Conacci-Sorrell, M1
Zhurinsky, J1
Shnizer, D1
Lando, Z1
Zharhary, D1
Kam, Z1
Geiger, B1
Hori, K1
Saito, S1
Kubota, K1
Morris, VL1
Wagner, EK1
Roizman, B1
Pizer, LI1
Regan, JD1
Spellman, CM1
Fottrell, PF1

Other Studies

31 other studies available for serine and Carcinoma, Anaplastic

ArticleYear
CircIPO7 Promotes Nasopharyngeal Carcinoma Metastasis and Cisplatin Chemoresistance by Facilitating YBX1 Nuclear Localization.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2022, 10-14, Volume: 28, Issue:20

    Topics: Carcinoma; Cell Line, Tumor; Cisplatin; Drug Resistance, Neoplasm; Gene Expression Regulation, Neopl

2022
Increased phosphorylation of histone H3 at serine 10 is involved in Epstein-Barr virus latent membrane protein-1-induced carcinogenesis of nasopharyngeal carcinoma.
    BMC cancer, 2013, Mar-18, Volume: 13

    Topics: Adult; Carcinoma; Cell Line; Cell Transformation, Viral; Female; Gene Expression; Histones; Humans;

2013
Abundant expression of mTOR kinase in salivary gland tumors - potentials as therapy target?
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2013, Volume: 42, Issue:10

    Topics: Adenoma; Adult; Carcinoma; Carcinoma, Mucoepidermoid; Female; Gene Expression Regulation, Enzymologi

2013
Expression of serine/glycine metabolism-related proteins is different according to the thyroid cancer subtype.
    Journal of translational medicine, 2016, 06-08, Volume: 14, Issue:1

    Topics: Carcinoma; Carcinoma, Papillary; Disease-Free Survival; Glutamine; Glycine; Humans; Mutation; Neopla

2016
Prognostic value of phosphorylated Raf kinase inhibitory protein at serine 153 and its predictive effect on the clinical response to radiotherapy in nasopharyngeal carcinoma.
    Radiation oncology (London, England), 2016, Sep-20, Volume: 11, Issue:1

    Topics: Adult; Aged; Biopsy; Carcinoma; Cohort Studies; Disease-Free Survival; Drug Resistance, Neoplasm; Fe

2016
Phosphorylation of the oestrogen receptor alpha at serine 305 and prediction of tamoxifen resistance in breast cancer.
    The Journal of pathology, 2009, Volume: 217, Issue:3

    Topics: Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Blotting, Western; Breast Neoplasms; Carcinoma;

2009
Serine 2481-autophosphorylation of mammalian target of rapamycin (mTOR) couples with chromosome condensation and segregation during mitosis: confocal microscopy characterization and immunohistochemical validation of PP-mTOR(Ser2481) as a novel high-contra
    International journal of oncology, 2010, Volume: 36, Issue:1

    Topics: Biopsy; Breast Neoplasms; Carcinoma; Cell Nucleus; Chromosomes; Cytoplasm; Genetic Markers; HeLa Cel

2010
Silencing kinase-interacting stathmin gene enhances erlotinib sensitivity by inhibiting Ser¹⁰ p27 phosphorylation in epidermal growth factor receptor-expressing breast cancer.
    Molecular cancer therapeutics, 2010, Volume: 9, Issue:11

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Cyclin-Dependent Kina

2010
mTOR pathway overactivation in BRAF mutated papillary thyroid carcinoma.
    The Journal of clinical endocrinology and metabolism, 2012, Volume: 97, Issue:7

    Topics: Amino Acid Substitution; Carcinoma; Carcinoma, Papillary; Cell Line, Tumor; Gene Expression Regulati

2012
Stimulation of MC38 tumor growth by insulin analog X10 involves the serine synthesis pathway.
    Endocrine-related cancer, 2012, Volume: 19, Issue:4

    Topics: Animals; Carcinoma; Cell Line, Tumor; Cell Proliferation; Colon; Colonic Neoplasms; Gene Expression

2012
Active transport of O-diazoacetyl-L-serine and 6-diazo-5-oxo-L-norleucine in Ehrlich ascites carcinoma.
    Cancer research, 1957, Volume: 17, Issue:9

    Topics: Antineoplastic Agents; Ascites; Azaserine; Biological Transport, Active; Carcinoma; Diazooxonorleuci

1957
The development and biochemical characterization of resistance to azaserine in a TA 3 ascites carcinoma.
    Cancer research, 1958, Volume: 18, Issue:4

    Topics: Animals; Antineoplastic Agents; Ascites; Azaserine; Carcinoma; Neoplasms, Experimental; Serine

1958
Effects of nitrogen mustards on the incorporation of amino acids into the proteins of tumors and other tissues; the mustard derivative of serine.
    Biochemical pharmacology, 1963, Volume: 12

    Topics: Amino Acids; Animals; Carcinoma; Carcinoma 256, Walker; Humans; Mechlorethamine; Methionine; Mustard

1963
METABOLISM OF EHRLICH ASCITES CARCINOMA CELLS GROWN IN MICE ON A MEAT DIET.
    Nature, 1964, Dec-12, Volume: 204

    Topics: Animals; Ascites; Carbon Isotopes; Carcinoma; Carcinoma, Ehrlich Tumor; Diet; Dietary Proteins; Form

1964
MECHANISM OF ACTION OF GLUCOSE AND PYRIMIDINE NUCLEOSIDES ON (14C)FORMATE UTILIZATION BY EHRLICH ASCITES CELLS.
    Biochimica et biophysica acta, 1964, Nov-15, Volume: 91

    Topics: Animals; Ascites; Carcinoma; Carcinoma, Ehrlich Tumor; Formates; Glucose; Glutamine; Metabolism; Nuc

1964
Inactivated tumor suppressor Rb by nitric oxide promotes mitosis in human breast cancer cells.
    Journal of cellular biochemistry, 2004, May-01, Volume: 92, Issue:1

    Topics: Arginine; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Female; Humans; Mitosis; Nitric Oxide; omeg

2004
Novel expression of N-cadherin elicits in vitro bladder cell invasion via the Akt signaling pathway.
    Oncogene, 2004, Jun-10, Volume: 23, Issue:27

    Topics: Blotting, Western; Cadherins; Carcinoma; Cell Line, Tumor; Chromones; Clone Cells; Collagen; Drug Co

2004
Increased sensitivity to UV radiation in mice with a p53 point mutation at Ser389.
    Molecular and cellular biology, 2004, Volume: 24, Issue:20

    Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Carcinoma; Cell Cycle; Cells, Cultured; Doxorubicin

2004
Retinoic acid induced repression of AP-1 activity is mediated by protein phosphatase 2A in ovarian carcinoma cells.
    Journal of cellular biochemistry, 2005, Sep-01, Volume: 96, Issue:1

    Topics: Carcinoma; Cell Line, Tumor; Dimerization; Down-Regulation; Female; Humans; JNK Mitogen-Activated Pr

2005
A case of Muir-Torre syndrome associated with mucinous hepatic cholangiocarcinoma and a novel germline mutation of the MSH2 gene.
    Familial cancer, 2007, Volume: 6, Issue:1

    Topics: Adenocarcinoma, Mucinous; Adenoma; Adult; Brain Neoplasms; Carcinoma; Cholangiocarcinoma; Colorectal

2007
Immunohistochemical study of phospho-Stat3-ser727 expression in feline mammary gland tumours.
    Veterinary research communications, 2007, Volume: 31, Issue:2

    Topics: Animals; Carcinoma; Cat Diseases; Cats; Female; Immunohistochemistry; Mammary Neoplasms, Animal; Pho

2007
Effect of conagenin in tumor bearing mice. Antitumor activity, generation of effector cells and cytokine production.
    The Journal of antibiotics, 1993, Volume: 46, Issue:11

    Topics: Adjuvants, Immunologic; Animals; Carcinoma; Cytokines; Killer Cells, Natural; Mice; Mice, Inbred BAL

1993
Prognostic significance of transcription factor E2F-1 in bladder cancer: genotypic and phenotypic characterization.
    Journal of the National Cancer Institute, 1999, May-19, Volume: 91, Issue:10

    Topics: Carcinoma; Carrier Proteins; Cell Cycle Proteins; DNA-Binding Proteins; E2F Transcription Factors; E

1999
[Mutation analysis of the beta-catenin gene in epithelial carcinomas of the ovaries].
    Orvosi hetilap, 2000, May-21, Volume: 141, Issue:21

    Topics: Adult; Age Factors; Aged; beta Catenin; Cadherins; Carcinoma; Cytoskeletal Proteins; DNA, Neoplasm;

2000
Taxol mediates serine phosphorylation of the 66-kDa Shc isoform.
    Cancer research, 2000, Sep-15, Volume: 60, Issue:18

    Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Antineoplastic Agents,

2000
The CEACAM1-L Ser503 residue is crucial for inhibition of colon cancer cell tumorigenicity.
    Oncogene, 2001, Jan-11, Volume: 20, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amino Acid Sequence; Animals; Antigens, CD; Antigens,

2001
Regulation of S33/S37 phosphorylated beta-catenin in normal and transformed cells.
    Journal of cell science, 2002, Jul-01, Volume: 115, Issue:Pt 13

    Topics: Adenomatous Polyposis Coli Protein; Amino Acid Sequence; Animals; beta Catenin; beta-Transducin Repe

2002
A novel combretastatin A-4 derivative, AC7700, strongly stanches tumour blood flow and inhibits growth of tumours developing in various tissues and organs.
    British journal of cancer, 2002, May-20, Volume: 86, Issue:10

    Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma; Drug Screening Assays, Antitumor; Heart Neopl

2002
RNA synthesis in cells infected with herpes simplex virus. 3. Absence of virus-specified arginyl- and seryl-tRNA in infected HEp-2 cells.
    Journal of molecular biology, 1970, Sep-14, Volume: 52, Issue:2

    Topics: Arginine; Carcinoma; Cell Line; Chromatography; Chromatography, Gel; Culture Techniques; DNA, Viral;

1970
Basis for the serine requirement in leukemic and normal human leukocytes. Reduced levels of the enzymes in the phosphorylated pathway.
    Journal of the National Cancer Institute, 1972, Volume: 48, Issue:6

    Topics: Carbon Isotopes; Carcinoma; Cell Line; Fibroblasts; Glycerolphosphate Dehydrogenase; HeLa Cells; Hum

1972
Similarities between pyruvate kinase from human placenta and tumours.
    FEBS letters, 1973, Dec-01, Volume: 37, Issue:2

    Topics: Adenosine Triphosphate; Alanine; Carcinoma; Chromatography, Gel; Chromatography, Ion Exchange; Elect

1973