Page last updated: 2024-11-08

serine and Cancer of the Thyroid

serine has been researched along with Cancer of the Thyroid in 14 studies

Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
"(PV) in the treatment of papillary thyroid carcinoma (PTC) by using network pharmacology combined with molecular docking verification."1.91Investigation of the mechanism of Prunella vulgaris in treatment of papillary thyroid carcinoma based on network pharmacology integrated molecular docking and experimental verification. ( Huang, Y; Li, Y; Mao, J; Wang, X; Zhu, X, 2023)
"S891A mutation caused medullary thyroid cancer (MTC) in 69."1.36The clinical spectrum of multiple endocrine neoplasia type 2a caused by the rare intracellular RET mutation S891A. ( Aylwin, S; Beck-Peccoz, P; Diaz-Cano, S; Dralle, H; Fugazzola, L; Izatt, L; Machens, A; McGregor, A; Schulte, KM; Talat, N, 2010)
"All MEN 2A affected family members suffered from medullary thyroid carcinoma and two of ten patients for pheochromocytoma."1.33Novel germline mutation in the transmembrane region of RET gene close to Cys634Ser mutation associated with MEN 2A syndrome. ( Altaner, C; Altanerova, V; Breza, J; Kostalova, L; Poturnajova, M, 2005)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.14)18.2507
2000's4 (28.57)29.6817
2010's7 (50.00)24.3611
2020's2 (14.29)2.80

Authors

AuthorsStudies
Xu, X3
Sun, T3
Jing, J3
Zhu, X1
Li, Y1
Wang, X1
Huang, Y1
Mao, J1
Liu, T1
Zhao, Y1
Wang, L1
Jia, H1
Cui, D1
Si, Y1
Wang, H1
Xue, H1
Sun, WY1
Kim, HM1
Jung, WH1
Koo, JS1
Schulte, KM1
Machens, A1
Fugazzola, L1
McGregor, A1
Diaz-Cano, S1
Izatt, L1
Aylwin, S1
Talat, N1
Beck-Peccoz, P1
Dralle, H1
Faustino, A1
Couto, JP1
Pópulo, H1
Rocha, AS1
Pardal, F1
Cameselle-Teijeiro, JM1
Lopes, JM1
Sobrinho-Simões, M1
Soares, P1
Liu, J1
Brown, RE1
Mian, C1
Sartorato, P1
Barollo, S1
Zane, M1
Opocher, G1
Li, N1
Du, ZX1
Zong, ZH1
Liu, BQ1
Li, C1
Zhang, Q1
Wang, HQ1
Elisei, R1
Cosci, B1
Romei, C1
Bottici, V1
Sculli, M1
Lari, R1
Barale, R1
Pacini, F1
Pinchera, A1
Poturnajova, M1
Altanerova, V1
Kostalova, L1
Breza, J1
Altaner, C1
Plaza-Menacho, I1
van der Sluis, T1
Hollema, H1
Gimm, O1
Buys, CH1
Magee, AI1
Isacke, CM1
Hofstra, RM1
Eggen, BJ1
Cardot-Bauters, C1
Leteurtre, E1
Leclerc, L1
Vantyghem, MC1
Do Cao, C1
Wemeau, JL1
d'Herbomez, M1
Carnaille, B1
Barbu, V1
Pinson, S1
Pigny, P1
Kopp, P1
Muirhead, S1
Jourdain, N1
Gu, WX1
Jameson, JL1
Rodd, C1

Reviews

1 review available for serine and Cancer of the Thyroid

ArticleYear
RET codon 609 mutations: a contribution for better clinical managing.
    Clinics (Sao Paulo, Brazil), 2012, Volume: 67 Suppl 1

    Topics: Carcinoma, Medullary; Carcinoma, Neuroendocrine; Codon; Cysteine; Genetic Association Studies; Germ-

2012

Other Studies

13 other studies available for serine and Cancer of the Thyroid

ArticleYear
TMPRSS4 is a novel biomarker and correlated with immune infiltration in thyroid carcinoma.
    BMC endocrine disorders, 2022, Nov-16, Volume: 22, Issue:1

    Topics: Biomarkers; Biomarkers, Tumor; Epithelial-Mesenchymal Transition; Humans; Membrane Proteins; Peptide

2022
TMPRSS4 is a novel biomarker and correlated with immune infiltration in thyroid carcinoma.
    BMC endocrine disorders, 2022, Nov-16, Volume: 22, Issue:1

    Topics: Biomarkers; Biomarkers, Tumor; Epithelial-Mesenchymal Transition; Humans; Membrane Proteins; Peptide

2022
TMPRSS4 is a novel biomarker and correlated with immune infiltration in thyroid carcinoma.
    BMC endocrine disorders, 2022, Nov-16, Volume: 22, Issue:1

    Topics: Biomarkers; Biomarkers, Tumor; Epithelial-Mesenchymal Transition; Humans; Membrane Proteins; Peptide

2022
TMPRSS4 is a novel biomarker and correlated with immune infiltration in thyroid carcinoma.
    BMC endocrine disorders, 2022, Nov-16, Volume: 22, Issue:1

    Topics: Biomarkers; Biomarkers, Tumor; Epithelial-Mesenchymal Transition; Humans; Membrane Proteins; Peptide

2022
TMPRSS4 is a novel biomarker and correlated with immune infiltration in thyroid carcinoma.
    BMC endocrine disorders, 2022, Nov-16, Volume: 22, Issue:1

    Topics: Biomarkers; Biomarkers, Tumor; Epithelial-Mesenchymal Transition; Humans; Membrane Proteins; Peptide

2022
TMPRSS4 is a novel biomarker and correlated with immune infiltration in thyroid carcinoma.
    BMC endocrine disorders, 2022, Nov-16, Volume: 22, Issue:1

    Topics: Biomarkers; Biomarkers, Tumor; Epithelial-Mesenchymal Transition; Humans; Membrane Proteins; Peptide

2022
TMPRSS4 is a novel biomarker and correlated with immune infiltration in thyroid carcinoma.
    BMC endocrine disorders, 2022, Nov-16, Volume: 22, Issue:1

    Topics: Biomarkers; Biomarkers, Tumor; Epithelial-Mesenchymal Transition; Humans; Membrane Proteins; Peptide

2022
TMPRSS4 is a novel biomarker and correlated with immune infiltration in thyroid carcinoma.
    BMC endocrine disorders, 2022, Nov-16, Volume: 22, Issue:1

    Topics: Biomarkers; Biomarkers, Tumor; Epithelial-Mesenchymal Transition; Humans; Membrane Proteins; Peptide

2022
TMPRSS4 is a novel biomarker and correlated with immune infiltration in thyroid carcinoma.
    BMC endocrine disorders, 2022, Nov-16, Volume: 22, Issue:1

    Topics: Biomarkers; Biomarkers, Tumor; Epithelial-Mesenchymal Transition; Humans; Membrane Proteins; Peptide

2022
Investigation of the mechanism of Prunella vulgaris in treatment of papillary thyroid carcinoma based on network pharmacology integrated molecular docking and experimental verification.
    Medicine, 2023, Apr-25, Volume: 102, Issue:17

    Topics: Drugs, Chinese Herbal; Humans; Interleukin-6; Kaempferols; Luteolin; Medicine, Chinese Traditional;

2023
[Effects of serine/threonine-protein kinase B-Raf-activated long-chain non-coding RNA on apoptosis and autophagy in thyroid carcinoma cells].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2018, Jul-28, Volume: 43, Issue:7

    Topics: Apoptosis; Autophagy; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Neoplasm I

2018
Expression of serine/glycine metabolism-related proteins is different according to the thyroid cancer subtype.
    Journal of translational medicine, 2016, 06-08, Volume: 14, Issue:1

    Topics: Carcinoma; Carcinoma, Papillary; Disease-Free Survival; Glutamine; Glycine; Humans; Mutation; Neopla

2016
The clinical spectrum of multiple endocrine neoplasia type 2a caused by the rare intracellular RET mutation S891A.
    The Journal of clinical endocrinology and metabolism, 2010, Volume: 95, Issue:9

    Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Aged, 80 and over; Alanine; Amino Acid Substitutio

2010
mTOR pathway overactivation in BRAF mutated papillary thyroid carcinoma.
    The Journal of clinical endocrinology and metabolism, 2012, Volume: 97, Issue:7

    Topics: Amino Acid Substitution; Carcinoma; Carcinoma, Papillary; Cell Line, Tumor; Gene Expression Regulati

2012
Morphoproteomic confirmation of an activated nuclear factor-кBp65 pathway in follicular thyroid carcinoma.
    International journal of clinical and experimental pathology, 2012, Volume: 5, Issue:3

    Topics: Adenocarcinoma, Follicular; Cell Nucleus; Cyclooxygenase 2; Cytoplasm; Glutathione S-Transferase pi;

2012
PKCδ-mediated phosphorylation of BAG3 at Ser187 site induces epithelial-mesenchymal transition and enhances invasiveness in thyroid cancer FRO cells.
    Oncogene, 2013, Sep-19, Volume: 32, Issue:38

    Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis Regulatory Proteins; Cell Line, Tumor; Cell

2013
RET exon 11 (G691S) polymorphism is significantly more frequent in sporadic medullary thyroid carcinoma than in the general population.
    The Journal of clinical endocrinology and metabolism, 2004, Volume: 89, Issue:7

    Topics: Carcinoma, Medullary; Exons; Female; Genetic Variation; Glycine; Humans; Male; Mutation; Polymorphis

2004
Novel germline mutation in the transmembrane region of RET gene close to Cys634Ser mutation associated with MEN 2A syndrome.
    Journal of molecular medicine (Berlin, Germany), 2005, Volume: 83, Issue:4

    Topics: Adrenal Gland Neoplasms; Carcinoma, Medullary; Cysteine; Exons; Female; Gene Frequency; Genetic Link

2005
Ras/ERK1/2-mediated STAT3 Ser727 phosphorylation by familial medullary thyroid carcinoma-associated RET mutants induces full activation of STAT3 and is required for c-fos promoter activation, cell mitogenicity, and transformation.
    The Journal of biological chemistry, 2007, Mar-02, Volume: 282, Issue:9

    Topics: Animals; Carcinoma, Medullary; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Famil

2007
Does the RET variant G691S influence the features of sporadic medullary thyroid carcinoma?
    Clinical endocrinology, 2008, Volume: 69, Issue:3

    Topics: Adolescent; Adult; Age of Onset; Aged; Carcinoma, Medullary; Case-Control Studies; Female; Genetic V

2008
Congenital hyperthyroidism caused by a solitary toxic adenoma harboring a novel somatic mutation (serine281-->isoleucine) in the extracellular domain of the thyrotropin receptor.
    The Journal of clinical investigation, 1997, Sep-15, Volume: 100, Issue:6

    Topics: Adenoma; Cells, Cultured; Cyclic AMP; Humans; Hyperthyroidism; Infant, Newborn; Isoleucine; Male; Mu

1997