serine has been researched along with Cancer of Head in 11 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Most oral cancers are squamous cell carcinomas that predominantly develop from cell hyperplasias and dysplasias." | 1.46 | S4S8-RPA phosphorylation as an indicator of cancer progression in oral squamous cell carcinomas. ( Byrne, BM; DiMaio, DJ; Giannini, P; Glanzer, JG; Kapil, S; Kumm, P; Liu, S; Oakley, GG; Rector, J; Smith, LM; Smith, RB; Treude, KJ, 2017) |
| "Head and neck squamous cell carcinoma (HNSCC) is frequently characterized by high resistance to radiotherapy, which critically depends on both altered signaling pathways within tumor cells and their dynamic interaction with the tumor microenvironment." | 1.42 | Phosphorylation of AKT(Ser473) serves as an independent prognostic marker for radiosensitivity in advanced head and neck squamous cell carcinoma. ( Dyckhoff, G; Freier, K; Freudlsperger, C; Grabe, N; Hess, J; Hoffmann, J; Horn, D; Plinkert, P; Saure, D; Sharma, S; Weber, KJ; Weichert, W; Weißfuß, S, 2015) |
| "A panel of HNSCC cell lines was determined with anoikis assays, and orthotopic mouse experiments were performed." | 1.39 | Serine substitution of proline at codon 151 of TP53 confers gain of function activity leading to anoikis resistance and tumor progression of head and neck cancer cells. ( Brennan, RG; Jasser, SA; Myers, JN; Sano, D; Xie, TX; Zhao, M; Zhou, G, 2013) |
| "We found that aggressive head and neck cancers exhibited overexpression and stabilization of Aur-A protein without gene amplification or mRNA overexpression." | 1.34 | Constitutive phosphorylation of aurora-a on ser51 induces its stabilization and consequent overexpression in cancer. ( Kawai, H; Kitajima, S; Kudo, Y; Ogawa, I; Pagano, M; Takata, T; Tatsuka, M, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 4 (36.36) | 24.3611 |
| 2020's | 3 (27.27) | 2.80 |
| Authors | Studies |
|---|---|
| Jin, Y | 1 |
| Jung, SN | 1 |
| Lim, MA | 1 |
| Oh, C | 1 |
| Piao, Y | 1 |
| Kim, HJ | 1 |
| Nguyena, Q | 1 |
| Kang, YE | 1 |
| Chang, JW | 1 |
| Won, HR | 1 |
| Koo, BS | 1 |
| Hu, L | 1 |
| Hu, J | 1 |
| Huang, Y | 1 |
| Zheng, S | 1 |
| Yin, J | 1 |
| Li, X | 1 |
| Li, D | 1 |
| Lv, C | 1 |
| Li, S | 1 |
| Hu, W | 1 |
| Sharif Siam, MK | 1 |
| Sarker, A | 1 |
| Sayeem, MMS | 1 |
| Xie, TX | 1 |
| Zhou, G | 1 |
| Zhao, M | 1 |
| Sano, D | 1 |
| Jasser, SA | 1 |
| Brennan, RG | 1 |
| Myers, JN | 1 |
| Freudlsperger, C | 1 |
| Horn, D | 1 |
| Weißfuß, S | 1 |
| Weichert, W | 1 |
| Weber, KJ | 1 |
| Saure, D | 1 |
| Sharma, S | 1 |
| Dyckhoff, G | 1 |
| Grabe, N | 1 |
| Plinkert, P | 1 |
| Hoffmann, J | 1 |
| Freier, K | 1 |
| Hess, J | 1 |
| Rector, J | 1 |
| Kapil, S | 1 |
| Treude, KJ | 1 |
| Kumm, P | 1 |
| Glanzer, JG | 1 |
| Byrne, BM | 1 |
| Liu, S | 1 |
| Smith, LM | 1 |
| DiMaio, DJ | 1 |
| Giannini, P | 1 |
| Smith, RB | 1 |
| Oakley, GG | 1 |
| Arun, P | 1 |
| Brown, MS | 1 |
| Ehsanian, R | 1 |
| Chen, Z | 1 |
| Van Waes, C | 1 |
| Clémenson, C | 1 |
| Jouannot, E | 1 |
| Merino-Trigo, A | 1 |
| Rubin-Carrez, C | 1 |
| Deutsch, E | 1 |
| Hapke, G | 1 |
| Yin, MB | 1 |
| Wu, J | 1 |
| Frank, C | 1 |
| Rustum, YM | 1 |
| Hashimoto, T | 1 |
| Uchida, K | 1 |
| Okayama, N | 1 |
| Imate, Y | 1 |
| Suehiro, Y | 1 |
| Hamanaka, Y | 1 |
| Ueyama, Y | 1 |
| Yamashita, H | 1 |
| Hinoda, Y | 1 |
| Kitajima, S | 1 |
| Kudo, Y | 1 |
| Ogawa, I | 1 |
| Tatsuka, M | 1 |
| Kawai, H | 1 |
| Pagano, M | 1 |
| Takata, T | 1 |
1 review available for serine and Cancer of Head
| Article | Year |
|---|---|
Hypoxia-mediated activation of hypoxia-inducible factor-1α in head and neck squamous cell carcinoma: A review.
Topics: Head and Neck Neoplasms; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Phosphatidylino | 2023 |
10 other studies available for serine and Cancer of Head
| Article | Year |
|---|---|
SHMT2 Induces Stemness and Progression of Head and Neck Cancer.
Topics: Cell Proliferation; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Male; N | 2022 |
Topics: Carcinoma, Squamous Cell; Cytochrome P-450 Enzyme System; Drug Design; Head and Neck Neoplasms; Huma | 2021 |
Serine substitution of proline at codon 151 of TP53 confers gain of function activity leading to anoikis resistance and tumor progression of head and neck cancer cells.
Topics: Animals; Anoikis; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tumor; Codon; Disease Prog | 2013 |
Phosphorylation of AKT(Ser473) serves as an independent prognostic marker for radiosensitivity in advanced head and neck squamous cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoma, Squamous Cell; Chromones; Enzyme Inhib | 2015 |
S4S8-RPA phosphorylation as an indicator of cancer progression in oral squamous cell carcinomas.
Topics: Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Line, Tumor; DNA Damage; DNA Repair; Head and Neck | 2017 |
Nuclear NF-kappaB p65 phosphorylation at serine 276 by protein kinase A contributes to the malignant phenotype of head and neck cancer.
Topics: Carcinoma, Squamous Cell; Cell Cycle; Cell Nucleus; Cell Proliferation; Cyclic AMP-Dependent Protein | 2009 |
The vascular disrupting agent ombrabulin (AVE8062) enhances the efficacy of standard therapies in head and neck squamous cell carcinoma xenograft models.
Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Apoptosi | 2013 |
Phosphorylation of chk1 at serine-345 affected by topoisomerase I poison SN-38.
Topics: 14-3-3 Proteins; Adaptor Proteins, Signal Transducing; Antineoplastic Agents, Phytogenic; Camptothec | 2002 |
Interaction of OGG1 Ser326Cys polymorphism with cigarette smoking in head and neck squamous cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Carcinoma, Squamous Cell; Cysteine; DNA Glycosylas | 2006 |
Constitutive phosphorylation of aurora-a on ser51 induces its stabilization and consequent overexpression in cancer.
Topics: Animals; Aurora Kinase A; Aurora Kinases; BALB 3T3 Cells; Cell Line; Cell Line, Tumor; Gene Expressi | 2007 |