Page last updated: 2024-11-08

serine and Brain Edema

serine has been researched along with Brain Edema in 6 studies

Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.

Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)

Research Excerpts

ExcerptRelevanceReference
"Taurine release was most affected, exhibiting a greater than 9-fold increase during the hyposmotic stimulus."1.30Hyposmotically induced amino acid release from the rat cerebral cortex: role of phospholipases and protein kinases. ( Estevez, AY; O'Regan, MH; Phillis, JW; Song, D, 1999)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (50.00)18.2507
2000's1 (16.67)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhai, PP1
Xu, LH1
Yang, JJ1
Jiang, ZL1
Zhao, GW1
Sun, L1
Wang, GH1
Li, X1
Keularts, IM1
Leroy, PL1
Rubio-Gozalbo, EM1
Spaapen, LJ1
Weber, B1
Dorland, B1
de Koning, TJ1
Verhoeven-Duif, NM1
Tottene, A1
Pivotto, F1
Fellin, T1
Cesetti, T1
van den Maagdenberg, AM1
Pietrobon, D1
Kuchiwaki, H1
Inao, S1
Yamamoto, M1
Yoshida, K1
Sugita, K1
Fujikawa, DG1
Kim, JS1
Daniels, AH1
Alcaraz, AF1
Sohn, TB1
Estevez, AY1
O'Regan, MH1
Song, D1
Phillis, JW1

Other Studies

6 other studies available for serine and Brain Edema

ArticleYear
Reduction of inflammatory responses by L-serine treatment leads to neuroprotection in mice after traumatic brain injury.
    Neuropharmacology, 2015, Volume: 95

    Topics: Animals; Apoptosis; Astrocytes; Brain; Brain Edema; Brain Injuries; Cytokines; Disease Models, Anima

2015
Fatal cerebral edema associated with serine deficiency in CSF.
    Journal of inherited metabolic disease, 2010, Volume: 33 Suppl 3

    Topics: Biomarkers; Blood Glucose; Brain; Brain Edema; Child; Child, Preschool; Energy Metabolism; Fatal Out

2010
Specific kinetic alterations of human CaV2.1 calcium channels produced by mutation S218L causing familial hemiplegic migraine and delayed cerebral edema and coma after minor head trauma.
    The Journal of biological chemistry, 2005, May-06, Volume: 280, Issue:18

    Topics: Brain Edema; Calcium Channels, N-Type; Cell Line, Tumor; Craniocerebral Trauma; Humans; Leucine; Mig

2005
An assessment of progression of brain edema with amino acid levels in cerebrospinal fluid and changes in electroencephalogram in an adult cat model of cold brain injury.
    Acta neurochirurgica. Supplementum, 1994, Volume: 60

    Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Blood-Brain Barrier; Brain Edema; Brain Injuries; Cats

1994
In vivo elevation of extracellular potassium in the rat amygdala increases extracellular glutamate and aspartate and damages neurons.
    Neuroscience, 1996, Volume: 74, Issue:3

    Topics: Amygdala; Animals; Aspartic Acid; Brain Edema; Extracellular Space; Glutamic Acid; Glutamine; Glycin

1996
Hyposmotically induced amino acid release from the rat cerebral cortex: role of phospholipases and protein kinases.
    Brain research, 1999, Oct-09, Volume: 844, Issue:1-2

    Topics: Acetophenones; Alanine; Amino Acids; Animals; Arachidonic Acids; Aspartic Acid; Brain Edema; Cerebra

1999