serine and Brain Edema
serine has been researched along with Brain Edema in 6 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Taurine release was most affected, exhibiting a greater than 9-fold increase during the hyposmotic stimulus." | 1.30 | Hyposmotically induced amino acid release from the rat cerebral cortex: role of phospholipases and protein kinases. ( Estevez, AY; O'Regan, MH; Phillis, JW; Song, D, 1999) |
Research
Studies (6)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Zhai, PP | 1 |
| Xu, LH | 1 |
| Yang, JJ | 1 |
| Jiang, ZL | 1 |
| Zhao, GW | 1 |
| Sun, L | 1 |
| Wang, GH | 1 |
| Li, X | 1 |
| Keularts, IM | 1 |
| Leroy, PL | 1 |
| Rubio-Gozalbo, EM | 1 |
| Spaapen, LJ | 1 |
| Weber, B | 1 |
| Dorland, B | 1 |
| de Koning, TJ | 1 |
| Verhoeven-Duif, NM | 1 |
| Tottene, A | 1 |
| Pivotto, F | 1 |
| Fellin, T | 1 |
| Cesetti, T | 1 |
| van den Maagdenberg, AM | 1 |
| Pietrobon, D | 1 |
| Kuchiwaki, H | 1 |
| Inao, S | 1 |
| Yamamoto, M | 1 |
| Yoshida, K | 1 |
| Sugita, K | 1 |
| Fujikawa, DG | 1 |
| Kim, JS | 1 |
| Daniels, AH | 1 |
| Alcaraz, AF | 1 |
| Sohn, TB | 1 |
| Estevez, AY | 1 |
| O'Regan, MH | 1 |
| Song, D | 1 |
| Phillis, JW | 1 |
Other Studies
6 other studies available for serine and Brain Edema
| Article | Year |
|---|---|
Reduction of inflammatory responses by L-serine treatment leads to neuroprotection in mice after traumatic brain injury.
Topics: Animals; Apoptosis; Astrocytes; Brain; Brain Edema; Brain Injuries; Cytokines; Disease Models, Anima | 2015 |
Fatal cerebral edema associated with serine deficiency in CSF.
Topics: Biomarkers; Blood Glucose; Brain; Brain Edema; Child; Child, Preschool; Energy Metabolism; Fatal Out | 2010 |
Specific kinetic alterations of human CaV2.1 calcium channels produced by mutation S218L causing familial hemiplegic migraine and delayed cerebral edema and coma after minor head trauma.
Topics: Brain Edema; Calcium Channels, N-Type; Cell Line, Tumor; Craniocerebral Trauma; Humans; Leucine; Mig | 2005 |
An assessment of progression of brain edema with amino acid levels in cerebrospinal fluid and changes in electroencephalogram in an adult cat model of cold brain injury.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Blood-Brain Barrier; Brain Edema; Brain Injuries; Cats | 1994 |
In vivo elevation of extracellular potassium in the rat amygdala increases extracellular glutamate and aspartate and damages neurons.
Topics: Amygdala; Animals; Aspartic Acid; Brain Edema; Extracellular Space; Glutamic Acid; Glutamine; Glycin | 1996 |
Hyposmotically induced amino acid release from the rat cerebral cortex: role of phospholipases and protein kinases.
Topics: Acetophenones; Alanine; Amino Acids; Animals; Arachidonic Acids; Aspartic Acid; Brain Edema; Cerebra | 1999 |