serine has been researched along with Bone Loss, Osteoclastic in 7 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Since bone metastatic breast cancer is an incurable disease, causing significant morbidity and mortality, an understanding of the underlying molecular mechanisms would be highly valuable." | 5.37 | Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis. ( Edgren, H; Guise, T; Käkönen, SM; Kallioniemi, O; Kohonen, P; Nees, M; Pollari, S; Sara, H; Wolf, M, 2011) |
| "Therefore, bone resorption in vitro was reduced considerably." | 1.48 | L-plastin phosphorylation regulates the early phase of sealing ring formation by actin bundling process in mouse osteoclasts. ( Chellaiah, MA; Ma, T; Majumdar, S, 2018) |
| "Since bone metastatic breast cancer is an incurable disease, causing significant morbidity and mortality, an understanding of the underlying molecular mechanisms would be highly valuable." | 1.37 | Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis. ( Edgren, H; Guise, T; Käkönen, SM; Kallioniemi, O; Kohonen, P; Nees, M; Pollari, S; Sara, H; Wolf, M, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chellaiah, MA | 1 |
| Ma, T | 1 |
| Majumdar, S | 1 |
| Pollari, S | 1 |
| Käkönen, SM | 1 |
| Edgren, H | 1 |
| Wolf, M | 1 |
| Kohonen, P | 1 |
| Sara, H | 1 |
| Guise, T | 1 |
| Nees, M | 1 |
| Kallioniemi, O | 1 |
| Bahtiar, A | 1 |
| Nakamura, T | 1 |
| Kishida, K | 1 |
| Katsura, J | 1 |
| Nitta, M | 1 |
| Ishida-Kitagawa, N | 1 |
| Ogawa, T | 1 |
| Takeya, T | 1 |
| Takarada, T | 1 |
| Takarada-Iemata, M | 1 |
| Takahata, Y | 1 |
| Yamada, D | 1 |
| Yamamoto, T | 1 |
| Nakamura, Y | 1 |
| Hinoi, E | 1 |
| Yoneda, Y | 1 |
| Faccio, R | 1 |
| Novack, DV | 1 |
| Zallone, A | 1 |
| Ross, FP | 2 |
| Teitelbaum, SL | 2 |
| Gorski, JP | 1 |
| Abu-Amer, Y | 1 |
| Dowdy, SF | 1 |
| Clohisy, JC | 1 |
1 review available for serine and Bone Loss, Osteoclastic
| Article | Year |
|---|---|
Is all bone the same? Distinctive distributions and properties of non-collagenous matrix proteins in lamellar vs. woven bone imply the existence of different underlying osteogenic mechanisms.
Topics: 1-Carboxyglutamic Acid; Aspartic Acid; Biomechanical Phenomena; Bone and Bones; Bone Diseases; Bone | 1998 |
6 other studies available for serine and Bone Loss, Osteoclastic
| Article | Year |
|---|---|
L-plastin phosphorylation regulates the early phase of sealing ring formation by actin bundling process in mouse osteoclasts.
Topics: Actin Cytoskeleton; Actins; Animals; Bone Resorption; Cytoskeletal Proteins; Femur; Gene Expression | 2018 |
Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis.
Topics: Animals; Blotting, Western; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Cell Differentiation; | 2011 |
The l-Ser analog #290 promotes bone recovery in OP and RA mice.
Topics: 3T3 Cells; Animals; Arthritis, Rheumatoid; Bone and Bones; Bone Resorption; Cell Differentiation; Ce | 2011 |
Osteoclastogenesis is negatively regulated by D-serine produced by osteoblasts.
Topics: Alkaline Phosphatase; Amino Acid Transport Systems; Animals; Bone Marrow Cells; Bone Resorption; Cal | 2012 |
Dynamic changes in the osteoclast cytoskeleton in response to growth factors and cell attachment are controlled by beta3 integrin.
Topics: Amino Acid Sequence; Animals; Bone and Bones; Bone Resorption; Calcium Signaling; CD18 Antigens; Cel | 2003 |
TAT fusion proteins containing tyrosine 42-deleted IkappaBalpha arrest osteoclastogenesis.
Topics: Animals; Bone Marrow Cells; Bone Resorption; Cells, Cultured; Cytosol; Dentin; DNA-Binding Proteins; | 2001 |