serine has been researched along with Body Weight in 87 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
Excerpt | Relevance | Reference |
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"We compared body weight and food intake among vehicle-, olanzapine-, and olanzapine plus ALA-treated mice, and measured hypothalamic AMP-activated protein kinase (AMPK) activity by detecting levels of Thr(172) and Ser(485/491) phosphorylation, which indicate activation and inhibition of AMPK, respectively." | 7.80 | Phosphorylation of hypothalamic AMPK on serine(485/491) related to sustained weight loss by alpha-lipoic acid in mice treated with olanzapine. ( Cho, HS; Jeong, J; Kim, E; Kim, H; Lee, BI; Lee, SK; Namkoong, K; Park, JY; Park, M, 2014) |
" We recently developed a lentivirus (LV) vector that produces an insulin receptor (IR) antisense RNA sequence (IRAS) that when injected into the hypothalamus selectively decreases IR signaling in hypothalamus, resulting in increased body weight, peripheral adiposity and plasma leptin levels." | 7.77 | Obesity/hyperleptinemic phenotype adversely affects hippocampal plasticity: effects of dietary restriction. ( Evans, AN; Grillo, CA; Macht, VA; Mott, DD; Piroli, GG; Reagan, LP; Sakai, RR; Scott, KA; Wilson, SP, 2011) |
"A defect of the gene for p94 (calpain 3), a skeletal muscle-specific calpain, is responsible for limb girdle muscular dystrophy type 2A (LGMD2A), or 'calpainopathy', which is an autosomal recessive and progressive neuromuscular disorder." | 7.70 | Myopathy phenotype of transgenic mice expressing active site-mutated inactive p94 skeletal muscle-specific calpain, the gene product responsible for limb girdle muscular dystrophy type 2A. ( Arahata, K; Fukuda, R; Hata, S; Hayashi, Y; Ishiura, S; Karasuyama, H; Katsui, Y; Nakagawa, M; Nonaka, I; Ono, Y; Seyama, Y; Sorimachi, H; Suzuki, K; Tagawa, K; Taya, C; Toyama-Sorimachi, N; Yonekawa, H, 2000) |
"Insulin resistance is a hallmark of late pregnancy both in human and rat." | 5.34 | Role of insulin receptor substrate-1 serine 307 phosphorylation and adiponectin in adipose tissue insulin resistance in late pregnancy. ( Bocos, C; de Castro, J; Herrera, E; Ramos, MP; Sevillano, J, 2007) |
"We compared body weight and food intake among vehicle-, olanzapine-, and olanzapine plus ALA-treated mice, and measured hypothalamic AMP-activated protein kinase (AMPK) activity by detecting levels of Thr(172) and Ser(485/491) phosphorylation, which indicate activation and inhibition of AMPK, respectively." | 3.80 | Phosphorylation of hypothalamic AMPK on serine(485/491) related to sustained weight loss by alpha-lipoic acid in mice treated with olanzapine. ( Cho, HS; Jeong, J; Kim, E; Kim, H; Lee, BI; Lee, SK; Namkoong, K; Park, JY; Park, M, 2014) |
"05) plasma concentrations of glycine and serine, daily weight gain, and body weight without affecting body composition, while reducing plasma concentrations of ammonia, urea, and glutamine, in a dose-dependent manner." | 3.80 | Glycine is a nutritionally essential amino acid for maximal growth of milk-fed young pigs. ( Dahanayaka, S; Dai, Z; Hu, S; Jia, S; Lin, G; Wang, W; Wu, G; Wu, Z, 2014) |
" We recently developed a lentivirus (LV) vector that produces an insulin receptor (IR) antisense RNA sequence (IRAS) that when injected into the hypothalamus selectively decreases IR signaling in hypothalamus, resulting in increased body weight, peripheral adiposity and plasma leptin levels." | 3.77 | Obesity/hyperleptinemic phenotype adversely affects hippocampal plasticity: effects of dietary restriction. ( Evans, AN; Grillo, CA; Macht, VA; Mott, DD; Piroli, GG; Reagan, LP; Sakai, RR; Scott, KA; Wilson, SP, 2011) |
"In the pulmonary artery isolated from 1-week hypoxia-induced pulmonary hypertensive rats, endothelial NO production stimulated by carbachol was decreased significantly in in situ visualization using diaminofluorescein-2 diacetate and also in cGMP content." | 3.71 | Decreased endothelial nitric-oxide synthase (eNOS) activity resulting from abnormal interaction between eNOS and its regulatory proteins in hypoxia-induced pulmonary hypertension. ( Hori, M; Karaki, H; Murata, T; Ozaki, H; Sato, K, 2002) |
"A defect of the gene for p94 (calpain 3), a skeletal muscle-specific calpain, is responsible for limb girdle muscular dystrophy type 2A (LGMD2A), or 'calpainopathy', which is an autosomal recessive and progressive neuromuscular disorder." | 3.70 | Myopathy phenotype of transgenic mice expressing active site-mutated inactive p94 skeletal muscle-specific calpain, the gene product responsible for limb girdle muscular dystrophy type 2A. ( Arahata, K; Fukuda, R; Hata, S; Hayashi, Y; Ishiura, S; Karasuyama, H; Katsui, Y; Nakagawa, M; Nonaka, I; Ono, Y; Seyama, Y; Sorimachi, H; Suzuki, K; Tagawa, K; Taya, C; Toyama-Sorimachi, N; Yonekawa, H, 2000) |
"/day for 6-8 days) of L-phenylalanine which did not significantly affect body weight or brain to body weight ratios also did not significantly affect myelin accumulation or synthesis in developing rat brain." | 3.65 | Tolerance of protein and lipid synthesis to mild hyperphenylalaninemia in developing rat brain. ( Geison, RL; Siegel, FL, 1975) |
"Currently, it is known that cerebral toxoplasmosis increases dopamine levels in the brain and it is related to behavioral changes in animals and humans." | 1.62 | Social preference is maintained in mice with impaired startle reflex and glutamate/D-serine imbalance induced by chronic cerebral toxoplasmosis. ( Acquarone, M; Barbosa, HS; Gonçalves, PFR; Menezes, JRL; Neves, GA; Panizzutti, R; Perozzo, AF; Poleto, A, 2021) |
"Glycine, Ser, or Thr were supplemented on Glyequiv basis to an approximately 3% lower CP diet to achieve the same digestible Gly and Ser level as the SP diet." | 1.51 | Supplementing glycine, serine, and threonine in low protein diets for meat type chickens. ( Barekatain, R; Girish, CK; Hilliar, M; Huyen, N; Swick, RA; Wu, S, 2019) |
"Treatment with telmisartan reversed the abnormalities of PLB amount, coronary flow rate, and -dP/dt in SHRSP fatty rats." | 1.39 | Abnormal amounts of intracellular calcium regulatory proteins in SHRSP.Z-Lepr(fa)/IzmDmcr rats with metabolic syndrome and cardiac dysfunction. ( Kagota, S; Kunitomo, M; Maruyama, K; Nakamura, K; Shinozuka, K; Tada, Y; Wakuda, H, 2013) |
"ADMS rats dominantly exhibited myokymia, neuromyotonia and generalized tonic-clonic seizures." | 1.38 | Kcna1-mutant rats dominantly display myokymia, neuromyotonia and spontaneous epileptic seizures. ( Baulac, S; Ishida, S; Kaneko, S; Kuwamura, M; Mashimo, T; Nishio, T; Ohno, Y; Sakamoto, Y; Serikawa, T; Takizawa, A, 2012) |
" There were no treatment-related adverse effects on urinalysis, hematology, serum biochemistry, organ weights, gross and histopathological examination." | 1.35 | A 13-week subchronic oral toxicity study of L-serine in rats. ( Han, L; Hayamizu, K; Kaneko, I; Li, C; Li, J; Liang, A; Liu, T; Yi, Y; Zhao, Y, 2009) |
"Insulin resistance is a hallmark of late pregnancy both in human and rat." | 1.34 | Role of insulin receptor substrate-1 serine 307 phosphorylation and adiponectin in adipose tissue insulin resistance in late pregnancy. ( Bocos, C; de Castro, J; Herrera, E; Ramos, MP; Sevillano, J, 2007) |
" This combination effect was found over wide dosage ranges of AC-7700 (20-80 mg/kg) and CDDP (2." | 1.32 | Combination effect of AC-7700, a novel combretastatin A-4 derivative, and cisplatin against murine and human tumors in vivo. ( Ehara, S; Harada, K; Morinaga, Y; Nihei, Y; Suga, Y; Suzuki, M, 2003) |
"Rats were fed toxic levels of methionine with or without simultaneous dietary supplements of glycine and serine." | 1.29 | Methionine toxicity in the rat in relation to hepatic accumulation of S-adenosylmethionine: prevention by dietary stimulation of the hepatic transsulfuration pathway. ( Alakuijala, L; Eloranta, TO; Korhonen, VP; Regina, M; Smith, TK, 1993) |
"Glycine was partially effective in alleviating the growth depression caused by excess methionine." | 1.25 | Methionine toxicity in the chick: nutritional and metabolic implications. ( Baker, DH; Katz, RS, 1975) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 42 (48.28) | 18.7374 |
1990's | 7 (8.05) | 18.2507 |
2000's | 14 (16.09) | 29.6817 |
2010's | 20 (22.99) | 24.3611 |
2020's | 4 (4.60) | 2.80 |
Authors | Studies |
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Chen, Y | 1 |
Chen, X | 1 |
Li, X | 1 |
Liu, Y | 1 |
Guo, Y | 1 |
Wang, Z | 1 |
Dong, Z | 1 |
Hilliar, M | 1 |
Huyen, N | 1 |
Girish, CK | 1 |
Barekatain, R | 1 |
Wu, S | 2 |
Swick, RA | 1 |
Wang, CF | 1 |
Cai, XR | 1 |
Chi, YN | 1 |
Miao, XY | 1 |
Yang, JY | 1 |
Xiao, BK | 1 |
Huang, RQ | 1 |
Miura, N | 1 |
Matsumoto, H | 1 |
Cynober, L | 1 |
Stover, PJ | 1 |
Elango, R | 1 |
Kadowaki, M | 1 |
Bier, DM | 1 |
Smriga, M | 1 |
Acquarone, M | 1 |
Poleto, A | 1 |
Perozzo, AF | 1 |
Gonçalves, PFR | 1 |
Panizzutti, R | 1 |
Menezes, JRL | 1 |
Neves, GA | 1 |
Barbosa, HS | 1 |
Nagamachi, S | 1 |
Nishigawa, T | 1 |
Takakura, M | 1 |
Ikeda, H | 1 |
Kodaira, M | 1 |
Yamaguchi, T | 1 |
Chowdhury, VS | 1 |
Yasuo, S | 1 |
Furuse, M | 1 |
Hernández-Alonso, P | 1 |
Giardina, S | 1 |
Cañueto, D | 1 |
Salas-Salvadó, J | 1 |
Cañellas, N | 1 |
Bulló, M | 1 |
Suwandhi, L | 1 |
Hausmann, S | 1 |
Braun, A | 1 |
Gruber, T | 1 |
Heinzmann, SS | 1 |
Gálvez, EJC | 1 |
Buck, A | 1 |
Legutko, B | 1 |
Israel, A | 1 |
Feuchtinger, A | 1 |
Haythorne, E | 1 |
Staiger, H | 1 |
Heni, M | 1 |
Häring, HU | 1 |
Schmitt-Kopplin, P | 1 |
Walch, A | 1 |
Cáceres, CG | 1 |
Tschöp, MH | 1 |
Rutter, GA | 1 |
Strowig, T | 1 |
Elsner, M | 1 |
Ussar, S | 1 |
Okabe, K | 1 |
Usui, I | 1 |
Yaku, K | 1 |
Hirabayashi, Y | 1 |
Tobe, K | 1 |
Nakagawa, T | 1 |
Kobayashi, M | 1 |
Matsuda, Y | 1 |
Iwai, H | 1 |
Hiramitsu, M | 1 |
Inoue, T | 1 |
Katagiri, T | 1 |
Yamashita, Y | 1 |
Ashida, H | 1 |
Murai, A | 1 |
Horio, F | 1 |
Kagota, S | 1 |
Maruyama, K | 2 |
Tada, Y | 1 |
Wakuda, H | 1 |
Nakamura, K | 1 |
Kunitomo, M | 1 |
Shinozuka, K | 1 |
Savignac, HM | 1 |
Corona, G | 1 |
Mills, H | 1 |
Chen, L | 1 |
Spencer, JP | 1 |
Tzortzis, G | 1 |
Burnet, PW | 1 |
Kim, H | 1 |
Park, M | 1 |
Lee, SK | 1 |
Jeong, J | 1 |
Namkoong, K | 1 |
Cho, HS | 1 |
Park, JY | 1 |
Lee, BI | 1 |
Kim, E | 1 |
Wang, W | 1 |
Dai, Z | 1 |
Wu, Z | 1 |
Lin, G | 1 |
Jia, S | 1 |
Hu, S | 1 |
Dahanayaka, S | 1 |
Wu, G | 1 |
Othman, A | 1 |
Bianchi, R | 1 |
Alecu, I | 1 |
Wei, Y | 1 |
Porretta-Serapiglia, C | 1 |
Lombardi, R | 1 |
Chiorazzi, A | 1 |
Meregalli, C | 1 |
Oggioni, N | 1 |
Cavaletti, G | 1 |
Lauria, G | 1 |
von Eckardstein, A | 1 |
Hornemann, T | 1 |
Ericsson, A | 1 |
Turner, N | 1 |
Hansson, GI | 1 |
Wallenius, K | 1 |
Oakes, ND | 1 |
Wu, Y | 1 |
Song, P | 1 |
Zhang, W | 1 |
Liu, J | 1 |
Dai, X | 1 |
Liu, Z | 1 |
Lu, Q | 1 |
Ouyang, C | 1 |
Xie, Z | 1 |
Zhao, Z | 1 |
Zhuo, X | 1 |
Viollet, B | 1 |
Foretz, M | 1 |
Wu, J | 1 |
Yuan, Z | 1 |
Zou, MH | 1 |
Vanella, L | 1 |
Canestraro, M | 1 |
Lee, CR | 1 |
Cao, J | 1 |
Zeldin, DC | 1 |
Schwartzman, ML | 1 |
Abraham, NG | 1 |
Kaneko, I | 1 |
Han, L | 1 |
Liu, T | 1 |
Li, J | 1 |
Zhao, Y | 1 |
Li, C | 1 |
Yi, Y | 1 |
Liang, A | 1 |
Hayamizu, K | 1 |
Antflick, JE | 1 |
Baker, GB | 1 |
Hampson, DR | 1 |
Scattoni, ML | 1 |
Gasparini, L | 1 |
Alleva, E | 1 |
Goedert, M | 1 |
Calamandrei, G | 1 |
Spillantini, MG | 1 |
Grillo, CA | 1 |
Piroli, GG | 1 |
Evans, AN | 1 |
Macht, VA | 1 |
Wilson, SP | 1 |
Scott, KA | 1 |
Sakai, RR | 1 |
Mott, DD | 1 |
Reagan, LP | 1 |
Jiang, H | 1 |
Fang, J | 1 |
Wu, B | 1 |
Yin, G | 1 |
Sun, L | 1 |
Qu, J | 1 |
Barger, SW | 1 |
Ishida, S | 1 |
Sakamoto, Y | 1 |
Nishio, T | 1 |
Baulac, S | 1 |
Kuwamura, M | 1 |
Ohno, Y | 1 |
Takizawa, A | 1 |
Kaneko, S | 1 |
Serikawa, T | 1 |
Mashimo, T | 1 |
Dagon, Y | 1 |
Hur, E | 1 |
Zheng, B | 1 |
Wellenstein, K | 1 |
Cantley, LC | 1 |
Kahn, BB | 1 |
Murata, T | 1 |
Sato, K | 1 |
Hori, M | 1 |
Ozaki, H | 1 |
Karaki, H | 1 |
Morinaga, Y | 1 |
Suga, Y | 1 |
Ehara, S | 1 |
Harada, K | 1 |
Nihei, Y | 2 |
Suzuki, M | 2 |
Rangwala, SM | 1 |
Rhoades, B | 1 |
Shapiro, JS | 1 |
Rich, AS | 1 |
Kim, JK | 1 |
Shulman, GI | 2 |
Kaestner, KH | 1 |
Lazar, MA | 1 |
Levine, S | 1 |
Saltzman, A | 1 |
Araújo, EP | 1 |
De Souza, CT | 1 |
Gasparetti, AL | 1 |
Ueno, M | 1 |
Boschero, AC | 1 |
Saad, MJ | 1 |
Velloso, LA | 1 |
Morino, K | 1 |
Petersen, KF | 1 |
Dufour, S | 1 |
Befroy, D | 1 |
Frattini, J | 1 |
Shatzkes, N | 1 |
Neschen, S | 1 |
White, MF | 1 |
Bilz, S | 1 |
Sono, S | 1 |
Pypaert, M | 1 |
Schenck, EJ | 1 |
Brooks, CL | 1 |
Takasaki, C | 1 |
Miura, E | 1 |
Watanabe, M | 1 |
Sevillano, J | 1 |
de Castro, J | 1 |
Bocos, C | 1 |
Herrera, E | 1 |
Ramos, MP | 1 |
Tsai, GE | 1 |
Lane, HY | 1 |
Vandenberg, CM | 1 |
Liu, YC | 1 |
Tsai, P | 1 |
Jann, MW | 1 |
Vinayagamoorthi, R | 1 |
Bobby, Z | 1 |
Sridhar, MG | 1 |
Benevenga, NJ | 2 |
Harper, AE | 5 |
de Moraes, GH | 1 |
Rogler, JC | 1 |
Featherston, WR | 2 |
Betzin, B | 1 |
Bergner, H | 1 |
Simon, O | 1 |
Hiasa, Y | 1 |
Enoki, N | 1 |
Kitahori, Y | 1 |
Konishi, N | 1 |
Shimoyama, T | 1 |
Davis, AT | 1 |
Austic, RE | 1 |
Regina, M | 1 |
Korhonen, VP | 1 |
Smith, TK | 1 |
Alakuijala, L | 1 |
Eloranta, TO | 1 |
Sleet, RB | 1 |
Ross, WP | 1 |
Qu, S | 1 |
Perlaky, SE | 1 |
Organ, EL | 1 |
Crawford, D | 1 |
Cavener, DR | 1 |
Hori, K | 1 |
Saito, S | 1 |
Sato, Y | 1 |
Tagawa, K | 1 |
Taya, C | 1 |
Hayashi, Y | 1 |
Nakagawa, M | 1 |
Ono, Y | 1 |
Fukuda, R | 1 |
Karasuyama, H | 1 |
Toyama-Sorimachi, N | 1 |
Katsui, Y | 1 |
Hata, S | 1 |
Ishiura, S | 1 |
Nonaka, I | 1 |
Seyama, Y | 1 |
Arahata, K | 1 |
Yonekawa, H | 1 |
Sorimachi, H | 1 |
Suzuki, K | 1 |
Hamada, M | 1 |
Yamamoto, S | 1 |
Moriguchi, S | 1 |
Kishino, Y | 1 |
Combe, E | 1 |
Pesti, GM | 1 |
Sunde, ML | 2 |
Ngo, A | 1 |
Coon, C | 1 |
Holcenberg, JS | 1 |
Tang, E | 1 |
Dolowy, WC | 1 |
Katz, RS | 1 |
Baker, DH | 2 |
Geison, RL | 1 |
Siegel, FL | 1 |
Pathirana, C | 1 |
Grimble, RF | 1 |
Chen, XZ | 1 |
Shafer, AW | 1 |
Yun, JS | 1 |
Li, YS | 1 |
Wagner, TE | 1 |
Kopchick, JJ | 1 |
Gonçalves, CA | 1 |
Salbego, C | 1 |
Wofchuk, S | 1 |
Rocha, E | 1 |
Souza, DO | 1 |
Rathbun, WE | 1 |
Druse, MJ | 1 |
de Boer, JE | 1 |
Oostenbroek, RJ | 1 |
van Dongen, JJ | 1 |
Janssen, MA | 1 |
Soeters, PB | 1 |
Stöckl, W | 1 |
Jöchle, W | 1 |
Aoyama, Y | 1 |
Yasui, H | 1 |
Ashida, K | 1 |
Toya, RE | 1 |
Kretchmar, AL | 1 |
Price, EJ | 1 |
Girard-Globa, A | 1 |
Robin, P | 1 |
Forestier, M | 1 |
Coon, CN | 1 |
Grossie, VB | 1 |
Couch, JR | 1 |
Kruger, BJ | 1 |
Snell, EE | 1 |
Salem, SI | 1 |
Hegazi, SM | 1 |
Morcos, SR | 1 |
Boomgaardt, J | 1 |
Kurtz, DJ | 1 |
Kanfer, JN | 1 |
Adibi, SA | 1 |
Modesto, TA | 1 |
Morse, EL | 1 |
Amin, PM | 1 |
Rabbani, A | 1 |
Akrabawi, S | 1 |
Daghir, NJ | 2 |
Gaitonde, MK | 1 |
Nixey, RW | 1 |
Sharman, IM | 1 |
Cross, DL | 1 |
Ludwick, RL | 1 |
Boling, JA | 1 |
Bradley, NW | 1 |
Sifri, M | 1 |
Asmar, JA | 1 |
Tasaki, I | 1 |
Ono, T | 1 |
Baumgartner, R | 1 |
Ando, T | 1 |
Nyhan, WL | 1 |
Lakhanpal, RK | 1 |
Harrill, I | 1 |
Bowman, F | 1 |
Rogers, QR | 1 |
Chen, DM | 1 |
Katz, SI | 1 |
Edwards, CH | 1 |
Booker, LK | 1 |
Rumph, CH | 1 |
Wright, WG | 1 |
Ganapathy, SN | 1 |
Akrabawi, SS | 1 |
Kratzer, FH | 1 |
Gershoff, SN | 1 |
Gill, TJ | 1 |
Simonian, SJ | 1 |
Steinberg, AI | 1 |
Oltjen, RR | 1 |
Lehmann, RP | 1 |
Womack, M | 1 |
Sonenberg, M | 1 |
Money, WL | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Gut Microbial Remodeling With Resistant Maltodextrin for Motor and Non-motor Symptoms in Parkinson's Disease: Safety and Tolerability Study[NCT03667404] | Phase 2 | 30 participants (Anticipated) | Interventional | 2018-11-06 | Active, not recruiting | ||
Skeletal Muscle Mitochondrial Abnormalities and the Metabolic Syndrome in Pulmonary Arterial Hypertension[NCT03979482] | 30 participants (Actual) | Observational | 2019-06-01 | Completed | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
1 review available for serine and Body Weight
Article | Year |
---|---|
Relation of chemical structure to metabolic activity of vitamin B 6 .
Topics: Animals; Apoproteins; Aspartate Aminotransferases; Body Weight; Catalysis; Chemical Phenomena; Chemi | 1972 |
3 trials available for serine and Body Weight
Article | Year |
---|---|
Subchronic Tolerance Trials of Graded Oral Supplementation with Phenylalanine or Serine in Healthy Adults.
Topics: Administration, Oral; Adult; Body Weight; Dietary Supplements; Energy Intake; Female; Health; Humans | 2021 |
Changes in Plasma Metabolite Concentrations after a Low-Glycemic Index Diet Intervention.
Topics: Adult; Biomarkers; Blood Glucose; Body Weight; Diet; Diet, Fat-Restricted; Female; Glycemic Index; H | 2019 |
Utilization of wheat by adult man: nitrogen metabolism, plasma amino acids and lipids.
Topics: Adult; Amino Acids; Aminobutyrates; Blood Pressure; Blood Urea Nitrogen; Body Weight; Cholesterol; D | 1971 |
83 other studies available for serine and Body Weight
Article | Year |
---|---|
Effects of bisphenol AF on growth, behavior, histology and gene expression in marine medaka (Oryzias melastigma).
Topics: Animals; Antioxidants; Aromatase; Benzhydryl Compounds; Body Weight; Catalase; Complement C5; Diacyl | 2022 |
Supplementing glycine, serine, and threonine in low protein diets for meat type chickens.
Topics: Animal Feed; Animals; Body Weight; Chickens; Diet, Protein-Restricted; Dietary Supplements; Glycine; | 2019 |
Analgesic Activity of Jin Ling Zi Powder and Its Single Herbs: A Serum Metabonomics Study.
Topics: Analgesics; Animals; Aspirin; Biomarkers; Body Weight; Drugs, Chinese Herbal; Glycine; Glyoxylates; | 2022 |
Social preference is maintained in mice with impaired startle reflex and glutamate/D-serine imbalance induced by chronic cerebral toxoplasmosis.
Topics: Animals; Behavior, Animal; Body Weight; Brain; Glutamic Acid; Hippocampus; Mental Disorders; Mice; N | 2021 |
Dietary L-serine modifies free amino acid composition of maternal milk and lowers the body weight of the offspring in mice.
Topics: Amino Acids; Animals; Animals, Newborn; Behavior, Animal; Body Weight; Diet; Female; Lactation; Male | 2018 |
Chronic d-serine supplementation impairs insulin secretion.
Topics: Animals; Blood Glucose; Body Weight; Diet, High-Fat; Dietary Supplements; Energy Metabolism; Glucose | 2018 |
Deletion of PHGDH in adipocytes improves glucose intolerance in diet-induced obese mice.
Topics: Adipocytes; Adipose Tissue, Brown; Adipose Tissue, White; Animals; Body Weight; Diet; Female; Gene D | 2018 |
Coffee improves insulin-stimulated Akt phosphorylation in liver and skeletal muscle in diabetic KK-A(y) mice.
Topics: Adipose Tissue; Animals; Blood Glucose; Body Weight; Coffee; Diabetes Mellitus, Experimental; Hyperg | 2012 |
Abnormal amounts of intracellular calcium regulatory proteins in SHRSP.Z-Lepr(fa)/IzmDmcr rats with metabolic syndrome and cardiac dysfunction.
Topics: Animals; Benzimidazoles; Benzoates; Blood Glucose; Body Weight; Calcium; Calcium-Binding Proteins; C | 2013 |
Prebiotic feeding elevates central brain derived neurotrophic factor, N-methyl-D-aspartate receptor subunits and D-serine.
Topics: Amino Acids; Animals; Bifidobacterium; Body Weight; Brain-Derived Neurotrophic Factor; Cell Line, Tu | 2013 |
Phosphorylation of hypothalamic AMPK on serine(485/491) related to sustained weight loss by alpha-lipoic acid in mice treated with olanzapine.
Topics: AMP-Activated Protein Kinases; Animals; Anti-Obesity Agents; Antipsychotic Agents; Benzodiazepines; | 2014 |
Glycine is a nutritionally essential amino acid for maximal growth of milk-fed young pigs.
Topics: Adenosine Triphosphatases; Amino Acid Transport Systems; Ammonia; Animal Feed; Animal Nutritional Ph | 2014 |
Lowering plasma 1-deoxysphingolipids improves neuropathy in diabetic rats.
Topics: Animals; Body Weight; Diabetic Neuropathies; Eating; Electrophysiology; Hereditary Sensory and Auton | 2015 |
Pharmacological PPARα activation markedly alters plasma turnover of the amino acids glycine, serine and arginine in the rat.
Topics: Animals; Arginase; Arginine; Body Weight; Calorimetry, Indirect; Glycine; Liver; Male; Nitrogen; PPA | 2014 |
Activation of AMPKα2 in adipocytes is essential for nicotine-induced insulin resistance in vivo.
Topics: Adipocytes; Adiposity; AMP-Activated Protein Kinases; Animals; Body Composition; Body Weight; Dual S | 2015 |
Soluble epoxide hydrolase null mice exhibit female and male differences in regulation of vascular homeostasis.
Topics: Animals; Blood Vessels; Body Weight; Cytokines; Eicosanoids; Epoxide Hydrolases; Female; Gene Expres | 2015 |
A 13-week subchronic oral toxicity study of L-serine in rats.
Topics: Administration, Oral; Animals; Blood Chemical Analysis; Body Weight; Eating; Female; Food Additives; | 2009 |
The effects of a low protein diet on amino acids and enzymes in the serine synthesis pathway in mice.
Topics: Amino Acids; Animals; Body Weight; Diet; Dietary Proteins; L-Serine Dehydratase; Male; Mice; Mice, I | 2010 |
Early behavioural markers of disease in P301S tau transgenic mice.
Topics: Age Factors; Analysis of Variance; Animals; Behavior, Animal; Body Weight; Brain; Cues; Disease Mode | 2010 |
Obesity/hyperleptinemic phenotype adversely affects hippocampal plasticity: effects of dietary restriction.
Topics: Adiposity; Animals; Area Under Curve; Autoradiography; Body Weight; Corticosterone; Disease Models, | 2011 |
Overexpression of serine racemase in retina and overproduction of D-serine in eyes of streptozotocin-induced diabetic retinopathy.
Topics: Animals; Aqueous Humor; Blood Glucose; Body Weight; Cell Death; Diabetes Mellitus, Experimental; Dia | 2011 |
Kcna1-mutant rats dominantly display myokymia, neuromyotonia and spontaneous epileptic seizures.
Topics: Animals; Antiemetics; Biophysical Phenomena; Biotinylation; Body Weight; Carbamazepine; Cells, Cultu | 2012 |
p70S6 kinase phosphorylates AMPK on serine 491 to mediate leptin's effect on food intake.
Topics: Adenylate Kinase; Agouti-Related Protein; Animals; Body Weight; Cell Line; Eating; Hypothalamus; Lep | 2012 |
Decreased endothelial nitric-oxide synthase (eNOS) activity resulting from abnormal interaction between eNOS and its regulatory proteins in hypoxia-induced pulmonary hypertension.
Topics: Animals; Blotting, Western; Body Weight; Calcium; Carbachol; Cell Membrane; Cyclic GMP; Electrophore | 2002 |
Combination effect of AC-7700, a novel combretastatin A-4 derivative, and cisplatin against murine and human tumors in vivo.
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Cisplatin; Col | 2003 |
Genetic modulation of PPARgamma phosphorylation regulates insulin sensitivity.
Topics: Adiponectin; Adipose Tissue; Adipose Tissue, Brown; Alanine; Amino Acid Substitution; Animals; Blood | 2003 |
Hydropic degeneration of the anterior pituitary gland (adenohypophysis) in uremic rats.
Topics: Animals; Body Water; Body Weight; Diet; Hyponatremia; Kidney Tubular Necrosis, Acute; Male; Mercuric | 2004 |
Short-term in vivo inhibition of insulin receptor substrate-1 expression leads to insulin resistance, hyperinsulinemia, and increased adiposity.
Topics: Adipose Tissue; Animals; Body Weight; Epididymis; Glucose; Glucose Clamp Technique; Glucose Toleranc | 2005 |
Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents.
Topics: Biopsy; Blood Glucose; Blotting, Western; Body Mass Index; Body Weight; Diabetes Mellitus, Type 2; D | 2005 |
Effects of an S84E mutation of bovine growth hormone in transgenic mice.
Topics: Acetic Acid; Animals; Blotting, Southern; Body Weight; Female; Glutamic Acid; Growth Hormone; Insuli | 2006 |
Segmental and complementary expression of L-serine biosynthetic enzyme 3-phosphoglycerate dehydrogenase and neutral amino acid transporter ASCT1 in the mouse kidney.
Topics: Amino Acid Transport System ASC; Animals; Body Weight; Brain; Gene Expression Regulation; Gene Expre | 2007 |
Role of insulin receptor substrate-1 serine 307 phosphorylation and adiponectin in adipose tissue insulin resistance in late pregnancy.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Adaptor Proteins, Signal Transducing; Adiponectin; Adi | 2007 |
Disposition of D-serine in healthy adults.
Topics: Adult; Area Under Curve; Biotransformation; Body Weight; Female; Half-Life; Humans; Male; Models, St | 2008 |
Antioxidants preserve redox balance and inhibit c-Jun-N-terminal kinase pathway while improving insulin signaling in fat-fed rats: evidence for the role of oxidative stress on IRS-1 serine phosphorylation and insulin resistance.
Topics: Animals; Antioxidants; Body Weight; Cells, Cultured; Dietary Fats; Hydrogen Peroxide; Insulin; Insul | 2008 |
Alleviation of methionine and homocystine toxicity in the rat.
Topics: Amino Acids; Animals; Body Weight; Diet; Glycine; Growth; Homocystine; Male; Methionine; Rats; Serin | 1967 |
Effects of a nonspecific nitrogen deficiency on growth rate and leg problems in chicks.
Topics: Amino Acids, Essential; Animals; Body Weight; Bone Diseases, Metabolic; Chickens; Glutamates; Glutam | 1984 |
[Investigation of the feed value of straw].
Topics: Animal Feed; Animals; Arginine; Body Weight; Dietary Fiber; Digestion; Edible Grain; Glutamates; Iso | 1980 |
DL-Serine: promoting activity on renal tumorigenesis by N-ethyl-N-hydroxyethylnitrosamine in rats.
Topics: Animals; Body Weight; Carcinogens; Diethylnitrosamine; Drug Synergism; Kidney; Kidney Neoplasms; Mal | 1984 |
Threonine imbalance and the threonine requirement of the chicken.
Topics: Amino Acids; Animals; Body Weight; Chickens; Diet; Dose-Response Relationship, Drug; Female; Male; N | 1982 |
Methionine toxicity in the rat in relation to hepatic accumulation of S-adenosylmethionine: prevention by dietary stimulation of the hepatic transsulfuration pathway.
Topics: Amino Acids; Animals; Body Weight; Diet; Feeding Behavior; Glycine; Kidney; Liver; Male; Methionine; | 1993 |
Serine-enhanced restoration of 2-methoxyethanol-induced dysmorphogenesis in the rat embryo and near-term fetus.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Drug Combinations; Embryonic and Fetal Developmen | 1997 |
Mutations at the Ser50 residue of translation factor eIF-2alpha dominantly affect developmental rate, body weight, and viability of Drosophila melanogaster.
Topics: Alanine; Amino Acid Substitution; Animals; Animals, Genetically Modified; Aspartic Acid; Body Weight | 1997 |
Antitumor effects due to irreversible stoppage of tumor tissue blood flow: evaluation of a novel combretastatin A-4 derivative, AC7700.
Topics: Animals; Antineoplastic Agents; Blood Pressure; Body Weight; Disease Models, Animal; Drug Screening | 1999 |
Myopathy phenotype of transgenic mice expressing active site-mutated inactive p94 skeletal muscle-specific calpain, the gene product responsible for limb girdle muscular dystrophy type 2A.
Topics: Animals; Binding Sites; Body Weight; Calpain; Connectin; Cysteine; Female; Immunohistochemistry; Mic | 2000 |
Phagocytosis of alveolar macrophages after conagenin injection to rats.
Topics: Adjuvants, Immunologic; Animals; Body Weight; Dose-Response Relationship, Drug; Erythrocytes; Inject | 2001 |
[Influence of intestinal microflora on the amino acid composition of lamb feces].
Topics: Amino Acids; Animals; Bacterial Proteins; Body Weight; Feces; Germ-Free Life; Lysine; Male; Nitrogen | 1976 |
Sulfur amino acid and methyl donor status of corn-soy diets fed to starting broiler chicks and turkey poults.
Topics: Amino Acids, Sulfur; Animal Feed; Animals; Arginine; Betaine; Body Weight; Chickens; Choline; Cystin | 1979 |
The effect of feeding various levels of dietary glycine in a pre-experimental diet to one-day old chicks on their subsequent glycine plus serine requirement.
Topics: Animal Feed; Animals; Body Weight; Caseins; Chickens; Glycine; Male; Nutritional Requirements; Serin | 1976 |
Effect of Acinetobacter glutaminase-asparaginase treatment on free amino acids in mouse tissues.
Topics: Acetyltransferases; Acinetobacter; Amino Acids; Ammonia; Animals; Asparaginase; Asparagine; Aspartic | 1975 |
Methionine toxicity in the chick: nutritional and metabolic implications.
Topics: Adenine; Amino Acids; Animals; Arginine; Blood Glucose; Body Weight; Chickens; Glycine; Hypoglycemia | 1975 |
Relative utilization of serine and glycine by chicks.
Topics: Animal Feed; Animals; Body Weight; Chickens; Cystine; Feces; Glutamine; Glycine; Glycine max; Male; | 1975 |
Tolerance of protein and lipid synthesis to mild hyperphenylalaninemia in developing rat brain.
Topics: Acetates; Animals; Body Weight; Brain; Brain Stem; Cerebellum; Glycolipids; Leucine; Lipids; Mesence | 1975 |
Taurine and serine supplementation modulates the metabolic response to tumor necrosis factor alpha in rats fed a low protein diet.
Topics: Acute-Phase Proteins; Animals; Body Weight; Caseins; Ceruloplasmin; Dietary Proteins; Glutathione; K | 1992 |
Conversion of bovine growth hormone cysteine residues to serine affects secretion by cultured cells and growth rates in transgenic mice.
Topics: Amino Acid Sequence; Animals; Blotting, Western; Body Weight; Cattle; Cells, Cultured; Cysteine; Dis | 1992 |
Effects of undernutrition during suckling on phosphoryl serine levels in nuclear and synaptosomal proteins from cerebral cortex of rats.
Topics: Animals; Animals, Suckling; Body Weight; Cerebral Cortex; Deficiency Diseases; Dietary Proteins; DNA | 1990 |
Maternal undernutrition during lactation: effect on amino acids in brain regions of offspring.
Topics: Amino Acids; Animals; Aspartic Acid; Body Weight; Brain Chemistry; Corpus Striatum; Female; gamma-Am | 1985 |
Sequential metabolic characteristics following portacaval shunt in rats.
Topics: Amino Acids; Animals; Body Weight; Glucagon; Insulin; Isoleucine; Leucine; Male; Phenylalanine; Port | 1986 |
Corticosteroid induced changes in plasma amino acids and thyroid activity in dairy cows treated early or late during lactation.
Topics: Adrenal Cortex Hormones; Amino Acids; Animals; Body Weight; Cattle; Dexamethasone; Female; Flumethas | 1971 |
Effect of dietary protein and amino acids in a choline-deficient diet on lipid accumulation in rat liver.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Body Composition; Body Weight; Cas | 1971 |
Altered lipid and serine metabolism in graft-versus-host disease.
Topics: Animals; Body Weight; Carbon Dioxide; Chromatography, Thin Layer; Formates; Graft vs Host Disease; G | 1971 |
Long-term adaptation of weanling rats to high dietary levels of methionine and serine.
Topics: Adaptation, Biological; Adrenal Cortex Hormones; Amino Acids; Animal Nutritional Physiological Pheno | 1972 |
Glycine-serine requirement for chicks.
Topics: Age Factors; Amino Acids; Animal Feed; Animals; Body Weight; Chickens; Female; Glucose; Glycine; Mal | 1974 |
Utilization of ( 3 H)-serine by ameloblasts of rats receiving sub-mottling doses of fluoride.
Topics: Ameloblasts; Animals; Autoradiography; Body Weight; Dental Enamel; Fluorides; Fluorosis, Dental; Inj | 1972 |
Experimental protein-energy deficiency in rats. Ratio of serine+glycine to threonine as an index of deficiency.
Topics: Amino Acids; Animals; Blood Proteins; Body Weight; Chromatography; Diarrhea; Dietary Proteins; Edema | 1973 |
Sequence of limiting amino acids in gelatin for the growing chick.
Topics: Amino Acids; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Arginine; Body Weight | 1972 |
Effect of D-alanine and D-aspartic acid on the chick.
Topics: Alanine; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Asparagine; Aspartic Acid | 1972 |
Composition of myelin lipids and synthesis of 3-ketodihydrosphingosine in the vitamin B 6 -deficient developing rat.
Topics: Animals; Animals, Newborn; Body Weight; Brain; Carbon Isotopes; Cerebrosides; Chromatography, Gas; C | 1973 |
Amino acid levels in plasma, liver, and skeletal muscle during protein deprivation.
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Body Weight; Glutamates; Glutamine; Glycin | 1973 |
Effect of dietary folic acid deficiency on serine-glycine interconversion and the activity of liver serine hydroxymethyl transferase in the chick.
Topics: Animal Feed; Animals; Body Weight; Chickens; Diet; Folic Acid; Folic Acid Deficiency; Glycine; In Vi | 1973 |
The effect of deficiency of thiamine on the metabolism of (U-14C)glucose and (U-14C)ribose and the levels of amino acids in rat brain.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Body Weight; Brain; Carbon Radioisotop | 1974 |
Plasma and rumen fluid components of steers fed two sources and levels of nitrogen.
Topics: Administration, Oral; Amino Acids; Amino Acids, Essential; Ammonia; Animal Feed; Animals; Arginine; | 1974 |
Serum aminotransferase activities and plasma free amino acid concentration as criteria for pyridoxine nutritional status of chicks.
Topics: Alanine Transaminase; Amino Acids; Aminobutyrates; Ammonia; Animal Nutritional Physiological Phenome | 1972 |
Effect of dietary protein level on plasma free amino acids in the chicken.
Topics: Alanine; Amino Acids; Animals; Blood; Body Weight; Caseins; Chickens; Depression, Chemical; Dietary | 1971 |
Nonketotic hyperglycinemia.
Topics: Agranulocytosis; Amino Acid Metabolism, Inborn Errors; Benzoates; Body Weight; Carbon Isotopes; Diet | 1969 |
Effect of protein and riboflavin on plasma amino acids and hepatic riboflavin-coenzymes in the rat.
Topics: Amino Acids; Analysis of Variance; Animals; Body Weight; Caseins; Depression, Chemical; Diet; Dietar | 1969 |
The importance of dispensable amino acids for maximal growth in the rat.
Topics: Alanine; Amino Acids; Animals; Arginine; Asparagine; Aspartic Acid; Body Weight; Citrates; Diet; Glu | 1970 |
Effect of glycine and serine on methionine metabolism in rats fed diets high in methionine.
Topics: Adaptation, Physiological; Animal Feed; Animals; Body Weight; Carbon Isotopes; Glycine; Intestinal A | 1970 |
The amino acid ratio and hydroxyproline creatinine index in marginal protein-calorie malnutrition.
Topics: Amino Acids; Animals; Body Weight; Child, Preschool; Chromatography, Paper; Creatinine; Diet; Female | 1970 |
Effects of arginine or serine on the requirement for glycine by the chick.
Topics: Animals; Arginine; Body Weight; Chickens; Glycine; Serine | 1968 |
Some effects of amino acid deficiencies on antibody formation in the rat.
Topics: Amino Acids; Animals; Antibody Formation; Antigens; Antimetabolites; Body Weight; Deficiency Disease | 1968 |
Effect of diethylstilbestrol on the blood plasma amino acid patterns of beef steers fed finishing diets.
Topics: Amino Acids; Animals; Autoanalysis; Body Weight; Cattle; Chromatography, Ion Exchange; Depression, C | 1968 |
Amino acid feeding studies: effects of various nonessential nitrogen sources and of added water.
Topics: Alanine; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Aspartic Acid; Body Weigh | 1969 |
Inhibition of bovine growth hormone activity by acetyl proteins.
Topics: Acetates; Albumins; Animals; Antimetabolites; Body Weight; Caseins; Cattle; Growth Hormone; Hypophys | 1966 |