serine has been researched along with Bladder Cancer in 16 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "YY1 drives PHGDH expression in the context of mutant p53 and promotes bladder tumorigenesis, which preliminarily explains the relationship between high-frequency mutations of p53 and dysfunctional serine metabolism in bladder cancer." | 4.31 | Competition between p53 and YY1 determines PHGDH expression and malignancy in bladder cancer. ( Chen, S; He, Y; Shao, J; Shi, T; Wang, X; Yao, L; Yuan, Z; Zhang, D, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (12.50) | 18.2507 |
| 2000's | 7 (43.75) | 29.6817 |
| 2010's | 5 (31.25) | 24.3611 |
| 2020's | 2 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Li, X | 1 |
| Peng, X | 1 |
| Zhang, C | 1 |
| Bai, X | 1 |
| Li, Y | 1 |
| Chen, G | 1 |
| Guo, H | 1 |
| He, W | 1 |
| Zhou, X | 1 |
| Gou, X | 1 |
| Shi, T | 1 |
| Yuan, Z | 1 |
| He, Y | 1 |
| Zhang, D | 1 |
| Chen, S | 2 |
| Wang, X | 4 |
| Yao, L | 1 |
| Shao, J | 1 |
| Gao, F | 1 |
| Xu, T | 1 |
| Shen, Y | 1 |
| Dong, F | 1 |
| Zhong, S | 1 |
| Shen, Z | 1 |
| Greenfield, RS | 1 |
| Herd, TM | 1 |
| Date, K | 1 |
| Cooper, P | 1 |
| O'Kane, A | 1 |
| Gardiner, E | 1 |
| Maraveyas, A | 1 |
| Zhuo, DX | 1 |
| Zhang, XW | 1 |
| Jin, B | 1 |
| Zhang, Z | 1 |
| Xie, BS | 1 |
| Wu, CL | 1 |
| Gong, K | 1 |
| Mao, ZB | 1 |
| Lei, M | 1 |
| Xie, W | 1 |
| Sun, E | 1 |
| Sun, Y | 1 |
| Tian, D | 1 |
| Liu, C | 1 |
| Han, R | 2 |
| Li, N | 1 |
| Liu, M | 1 |
| Liu, L | 1 |
| Yeh, HH | 1 |
| Giri, R | 1 |
| Chang, TY | 1 |
| Chou, CY | 1 |
| Su, WC | 1 |
| Liu, HS | 1 |
| Askham, JM | 1 |
| Platt, F | 1 |
| Chambers, PA | 1 |
| Snowden, H | 1 |
| Taylor, CF | 1 |
| Knowles, MA | 1 |
| Rieger-Christ, KM | 1 |
| Lee, P | 1 |
| Zagha, R | 1 |
| Kosakowski, M | 1 |
| Moinzadeh, A | 1 |
| Stoffel, J | 1 |
| Ben-Ze'ev, A | 1 |
| Libertino, JA | 1 |
| Summerhayes, IC | 1 |
| Lai, MD | 1 |
| Lin, WC | 1 |
| Sun, YM | 1 |
| Chang, FL | 1 |
| Hoogervorst, EM | 2 |
| Bruins, W | 2 |
| Zwart, E | 1 |
| van Oostrom, CT | 1 |
| van den Aardweg, GJ | 1 |
| Beems, RB | 1 |
| van den Berg, J | 1 |
| Jacks, T | 1 |
| van Steeg, H | 2 |
| de Vries, A | 2 |
| Hernández, S | 1 |
| López-Knowles, E | 1 |
| Lloreta, J | 1 |
| Kogevinas, M | 1 |
| Amorós, A | 1 |
| Tardón, A | 1 |
| Carrato, A | 1 |
| Serra, C | 1 |
| Malats, N | 1 |
| Real, FX | 1 |
| Jonker, MJ | 1 |
| Bruning, O | 1 |
| Pennings, JL | 1 |
| Schaap, MM | 1 |
| Breit, TM | 1 |
| Herlevsen, MC | 1 |
| Theodorescu, D | 1 |
| Driscoll, B | 1 |
| T'Ang, A | 1 |
| Hu, YH | 1 |
| Yan, CL | 1 |
| Fu, Y | 1 |
| Luo, Y | 1 |
| Wu, KJ | 1 |
| Wen, S | 1 |
| Shi, XH | 1 |
| Barsky, L | 1 |
| Weinberg, K | 1 |
| Murphree, AL | 1 |
| Fung, YK | 1 |
| Rabbani, F | 1 |
| Richon, VM | 1 |
| Orlow, I | 1 |
| Lu, ML | 1 |
| Drobnjak, M | 1 |
| Dudas, M | 1 |
| Charytonowicz, E | 1 |
| Dalbagni, G | 1 |
| Cordon-Cardo, C | 1 |
16 other studies available for serine and Bladder Cancer
| Article | Year |
|---|---|
Bladder Cancer-Derived Small Extracellular Vesicles Promote Tumor Angiogenesis by Inducing HBP-Related Metabolic Reprogramming and SerRS O-GlcNAcylation in Endothelial Cells.
Topics: Animals; Endothelial Cells; Extracellular Vesicles; Glucose; Glutamine-Fructose-6-Phosphate Transami | 2022 |
Competition between p53 and YY1 determines PHGDH expression and malignancy in bladder cancer.
Topics: Animals; Cell Line, Tumor; Chromatography, Liquid; Genes, p53; Humans; Mice; Serine; Sirtuin 1; Tand | 2023 |
CIP2A depletion potentiates the chemosensitivity of cisplatin by inducing increased apoptosis in bladder cancer cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Autoantigens; Cell Line, Tumor; Cell Proliferation; Chrom | 2018 |
Signal Transduction Peptide of Tissue Factor Phosphorylated at Ser258 and the Unphosphorylated STP in Urine Are Potential Biomarkers for Bladder Cancer.
Topics: Biomarkers, Tumor; Case-Control Studies; Female; Humans; Male; Neoplasm Staging; Phosphorylation; Pi | 2019 |
CSTP1, a novel protein phosphatase, blocks cell cycle, promotes cell apoptosis, and suppresses tumor growth of bladder cancer by directly dephosphorylating Akt at Ser473 site.
Topics: Amino Acid Sequence; Animals; Apoptosis; Base Sequence; Calcineurin; Cell Cycle; Cell Division; DNA | 2013 |
microRNA-21 Regulates Cell Proliferation and Migration and Cross Talk with PTEN and p53 in Bladder Cancer.
Topics: Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Expression Regulation, Neoplastic; Gene Kn | 2015 |
Ha-ras oncogene-induced Stat3 phosphorylation enhances oncogenicity of the cell.
Topics: Amino Acid Sequence; Animals; Apoptosis; Cell Line, Tumor; Cell Transformation, Neoplastic; Cyclin D | 2009 |
AKT1 mutations in bladder cancer: identification of a novel oncogenic mutation that can co-operate with E17K.
Topics: Animals; Base Sequence; Blotting, Western; Cell Line, Tumor; Cells, Cultured; DNA Mutational Analysi | 2010 |
Novel expression of N-cadherin elicits in vitro bladder cell invasion via the Akt signaling pathway.
Topics: Blotting, Western; Cadherins; Carcinoma; Cell Line, Tumor; Chromones; Clone Cells; Collagen; Drug Co | 2004 |
Phosphorylated and hypoacetylated mutant p53 enhances cisplatin-induced apoptosis through caspase-9 pathway in the absence of transcriptional activation or translation.
Topics: Acetylation; Antineoplastic Agents; Apoptosis; Caspase 9; Caspase Inhibitors; Caspases; Cell Line, T | 2005 |
Lack of p53 Ser389 phosphorylation predisposes mice to develop 2-acetylaminofluorene-induced bladder tumors but not ionizing radiation-induced lymphomas.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; DNA Damage; Female; Genes, p53; Lymphoma; Male; Mice; M | 2005 |
Prospective study of FGFR3 mutations as a prognostic factor in nonmuscle invasive urothelial bladder carcinomas.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Cysteine; Female; Glutamic Acid; Glycine; Humans; Leucine; | 2006 |
Delayed expression of apoptotic and cell-cycle control genes in carcinogen-exposed bladders of mice lacking p53.S389 phosphorylation.
Topics: 2-Acetylaminofluorene; Animals; Apoptosis; Carcinogens; Gene Expression Regulation, Neoplastic; Gene | 2007 |
Mass spectroscopic phosphoprotein mapping of Ral binding protein 1 (RalBP1/Rip1/RLIP76).
Topics: Amino Acid Sequence; ATP-Binding Cassette Transporters; GTPase-Activating Proteins; Humans; Mass Spe | 2007 |
Discovery of a regulatory motif that controls the exposure of specific upstream cyclin-dependent kinase sites that determine both conformation and growth suppressing activity of pRb.
Topics: Amino Acid Sequence; Cell Cycle; Cyclin A; Cyclin-Dependent Kinases; Electrophoresis, Polyacrylamide | 1999 |
Prognostic significance of transcription factor E2F-1 in bladder cancer: genotypic and phenotypic characterization.
Topics: Carcinoma; Carrier Proteins; Cell Cycle Proteins; DNA-Binding Proteins; E2F Transcription Factors; E | 1999 |