serine has been researched along with B-Cell Chronic Lymphocytic Leukemia in 10 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "B lymphocytes from chronic lymphocytic leukemia (CLL) display some CD5 transcripts for CD5 containing the known exon 1 (E1A) and other CD5 transcripts containing the new exon 1 (E1B)." | 1.37 | CD5 promotes IL-10 production in chronic lymphocytic leukemia B cells through STAT3 and NFAT2 activation. ( Berthou, C; Bordron, A; Garaud, S; Hillion, S; Lemoine, S; Mageed, RA; Morva, A; Pers, JO; Renaudineau, Y; Youinou, P, 2011) |
| "We have previously shown that chronic lymphocytic leukemia (CLL) B cells secrete vascular endothelial growth factor (VEGF) in vitro, have constitutively active VEGF receptors R1 and R2, and respond to exogenous VEGF by specifically upregulating Mcl-1 and XIAP in association with decreased cell death." | 1.33 | VEGF receptors on chronic lymphocytic leukemia (CLL) B cells interact with STAT 1 and 3: implication for apoptosis resistance. ( Bone, ND; Jelinek, DF; Kay, NE; Lee, YK; Shanafelt, TD; Strege, AK, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 6 (60.00) | 24.3611 |
| 2020's | 2 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rio-Machin, A | 1 |
| Chong, SJF | 1 |
| Iskandar, K | 1 |
| Lai, JXH | 1 |
| Qu, J | 1 |
| Raman, D | 1 |
| Valentin, R | 1 |
| Herbaux, C | 1 |
| Collins, M | 1 |
| Low, ICC | 1 |
| Loh, T | 1 |
| Davids, M | 1 |
| Pervaiz, S | 1 |
| Capron, C | 1 |
| Jondeau, K | 1 |
| Casetti, L | 1 |
| Jalbert, V | 1 |
| Costa, C | 1 |
| Verhoeyen, E | 1 |
| Verhoyen, E | 1 |
| Massé, JM | 1 |
| Coppo, P | 1 |
| Béné, MC | 1 |
| Bourdoncle, P | 1 |
| Cramer-Bordé, E | 1 |
| Dusanter-Fourt, I | 1 |
| Shull, AY | 1 |
| Noonepalle, SK | 1 |
| Awan, FT | 1 |
| Liu, J | 2 |
| Pei, L | 1 |
| Bollag, RJ | 1 |
| Salman, H | 1 |
| Ding, Z | 1 |
| Shi, H | 1 |
| Mahshid, Y | 1 |
| Markoutsa, S | 1 |
| Dincbas-Renqvist, V | 1 |
| Sürün, D | 1 |
| Christensson, B | 1 |
| Sander, B | 1 |
| Björkholm, M | 1 |
| Sorg, BL | 1 |
| Rådmark, O | 1 |
| Claesson, HE | 1 |
| Rozovski, U | 1 |
| Harris, DM | 1 |
| Li, P | 2 |
| Liu, Z | 2 |
| Jain, P | 1 |
| Veletic, I | 1 |
| Ferrajoli, A | 2 |
| Burger, J | 1 |
| O'Brien, S | 1 |
| Bose, P | 1 |
| Thompson, P | 1 |
| Jain, N | 1 |
| Wierda, W | 1 |
| Keating, MJ | 2 |
| Estrov, Z | 2 |
| Hazan-Halevy, I | 1 |
| Harris, D | 1 |
| Chen, X | 1 |
| Shanker, S | 1 |
| Garaud, S | 1 |
| Morva, A | 1 |
| Lemoine, S | 1 |
| Hillion, S | 1 |
| Bordron, A | 1 |
| Pers, JO | 1 |
| Berthou, C | 1 |
| Mageed, RA | 1 |
| Renaudineau, Y | 1 |
| Youinou, P | 1 |
| Lee, YK | 1 |
| Shanafelt, TD | 1 |
| Bone, ND | 1 |
| Strege, AK | 1 |
| Jelinek, DF | 1 |
| Kay, NE | 1 |
| Smal, C | 1 |
| Van Den Neste, E | 1 |
| Maerevoet, M | 1 |
| Poiré, X | 1 |
| Théate, I | 1 |
| Bontemps, F | 1 |
10 other studies available for serine and B-Cell Chronic Lymphocytic Leukemia
| Article | Year |
|---|---|
ATM serine/threonine kinase germline mutations in chronic lymphocytic leukaemia come in different flavours.
Topics: Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Germ-Line Mutation; Humans; Leukemia, L | 2022 |
Serine-70 phosphorylated Bcl-2 prevents oxidative stress-induced DNA damage by modulating the mitochondrial redox metabolism.
Topics: Apoptosis; Cell Proliferation; Cisplatin; DNA Damage; Doxorubicin; Drug Resistance, Neoplasm; Etopos | 2020 |
Viability and stress protection of chronic lymphoid leukemia cells involves overactivation of mitochondrial phosphoSTAT3Ser727.
Topics: Apoptosis; B-Lymphocytes; Cell Survival; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Mitochondri | 2014 |
RPPA-based protein profiling reveals eIF4G overexpression and 4E-BP1 serine 65 phosphorylation as molecular events that correspond with a pro-survival phenotype in chronic lymphocytic leukemia.
Topics: Adaptor Proteins, Signal Transducing; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Euk | 2015 |
Phosphorylation of serine 523 on 5-lipoxygenase in human B lymphocytes.
Topics: Arachidonate 5-Lipoxygenase; B-Lymphocytes; Cell Line, Tumor; Cyclic AMP; Humans; Leukemia, Lymphocy | 2015 |
Constitutive Phosphorylation of STAT3 by the CK2-BLNK-CD5 Complex.
Topics: Adaptor Proteins, Signal Transducing; Casein Kinase II; CD5 Antigens; Cell Line, Tumor; Cell Membran | 2017 |
STAT3 is constitutively phosphorylated on serine 727 residues, binds DNA, and activates transcription in CLL cells.
Topics: Active Transport, Cell Nucleus; Aged; Aged, 80 and over; Apoptosis; Cell Line, Tumor; Cell Nucleus; | 2010 |
CD5 promotes IL-10 production in chronic lymphocytic leukemia B cells through STAT3 and NFAT2 activation.
Topics: Aged; Aged, 80 and over; B-Lymphocytes; Blotting, Western; CD5 Antigens; Cell Line, Tumor; Cells, Cu | 2011 |
VEGF receptors on chronic lymphocytic leukemia (CLL) B cells interact with STAT 1 and 3: implication for apoptosis resistance.
Topics: Apoptosis; Autocrine Communication; B-Lymphocytes; Cell Membrane; Cell Nucleus; DNA-Binding Proteins | 2005 |
Positive regulation of deoxycytidine kinase activity by phosphorylation of Ser-74 in B-cell chronic lymphocytic leukaemia lymphocytes.
Topics: Antibodies; Deoxycytidine Kinase; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemist | 2007 |