serine has been researched along with Autoimmune Diabetes in 17 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objective of this clinical study is to examine the association between D-serine and diabetic retinopathy (DR)." | 7.80 | Increased D-serine in the aqueous and vitreous humour in patients with proliferative diabetic retinopathy. ( Du, J; He, T; Jiang, H; Qu, J; Song, Z; Wu, S, 2014) |
| "The objective of this clinical study is to examine the association between D-serine and diabetic retinopathy (DR)." | 3.80 | Increased D-serine in the aqueous and vitreous humour in patients with proliferative diabetic retinopathy. ( Du, J; He, T; Jiang, H; Qu, J; Song, Z; Wu, S, 2014) |
| "Inflammation is detrimental to β-cell function and survival, moreover, both apoptosis and necrosis have been implicated as mechanisms of β-cell loss in T1D." | 1.91 | Inhibition of RIPK1 kinase does not affect diabetes development: β-Cells survive RIPK1 activation. ( Arroba, EN; Bertrand, MJ; Cardozo, AK; Franchimont, M; Gilglioni, EH; Gurzov, EN; Takiishi, T; Xiao, P, 2023) |
| "703 patients with type 1 diabetes mellitus from one endocrine department were included in the study." | 1.51 | Protective Effect of the ( Catrina, SB; Chatzidionysiou, K; Ekberg, NR; Eliasson, S; Falhammar, H; Gu, HF; Li, YW; Zheng, X, 2019) |
| "In this study, experimental autoimmune diabetes (EAD) mice, which subcutaneous immunization of ins1 or 2B:9-23 induced autoimmune diabetes in F1(B7." | 1.35 | One amino acid difference is critical for suppression of the development of experimental autoimmune diabetes (EAD) with intravenous injection of insulinB:9-23 peptide. ( Arai, T; Hara, K; Kameno, M; Kishi, M; Kurohara, M; Moriyama, H; Nagata, M; Okumachi, Y; Yamada, K; Yasuda, H; Yokono, K, 2008) |
| "We hypothesize that type 1 and type 2 diabetes may contribute to AD through different mechanisms; in type 2 diabetes, hyperglycemia-mediated tau cleavage may be the key feature, whereas insulin deficiency may be the major contributing factor in type 1 diabetes." | 1.35 | Increased tau phosphorylation and cleavage in mouse models of type 1 and type 2 diabetes. ( Backus, C; Feldman, EL; Hayes, JM; Kim, B; Oh, S, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.76) | 18.7374 |
| 1990's | 4 (23.53) | 18.2507 |
| 2000's | 4 (23.53) | 29.6817 |
| 2010's | 6 (35.29) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Takiishi, T | 1 |
| Xiao, P | 1 |
| Franchimont, M | 1 |
| Gilglioni, EH | 1 |
| Arroba, EN | 1 |
| Gurzov, EN | 1 |
| Bertrand, MJ | 1 |
| Cardozo, AK | 1 |
| Holm, LJ | 2 |
| Haupt-Jorgensen, M | 1 |
| Larsen, J | 1 |
| Giacobini, JD | 1 |
| Bilgin, M | 1 |
| Buschard, K | 2 |
| Ekberg, NR | 1 |
| Eliasson, S | 1 |
| Li, YW | 1 |
| Zheng, X | 1 |
| Chatzidionysiou, K | 1 |
| Falhammar, H | 1 |
| Gu, HF | 1 |
| Catrina, SB | 1 |
| Jiang, H | 1 |
| Du, J | 1 |
| He, T | 1 |
| Qu, J | 1 |
| Song, Z | 1 |
| Wu, S | 1 |
| Okumachi, Y | 1 |
| Moriyama, H | 1 |
| Kameno, M | 1 |
| Arai, T | 1 |
| Kishi, M | 1 |
| Kurohara, M | 1 |
| Yamada, K | 1 |
| Yasuda, H | 1 |
| Hara, K | 1 |
| Yokono, K | 1 |
| Nagata, M | 1 |
| Kim, B | 1 |
| Backus, C | 1 |
| Oh, S | 1 |
| Hayes, JM | 1 |
| Feldman, EL | 1 |
| Bissé, E | 1 |
| Hovasse, A | 1 |
| Preisler-Adams, S | 1 |
| Epting, T | 1 |
| Wagner, O | 1 |
| Kögel, G | 1 |
| Van Dorsselaer, A | 1 |
| Schaeffer-Reiss, C | 1 |
| Suzuki, M | 1 |
| Sasabe, J | 1 |
| Furuya, S | 1 |
| Mita, M | 1 |
| Hamase, K | 1 |
| Aiso, S | 1 |
| Mauvais-Jarvis, F | 1 |
| Boudou, P | 1 |
| Sobngwi, E | 1 |
| Riveline, JP | 1 |
| Kevorkian, JP | 1 |
| Villette, JM | 1 |
| Porcher, R | 1 |
| Vexiau, P | 1 |
| Gautier, JF | 1 |
| Prevost, G | 1 |
| Fajardy, I | 1 |
| Besmond, C | 1 |
| Balkau, B | 1 |
| Tichet, J | 1 |
| Fontaine, P | 1 |
| Danze, PM | 1 |
| Marre, M | 1 |
| Hart, LM | 1 |
| Stolk, RP | 1 |
| Jansen, JJ | 1 |
| Grobbee, DE | 1 |
| Lemkes, HH | 1 |
| Maassen, JA | 1 |
| Boutin, P | 1 |
| Gresh, L | 1 |
| Cisse, A | 1 |
| Hara, M | 1 |
| Bell, G | 1 |
| Babu, S | 1 |
| Eisenbarth, G | 1 |
| Froguel, P | 1 |
| Fountain, WC | 1 |
| Requena, JR | 1 |
| Jenkins, AJ | 1 |
| Lyons, TJ | 1 |
| Smyth, B | 1 |
| Baynes, JW | 1 |
| Thorpe, SR | 1 |
| Miyazaki, T | 1 |
| Uno, M | 1 |
| Uehira, M | 1 |
| Kikutani, H | 1 |
| Kishimoto, T | 1 |
| Kimoto, M | 1 |
| Nishimoto, H | 1 |
| Miyazaki, J | 1 |
| Yamamura, K | 1 |
| Sasaki, M | 1 |
| Sato, K | 1 |
| Maruhama, Y | 1 |
| Nordöy, A | 1 |
| Rödset, JM | 1 |
1 review available for serine and Autoimmune Diabetes
| Article | Year |
|---|---|
L-serine: a neglected amino acid with a potential therapeutic role in diabetes.
Topics: Animals; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetes, Gestational; Dietary Supple | 2019 |
16 other studies available for serine and Autoimmune Diabetes
| Article | Year |
|---|---|
Inhibition of RIPK1 kinase does not affect diabetes development: β-Cells survive RIPK1 activation.
Topics: Animals; Diabetes Mellitus, Type 1; Humans; Inflammation; Mice; Obesity; Protein Kinases; Receptor-I | 2023 |
L-serine supplementation lowers diabetes incidence and improves blood glucose homeostasis in NOD mice.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 1; Dietary Supplements; Female; Glucose Tolerance Te | 2018 |
Protective Effect of the
Topics: Adult; Aged; Aged, 80 and over; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Di | 2019 |
Increased D-serine in the aqueous and vitreous humour in patients with proliferative diabetic retinopathy.
Topics: Aged; Aqueous Humor; Case-Control Studies; Chromatography, High Pressure Liquid; Diabetes Mellitus, | 2014 |
One amino acid difference is critical for suppression of the development of experimental autoimmune diabetes (EAD) with intravenous injection of insulinB:9-23 peptide.
Topics: Amino Acid Sequence; Animals; CD4 Antigens; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type | 2008 |
Increased tau phosphorylation and cleavage in mouse models of type 1 and type 2 diabetes.
Topics: Age Factors; Animals; Blood Glucose; Brain; Cerebral Cortex; Diabetes Mellitus, Type 1; Diabetes Mel | 2009 |
Hb Riesa or β93 (F9) Cys→Ser, a new electrophoretically silent haemoglobin variant interfering with haemoglobin A1c measurement.
Topics: Amino Acid Sequence; Amino Acid Substitution; beta-Globins; Chromatography, High Pressure Liquid; Cy | 2011 |
Type 1 diabetes mellitus in mice increases hippocampal D-serine in the acute phase after streptozotocin injection.
Topics: Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Hippocampus; M | 2012 |
The polymorphism Gly574Ser in the transcription factor HNF-1alpha is not a marker of adult-onset ketosis-prone atypical diabetes in Afro-Caribbean patients.
Topics: Adult; Africa; Amino Acid Substitution; Black People; Caribbean Region; Diabetes Mellitus, Type 1; D | 2003 |
Polymorphisms of the receptor of advanced glycation endproducts (RAGE) and the development of nephropathy in type 1 diabetic patients.
Topics: Amino Acid Substitution; Arginine; Cross-Sectional Studies; Cysteine; Diabetes Mellitus, Type 1; Dia | 2005 |
Absence of the Gly40-Ser mutation in the glucagon receptor among diabetic patients in the Netherlands.
Topics: Aged; Cohort Studies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Gene Frequency; Glycine; | 1995 |
Missense mutation Gly574Ser in the transcription factor HNF-1alpha is a marker of atypical diabetes mellitus in African-American children.
Topics: Adult; Amino Acid Substitution; Black People; Child; Diabetes Mellitus, Type 1; Diabetes Mellitus, T | 1999 |
Quantification of N-(glucitol)ethanolamine and N-(carboxymethyl)serine: two products of nonenzymatic modification of aminophospholipids formed in vivo.
Topics: Aging; Amines; Diabetes Mellitus, Type 1; Erythrocyte Membrane; Gas Chromatography-Mass Spectrometry | 1999 |
Direct evidence for the contribution of the unique I-ANOD to the development of insulitis in non-obese diabetic mice.
Topics: Animals; Aspartic Acid; Base Sequence; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; F | 1990 |
Rapid changes in urinary serine and branched-chain amino acid excretion among diabetic patients during insulin treatment.
Topics: Amino Acids; Amino Acids, Branched-Chain; Blood Glucose; Diabetes Mellitus, Type 1; Energy Intake; F | 1988 |
Platelet phospholipids and their function in patients with juvenile diabetes and maturity onset diabetes.
Topics: Adult; Aged; Amino Alcohols; Blood Platelets; Blood Proteins; Cholesterol; Choline; Chromatography, | 1970 |