Page last updated: 2024-11-08

serine and Autism Spectrum Disorder

serine has been researched along with Autism Spectrum Disorder in 6 studies

Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.

Autism Spectrum Disorder: Wide continuum of associated cognitive and neurobehavioral disorders, including, but not limited to, three core-defining features: impairments in socialization, impairments in verbal and nonverbal communication, and restricted and repetitive patterns of behaviors. (from DSM-V)

Research Excerpts

ExcerptRelevanceReference
"A review of studies on the body fluid levels of neuroactive amino acids, including glutamate, glutamine, taurine, gamma-aminobutyric acid (GABA), glycine, tryptophan, D-serine, and others, in autism spectrum disorders (ASD) is given."4.95Body fluid levels of neuroactive amino acids in autism spectrum disorders: a review of the literature. ( Baker, GB; Li, XM; Rauw, G; Wang, WQ; Zheng, HF, 2017)
"Furthermore, in neurological disorders, such as traumatic brain injury and Alzheimer's disease, hyperactivation of NMDARs leads to synaptic damage."3.01Cross species review of the physiological role of D-serine in translationally relevant behaviors. ( Arizanovska, D; Emodogo, JA; Folorunso, OO; Lally, AP; Liebl, DJ; Palavicino-Maggio, CB, 2023)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (33.33)24.3611
2020's4 (66.67)2.80

Authors

AuthorsStudies
Anne, A1
Saxena, S1
Mohan, KN1
Jian, J1
Li, LG1
Zhao, PJ1
Zheng, RJ1
Dong, XW1
Zhao, YH1
Yin, BQ1
Li, S1
Cheng, H1
Li, HL1
Li, EY1
Arizanovska, D1
Emodogo, JA1
Lally, AP1
Palavicino-Maggio, CB1
Liebl, DJ1
Folorunso, OO1
Fone, KCF1
Watson, DJG1
Billiras, RI1
Sicard, DI1
Dekeyne, A1
Rivet, JM1
Gobert, A1
Millan, MJ1
Vien, TN1
Modgil, A1
Abramian, AM1
Jurd, R1
Walker, J1
Brandon, NJ1
Terunuma, M1
Rudolph, U1
Maguire, J1
Davies, PA1
Moss, SJ1
Zheng, HF1
Wang, WQ1
Li, XM1
Rauw, G1
Baker, GB1

Reviews

2 reviews available for serine and Autism Spectrum Disorder

ArticleYear
Cross species review of the physiological role of D-serine in translationally relevant behaviors.
    Amino acids, 2023, Volume: 55, Issue:11

    Topics: Animals; Autism Spectrum Disorder; Genome-Wide Association Study; Humans; Nervous System Diseases; N

2023
Body fluid levels of neuroactive amino acids in autism spectrum disorders: a review of the literature.
    Amino acids, 2017, Volume: 49, Issue:1

    Topics: Amino Acids; Autism Spectrum Disorder; Body Fluids; gamma-Aminobutyric Acid; Glutamic Acid; Glutamin

2017

Other Studies

4 other studies available for serine and Autism Spectrum Disorder

ArticleYear
Genome-wide methylation analysis of post-mortem cerebellum samples supports the role of peroxisomes in autism spectrum disorder.
    Epigenomics, 2022, Volume: 14, Issue:17

    Topics: Autism Spectrum Disorder; Catalase; Cerebellum; DNA Methylation; Epigenesis, Genetic; Glycine Plasma

2022
Mouse nerve growth factor suppresses neuronal apoptosis in valproic acid-induced autism spectrum disorder rats by regulating the phosphoinositide-3-kinase/serine/threonine kinase signaling pathway.
    Pharmacogenetics and genomics, 2023, 07-01, Volume: 33, Issue:5

    Topics: Animals; Apoptosis; Autism Spectrum Disorder; Disease Models, Animal; Humans; Mice; Phosphatidylinos

2023
Comparative Pro-cognitive and Neurochemical Profiles of Glycine Modulatory Site Agonists and Glycine Reuptake Inhibitors in the Rat: Potential Relevance to Cognitive Dysfunction and Its Management.
    Molecular neurobiology, 2020, Volume: 57, Issue:5

    Topics: Amino Acids; Animals; Autism Spectrum Disorder; Cognition; Cognition Disorders; Cycloserine; Dose-Re

2020
Compromising the phosphodependent regulation of the GABAAR β3 subunit reproduces the core phenotypes of autism spectrum disorders.
    Proceedings of the National Academy of Sciences of the United States of America, 2015, Dec-01, Volume: 112, Issue:48

    Topics: Alanine; Animals; Autism Spectrum Disorder; Behavior, Animal; Biotinylation; Cell Membrane; Dendriti

2015