Page last updated: 2024-11-08

serine and Atherogenesis

serine has been researched along with Atherogenesis in 18 studies

Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
"We conclude that berberine reduces oxidative stress and vascular inflammation, and suppresses atherogenesis via a mechanism that includes stimulation of AMPK-dependent UCP2 expression."7.77Activation of AMP-activated protein kinase is required for berberine-induced reduction of atherosclerosis in mice: the role of uncoupling protein 2. ( Liang, B; Shirwany, N; Wang, Q; Zhang, M; Zhu, Y; Zou, MH, 2011)
"We conclude that berberine reduces oxidative stress and vascular inflammation, and suppresses atherogenesis via a mechanism that includes stimulation of AMPK-dependent UCP2 expression."3.77Activation of AMP-activated protein kinase is required for berberine-induced reduction of atherosclerosis in mice: the role of uncoupling protein 2. ( Liang, B; Shirwany, N; Wang, Q; Zhang, M; Zhu, Y; Zou, MH, 2011)
"Atherosclerosis is a chronic inflammatory disease of the arteries characterized by the accumulation of inflammatory cells in the arterial wall."1.72Reducing Proteoglycan Synthesis and NOX Activity by ROCK Inhibitors: Therapeutic Targets in Atherosclerosis. ( Azizi, M; Babaahmadi-Rezaei, H; Beheshti-Nasab, H; Ghaderi-Zefrehi, H; Mehta, JL; Rezaei, M, 2022)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (22.22)29.6817
2010's9 (50.00)24.3611
2020's5 (27.78)2.80

Authors

AuthorsStudies
Millar, CL1
Anto, L1
Garcia, C1
Kim, MB1
Jain, A1
Provatas, AA1
Clark, RB2
Lee, JY1
Nichols, FC2
Blesso, CN1
Babaahmadi-Rezaei, H1
Rezaei, M1
Ghaderi-Zefrehi, H1
Azizi, M1
Beheshti-Nasab, H1
Mehta, JL2
Hu, HJ1
Wang, XH1
Zhang, TQ1
Liu, Y2
Chen, ZR1
Zhang, ZZ1
Huang, H1
Tang, HF1
Jiang, ZS1
Li, H1
Song, D1
Liu, Q1
Li, L1
Sun, X1
Guo, J1
Li, D1
Li, P1
Pan, H1
Guo, Z2
Lv, P1
Hu, K1
Wu, T1
Lin, Z1
Xue, Y1
Zhang, Y1
Nemati, R1
Dietz, C1
Anstadt, EJ1
Cervantes, J1
Dewhirst, FE1
Finegold, S1
Gallagher, JJ1
Smith, MB1
Yao, X1
Iwakawa, H1
Makabe, S1
Ito, T1
Yoshimura, T1
Watanabe, H1
Li, J1
Zhong, Z1
Yuan, J1
Chen, X1
Huang, Z1
Wu, Z1
Li, Y1
Xu, S1
Jiang, B1
Cohen, RA1
Zang, M1
Wu, C1
Hussein, MA1
Shrestha, E1
Leone, S1
Aiyegbo, MS1
Lambert, WM1
Pourcet, B1
Cardozo, T1
Gustafson, JA1
Fisher, EA1
Pineda-Torra, I1
Garabedian, MJ1
Cariou, B1
Ding, Z1
Dinnes, DL1
White, MY1
Kockx, M1
Traini, M1
Hsieh, V1
Kim, MJ1
Hou, L1
Jessup, W1
Rye, KA1
Thaysen-Andersen, M1
Cordwell, SJ1
Kritharides, L1
Fuster, JJ1
González-Navarro, H1
Vinué, A1
Molina-Sànchez, P1
Andrés-Manzano, MJ1
Nakayama, KI1
Nakayama, K1
Díez-Juan, A1
Bernad, A1
Rodríguez, C1
Martínez-González, J1
Andrés, V1
Wang, Q1
Zhang, M1
Liang, B1
Shirwany, N1
Zhu, Y1
Zou, MH1
Sugano, R1
Matsuoka, H1
Haramaki, N1
Umei, H1
Murase, E1
Fukami, K1
Iida, S1
Ikeda, H1
Imaizumi, T1
Wang, Y1
Oram, JF1
David-Dufilho, M1
Millanvoye-Van Brussel, E1
Topal, G1
Walch, L1
Brunet, A1
Rendu, F1
Pandolfi, A1
Solini, A1
Pellegrini, G1
Mincione, G1
Di Silvestre, S1
Chiozzi, P1
Giardinelli, A1
Di Marcantonio, MC1
Piccirelli, A1
Capani, F1
Consoli, A1

Trials

1 trial available for serine and Atherogenesis

ArticleYear
Polymorphonuclear leukocytes may impair endothelial function: results of crossover randomized study of lipid-lowering therapies.
    Arteriosclerosis, thrombosis, and vascular biology, 2005, Volume: 25, Issue:6

    Topics: Anticholesteremic Agents; Atherosclerosis; Cell Adhesion; Cholesterol, LDL; Cross-Over Studies; Endo

2005

Other Studies

17 other studies available for serine and Atherogenesis

ArticleYear
Gut microbiome-derived glycine lipids are diet-dependent modulators of hepatic injury and atherosclerosis.
    Journal of lipid research, 2022, Volume: 63, Issue:4

    Topics: Animals; Atherosclerosis; Bacteria; Bacteroidetes; Diet, High-Fat; Gastrointestinal Microbiome; Glyc

2022
Reducing Proteoglycan Synthesis and NOX Activity by ROCK Inhibitors: Therapeutic Targets in Atherosclerosis.
    Endocrine, metabolic & immune disorders drug targets, 2022, Volume: 22, Issue:12

    Topics: Angiotensin II; Atherosclerosis; Endothelin-1; Humans; Hypertension; Protein Serine-Threonine Kinase

2022
PLK1 promotes cholesterol efflux and alleviates atherosclerosis by up-regulating ABCA1 and ABCG1 expression via the AMPK/PPARγ/LXRα pathway.
    Biochimica et biophysica acta. Molecular and cell biology of lipids, 2022, Volume: 1867, Issue:12

    Topics: AMP-Activated Protein Kinases; Animals; Apolipoproteins E; Atherosclerosis; ATP Binding Cassette Tra

2022
miR-351 promotes atherosclerosis in diabetes by inhibiting the ITGB3/PIK3R1/Akt pathway and induces endothelial cell injury and lipid accumulation.
    Molecular medicine (Cambridge, Mass.), 2022, 09-30, Volume: 28, Issue:1

    Topics: Animals; Atherosclerosis; Azo Compounds; C-Reactive Protein; Cholesterol, LDL; Diabetes Mellitus, Ex

2022
Proline/serine-rich coiled-coil protein 1 inhibits macrophage inflammation and delays atherosclerotic progression by binding to Annexin A2.
    Clinical and translational medicine, 2023, Volume: 13, Issue:3

    Topics: Animals; Annexin A2; Atherosclerosis; Coronary Artery Disease; Inflammation; Macrophages; Mice; Mice

2023
Deposition and hydrolysis of serine dipeptide lipids of Bacteroidetes bacteria in human arteries: relationship to atherosclerosis.
    Journal of lipid research, 2017, Volume: 58, Issue:10

    Topics: Atherosclerosis; Bacteroidetes; Brain; Carotid Arteries; Dipeptides; Humans; Hydrolysis; Lipase; Lip

2017
Urinary D-serine level as a predictive biomarker for deterioration of renal function in patients with atherosclerotic risk factors.
    Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 2019, Volume: 24, Issue:2

    Topics: Aged; Atherosclerosis; Biomarkers; Female; Glomerular Filtration Rate; Humans; Kidney; Male; Middle

2019
Resveratrol improves endothelial dysfunction and attenuates atherogenesis in apolipoprotein E-deficient mice.
    The Journal of nutritional biochemistry, 2019, Volume: 67

    Topics: Animals; Atherosclerosis; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-D

2019
Activation of sterol regulatory element binding protein and NLRP3 inflammasome in atherosclerotic lesion development in diabetic pigs.
    PloS one, 2013, Volume: 8, Issue:6

    Topics: Acetylation; AMP-Activated Protein Kinases; Animals; Aorta; Atherosclerosis; Biomarkers; Carrier Pro

2013
Modulation of Macrophage Gene Expression via Liver X Receptor α Serine 198 Phosphorylation.
    Molecular and cellular biology, 2015, Jun-01, Volume: 35, Issue:11

    Topics: Animals; Atherosclerosis; Cell Line; Gene Expression; Humans; Ligands; Liver X Receptors; Macrophage

2015
PCSK9 and atherosclerosis: Beyond LDL-cholesterol lowering.
    Atherosclerosis, 2016, Volume: 253

    Topics: Atherosclerosis; Cholesterol, LDL; Humans; Proprotein Convertase 9; Proprotein Convertases; Receptor

2016
Human macrophage cathepsin B-mediated C-terminal cleavage of apolipoprotein A-I at Ser228 severely impairs antiatherogenic capacity.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2016, Volume: 30, Issue:12

    Topics: Apolipoprotein A-I; Atherosclerosis; ATP-Binding Cassette Transporters; Biological Transport; Cathep

2016
Deficient p27 phosphorylation at serine 10 increases macrophage foam cell formation and aggravates atherosclerosis through a proliferation-independent mechanism.
    Arteriosclerosis, thrombosis, and vascular biology, 2011, Volume: 31, Issue:11

    Topics: Animals; Apolipoproteins E; Arteries; Atherosclerosis; Case-Control Studies; Cell Proliferation; Cyc

2011
Activation of AMP-activated protein kinase is required for berberine-induced reduction of atherosclerosis in mice: the role of uncoupling protein 2.
    PloS one, 2011, Volume: 6, Issue:9

    Topics: Acetyl-CoA Carboxylase; Aldehydes; AMP-Activated Protein Kinases; Animals; Aorta; Apolipoproteins E;

2011
Unsaturated fatty acids phosphorylate and destabilize ABCA1 through a phospholipase D2 pathway.
    The Journal of biological chemistry, 2005, Oct-28, Volume: 280, Issue:43

    Topics: 1-Butanol; Animals; Apolipoproteins; Atherosclerosis; ATP Binding Cassette Transporter 1; ATP-Bindin

2005
Endothelial thrombomodulin induces Ca2+ signals and nitric oxide synthesis through epidermal growth factor receptor kinase and calmodulin kinase II.
    The Journal of biological chemistry, 2005, Oct-28, Volume: 280, Issue:43

    Topics: Atherosclerosis; Blotting, Western; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cal

2005
Selective insulin resistance affecting nitric oxide release but not plasminogen activator inhibitor-1 synthesis in fibroblasts from insulin-resistant individuals.
    Arteriosclerosis, thrombosis, and vascular biology, 2005, Volume: 25, Issue:11

    Topics: Adult; Atherosclerosis; Cells, Cultured; Culture Media; Female; Fibroblasts; Glucose; Glycogen; Huma

2005