serine has been researched along with Arthritis, Rheumatoid in 16 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The folate status of 29 healthy control subjects, 16 rheumatoid arthritis (RA) patients taking methotrexate (MTX), and 20 RA patients who were not being treated with MTX was estimated by an assay of the folate-dependent enzymatic synthesis of serine from formate and glycine, which is termed the C1 index." | 7.67 | Folate status of rheumatoid arthritis patients receiving long-term, low-dose methotrexate therapy. ( Altz-Smith, M; Baggott, JE; Morgan, SL, 1987) |
| "However, treatment of hyperlipidemia with statins reduces the probability of a CV event." | 5.34 | Receptor for advanced glycation end products Glycine 82 Serine polymorphism and risk of cardiovascular events in rheumatoid arthritis. ( Carroll, L; Frazer, IH; Marwick, TH; Thomas, R; Turner, M, 2007) |
| "Lysophosphatidic acid (LPA) is a pleiotropic lipid mediator that promotes motility, survival, and the synthesis of chemokines/cytokines such as interleukin-8 (IL-8) and interleukin-6 by human fibroblast-like synoviocytes from patients with rheumatoid arthritis (RAFLS)." | 3.80 | Lysophosphatidic acid-induced IL-8 secretion involves MSK1 and MSK2 mediated activation of CREB1 in human fibroblast-like synoviocytes. ( Bourgoin, SG; Fernandes, MJ; Hui, W; Poubelle, PE; Zhao, C, 2014) |
| "The folate status of 29 healthy control subjects, 16 rheumatoid arthritis (RA) patients taking methotrexate (MTX), and 20 RA patients who were not being treated with MTX was estimated by an assay of the folate-dependent enzymatic synthesis of serine from formate and glycine, which is termed the C1 index." | 3.67 | Folate status of rheumatoid arthritis patients receiving long-term, low-dose methotrexate therapy. ( Altz-Smith, M; Baggott, JE; Morgan, SL, 1987) |
| "However, treatment of hyperlipidemia with statins reduces the probability of a CV event." | 1.34 | Receptor for advanced glycation end products Glycine 82 Serine polymorphism and risk of cardiovascular events in rheumatoid arthritis. ( Carroll, L; Frazer, IH; Marwick, TH; Thomas, R; Turner, M, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (31.25) | 18.7374 |
| 1990's | 2 (12.50) | 18.2507 |
| 2000's | 2 (12.50) | 29.6817 |
| 2010's | 6 (37.50) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| He, Q | 1 |
| Jia, L | 1 |
| Wang, X | 1 |
| Feng, D | 1 |
| Mao, T | 1 |
| Zhao, C | 1 |
| Hui, W | 1 |
| Fernandes, MJ | 1 |
| Poubelle, PE | 1 |
| Bourgoin, SG | 1 |
| Terao, C | 1 |
| Yano, K | 1 |
| Ikari, K | 1 |
| Furu, M | 1 |
| Yamakawa, N | 1 |
| Yoshida, S | 1 |
| Hashimoto, M | 1 |
| Ito, H | 1 |
| Fujii, T | 1 |
| Ohmura, K | 1 |
| Yurugi, K | 1 |
| Miura, Y | 1 |
| Maekawa, T | 1 |
| Taniguchi, A | 1 |
| Momohara, S | 1 |
| Yamanaka, H | 1 |
| Mimori, T | 1 |
| Matsuda, F | 1 |
| Ross, EA | 1 |
| Naylor, AJ | 1 |
| O'Neil, JD | 1 |
| Crowley, T | 1 |
| Ridley, ML | 1 |
| Crowe, J | 1 |
| Smallie, T | 1 |
| Tang, TJ | 1 |
| Turner, JD | 1 |
| Norling, LV | 1 |
| Dominguez, S | 1 |
| Perlman, H | 1 |
| Verrills, NM | 1 |
| Kollias, G | 1 |
| Vitek, MP | 1 |
| Filer, A | 1 |
| Buckley, CD | 1 |
| Dean, JL | 1 |
| Clark, AR | 1 |
| Kuuliala, K | 1 |
| Kuuliala, A | 1 |
| Hämäläinen, M | 1 |
| Koivuniemi, R | 1 |
| Kautiainen, H | 1 |
| Moilanen, E | 1 |
| Repo, H | 1 |
| Leirisalo-Repo, M | 1 |
| Bahtiar, A | 1 |
| Nakamura, T | 1 |
| Kishida, K | 1 |
| Katsura, J | 1 |
| Nitta, M | 1 |
| Ishida-Kitagawa, N | 1 |
| Ogawa, T | 1 |
| Takeya, T | 1 |
| Mrabet, D | 1 |
| Laadhar, L | 1 |
| Sahli, H | 1 |
| Zouari, B | 1 |
| Haouet, S | 1 |
| Makni, S | 1 |
| Sellami, S | 1 |
| Dang, PM | 1 |
| Stensballe, A | 1 |
| Boussetta, T | 1 |
| Raad, H | 1 |
| Dewas, C | 1 |
| Kroviarski, Y | 1 |
| Hayem, G | 1 |
| Jensen, ON | 1 |
| Gougerot-Pocidalo, MA | 1 |
| El-Benna, J | 1 |
| Carroll, L | 1 |
| Frazer, IH | 1 |
| Turner, M | 1 |
| Marwick, TH | 1 |
| Thomas, R | 1 |
| Shido, F | 1 |
| Morimoto, K | 1 |
| Brennan, FR | 1 |
| Mikecz, K | 1 |
| Glant, TT | 1 |
| Jobanputra, P | 1 |
| Pinder, S | 1 |
| Bavington, C | 1 |
| Morrison, P | 1 |
| Nuki, G | 1 |
| Cowell, LG | 1 |
| Kim, HJ | 1 |
| Humaljoki, T | 1 |
| Berek, C | 1 |
| Kepler, TB | 1 |
| Morgan, SL | 1 |
| Baggott, JE | 1 |
| Altz-Smith, M | 1 |
| Greiling, H | 1 |
| Hanika, A | 1 |
| Krohn, E | 1 |
| Müller, G | 1 |
| Tabatabai, A | 1 |
| Brown, JH | 1 |
| Mackey, HK | 1 |
16 other studies available for serine and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Knockdown of BUB1 inhibits tumor necrosis factor-α-induced proliferation and migration of rheumatoid arthritis synovial fibroblasts by regulating PI3K/Akt pathway.
Topics: Arthritis, Rheumatoid; Cell Proliferation; Cytokines; Fibroblasts; Humans; Phosphatidylinositol 3-Ki | 2023 |
Lysophosphatidic acid-induced IL-8 secretion involves MSK1 and MSK2 mediated activation of CREB1 in human fibroblast-like synoviocytes.
Topics: Arthritis, Rheumatoid; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; | 2014 |
Brief Report: Main Contribution of DRB1*04:05 Among the Shared Epitope Alleles and Involvement of DRB1 Amino Acid Position 57 in Association With Joint Destruction in Anti-Citrullinated Protein Antibody-Positive Rheumatoid Arthritis.
Topics: Adult; Aged; Alleles; Amino Acids; Antibodies, Anti-Idiotypic; Arthritis, Rheumatoid; Asian People; | 2015 |
Treatment of inflammatory arthritis via targeting of tristetraprolin, a master regulator of pro-inflammatory gene expression.
Topics: Amino Alcohols; Animals; Apolipoproteins E; Arthritis, Rheumatoid; Cytokines; Disease Models, Animal | 2017 |
Impaired Akt Phosphorylation in Monocytes of Patients with Rheumatoid Arthritis.
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Enzyme-Linked Immunosorbent Assay; Female; Flow | 2017 |
The l-Ser analog #290 promotes bone recovery in OP and RA mice.
Topics: 3T3 Cells; Animals; Arthritis, Rheumatoid; Bone and Bones; Bone Resorption; Cell Differentiation; Ce | 2011 |
Synovial fluid and serum levels of IL-17, IL-23, and CCL-20 in rheumatoid arthritis and psoriatic arthritis: a Tunisian cross-sectional study.
Topics: Arthritis, Psoriatic; Arthritis, Rheumatoid; Case-Control Studies; Cross-Sectional Studies; Female; | 2013 |
A specific p47phox -serine phosphorylated by convergent MAPKs mediates neutrophil NADPH oxidase priming at inflammatory sites.
Topics: Amino Acid Sequence; Arthritis, Rheumatoid; Cell Line; Enzyme Activation; Enzyme Inhibitors; Geniste | 2006 |
Receptor for advanced glycation end products Glycine 82 Serine polymorphism and risk of cardiovascular events in rheumatoid arthritis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Cardiovascular Diseases; Genetic | 2007 |
Amino acid transport in human tonsillar lymphocytes with regard to patient's age and tonsillar diseases.
Topics: Adult; Age Factors; Alanine; Amino Acids; Arthritis, Rheumatoid; B-Lymphocytes; Biological Transport | 1984 |
CD44 expression by leucocytes in rheumatoid arthritis and modulation by specific antibody: implications for lymphocyte adhesion to endothelial cells and synoviocytes in vitro.
Topics: Antibodies, Monoclonal; Arthritis, Rheumatoid; Cell Adhesion; Cells, Cultured; Endothelium; Fibrobla | 1997 |
Enhanced evolvability in immunoglobulin V genes under somatic hypermutation.
Topics: Arthritis; Arthritis, Rheumatoid; DNA, Complementary; Evolution, Molecular; Gene Frequency; Genes, I | 1999 |
Folate status of rheumatoid arthritis patients receiving long-term, low-dose methotrexate therapy.
Topics: Adult; Arthritis, Rheumatoid; Diet; Erythrocytes; Female; Folic Acid; Humans; In Vitro Techniques; L | 1987 |
[Biochemical studies of the action of immunosuppressive substances].
Topics: Adult; Animals; Antineoplastic Agents; Arthritis, Rheumatoid; Carbon Isotopes; Cattle; Connective Ti | 1969 |
[Clinical experiences with a new serine-iron complex (Aktiferrin)].
Topics: Anemia, Hypochromic; Arthritis, Rheumatoid; Drug Combinations; Female; Humans; Iron; Male; Neoplasms | 1974 |
Inhibition of heat-induced denaturation of serum proteins by mixtures of nonsteroidal anti-inflammatory agents and amino acids.
Topics: Amino Acids; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Cysteine; Depression, Chemical; Flufen | 1968 |