serine has been researched along with Arrhythmias, Cardiac in 11 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This Controversies in Research article discusses the hypothesis that protein kinase A (PKA)-mediated phosphorylation of the Ryanodine Receptor (RyR) at a single serine (RyRS2808) is essential for normal sympathetic regulation of cardiac myocyte contractility and is responsible for the disturbed Ca(2+) regulation that underlies depressed contractility in heart failure." | 8.90 | Role of RyR2 phosphorylation in heart failure and arrhythmias: protein kinase A-mediated hyperphosphorylation of the ryanodine receptor at serine 2808 does not alter cardiac contractility or cause heart failure and arrhythmias. ( Houser, SR, 2014) |
| "This Controversies in Research article discusses the hypothesis that protein kinase A (PKA)-mediated phosphorylation of the Ryanodine Receptor (RyR) at a single serine (RyRS2808) is essential for normal sympathetic regulation of cardiac myocyte contractility and is responsible for the disturbed Ca(2+) regulation that underlies depressed contractility in heart failure." | 4.90 | Role of RyR2 phosphorylation in heart failure and arrhythmias: protein kinase A-mediated hyperphosphorylation of the ryanodine receptor at serine 2808 does not alter cardiac contractility or cause heart failure and arrhythmias. ( Houser, SR, 2014) |
| "Ventricular arrhythmia is the most important risk factor for sudden cardiac death (SCD) after acute myocardial infarction (MI) worldwide." | 1.56 | Cardiac-Specific Caveolin-3 Overexpression Prevents Post-Myocardial Infarction Ventricular Arrhythmias by Inhibiting Ryanodine Receptor-2 Hyperphosphorylation. ( Chen, G; Du, T; Fang, Q; Wang, DW; Wang, Y; Zhang, Z, 2020) |
| "Nausea and cardiac arrhythmias are lessened, as are the incidence and severity of hypotension." | 1.25 | Levodopa combined with peripheral decarboxylase inhibition in Parkinson's disease. ( Barbeau, A; Botez, MI; Joubert, M; Mars, H, 1972) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 5 (45.45) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, Z | 1 |
| Fang, Q | 1 |
| Du, T | 1 |
| Chen, G | 1 |
| Wang, Y | 1 |
| Wang, DW | 1 |
| Pollak, AJ | 1 |
| Haghighi, K | 1 |
| Kunduri, S | 1 |
| Arvanitis, DA | 1 |
| Bidwell, PA | 1 |
| Liu, GS | 1 |
| Singh, VP | 1 |
| Gonzalez, DJ | 1 |
| Sanoudou, D | 1 |
| Wiley, SE | 1 |
| Dixon, JE | 1 |
| Kranias, EG | 1 |
| Houser, SR | 2 |
| Herren, AW | 1 |
| Weber, DM | 1 |
| Rigor, RR | 1 |
| Margulies, KB | 1 |
| Phinney, BS | 1 |
| Bers, DM | 1 |
| Currie, S | 1 |
| Zhang, H | 1 |
| Makarewich, CA | 1 |
| Kubo, H | 1 |
| Wang, W | 1 |
| Duran, JM | 1 |
| Li, Y | 1 |
| Berretta, RM | 1 |
| Koch, WJ | 1 |
| Chen, X | 1 |
| Gao, E | 1 |
| Valdivia, HH | 1 |
| Chen, SC | 1 |
| Kennedy, BK | 1 |
| Lampe, PD | 1 |
| Tian, XL | 1 |
| Cheng, Y | 1 |
| Zhang, T | 1 |
| Liao, ML | 1 |
| Yong, SL | 1 |
| Wang, QK | 1 |
| Wang, R | 1 |
| Chen, W | 1 |
| Cai, S | 2 |
| Zhang, J | 1 |
| Bolstad, J | 2 |
| Wagenknecht, T | 2 |
| Liu, Z | 2 |
| Chen, SR | 2 |
| Meng, X | 1 |
| Xiao, B | 1 |
| Huang, X | 1 |
| Li, F | 1 |
| Trujillo, R | 1 |
| Airey, J | 1 |
| Barbeau, A | 1 |
| Mars, H | 1 |
| Botez, MI | 1 |
| Joubert, M | 1 |
2 reviews available for serine and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Role of RyR2 phosphorylation in heart failure and arrhythmias: protein kinase A-mediated hyperphosphorylation of the ryanodine receptor at serine 2808 does not alter cardiac contractility or cause heart failure and arrhythmias.
Topics: Animals; Arrhythmias, Cardiac; Calcium; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal | 2014 |
Cardiac ryanodine receptor phosphorylation by CaM Kinase II: keeping the balance right.
Topics: Amino Acid Sequence; Animals; Arrhythmias, Cardiac; Binding Sites; Calcium-Binding Proteins; Calcium | 2009 |
9 other studies available for serine and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Cardiac-Specific Caveolin-3 Overexpression Prevents Post-Myocardial Infarction Ventricular Arrhythmias by Inhibiting Ryanodine Receptor-2 Hyperphosphorylation.
Topics: Animals; Arrhythmias, Cardiac; Calcium; Caveolin 3; Death, Sudden, Cardiac; Male; Mice; Mice, Inbred | 2020 |
Phosphorylation of serine96 of histidine-rich calcium-binding protein by the Fam20C kinase functions to prevent cardiac arrhythmia.
Topics: Amino Acid Sequence; Animals; Arrhythmias, Cardiac; Calcium-Binding Proteins; Casein Kinase I; Cell | 2017 |
CaMKII Phosphorylation of Na(V)1.5: Novel in Vitro Sites Identified by Mass Spectrometry and Reduced S516 Phosphorylation in Human Heart Failure.
Topics: Action Potentials; Amino Acid Sequence; Arrhythmias, Cardiac; Calcium-Calmodulin-Dependent Protein K | 2015 |
Hyperphosphorylation of the cardiac ryanodine receptor at serine 2808 is not involved in cardiac dysfunction after myocardial infarction.
Topics: Animals; Arrhythmias, Cardiac; Calcium; Calcium Channels, L-Type; Cyclic AMP-Dependent Protein Kinas | 2012 |
Phosphorylation of connexin43 on S279/282 may contribute to laminopathy-associated conduction defects.
Topics: Animals; Arrhythmias, Cardiac; Biological Transport; Cell Communication; Cell Nucleus; Connexin 43; | 2013 |
Optical mapping of ventricular arrhythmias in LQTS mice with SCN5A mutation N1325S.
Topics: Animals; Arrhythmias, Cardiac; Asparagine; Cardiac Complexes, Premature; Long QT Syndrome; Mexiletin | 2007 |
Localization of an NH(2)-terminal disease-causing mutation hot spot to the "clamp" region in the three-dimensional structure of the cardiac ryanodine receptor.
Topics: Animals; Arrhythmias, Cardiac; Caffeine; Calcium; Cell Line; Cryoelectron Microscopy; Humans; Mice; | 2007 |
Three-dimensional localization of serine 2808, a phosphorylation site in cardiac ryanodine receptor.
Topics: Animals; Antibodies, Monoclonal; Arrhythmias, Cardiac; Calcium-Calmodulin-Dependent Protein Kinase T | 2007 |
Levodopa combined with peripheral decarboxylase inhibition in Parkinson's disease.
Topics: Adult; Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Arrhythmias, Cardiac; Benzyl Compounds; D | 1972 |